Conserved Protein Domain Family
ARMH3_C

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pfam08427: ARMH3_C 
Armadillo-like helical domain-containing protein 3, C-terminal
This is the C-terminal domain of Armadillo-like helical domain- containing protein 3 (ARMH3), the previously uncharacterized peripheral Golgi protein C10orf76. ARMH3 interacts with and is involved in GBF1 recruitment, Golgi maintenance and protein secretion. The function of this domain is unknown.
Statistics
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PSSM-Id: 462473
Aligned: 63 rows
Threshold Bit Score: 213.581
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_010757008  406 RILATVIFDIMIDTINHNL-RRGLDVNLYCHTISILLRLLTYVSSNKTRLTYHWSELWRTLATLTRFLAT----YSTDLL 480 
CDS35750      461 NTMAAVLLDLLVEFFCTHL-MKSFPFEIHGQCLNICYHLLSHQKEHGLRLNYDWRQLWKALFDLMRYVIK----PDGPCV 535 
XP_001952575  430 KPLAAALLDLMIEFMLGHM-MKKLPLDQYMKCISIIHRIICYQKRNSVRLCYNWKDLWSSLITLLKFLMT----YEHQLS 504 
XP_002070278  429 QPLAATLLDLLVEFIVSHL-MKKFPMELYLLCIGVIHRILCYQKRCRVRLNYPWKELWSALIGLLRFLVN----QEQTLV 503 
XP_008210355  417 QPLAATLLDLIVEFIMSHM-MKKFPLELYHHCIGILLRILCYQKRCRVRLNYQWIHLWTVLMNLLKFITT----HESSLA 491 
EFN83594      423 QPLAATLLDLLVEFITSHM-MKKFPLELYHQCIGVLQRLLCYQKRCRVRLGYQWRDLWTALINLLKFLTT----HESHLI 497 
EDQ91406       95 GAMAKMIFDVAIELLMSHM-KKSLNVEQFGLTLQIIHRLLCFEKHSRVRLNFKWQQLWNALAALLRFIVA----HASTLE 169 
EFC48169      457 GTLAKVLMELLIDFIFHHLqRKHFPVDLAMRALSAIHLLICQSRKYRVRFAVDWDTLWKALTMICDIIAKdncsKDKEKA 536 
EGG17293      583 HPITTYVINILNQFMKCNL-KAK-NGDIQHKIISCIQRVVSYKKKTQARLPIKWNETWLSLFSFITSIMT----SEKNLL 656 
Q551U4        728 HPLSCWTLDILSQFIKCNL-KGKISMDVHQSAVDCIHRIVSYKKKTLNRLPYKWSELWSALFSLISMVSTlnisNDKIQL 806  Dictyostelium...
XP_010757008  481 SNPQTHNLAASLIDLIVFCISAGDTFLPDPASYDDLFYKVVETGPiltRFKEIYKPSfspsaptstppktt--------- 551 
CDS35750      536 C-GETFTTLLKIVGIFNFFITFGDCFLPDPNTYDDLYYELIRMKD---VVERLIKFVdqhscspk--------------- 596 
XP_001952575  505 QDMNIYDLGIQIVNIFNLFITYGDMLLPSPSSYDELYYEIIRMHT---VFDNIYVLSsrnsssv---------------- 565 
XP_002070278  504 KKCNIFHLSLQVVNIFNLFITYGDTFLATTNSYDELYYELNREEK---VFTEIHAMVlryttmpe--------------- 565 
XP_008210355  492 KKMNIFSLATKVVNILNIFITYGDMFLLSPNTYDELFYEIIRMKF---IFINLNAMGlrysnndt--------------- 553 
EFN83594      498 KKMNIFPLAIQVVNILNLFITYGDTFLSSPSSYDELFYEIIRMRL---IFTNLNAMAlrystses--------------- 559 
EDQ91406      170 EQFDVYDLARQVVVIYNLFVTYGDTFLPDPDSYDQLYYELIRERN---AFDTLFELAkrhsrta---------------- 230 
EFC48169      537 S-----QLLEKVLKLFNLGILKGEAFLPTRKHHEQMIYHFVRQSA---VFDELLDWMernl------------------- 589 
EGG17293      657 S--DLIPIGIEAINLFNLFINYGDLFLPQPSDYDDLFYELIRGSK---VIEEFSKLVeve-------------------- 711 
Q551U4        807 N--QSIHVGISTVNIFNLFINYGDSFLPSPNDYDELFYEIIRSGQ---VIENFYQFIlnqtttggqsvtspsaaasasnp 881  Dictyostelium...
XP_010757008  552 --------------gakvpsiptptptpSSAALSIDTLISVASHFHSLLfldDTDKKTSpapttttpttttdpaaaaeil 617 
CDS35750      597 ---------------------sdwkssaRDLRESAQNLKVIVKHFNDKI---SAYIAKS--------------------- 631 
XP_001952575  566 ---------------------sehklsaTKLSNCLINIRAIINHYIPKI---DNWLEKN--------------------- 600 
XP_002070278  566 ---------------------ceykddvIKLLNALVNILAIVKHFQNKI---KEWLAEQ--------------------- 600 
XP_008210355  554 ---------------------yeykesaAKLINALVNMRDILNHFPPKI---SEWLSKE--------------------- 588 
EFN83594      560 ---------------------yehkehaLKLTNSLVNVRDIVNHFPPKI---TAWLTKE--------------------- 594 
EDQ91406      231 ---------------------gtyataaGRLATSLINIRAIIGHFAPKI---DAWSQLH--------------------- 265 
EFC48169      590 -------------------------kkvNTNRQLLTNVSMIISEIGEEI---YSK------------------------- 616 
EGG17293      712 -------------------------dptGNMTNSLLNIKSIIAHFSTHI---QTWNNEH--------------------- 742 
Q551U4        882 ttptplspqqlptittttttitsnnesnNPLLNQLLNIRSIVQHFTSKL---EEWSANN--------------------- 937  Dictyostelium...
XP_010757008  618 tmgKKKNLSPREVHQIIKQGYDTLSIRS-QEGLNLWEKWRESD--W----KSELKRIARCAVEDARV 677 
CDS35750      632 ---SITSLTEAQVFEIIQNNYESLTLRv-SKDLNKY--YDEAAgdV----EEDNDRMLVEVVQNVRR 688 
XP_001952575  601 ---SVTTPVGEEILEVVRNNYDTLTLKLlLDCLGSFE---SNKsnHdlssSSLIKLMVSKVVKDTRQ 661 
XP_002070278  601 ---GLSTPTEDQILDVVRKNYD-LTLKl-QDSLDQYERY-AEAplH----TNFFKTMVRDVVNDTRK 657 
XP_008210355  589 ---NISTPTEKQIMDIIIQNYDSLTLKl-QDNLDQFDRY-SENtsH----LKFFDSLVKSIIYTTRT 646 
EFN83594      595 ---SLSTPTEQQILAIIIQNYDSLTLKl-QDNLDQYERY-SEKpnH----TAFFEEMVSGVVVDTRA 652 
EDQ91406      266 ---SGAPPSPENVLTVVRENYDTLTLKl-QDGLDTYAPY-HEApeA----QKRLVQICRSMLHHqpt 323 
EFC48169      617 ---YGNYPSEDQVFTIIRESYPKLKLNDfQ-TLEEVDEY-VENpnE----VTFFSQLLRVFIFDCKQ 674 
EGG17293      743 ---PEEPLTSDMVIAIIKDNYETLRLKl-AENLDVYEKY-VENsnE----AVFYRHYIRFLILDTKK 800 
Q551U4        938 ---AEVALTAPQVSKIIKDNYDTLRLKl-QENLDQFEPY-VENpkE----VLFFKHIIKELINDLRK 995  Dictyostelium discoideum AX4
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