1RQ0,2IHR


Conserved Protein Domain Family
RF-1
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pfam00472: RF-1 (this model, PSSM-Id:395378 is obsolete and has been replaced by 459823)
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RF-1 domain
This domain is found in peptide chain release factors such as RF-1 and RF-2, and a number of smaller proteins of unknown function. This domain contains the peptidyl-tRNA hydrolase activity. The domain contains a highly conserved motif GGQ, where the glutamine is thought to coordinate the water that mediates the hydrolysis.
Links
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Statistics
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PSSM-Id: 395378
Aligned: 850 rows
Threshold Bit Score: 51.2856
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1RQ0_A         189 KD--IEIRPEDLKI-ETFR-ASGHGGQYVNKTESAVRI---THl-PT----------------------GI-VVSCQNER 237 Thermotoga ma...
BAM05053       228 GK--LEIDENELEVtAFAR-SSGPGGQNVNKVASAVRI---VHk-PT----------------------Qi-MVVCSVHR 277 Phycisphaera ...
tigr:AHA_0648    4 ISnsVTLPWHELQF-QTMR-AQGNGGQHVNKTDSAVWLrfdYR--NSpsltplykegl-dklsdsrvhdGFiMIRVETHR 78  Aeromonas hyd...
IBRC:GU3_15290   4 VSarVQIPEQELEF-ITMR-AGGPGGQHVNKTDSAVQLrfdYA--GSpslpehykealakmrdhrvlasGLiLIRVESER 79  Oceanimonas s...
jgi:Desal_0067   4 IThtLSIPENEITF-LTSR-SSGPGGQHVNKTSSKVTLvfnVQdsPSlsdyqktlim--srlsgrintkGElQLSCEEHR 79  Desulfovibrio...
XP_003176225    47 PT----IDDSEITG-TYLK-GSGPGGQKINKTSSAVQL---IHi-PT----------------------Nt-VVKCQATR 93  Nannizzia gyp...
XP_007581511    44 PA----INEDDITE-SFLK-GSGPGGQKINKTSSAVQL---KHl-PT----------------------Gi-VVKYQGTR 90  Neofusicoccum...
XP_006685439    37 WL----IKEEDIEE-SFIKgGSGPGGQKINKTNSKVQL---KHi-PT----------------------Gi-VVTSQHSR 84  Yamadazyma te...
EDK43701        30 WL----INEDELEE-KFLHgGSGPGGQKINKTNSKVQL---THk-PT----------------------Gi-VVSCQESR 77  Lodderomyces ...
Q6BMW5          36 WL----IVEEEIDE-AFLKgGRGPGGQKINKSNSKVQL---THk-PT----------------------Gl-VVTCQYSR 83  Debaryomyces ...

1RQ0_A         238 SQYQNKQTALRILRARL----YQLQKEQKEREISQKR-KSqigt---gerSEK-----IRTYNF-PQNRVTDHR 297 Thermotoga maritima
BAM05053       278 KQEQNRKQALGILRAKLelieEEKRQAEMDDatg--------------gkVDRgwgtqIRSYVF-YDNRVKDHR 336 Phycisphaera mikure...
tigr:AHA_0648   79 SQDMNRKEAMNRLVELL----KKaa-----wRPKARHaTKpt------rsSQR-----KRVDAKkRKGEIKSTR 132 Aeromonas hydrophil...
IBRC:GU3_15290  80 SQLMNKEAAKAALVALL----QQag-----kPVKVRRpTKps------kaAKA-----KRADSKtHRGKIKSGR 133 Oceanimonas sp. GK1
jgi:Desal_0067  80 SQFRNKEEVVSRFTKML----AEal-----kPVRKRRkTKvp------ysAKR-----KRLDNKkKRSEVKKGR 133 Desulfovibrio salex...
XP_003176225    94 SQSQNRKIAKRILAEKI-------ELLEKGEQSRAAIvNNvkkkrkaskmKKS-----KRKYRAlEEEKRKK-R 154 Nannizzia gypsea CB...
XP_007581511    91 SRTQNRKTARRMLAERL-------EEIEKGPESRTQLkRAvqakkkassaKKS-----KRKYRAlEEA--KKAA 150 Neofusicoccum parvu...
XP_006685439    85 SQEQNRQKAREILAEKL-------DLMENGPKSRVAVvTErkvklkqskqKKS-----HRKYRKiEEGRAKEKE 146 Yamadazyma tenuis A...
EDK43701        78 SQDQNRKKAREILALKL-------EDIQNPQGSRNTIlKEraqtvkanrmKKA-----NRKYRAlDEERSKQKA 139 Lodderomyces elongi...
Q6BMW5          84 SQEQNRKRAREILALKL-------DELQNPEGCRTAIvNErktktkqgktKKA-----NKKYKVlDEERMKTKE 145 Debaryomyces hansenii
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