4MXW,2O0O,1TNR,1DU3,3URF,4HT1,6MKZ,6CU0


Conserved Protein Domain Family
TNF

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pfam00229: TNF (this model, PSSM-Id:395173 is obsolete and has been replaced by 425540)
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TNF(tumor Necrosis Factor) family
Statistics
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PSSM-Id: 395173
Aligned: 27 rows
Threshold Bit Score: 84.6706
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4MXW_B        60 LGWETTKE--QAFLTSGTQFSDAEg-LALPQDGLYYLYCLVGYR--GRAPPGGgdpqgrSVTLRSSLYRAGGAYgpGTPE 134 human
3URF_A        24 SSWYHDR---GWAKISNMTFSNGK--LIVNQDGFYYLYANICFR--HHETSGDla--teYLQLMVYVTKTSIKI--PSSH 92  human
Q9I8D8       152 LKWMTTS---YAPTSSLISYHEGK--LKVEKAGLYYIYSQVSFCt-KAAAS---------APFTLYIYLYLPM---EEDR 213 chicken
P27548       137 LQWAKKGY--YTMKSNLVMLENGKq-LTVKREGLYYVYTQVTFC--SNREPSS------QRPFIVGLWLKPSS---GSER 202 house mouse
O97605       137 LQWAPKGY--YTISSNLVTLENGKq-LAVKRQGLYYIYAQVTFC--SNREASS------QAPFIASLCLHSPS---GSER 202 domestic cat
4HT1_T        36 SGWEEARI--NSSSPLRYNRQIGE--FIVTRAGLYYLYCQVHFD---EGKA---------VYLKLDLL--------VDGV 91  human
XP_009858906 174 tDWAPPD---SHFKGFGTRHLNNDgyFTVPVAGVYFVYSQVVFN---------------VTNLPFMVSEIGVNV--DGQS 233 vase tunicate
P32971       113 LSWNKDGI------LHGVRYQDGN--LVIQFPGLYFIICQLQFL---VQCPNN------SVDLKLELLINKH----IKKQ 171 human
P32972       118 LSWNEDGT------IHGLIYQDGN--LIVQFPGLYFIVCQLQFL---VQCSNH------SVDLTLQLLINSK----IKKQ 176 house mouse
6MKZ_C        26 LNWHSQDGagSSYLSQGLRYEEDKkeLVVDSPGLYYVFLELKLSptFTNTGHK------VQGWVSLVLQAKPQV--DDFD 97  house mouse
4MXW_B       135 LLLEGAE-TVTPVLDPARrqgygplWYTSVGFGGLVQLRRGERVYVN--ISHPDMVDFA--RGKTFFGAVMV 201 human
3URF_A        93 TLMKGGS-TKYWSGNSEF-------HFYSINVGGFFKLRSGEEISIE--VSNPSLLDPD--QDATYFGAFKV 152 human
Q9I8D8       214 LLMKGLDtHSTSTALC---------ELQSIREGGVFELRQGDMVFVN--VTDSTAVNVN--PGNTYFGMFKL 272 chicken
P27548       203 ILLKAANtHSSSQLC----------EQQSVHLGGVFELQAGASVFVN--VTEASQVIHR--VGFSSFGLLKL 260 house mouse
O97605       203 VLLRAANaRSSSKPC----------GQQSIHLGGVFELHPGASVFVN--VTDPSQVSHG--TGFTSFGLLKL 260 domestic cat
4HT1_T        92 LALRCLEeFSATAASSLGp------QLRLCQVSGLLALRPGSSLRIR----TLPWAHLKaaPFLTYFGLFQV 153 human
XP_009858906 234 TFSRCQFsNTLTRSTPRAsst--rkRFVTCHSNGIVYMKANHGVSLS--VNPPSVEVFLa-PQYTYFGAFLI 300 vase tunicate
P32971       172 ALVTVCE-SGMQTKH----------VYQNLSQFLLDYLQVNTTISVN--VDTFQYIDTStfPLENVLSIFLY 230 human
P32972       177 TLVTVCE-SGVQSKN----------IYQNLSQFLLHYLQVNSTISVR--VDNFQYVDTNtfPLDNVLSVFLY 235 house mouse
6MKZ_C        98 NLALTVElFPCSMENKLVdr----sWSQLLLLKAGHRLSVGLRAYLHgaQDAYRDWELSy-PNTTSFGLFLV 164 house mouse
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