Conserved Protein Domain Family
DUF4619

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pfam15398: DUF4619 
Domain of unknown function (DUF4619)
This family of proteins is found in eukaryotes. Proteins in this family are typically between 128 and 299 amino acids in length.
Statistics
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PSSM-Id: 464705
Aligned: 11 rows
Threshold Bit Score: 375.713
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003121874   1 MGLSHSKAHQRVTKVAPLQDKEEETPSAGLVDFAFTQNLEEKSSCSFSRLQDRnKALEGQLPPLRETWYGRYSAvlhVPR 80 
XP_016284106   1 MGSKHSKAYPRVTKVAPIQDKCPLSSPVNHREVPFIDNLEKRSLYPFAKLQGQ-KKSPKQLPPLRETENGRYSSdlnMPR 79 
XP_005322940   1 MGRSHSKAHSRVTKVAPLQNKGADTPSAGPMDFAFNHNLEEKSSYSLARLQDRnEILNGQLPPLRETWYGRYST---APR 77 
XP_002718313   1 MGLRHSKSHPRVIKVAPLRNKEEETAPAGPVDFAIKQNLEEKSSCSLPRLQDQnKALEGPLPPLRETWYGRYST---VSQ 77 
Q9CPZ1         1 MGLGHSKAHPRVIKVTPLQSQETETPSTGPVFFALNRNLEEES--SFTRLQDQnRTREGQLPPLRETWYGRLPA---VSR 75  house mouse
XP_510235      1 MGLSHSKTHPRVIKVAPLQNKEVETPSAGRVDFAFNQNLEEKTSYSLARLQDQnKALEGQLPPLQENWYGRYST---ASR 77 
XP_004871149   1 MGLSYAKAHPGVTKVAPFQSKEAETPSAGPLNFAVHQNLEENNLYLFTRLQDQnRALEGQLPPLRENWYGRYSA---APR 77 
XP_003794457   6 MGLSYSKARPRVTKVAPLQNKEEETPLVGPMDFTVNQTLQGKSSPLLARPQDQsKTLEGQLPPLRETRYGRYFA---ASR 82  small-eared galago
XP_003408539   1 MGLGHSKAHPRVTKVAPLQNKGEETPSACPVDFAFSQNLEEKSLYSFSTLQDRtKALEGQLPPLRETWYGRYSA---VPR 77  African savanna...
XP_012403959   1 MGSKYSKSHHKVTRVAPMQDKDLMSSPASPVDIIFNENPEEQSLYSFARKQEK-KTLDRQLPPLRETLYGRYSSgleISR 79  Tasmanian devil
XP_001516682   1 ---mgsgssrthpkvtqvaplysrdapppsvgsaaggqeegyssrtsaglrgkmgqferqlpplrqtgygcyaT---VPG 74  platypus
XP_003121874  81 AMYFDIPLEQGETSIIKRHPPRRFQKLEPIDlPQVMTSERLLSQQEAARTQKAKQELEKNMQIPTYPSGKRQYLHKMQML 160
XP_016284106  80 PMSFDISVEKRETSIIKKHPPRRFQIFEPFG-PEITNAEKFLTHKGAETTPKKKQDLEKKMQSLTYSSGKRQYLNKMKML 158
XP_005322940  78 AMYFDIPLERGETSIIKRHPPRRLEKLEPIDlPQVITSERLLSQQQTWTRHKAKQKLEKKMQTPTYTSGKRQYLHKMQML 157
XP_002718313  78 AMYFDIPLEQGETSIIKRHPPRRPQKLEPIDlPQVITSERLLSQREARTRHTAKQELEKKMQAPTYASGKRQYLHKMQML 157
Q9CPZ1        76 AMYLDIPLKHEETSIIKRHPPRRIQKLEPIDlPQAITSERLLCHQEGRTKSNTKQENEKKIQLPMYTSGKRQYLHKMKML 155 house mouse
XP_510235     78 DMYFDIPLEHRETSIIKRHPPQRLQKLEPIDlPRVITSGRLLSQREARTMHKAKQVLEKKMQTPMYTSENRQYLHKMQML 157
XP_004871149  78 DMYFDIPLEPGETSIIKRHPPQRLQKLQPIDlPQVRTSERLPSQQAARMRPRAKQELEKKMQTPMYTSGKRQYLHKMQML 157
XP_003794457  83 TMYFDIPLEQGETSIIKRHPPQRLQKLEPMDlPQVITSKRLQSQREAGMVHRAQ-ELEKKMQTPMYTSGKRQYLHKMKML 161 small-eared galago
XP_003408539  78 AMYFDIPLEKRETSIIKRHPPRRLQKLEPIDlPQVITSERLLSQQEARTTHKAK-------------------------- 131 African savanna...
XP_012403959  80 PMSVDIPLERGETSIIKRHPPRRFQMLEPLE-PQVNTAEKFLTQKAAETMLKKK-ELEKRMQALTYSSGKRQYLHKMKML 157 Tasmanian devil
XP_001516682  75 AMTLDTSLENRGTSIIKSHPPRRLQVLEPVGpPQ---ARGSLTQHEAAVAPRAK-ELEKRMQSVRHPLGKRQYFHKMQML 150 platypus
XP_003121874 161 EMNRKRQEVQVELKKSLHKEAKI-NKqrqrdHKTKKILQSIPRNDD-GDSLISLPDETLNRSPGNSQNAEFLEHQPRNDY 238
XP_016284106 159 EMNCKKQEAQAELKRNLHKDARI-NK-----HKAKKILENMQKNDSrKNSMTRKSDVLMNGNKGNEQNREFAKNHEQIEY 232
XP_005322940 158 EMNRRRQEIQMELKKSLHREERVtNKqnlrdHKVKKILQSIPGNED-DDLLTTLPDETMNRGPGNSQAAEFLDYQARNEY 236
XP_002718313 158 EMNRKRQETQMELKKSLHKEARI-SNqklrdHKAEKILQSVSMDGD-YDLLTTLPEKILNRRLGNIENAEFLKHQARNDY 235
Q9CPZ1       156 EMNHKRQEAQMELRKSLLSKAML-DMqklkdHNGNKIAQSKPRSNG-YDILTILPNENINRDPGNPQDEEFLDCHTENDY 233 house mouse
XP_510235    158 EMIRKRQEAQMELKKSLHGEARI-NKqspsdHKAKKTLQSTPRNDD-YDLLTMLPDEILNRGPGNSKNTEFLKHQAVNNY 235
XP_004871149 158 EMNRKRQEAQMELKKSLHREAKI-NEqkprdHKAKKTLQSVPRNDD-YDIVTMLPEETMNRGPGNSQDAEFLQYQARNYY 235
XP_003794457 162 EMNRKRQEAQMELKKTLPKEMRI-NKqnlrdHKAKKILEGIPRNND-HDLLTMLLNETLTRNPGNSQNAEFLEHHTVNDH 239 small-eared galago
XP_003408539 132 --------AQMELKKNLHREARI-NKqklreHKAKKILQS-PRDED-HDLLTWLPDETENRSPGNSWNAELLGHQAGNDY 200 African savanna...
XP_012403959 158 EMNCKKQEsqNELKRSLHREARI-NKhkmneLKAKKVLENMPRDDDnEDFVAMESNIPINEERGNAWNKELM-NHEWSGY 235 Tasmanian devil
XP_001516682 151 EMNRKRQEAQAELKRNLQRESRI-GKqkareRRGKKPSVNLPGNRGwEDLATPEPPGALPADWGSPWDGEFGACQPG--- 226 platypus
XP_003121874 239 CPRKTGKMETWLHEQEARGQLLWDSSSSDSDELGKFEKKPRALVRTRTERIPLFDEFFDRE 299
XP_016284106 233 NPRRSDVLRRWSLKQQVQDEIFWDSSSTSSDDLDKNERKSWGLLRTKTQRIPVFDELLDQE 293
XP_005322940 237 CHRKIGKMEAWLREQEARGQILWDISSSDSDEQGNDDKKPRALVRTRTERIPLFDEFFDGE 297
XP_002718313 236 RTRKIGKMEKWIREQEARGQLFWDSSSCDSDEMGTDEKKPQALVRTRTERIPLFDEFFDQE 296
Q9CPZ1       234 YVRKIGKMETWLREQEARGQLFWDSSSSDSDELEKDERRPQALVRTKTEKIPLYDDFYD-S 293 house mouse
XP_510235    236 CPWKIGKMETWLHEQEAQGQLLWDSSSSDSDEQGKDEKKPRALVRTRTERIPLFDEFFDQE 296
XP_004871149 236 CPWKMGKMETWFHEQEARGQLLWDSSSSDS-ELGRDEKKPQPLVRTRTERIPLFDEFLDQE 295
XP_003794457 240 CPQKVGKMETWLCEQEARGQLSWNGSSSDSDELGTDEKRPRALVRTRTERIPRYDAFFDQE 300 small-eared galago
XP_003408539 201 CPRKIGKIETWLREQETQGQLFWDGSSSDSDESGKNEKKPRALVRTRTERIPLFDEFFDQE 261 African savanna elephant
XP_012403959 236 HPRKSDELRRWSLKQQVQDELFWDSSSTNSDESEKDERKCWTLVRTKTERIPVFDEFFDQE 296 Tasmanian devil
XP_001516682 227 -PRQGGEAEPRLVRR-AHRELPWETADSDSDGEAEERKKPRALVRTKTERIPLWDEFFDQE 285 platypus
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