Conserved Protein Domain Family
PLN02475

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PLN02475: PLN02475 
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
Statistics
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PSSM-Id: 215264
Aligned: 27 rows
Threshold Bit Score: 1143.36
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
115489652   1 MASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMADAGIKYIPSNTFSYYDQVLDTAAMLGAVPE 80 
168064677   1 MTSHVVGYPRMGPKRELKFALESMWDGKTQAADLEQVAKDLRASIWKQMSEAGVSMIPSNTFSYYDQVLDTTAMVGAVPA 80 
168011673   1 MASHVVGYPRMGPKRELKFALESMWDGKTQAADLEQVAKDLRASIWKQMSEAGVSMIPSNTFSYYDQVLDTTAMVGAVPS 80 
168009345   1 MASHVVGYPRMGPKRELKFALESMWDGKTQAADLEQVAKDLRASIWKQMAEAGVSMIPSNTFSYYDQVLDTTAMVGAVPA 80 
159489910   5 LSTTTIGFPRIGNQRQLKFAMESYFKGDSGEAELLAVAHKVQSDAWALQKAAGIAVIGLDG-TLYDQVLDTITWLGAIPP 83 
145334531  49 MSSHIVGYPRIGPKRELKFALESFWDGKTNVDDLQNVAANLRKSIWKHMAHAGIKYIPSNTFSYYDQMLDTTAMLGAVPS 128
30688090   49 MSSHIVGYPRIGPKRELKFALESFWDGKTNVDDLQNVAANLRKSIWKHMAHAGIKYIPSNTFSYYDQMLDTTAMLGAVPS 128
225436073   1 MASHIVGYPRMGPKRELKFALESFWDGKSSAEDLQKVAAELRASIWKQMADAGIKYIPSNTFSYYDQVLDTTAMLGAVPE 80 
297812285  47 MSSHIVGYPRIGPKRELKFALESFWDGKTSVDDLQNVAANVRKSIWKHMADTGIKYIPSNTFSYYDQMLDTTAMLGAVPS 126
302772695   1 MASHIAGYPRMGPKRELKFALESFWDGKSSAADLEKTAKDLRASIWKQMSDAGVSFIPSNTFSYYDQVLDTTAMVGAVPP 80 
115489652  81 RYSWTGGEIGFSTYFSMARGNATVPAMEMTKWFDTNYHFIVPELGPNT-----------KFSYSSHKAVNEYKEAKALGV 149
168064677  81 RYGWTGGEIGHDVYFSMARGNKTKPAMEMTKWFDTNYHYIVPELSGET-----------KFVYSSRKAVSEYKEAKELGV 149
168011673  81 RYEWTGGEIGHDVYFSMARGNKTKPAMEMTKWFDTNYHYIVPELSGET-----------KFVYSSRKAVSEYNEAKALGI 149
168009345  81 RYEWTGGEIGHDVYFSMARGNKTKPAMEMTKWFDTNYHYIVPELSSET-----------KFMYSSRKAVSEYKEAKALGV 149
159489910  84 RFKHLSG---LQRYYAMARGGA---ALDMSKFFDTNYHYLVPELGPDVlgpataagaplQPDFSGPLDKLARGQAVVGRE 157
145334531 129 RYGWESGEIGFDVYFSMARGNASAHAMEMTKWFDTNYHYIVPELGPDV-----------NFSYASHKAVVEFKEAKALGI 197
30688090  129 RYGWESGEIGFDVYFSMARGNASAHAMEMTKWFDTNYHYIVPELGPDV-----------NFSYASHKAVVEFKEAKALGI 197
225436073  81 RYGWNGGEIGFDAYFSMARGNASVTAMEMTKWFDTNYHFIVPELGPNV-----------KFSYASHKAVNEFKEAKALGI 149
297812285 127 RYGWESGEIGFDIYFSMARGNASAHAMEMTKWFDTNYHYIVPELGPNV-----------KFSYASHKAVVEFKEAKALGI 195
302772695  81 RYGWTGGDVAFDTYFSMARGNAKQPAMEMTKWFDTNYHYIVPELGPEV-----------KFTLSSRKVLEEYTEAKELGI 149
115489652 150 DTVPVLVGPVSYLLLSKPAKGVEKSFALLSLLSSILPVYKEVIAELKAAGATWIQFDEPTLVLDLDSHQLAAFSAAYTEL 229
168064677 150 DTVPVLIGPVTYLLLSKGDKSAPKGFNTLSLLDAILPVYKEVITELKEAGASWIQLDEPKLVMDLEASQYEAFKKAYAVL 229
168011673 150 DTVPVLVGPVTYLLLSKGDKSAPKGFNTLSLLDAILPVYKEAITELKGAGASWIQLDEPKLVMDLESAQYEAFKKAYAVL 229
168009345 150 DTVPVLVGPVTYLLLSKGDKSAPKGFDTLSLLDAILPVYKEVITELKEAGASWIQLDEPKLVMDLEAAQYEAFKKAYAVL 229
159489910 158 RAVPILIGPVTFVSLSRGCE-----LPLDQAVARLLPTYCALLQQLAAAGAPEVQLHEPVLATSEGAGMRAEFETAYAQM 232
145334531 198 DTVPVLIGPMTYLLLSKPAKGVEKSFCLLSLIDKILPVYKEVLADLKSAGARWIQFDEPILVMDLDTSQLQAFSDAYSHM 277
30688090  198 DTVPVLIGPMTYLLLSKPAKGVEKSFCLLSLIDKILPVYKEVLADLKSAGARWIQFDEPILVMDLDTSQLQAFSDAYSHM 277
225436073 150 ETVPVIVGPVSYLLLSKPAKGLEKSFSLLSLIDKILPIYKEVVTELKKAGATWIQFDEPTLVLDLDSHHLQAFTHAYSEL 229
297812285 196 DSVPVLIGPMTYLLLSKPAKGVDKSFCLLSLIDRILPVYKEVLADLKSAGARWIQFDEPILVMDLDTSQLQAFSDAYSYM 275
302772695 150 ETVPVLVGPFTYLSLAKPAKGVAKDFDLLGLLEDLLPVYKEVIGELKSAGAKWIQFDEPALVLDLESHKYDVFKKAYSDL 229
115489652 230 eSALSGLNVLIETYFADIPAESYKTLTSLNsVTAYGFDLIR------GAKTLDLIKSAGFPSGKYLFAGVVDGRNIWADD 303
168064677 230 -GEVAQVKLLVETYFTDLPAEAYKTLCDLP-IAGFGVDLVR------GNKTLSLIKEHGLPEGKTLFAGVVDGRNIWAND 301
168011673 230 -SEVSGVKLLVETYFTDLPVEAYKTLCDLP-IAGFGVDLVR------GSKTLAVIKEHALPTGKTLFAGVVDGRNIWAND 301
168009345 230 -GELSGVKLLLETYFTDLPAEAYKTLCGLP-ISGFGVDLVR------GSKTLSIIHEQGLPAGKTLFAGVVDGRNIWAND 301
159489910 233 aQAAGSVPLHLVTYYDDLGA-AYPWAVQLP-VAAVTLDFLGppgaavPSQTLALLQQHGFPADKRLGAGVVDGRSVWKDD 310
145334531 278 eSSLAGLNVLIATYFADVPAEAYKTLMSLKcVTGFGFDLVR------GLETLDLIK-MNFPRGKLLFAGVVDGRNIWAND 350
30688090  278 eSSLAGLNVLIATYFADVPAEAYKTLMSLKcVTGFGFDLVR------GLETLDLIK-MNFPRGKLLFAGVVDGRNIWAND 350
225436073 230 eSTVSGLNVLIETYFADVPAEAYKTLTSLKgVTGFGFDLVR------GTKTLDLIH-SGFPSGKQLFAGVVDGRNIWAND 302
297812285 276 eSSLAGLNVLIATYFADVPAESYKTLMSLKcVTGFGFDLVR------GLETLDLIK-MNFPRGKLLFAGVVDGRNIWAND 348
302772695 230 aPSFGDLKLLVVTYFADLPAPAYELLTGLEcVDGVGLDLVR------GTKTVELIKVAGFPSSKKLFAGVVDGRNIWAND 303
115489652 304 LAASLTTLESLE--AIVGKDKLVVSTSCSLMHTAVDL----------VNETKLDSEIKSWLAFAAQKVVEVNALAKALAG 371
168064677 302 LAASVAVVEELQ--AKLGKDNVVVSTSCSLLHSAVDL----------KNETKLDSELKSWMAFAAQKLLEVVAVAKAVSG 369
168011673 302 LAASVNTVKELQ--ASLGKDNVVVSTSCSLLHSAVDL----------KNETKLDNELKSWMAFAAQKLVEVVAIANAVSG 369
168009345 302 LAASVAVVEELQ--AKLGKENVVVSTSCSLLHSAVDL----------KNETKLDSELKSWMAFAAQKLLEVVAIAKAVSG 369
159489910 311 -GTAVALLRALLdtGAVSSDRLVVTSSAPLQHLPYDLgleleapktpEAEPHLPPALAARLGFAKQKVEEIVSVARLAAS 389
145334531 351 LSASLKTLQTLE--DIVGKEKVVVSTSCSLLHTAVDL----------VNEMKLDKELKSWLAFAAQKVVEVNALAKSFSG 418
30688090  351 LSASLKTLQTLE--DIVGKEKVVVSTSCSLLHTAVDL----------VNEMKLDKELKSWLAFAAQKVVEVNALAKSFSG 418
225436073 303 LAASLNTLKSLE--DKVGKGNLVVSTSCSLLHTAVDL----------ANETKLDKEIKSWLAFAAQKVHEVNALAKALSG 370
297812285 349 LSASLKTLQTLE--DIVGKEKVVVSTSCSLLHTAVDL----------VNEIKLDKELKSWLAFAAQKVVEVNALAKSFSG 416
302772695 304 LASSLTLLGELE--SKLGKGNVVVSTSSSLLHTAVDL----------KNETKLDAELKSWLAFAAQKIVEVVSLAGALGG 371
115489652 372 QKDEAYFAANAAAQASRRSSPRVTNEEVQKAAAALKGSDHRRATNVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVR 451
168064677 370 QKDEAFFAANASAQESRRNSPRVHNKAVKEAAAALAGSEHRRSTPVSSRLEQQQKYLNLPILPTTTIGSFPQTPELRRVR 449
168011673 370 NKDEEYFAANAAAQASRRNSPRVHNKAVKELAAGLAGSEHRRATPVSTRLEEQQKYLNLPILPTTTIGSFPQTPELRRVR 449
168009345 370 EKDEEFFSANAAAQASRRNSPRVHNKAVKELAASLAGSEHRRATPVSSRLDQQQKHLNLPILPTTTIGSFPQTPELRRVR 449
159489910 390 PAAAAAAAGHGAVVQLQRLQ---QGKGVEDHTADIPAEWFSRPKPYDVR---REQQLQLPAFPTTTIGSFPQTAEVRRLR 463
145334531 419 AKDEALFSSNSMRQASRRSSPRVTNAAVQQDVDAVKKSDHHRSTEVSVRLQAQQKKLNLPALPTTTIGSFPQTTDLRRIR 498
30688090  419 AKDEALFSSNSMRQASRRSSPRVTNAAVQQDVDAVKKSDHHRSTEVSVRLQAQQKKLNLPALPTTTIGSFPQTTDLRRIR 498
225436073 371 QRDEAFFFSNAAAHSSRKFSPRVTNENVQKAAASLKGSDHRRATDVSARLDAQQKKLGLPVLPTTTIGSFPQTMDLRRVR 450
297812285 417 AKDEALFSSNSMRQASRRSSPRVTNAAVQQDVAALKKSDHHRSTEVSVRLQAQQKKLNLPALPTTTIGSFPQTTDLRRIR 496
302772695 372 KKDEEFFAANASAQASRKTSPRVHNDEVKKAAAALQGSEHRRATPVADRLDEQQKHLKLPILPTTTIGSFPQTADLRRVR 451
115489652 452 REYKAKKISEEEYISAIKEEISKVVKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPIIYG 531
168064677 450 REVKSKKISEEDYDKAIKAEIDSVVKLQEELDIDVLVHGEPERNDMVEYFGEQLDGFCFSANGWVQSYGSRCVKPPIIFG 529
168011673 450 REVKSKKISEEDYDKAIKAEIDSVVKLQEELDIDVLVHGEPERNDMVEYFGEQLDGFCFSANGWVQSYGSRCVKPPIIFG 529
168009345 450 REVKSKKISEEDYDKAIKAEIDSVVKLQEELDIDVLVHGEPERNDMVEYFGEQLDGFCFSANGWVQSYGSRCVKPPIIFG 529
159489910 464 QQLKSGRLTQAEYEGLIAGHIAHAVGVQEALGIDVLVHGEAERTDMVEYFGMQLGGMLFTRAGWVQSYGSRCVRPPLVVD 543
145334531 499 REFKAKKISEVDYVQTIKEEYEKVIKLQEELGIDVLVHGEAERNDMVEFFGEQLSGFAFTSNGWVQSYGSRCVKPPIIYG 578
30688090  499 REFKAKKISEVDYVQTIKEEYEKVIKLQEELGIDVLVHGEAERNDMVEFFGEQLSGFAFTSNGWVQSYGSRCVKPPIIYG 578
225436073 451 REFKAKKISEDDYVKAIKDEINKVVVLQEELDIDVLVHGEPERNDMVEYFGEQLSGFAFTVNGWVQSYGSRCVKPPIIYG 530
297812285 497 REFKAKKISEVDYVQTIKEEYEKVVKLQEELGIDVLVHGEAERNDMVEFFGEQLSGFAFTSNGWVQSYGSRCVKPPIIYG 576
302772695 452 RDVKSKKISEEEYVTAIKSEIASVVKLQEELDIDVLVHGEPERNDMVEYFGEQLQGFAFTVNGWVQSYGSRCVKPPIIYG 531
115489652 532 DVSRPNPMTVFWSKLAQSMTSRPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQVIQIDEAALR 611
168064677 530 DVSRPKAMTVYWSTYAQSVTKRPIKGMLTGPVTILNWSFVRNDQPRSETCYQISLAIKDEVEDLEKANITVIQIDEAALR 609
168011673 530 DVSRPKAMTVYWSSYAQSVTKRPMKGMLTGPVTILNWSFVRNDQPRSETCYQISLAIKDEVEDLEKANITVIQIDEAALR 609
168009345 530 DVSRPKAMTVYWSTYAQSVTKRPMKGMLTGPVTILNWSFVRNDQPRSETCYQISLAIKDEVEDLEKANITVIQIDEAALR 609
159489910 544 DITYRGPMTCWEYKVASAYTRKPVKGMLTGPVTILNWSFPRKDISRAAQAMQLGLALRQEVAALEAAGCTIIQVDDPALR 623
145334531 579 DITRPKAMTVFWSSMAQKMTQRPMKGMLTGPVTILNWSFVRNDQPRHETCFQIALAIKDEVEDLEKAGVTVIQIDEAALR 658
30688090  579 DITRPKAMTVFWSSMAQKMTQRPMKGMLTGPVTILNWSFVRNDQPRHETCFQIALAIKDEVEDLEKAGVTVIQIDEAALR 658
225436073 531 DVSRPKAMTVFWSSMAQSMTKRPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKDEVEDLERAGITVIQIDEAALR 610
297812285 577 DITRPKAMTVFWSSMAQKMTQHPMKGMLTGPVTILNWSFVRNDQPRHETCFQIALAIKDEVEDLEKAGVTVIQIDEAALR 656
302772695 532 DVSRPKAMTVEWSSYSQSLTKRPMKGMLTGPVTILNWSFVRNDQPREKTTYQIALSIKEEVEDLEKAGIHVIQIDEAALR 611
115489652 612 EGLPLRKAEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIHSIINMDADVITIENSRSDEKLLSVFREGVKYG 691
168064677 610 EGLPLRKSEHADYLRWAVHGFRITTCGVKDTTQIHTHMCYSNFNDIIHSIIDMDADVITIENSRSDEKLLSVFREGVHYG 689
168011673 610 EGLPLRKSEHADYLRWAVHGFRITTCGVKDTTQIHTHMCYSNFNDIIHSIIDMDADVITIENSRSDEKLLSVFREGVHYG 689
168009345 610 EGLPLRKSEHADYLRWAVHGFRITTCGVKDTTQIHTHMCYSNFNDIIHSIIDMDADVITIENSRSDEKLLSVFREGVHYG 689
159489910 624 EGLPLKRERWASYLSWAVDAFRLCTGVAAAGTQVVTHLCYSDFQDILPAIDRMDADVLTIENSRSDNAMMAAL-AAAGYG 702
145334531 659 EGLPLRKSEQKFYLDWAVHAFRITNSGVQDSTQIHTHMCYSNFNDIIHSIIDMDADVITIENSRSDEKLLSVFHEGVKYG 738
30688090  659 EGLPLRKSEQKFYLDWAVHAFRITNSGVQDSTQIHTHMCYSNFNDIIHSIIDMDADVITIENSRSDEKLLSVFHEGVKYG 738
225436073 611 EGLPLRKSEQAFYLEWAVHSFRITNCSVQDTTQIHTHMCYSNFNDIIHSIIDMDADVITIENSRSDEKLLSVFREGVKYG 690
297812285 657 EGLPLRKSEQKFYLDWAVHAFRITNCGVQDTTQIHTHMCYSNFNDIIHSIIDMDADVITIENSRSDEKLLSVFHEGVKYG 736
302772695 612 EGLPLRKSEQAAYLNWAVHGFRITSCGVKDTTQIHTHMCYSHFNDIITAIIDMDADVITIENSRSDEKLLSVFREGVTYG 691
115489652 692 AGIGPGVYDIHSPRIPSTEEIADRVNKMLAVLDTNIL-------WVNPDCGLKTRKYNEVKPALTNMVSAAKLIRTQLAS 764
168064677 690 AGIGPGVYDIHSPRIPPTEEMADRARKMLAVLESKVL-------WINPDCGLKTRKYAEVVPALTNMVNAAKQLRAELAN 762
168011673 690 AGIGPGVYDIHSPRIPPTEEMADRARKMLAVLESKVL-------WINPDCGLKTRKYGEVVPALTNMVNAAKQLRAELAK 762
168009345 690 AGIGPGVYDIHSPRIPPTEEMADRARKMLAVLESKVL-------WINPDCGLKTRKYGEVVPALTNMVNAAKQLRAELAK 762
159489910 703 RDIGPGVYDVHSPVVPSVEFIKSRIRSF---VDSGILsgrydriWVNPDCGLKTRGWPETIAALRNMVEAAAQARAELQL 779
145334531 739 AGIGPGVYDIHSPRIPSTEEIAERINKMLAVLDSKVL-------WVNPDCGLKTRNYSEVKSALSNMVAAAKLIRSQLNK 811
30688090  739 AGIGPGVYDIHSPRIPSTEEIAERINKMLAVLDSKVL-------WVNPDCGLKTRNYSEVKSALSNMVAAAKLIRSQLNK 811
225436073 691 AGIGPGVYDIHSPRIPSTEEIADRINKMLAVLETNIL-------WVNPDCGLKTRKYTEVKPALSNMVAAAKLLRTQLAR 763
297812285 737 AGIGPGVYDIHSPRIPSTEEMAERINKMLAVLDSKVL-------WVNPDCGLKTRNYSEVKSALSNMVAAAKLIRSQLNK 809
302772695 692 AGIGPGVYDIHSPRIPDTEEMAERIRKMLAVLESKVL-------WVNPDCGLKTRKYGEVLPALTNMVKAAKILRAELAS 764
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