5T5W


Conserved Protein Domain Family
IL28A
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pfam15177: IL28A (this model, PSSM-Id:405797 is obsolete and has been replaced by 464546)
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Interleukin-28A
The protein family, Interleukin-28A, plays an important role in modulating the immune system. This protein family is induced by viral infection and interacts with a class II receptor. This family of proteins is found in eukaryotes. Proteins in this family are typically between 145 and 195 amino acids in length.
Links
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Statistics
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PSSM-Id: 405797
Aligned: 26 rows
Threshold Bit Score: 139.36
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
5T5W_C         3 ARGCHIAQFKSLSPRELQAFKRAKDAL-EESLLLKDCKCRSRLFPR-----------TWDLRQLQVRERPVALEAELALT 70  human
ELK18194      33 GRSCNIGKFKSLPPTEWKAFKKAKDAL-ENSL--KNQSCSFSLFPR-----------NWKLTELQVWERPMALEAELALT 98  black flying fox
ELW72398      31 GRSCNMSRFKSLSPRELEAFKKAKDAL-EKSLSLKKYSCKFRLFPR-----------DWHPRHLQMWERLMALEAELALT 98  Chinese tree shrew
XP_012402700  23 ERSCQISQFKSLSPRELETFKVAKDAY-EKAMLQTERKCSSRFFHR-----------NWDLRQLPVSVRPVVLQAELKLT 90  Tasmanian devil
K9M1U5        24 pRRCLLSHYRSLEPRTLAAAKALRDRYeEEALSWGQRNCS---FRP-----------RRDPPRPSSCARLRHVARGIADA 89  human
EOA99678      15 KKSCRLSQYGSPAYSELAEVLKFKKYY-ENIT-SKDSKCSTRLFNR-----------KWTPNELSVPDRLLLVEAELDLT 81  mallard
B4ER10        28 KKSCSLSKYQFPAPLELKAVWRMKEQF-EDIMLLTNRKCNTRLFHR-----------KWDIAELSVPDRITLVEAELDLT 95  chicken
ANQ43304      23 RRHCHMSRYRSVSPSDIRAVRRLHNEH-EKSPFSDGIKCYRKMLRQ-----------KPSVCDLQASDRLILTLERVTLA 90  tropical clawed...
XP_007491951  44 EKSCQIPQFKSLSPREMEAFTMAKDTY-EKSMLQKKRKCSSKFFHR-----------GWDFRQLQLADRPIVLEAELKLT 111 gray short-tail...
XP_002711513  34 GRDCRIDSFKSLSPRELEAFKTARDAL-EESLLLKSRRAPDPPRAPppapllrapppEW--------ERPEALEAELFMS 104 rabbit

5T5W_C        71 LKVLDATADTdpALGDVLDQPLHTLHHILSQLRACIQPQPTAGPR--TRGRLHRWLHRL-----QEAPKKESPGCLEASV 143 human
ELK18194      99 LKVLETKADS--SLGDILDQPLHTLRHIHSELQACVSPQPTASPR--PHGRLHHWLHRL-----QKAPKKVSQDCLESTV 169 black flying fox
ELW72398      99 LRVLGSVADS--ALGDVLDQPLHVLRHIHSLLQACVPAQ--------PQGHLPSWLLQL-----QEVEKKKSPGCLKAAA 163 Chinese tree shrew
XP_012402700  91 LEVLKAVTKP--ELDSVLAQPLQTLSHIHQEIQSCVTSQTSKEHK--LPGRLKNWLNKL-----SEA-RKEPQNCLEASI 160 Tasmanian devil
K9M1U5        90 QAVLSGLHRS--ELLPGAGPILELLAAAGRDVAACLELARPGSSRkvPGAQKRR----------HKPRRADSPRCRKASV 157 human
EOA99678      82 IAVLAHPTVD--KLAEKSQQPLAFFTQAREDLRGCVAAEAPSHQ---PSGKLRHWLQKL-----ETAKKTETASCLEYST 151 mallard
B4ER10        96 ITVLTNPTTQ--RLAETCQQPLAFLTQVQEDLRDCLALE---APShqPSGKLRHWLQKL-----KTAKKKETAGCLEASA 165 chicken
ANQ43304      91 VDVLTNMTES--PLAKLLSLPLTMLLSLEDDLKICRKSPLYSDP---PSEQLMPWLHHL-----KHFREKVSSECVQDAV 160 tropical clawed...
XP_007491951 112 LEVLKGIQNP--ELQDVLIQPLQTLSHIYREIQSCVTPLPSRGHR--LPGRPNNWLHRL-----TEA-GKESQSCLEASV 181 gray short-tail...
XP_002711513 105 LKVLEAMEDS--ARGHVLEQPLRTLRHIHTQLRG-LSPQQTASAHhpPVPKRRGRLHPLatpgsQEAPKKEAPACLEASV 181 rabbit

5T5W_C       144 TFNLFRLLaRDLNCVAS 160 human
ELK18194     170 TFNLFRLLtRDLKpqga 186 black flying fox
ELW72398     164 TFNLFRLLnQNLKCVAS 180 Chinese tree shrew
XP_012402700 161 MLNLFRLLtQDLRCVAY 177 Tasmanian devil
K9M1U5       158 VFNLLRLLtWELRLAAH 174 human
EOA99678     152 IVHLFQVL-HDLGCVA- 166 mallard
B4ER10       166 ILHIFQVL-NDLRCAAQ 181 chicken
ANQ43304     161 LLSLTQLLiEDIMCWAN 177 tropical clawed frog
XP_007491951 182 MLTLPRLPdTDLRffls 198 gray short-tailed opossum
XP_002711513 182 IFILFRLLtRDLKCVAS 198 rabbit
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