Conserved Protein Domain Family
PcbC

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COG3491: PcbC (this model, PSSM-Id:226022 is obsolete and has been replaced by 442714)
Isopenicillin N synthase and related dioxygenases [Secondary metabolites biosynthesis, transport and catabolism]
Statistics
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PSSM-Id: 226022
Aligned: 11 rows
Threshold Bit Score: 364.765
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
729862    20 EQNRIMPLIDFGPYVNQEPGAHERIIQQLRAACESTGFFQIVNSPISPDVVKNAFRASKQFFELPFDEKLTLSKDMFsnr 99  fission yeast
16124455   1 MSTSAIDPVSFSLYAK----DFTRFAQELGASFERYGFAVLSDYDLDQARIDAAVDSAKAFFALPVETKKQYAGVKG--- 73  Caulobacter crescen...
15792523   1 ---MNLPILDLQAYEK----DKSTFLKNLREIASKIGFFYLINTSIDKNLNEKLFKLGKEFFNLSRSSKELISMVHS--- 70  Campylobacter jejuni
15595345   1 --MDRLPIIDIAPLYGADRGAWNDVARRIDQACREWGFFYIAGHPLPAARFEALLAAAREFFALPVEEKLKIDITRS--- 75  Pseudomonas aerugin...
15599386   1 MSTPSLPIIDIAALAGSDPAARRSVAVRIDRACREQGFFYVVGHGVEAQLVERLERLARQFFALDETSKLRWRMELGg-- 78  Pseudomonas aerugin...
17549748   1 --MTDLTTFHLPERITN-TEAHRELGQAMVKAWRTDGIFQITLSKPQEQTTDEAFAESRQFFSQDFETKSRHVSALT--- 74  Ralstonia solanacearum
19076026   1 MGSLEVPCIDLSENDT------SIVVKELLDACKNWGFVSLKNHGIPLDEIDRTFKLADKFFDIPVEEKQKYLFKGG--- 71  fission yeast
16121598  22 TS--TLPLLDLSLLSGSDT-ERQAFLTALRHAARDVGFFYLTGHGIDTSLLRQIQILSRQFFALSDEEKLSIAMIRS--- 95  Yersinia pestis
13470412   1 -MTQDIETIGIADLFGPPSPGRDRADISIMAAASGIGFMAVRDFPGDAWLMPERRAQLLHIFALPDTEKQKLLRWNFd-- 77  Mesorhizobium loti
13475741  27 DMPRIVPVLDLSRLEQGAS-ERRTFLADLRSASRDIGFFYLAGHGISWAEISEVLTASRQFFALPEADKLAIEMVKS--- 102 Mesorhizobium loti
13488351     --------------------------------------------------------------------------------     Mesorhizobium loti
729862   100 gyelmedfvlegeedssspleisgidfeagsypgeaplpPSSIGYVLPPSSLANGEGssMFDADMTTSNAVAhgdesisn 179 fission yeast
16124455  74 ----------------------------------------GARGYIPFGVETAKGADhyDLKEFWHMGRDLP-------- 105 Caulobacter crescen...
15792523  71 ---------------------------------------PQFRGYTSEGFEYTAGSK--DYREQLDIGTERDa------- 102 Campylobacter jejuni
15595345  76 ---------------------------------------RNHRGYGAIATEQLDPALpsDFKETFDMALHLP-------- 108 Pseudomonas aerugin...
15599386  79 ---------------------------------------RAWRGYFPLGGELTSNRP--DWKEGLYLGSELD-------- 109 Pseudomonas aerugin...
17549748  75 -----------------------------------------YSGYIASREEVTAGEA--DYSEIFTICPDIG-------- 103 Ralstonia solanacearum
19076026  72 ---------------------------------------RLHSGYTGHFGEKLDMEH----QSRGDLKESYD-------- 100 fission yeast
16121598  96 ---------------------------------------PHFRGYNRAASEFTRGQP--DWREQFDIGAERTp------- 127 Yersinia pestis
13470412  78 ---------------------------------------RTRKNVYRGWFSLQPTAV--SYKEGIDMGPDIAd------- 109 Mesorhizobium loti
13475741 103 ---------------------------------------SQFRGYTRAGGELTKGRE--DWREQLDIGVERQa------- 134 Mesorhizobium loti
13488351     --------------------------------------------------------------------------------     Mesorhizobium loti
729862   180 efresfyfgnDNLSKDRLLRPFQGPNKWPstAGSSFRKALVKYHDQMLAFANHVMSLLAESLELSPDAFDEF-CSDPTTS 258 fission yeast
16124455 106 ------------PGHRFR--AHMADNVWPa-EIPAFKHDVSWLYNSLDGMGGKVLEAIATYLKLERDFFKPT-VQDGNSV 169 Caulobacter crescen...
15792523 103 ---------lNWNLNSPLWQRLEGPNLWPs-EIPELKKTFLTWHKQTKKACLKLLKAFAQALDLPNNAFDKLyGENSYEH 172 Campylobacter jejuni
15595345 109 ----------AEHPDVRAGKSFYGPNRHP--DLPGWEALLEGHYADMLALARTVLRALAIALGIEEDFFDRR-FEQPVSV 175 Pseudomonas aerugin...
15599386 110 ----------AEHPEVRAGTPLHGANLFP--EVPGLRETLLEYLDATTRVGHRLMEGIALGLGLEADYFAARyTGDPLIL 177 Pseudomonas aerugin...
17549748 104 ----------LEDARVRENLPCHGPVPWP---GAAYRDRMKAFMGMLGTFGERLLQLIALGLDLDDMDTFTRlTQDGWHH 170 Ralstonia solanacearum
19076026 101 ------------LAGFPD--PK-LENLCP--FIAEHMDEFLQFQRHCYKLTLRLLDFFAIGFGIPPDFFSKS-HSSEEDV 162 fission yeast
16121598 128 ---------lPQIAGAPSWTRLQGPNQWPt-ALPELKPVLLQWQEEMTRMSLRLLRAFALALDLDEQAFDALyGDKPNEH 197 Yersinia pestis
13470412 110 ---------aAGVSASDDPLCEPTPLPTEd-ALPGWRAAAADYYRAMETVSNALMRSIARGLDLPETIFDSY-FEHGIST 178 Mesorhizobium loti
13475741 135 ---------iAQGPGTPAWTRLQGPNQWPa-ALPDLKPALLAWQSKVTAVAIRLLKAFAQSLDQPEDAFDPIySSEPNHR 204 Mesorhizobium loti
13488351     --------------------------------------------------------------------------------     Mesorhizobium loti
729862   259 IRLLRYPSSPNRLGVQ--------------------EHTDADALTLMSQDNVKGLEILDPVs------------------ 300 fission yeast
16124455 170 LRLLHYPPIPKDATGVra-----------------gAHGDINTITLLLGAEEGGLEVLDRD------------------- 213 Caulobacter crescen...
15792523 173 CKIIHYP-KSSKNITQgv-----------------gSHKDGGLITFVFQEKQSGFEAFID-------------------- 214 Campylobacter jejuni
15595345 176 FRLIHYPPASARQSADqpg---------------agAHTDYGCVTLLYQDAAGGLQVQNRQ------------------- 221 Pseudomonas aerugin...
15599386 178 FRLFNYPSQPVPEGLDvqw--------------gvgEHTDYGLLTLLHQDAIGGLQVRTP-------------------- 223 Pseudomonas aerugin...
17549748 171 MRVLRFPTVQSSENARgi-----------------gAHTDYGMLVIAAQDDVGGLYVRPPIegerrnrnwlpsestagvy 233 Ralstonia solanacearum
19076026 163 LRLLKYSIPEGVERREdde--------------dagAHSDYGSITLLFQRDAAGLEIRPPNfv----------------- 211 fission yeast
16121598 198 IKLIRYPGREATQSGQgv-----------------gAHKDSGFLSFLLQDTQRGLQVEVEE------------------- 241 Yersinia pestis
13470412 179 LRLIRYPLRDANAGIDisgpefsvvhkgetrtiigrEHADSGFVTLLAQDGVEGLQAKNLA------------------- 239 Mesorhizobium loti
13475741 205 MKIVRYPGRDTTGGDQgv-----------------gAHKDGGFLTLLLQDDNKGLQVDYD-------------------- 247 Mesorhizobium loti
13488351     --------------------------------------------------------------------------------     Mesorhizobium loti
729862   301 ---NCFLSVSPAPGALIANLGDIMAILTNNRYKSSMHRVCNNSG----SDRYTIPFFLQGNIDYVVAP--LPGLGPSTAE 371 fission yeast
16124455 214 ---GQWLPINPPPGCLVINIGDMLERLTNNVLPSTVHRVVNPPPerrgVPRYSTPFFLHFASDYEIK---TLQNCVTAEN 287 Caulobacter crescen...
15792523 215 ---GKWLSIPPLENSVVVNIGEFLELATNGYLKATIHRVNLSPK-----ERFSIAYFLGVQLDKDIP---IFKLNPELAK 283 Campylobacter jejuni
15595345 222 ---GEWIDAPPIDGTFVVNIGDMMARWSNDRYRSTPHRVISPRG----VHRYSMPFFAEPHMDTEIR---CLPGCFDADN 291 Pseudomonas aerugin...
15599386 224 ---QGWLEAPPIPGSFVCNLGDMLERMTGGLYRSTPHRVARNTSg---RDRLSFPLFFDPNFHARVQPieGLPEVPEQDD 297 Pseudomonas aerugin...
17549748 234 ehdDGWNFIKPMPAVLTVFPGDFLQFLTGGHLLSTPHKVRLNTR-----ERFAMAYFHEPNFDAWVEP-----LEADAAV 303 Ralstonia solanacearum
19076026 212 -kdMDWIKVNVQPDVVLVNIADMLQFWTSGKLRSTVHRVRIDPGv---KTRQTIAYFVTPDPETPLSP--LFEEKTGKDI 285 fission yeast
16121598 242 ---GQWIDAVPREGTFVVNIGELLELASNGYLRATVHRVETPPAg---IDRLSIAFFLGARLDAVVP---LYPLSAALAA 312 Yersinia pestis
13470412 240 ---GEWIDVPPANSTLAVNFGQLLERWTGGRVRATRHRVIAPKT-----ARFSIPFFYEPRVDAEIAP--LP-LSGAEPF 308 Mesorhizobium loti
13475741 248 ---GSWVDVDPIPGTLVVNIGELLELASNGYLRATVHRVVTPPAg---VERISVPFFFSARLDATIP---LLGLSEELAA 318 Mesorhizobium loti
13488351   1 -------------------------------------------------------------MRRTT----LLNLPEALAA 15  Mesorhizobium loti
729862   372 PIAVED------LLRDHFQNSYTSHTTSLEVA 397 fission yeast
16124455 288 PDRYPEs--------ITADEFLQQRLREIKLA 311 Caulobacter crescentus CB15
15792523 284 ESKGVDtdpknpLLRNVASNYFKRMIRSHPDV 315 Campylobacter jejuni
15595345 292 PPKYPPttcgdwLTSRFAQTYAYRRGETA--- 320 Pseudomonas aeruginosa PA01
15599386 298 SARRWDqanvhaFHGEYGDYLLNKVAKVFPQL 329 Pseudomonas aeruginosa PA01
17549748 304 APIHYGthftnmFMRCYPKRITTRRIMENGLL 335 Ralstonia solanacearum
19076026 286 ETVTAG------EWIDGRINFTYGYSAPPKGY 311 fission yeast
16121598 313 EARGPAsdphnpLFRDVGLNYLKGRLRSHPDV 344 Yersinia pestis
13470412 309 EPFLYGd-----YLWEAATNFVEMAGIKHLRQ 335 Mesorhizobium loti
13475741 319 QARGPAsdpdnpLFRDVGTNVLKSRLRSHPDV 350 Mesorhizobium loti
13488351  16 EPRGPAsdpdnpLLRDIGTNVLKCRLHSHPDV 47  Mesorhizobium loti
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