Conserved Protein Domain Family
PRK11646

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PRK11646: PRK11646 
multidrug efflux MFS transporter MdtH
Statistics
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PSSM-Id: 183255
Aligned: 94 rows
Threshold Bit Score: 581.248
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
33519909    1 MNSISKVRKLGKYFLIIDNMFVVIGFYAVFPLISIHFVEQLGWTAFLVGFALGLRQFIQQGLGIIGGAFADKLGAKPMIV 80 
145300316   1 --MVERARRLGRWFLALDSLLVILGFFVVMPMISLRFVDQQGWAAGIVGLALGLRQLTQQGLGVLGGSLADKFGARPLIV 78 
85059223    1 MSSVSQARSLGKYFLLMDNMLVVMGFYVVFPLISIRFVDQLGWAALLVGIALGLRQFIQQGLGIFGGAFADRLGAKPMII 80 
50121449    1 MPLMSQARSLGKYFLLLDNMLVVLGFFVVFPLISIRFVDQLGWAALLVGIALGLRQFIQQGLGIFGGAIADRFGAKPMII 80 
253688189   1 MPLMSQARSLGKYFLLLDNMLVVLGFFVVFPLISIRFVDDLGWAALLVGIALGLRQFIQQGLGIFGGAIADRFGAKPMII 80 
71892232    1 MYTISKARRLGKCFLIIDNMFVVIGFYVVFPLISIYFVEQLGWGAFLVGFALGLRQFIQQGLGIFSGAFADKLGAKPMIV 80 
242239609   1 MPLMTQARSLGKYFLLLDNMLVILGFFVVFPLISIRFVDQMGWAALTVGIALGLRQFTQQGLGIFGGAIADRFGAKPMIV 80 
271500750   1 MSLMAQARSLGKYFLLLDNMLVILGFFVVFPLISIRFVDQLGWAALTVGIALGLRQFTQQGLGIFGGAIADRFGAKPMIV 80 
251789876   1 ---MTQARSLGKYFLLLDNMLVVLGFFVVFPLISIRFVDQMGWAALTVGIALGLRQFTQQGLGIFGGAIADRFGAKPMIV 77 
162139369   1 MSSVSQARSLGKYFLLMDNILVVMGFYMVFPLISIRFVDQLGWTALLVGIALGLRQFIQQGLGIFGGAFADKLGAKPMII 80 
33519909   81 SGLFMRTIGFIIMSLAHTPTLLCAACILSALGGTLFDPPRTALVIKLIRPWKLGRFYSILMLEDSICAIIGITLGSWLLq 160
145300316  79 GGMLLRAAGFASLAYAQSGLELILSCIISGLGGCLFDPPRAALVIKFTRPRQRGRYISLLMMLESAGAVVGALLGSWLL- 157
85059223   81 AGMLMRALGFVLMGIADEPWLLWLSCALSALGGTLFDPPRTALVIKLTRPWERGRFYSLLMMQDSACSVIGALLGSWLL- 159
50121449   81 TGMLLRASGFVFMAIADEPWLLWLSCALSGLGGTLFDPPRTALVIKLIRPQERGRFYSLLMMQDSAGAVIGALLGSWLL- 159
253688189  81 TGMLLRASGFVFMAIADEPWLLWLSCALSGLGGTLFDPPRTALVIKLIRPQERGRFYSLLMMQDSAGAVIGALIGSWLL- 159
71892232   81 SGLFIRTLGFIIMSVANTPLLLCLSCMLSALGGTLFDPPRTALVIKLVRPWELGRFYSVLMLEDSMCAIIGIVLGTWLL- 159
242239609  81 AGMLLRASGFVLMALAETPLLLMLSCILSALGGTLFEPPRNAIVIKLTRPHERSRFYSLLMMQDNAGAVLGALLGSWLM- 159
271500750  81 TGMLLRASGFAFMALATTPLMLMLSCVLSALGGTLFEPPRNAMVIKLTRPHERSRFFSLLMMQDNAGAVIGALIGSWLM- 159
251789876  78 TGMLLRASGFVFMALATTPLMLMLSCVLSALGGTLFEPPRNAMVIKLTRPHERSRFFSLLMMQDNAGAVIGALIGSWLM- 156
162139369  81 TGMLMRALGFIFMGIADKPWLLWVSCILSALGGTLFDPPRTALVMKLTRPWERGRFYSLLMIQDSTCAMVGALLGSWLL- 159
33519909  161 QYNFQLVCLTGAILFFIAGMFNAWRLPAYKISSSHLSLLDGIKQVLHNQKFIIYTLTLSGYYILSAQVMLMLPIRMHEIS 240
145300316 158 NFDFEYVCLLGAGLFVCAALCNLLILPPYKLSQRPTPIRAGLGQVLADKAFCRLVLILSGYYALWVQVMLIFPILVKQMA 237
85059223  160 RYDFKLVCLAGAVLFVFAAIFNAWLLPGYRISTVRAPMLEGMRRVLRDQRFVTYVLTLTGYYMLSVQVMLMLPIRINEVA 239
50121449  160 QYDFEVVCWVGAVIFVLVAGLNAWLLPAYRISTVRTPIKEGLMRVIRDRRFLMYVLTLTGYYMLAVQVLLMLPIMVNEIA 239
253688189 160 QYDFEIVCWTGAVIFVLAAALNAWLLPAYRISTVKTPILEGLTRVIRDRRFLMYVLTLTGYYMLAVQVLLMLPIMVNEIA 239
71892232  160 QYNFKLVCFTGAILFFIAGVFNAWRLPAYKISSSHASLLEGIKKVLNNQRFVIYVFTLTGYYILSAQVMLMLPIRIHEVS 239
242239609 160 QYNFNVVCWTGAAIFVLIGLLNAWLLPAYRISTTRTPILEGMSRVLRDRRFVTYVLTLTGYYMLSVQVLLMMPIMVNELA 239
271500750 160 QYNFSVVCWVGASVFVLVALLNAWLLPAYRISTTRTPIREGMMRVMRDRRFVVYVLTLTGYFMLGVQVLLMMPIMVNELA 239
251789876 157 QYNFSVVCWAGAAVFVLAAALNALLLPAYRISTTRTPIREGMMRVMRDRRFVVYVLTLTGYFMLGVQVLLMMPIMVNELA 236
162139369 160 QYNFKLVCLAGALLFLFAAILNAWLLPAYRISNAQTSMLEGIRRVLYDQRFVTYVFTLTGYYILSVQVMLILPIRVNEVA 239
33519909  241 GQLSYIKYIYITEAILSLLLIIPITYWMEKYFKLETRLMLGLVIMIISLSPIGSVNNLYELLILISLFYIGSIVAEPARE 320
145300316 238 GTTTAVGWMYTLETAISLTLLYPLARYGEKHFKLENRLMAGVLLMTTGIGLVAFATTLPAVFVLLACFYLGIVIAEPARE 317
85059223  240 GQPAAVKWMYAIEAALSLSLLYPIARWSEKRFRLETRLMAGLTVMLLSLFPIGLIEDLRALFMLIGLFYIGSIIAEPARE 319
50121449  240 GTPSAVKWMYAIEAVLSLTLLYPIARWSEKRFRLEQRLMVGLFIMSVSMFPIGMTTELRPLLMLISLFYMGSIIAEPARE 319
253688189 240 GTPSAVKWMYAIEAALSLTLLYPIARWSEKRFRLEQRLMAGLFIMSVSMFPIGMTTELQTLLMLICLFYIGSIIAEPARE 319
71892232  240 GQLSYIKWMYIIEAILSLLLIMPITWWSEKYFKLETRLMVGLITMIISLFPIGLVKNLHTLLILISLFYIGSIIAEPARE 319
242239609 240 GTPSAVKWMYAIEAVLSLSLLYPIARWSEKRYRLEQRLMLGLFIMTLSLLPMGMVTHIRLLLLLIGIFYLGSIIAEPARE 319
271500750 240 GSPSAVKWMYAIEAVLSLTLLYPVARWSEKRFRLEQRLMFGLFIMTLSLIPMGMVTSLQWLLGLIALFYIGSIIAEPARE 319
251789876 237 GTPSAVKWMYAIEATLSLTLLYPIARWSEKRFRLEQRLMFGLFIMTLSLIPMGMVTNLQWLLGLIALFYLGSIIAEPARE 316
162139369 240 GQLAAVRWTYAIEAALSLSLLYPIARWSEKRFSLENRFMAGLTIMLLSIIPIGMIHNLQVLFLLIGIFYTGSIIAEPARE 319
33519909  321 TLSALLTNYKARSSYIGFNKLSLALGGTLGYSGGGWLYDLGKELNFYQLPWIALSIIGTITVLILYYQFRYCSIQPSLYT 400
145300316 318 TLMTKLAQPGARGSYMGFSRLGLALGGMTGYVGGGALHDYANAQGQPWLPWLVLGTVGVTTLLLLVNCFHREPSLARVNI 397
85059223  320 TLGASLADNRARGSYMGFSRLGLALGGAIGYSGGGWLYDVGNRLEIPQLPWFMLGLIGFITLLGLYRQFQQRPIEPAMLN 399
50121449  320 TLSASLADSRARGSYMGFSRLGLALGGAIGYSGGGWLFDTGHALNQPELPWFMLGTIGFLTLAALYWQFNQRRIEPAMLG 399
253688189 320 TLSASLADARARGSYMGFSRLGLALGGAIGYSGGGWLFDTGHALNQPELPWFMLGTIGFLTLAALYWQFNQRRIEPAMLG 399
71892232  320 TLGALLTDYKARSSYIGFSKLSLALGGTVGYSGSGWLYDIGKEQNFTQLPWIILSIIGLITLLGLYCQFKYYSFQSLLNN 399
242239609 320 TLSASLSDARARGSYMGFSRMGLALGGALGYSGGGWLFDMGKSLNQPALPWCMLGIVGMLTLAALYWQFHLKRLEPAILR 399
271500750 320 TLGASLADARARGSYMGFSRMGLALGGALGYSGGGWLFDTGKALGQPALPWCMLGIIGMLTLAALYWQFHLRRIEPAMLS 399
251789876 317 TLGASLADARARGSYMGFSRMGLALGGALGYSGGGWLFDTGKALGQPALPWGMLGIIGMLTLAALYWQFHLKRIEPAMLS 396
162139369 320 TLGASLADNRARGSYMGFSRLGLALGGAIGYSGGGWLYDMGNQLDIPQLPWVMLGMIGLITLLGFYRQFHQHHYQTYSXY 399
33519909  401 D 401
145300316     -    
85059223  400 G 400
50121449  400 G 400
253688189 400 G 400
71892232  400 S 400
242239609 400 D 400
271500750 400 E 400
251789876 397 E 397
162139369 400 L 400
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