1XMC,1T1U


Conserved Protein Domain Family
Carn_acyltransf

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pfam00755: Carn_acyltransf 
Choline/Carnitine o-acyltransferase
Statistics
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PSSM-Id: 459926
Aligned: 388 rows
Threshold Bit Score: 259.421
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1XMC_A             23 LPVPALEESLKKYLESVKPFAn-eDEYKKTEEIVQKFQEga---gkRLHQKLleRARGkR----N-WLEEWWlNvAYLDV 93   house mouse
WP_012399312        6 LPVPALQDTLSRFLTAAEPLMd-rETLEATRREVERFAShe---gpRLQAALeeFARAeDaegrS-WLSRAWlD-GYLTV 79   Kocuria r...
cebbi:ckrop_0605   28 LPLPSLEQTVAALVSAARAVAp-aDVVDTTRTAGSAFLQhs---gpEVQAKLekFAATeReagrS-WFSAEWlR-SYLST 101 
XP_007795263     2378 LPIPDLAETLRMLADSRRAICs-pEELEETERVVEEFTQsg----lELHNTLktNPSGpD----S-RLD-FYdRhIHLER 2446
XP_001589724     2034 LPVPDLSSSLELHLASVRMFIs-eTQLSQTVSVIQEFINgs---gaELQKRLieQRKEtE----N-WPHAk----LYLRS 2100
EEU37201          133 LPLLDLDSVLDLYFGAIRHLLt-pPELEHMVTLLQRLSDpgg-mgrKLHARLmdRFNDpTi--dN-WLFKPYlEtIFTGR 207 
EEA20741         2575 QPLPDLDDALDFWISTTGHLYs-pEQLQTVQQDIQTIKApdsparrAFQELLktHEHEkMs---NgWYNDVLsDaRWLSK 2650
EPS28980         2631 QPLMDLDEALSMVLDGTRHFAt-eEEYKTLCEAVEKFGHegs-tgrQLYDQLvrKSTDpHv--dN-WMADILtDaLFLKR 2705
XP_003838273     2688 HPLVDLDEAVNDLLNSISHFShtrEEYAELNRKAKALAApgs-lgrKLYNQLraKADDpSv--eS-WIAGPLlKaLYLKR 2763
XP_001591652     2461 QPLPALEDTLRHYINAARPFCs-nEELERTKQLAEELKIvgg-qgqMLQARLleRKNDpTi--eN-WLSDIYlTrRFLRQ 2535
1XMC_A             94 RIPSQLNVNFVGPCphfehywparegtqleRGSMMLW-HNLNYWQLLRREK---LPVhkSgnTPLDMNQFRMLFSTCK-- 167  house mouse
WP_012399312       80 RTPLALTTSVGFQItgdyg------apgvgRAAELVYrAAVVHLRQLRGETpqqVDPr---gNPLSMEQWQCLAGGVR-- 148  Kocuria r...
cebbi:ckrop_0605  102 RTSLLHSTNVSFQInsgflp----stpgvgRAAEFIYrAATIHLDQARGTTpqeTDA--Rgn-pTTMDQWQCFDGGIR-- 172 
XP_007795263     2447 REPLQDHALFYLGHltdgap----ghtqaeRAAIITV-AALNFKKRLESGL---LEQnsLndVALCMETLQWLFHTSQ-- 2516
XP_001589724     2101 RKPLNPYSIFYGTHvsstia-----hsqaeRAAIISL-SAWNFKQRMDTNN---LEQdyLneEPLCMDSLKWIFNANR-- 2169
EEU37201          208 NYPVSPFSTFAGSDtlsrfp-----hrqaeRAAIISL-AALEFKQKLESGR---LEPtvIggRPQCMYLHEWLFNSFRea 278 
EEA20741         2651 RYPVAPYQSIMVTHrdskrl-----qsqaeRAAIISS-SVFSFNRAMKAGK---IEPfwIagKPSCTWRWDWLFNSVR-- 2719
EPS28980         2706 RFPLAPLQSFFATHhesavp-----hpqadRAALIAT-TAFRFKEAVDAGN---LEPhwYfnIPSCMDSWQWLFNTTR-- 2774
XP_003838273     2764 RYPIVPFSSFLGTHfdsava-----hsqaqRAAALTR-TLSEFKRDLDLKK---LKPdfLgeRPNCGHSLTWLFNALR-- 2832
XP_001591652     2536 RASLVATQSYFGTHpngrgl-----htqaeRAAIVTL-AALKFKQRYESES---LPKreLygQSIDTYAYRYLFNVCRep 2606
1XMC_A            168 VPGITRDsimnyfktesEgh---cpTHIAVLCRGRAF---VFdvlhEG---C---LITPPELLRQLTYI-H-----KKcs 229  house mouse
WP_012399312      149 HPRPERDeirrpgaaasSsggearaPELGVIHRGRLYalpVA-----TedrQ---PVPLRTVAEGLREVv-------Ard 213  Kocuria r...
cebbi:ckrop_0605  173 HPQPDFDti------hrSelg-drdREIGVFWAGRLFavpVT-----NhdgA---LRDIDSLAESITAIiHpdadkPAlr 237 
XP_007795263     2517 EPGQEIDiark----------yasnTNVVVMRRGHLYeiaVH---------EqddYA---SLKGLFADIirsse------ 2568
XP_001589724     2170 IPQITMDkmrk----------hadnDYFVVLRRGHVFkvrLA-----KnmsQestYL---LLLKTFLTIlrlse------ 2225
EEU37201          279 LP--GIDemrk----------mpseNYIAVLRRGHLFkvnLT----Y----DqgrHVPFAKLESTFQAIldkvn------ 332 
EEA20741         2720 EPHIGCDkmmr----------yddcNHIAVLRKGHVFkvmLQ---------DhgeDMPLEKLEATFEAIitqvg------ 2774
EPS28980         2775 EPHVEADcmrk----------ypdnDYCIVLRRGHIFkvdLK---------SgseAVPYSEVQGQFEAIlnsvq------ 2829
XP_003838273     2833 EANVGCDkmmr----------ypgkEHVAVLRRGHLFkvsLK---------EgddIVSYQKLKTTYQSIidlnl------ 2887
XP_001591652     2607 HP--NEDiire----------ypseNYIVVFNNGHGYkigLT---------KddeAITFSALKTTFEEIiyepi------ 2659
1XMC_A            230 nep-vgpsIAALTSEERTRWAKAREYLISL-DPE--NLTLLEKIQTSLFVYSIEdssphATPEEYSqvfEMLLGGdPSVR 305  house mouse
WP_012399312      214 epretelpFGALSYLGSAVAAPLLERL----TADahNAEVYERITRMLFVVNLV------EARAEVvehLERSAFeVGHA 283  Kocuria r...
cebbi:ckrop_0605  238 eqtavdlgFAVPSAVGSETLAPILEQALK--QPH--NQHTYRRLTNFLFTVTLT------DEARDDadhLRRSAFePGHS 307 
XP_007795263     2569 ---qamppVSVLTSKKRDDWAVLRSQLKTLgS----NAATLEAIESAAFVVSLDdtapqTssercts--illndrhLTNR 2639
XP_001589724     2226 ---ekipaVATLTADERDSWAELREMVKGI-SPS--NSAALEDIEASTFVMCLDdgspeTptercn-----qflysPSNR 2294
EEU37201          333 ----ddswVGILTADERDSWAEMRQAFKNL-SPD--NKRYLDMVEGAAFVVSLDdgtptTpfermk----cwqlndGFNR 401 
EEA20741         2775 ---ddalwTGILTTDERNSWAMVREKLS---SSSltNAEYFRVIESAMFVLCLDdgfpeTpeerar----qgyigdGSNR 2844
EPS28980         2830 ---degfwTGILTNDDRDNWAINREKLIAL-SEK--NAESIQIIEKALFAICLDdgaptTnserir----kaylgnGFNR 2899
XP_003838273     2888 ---eekmwTGILTTDNRDSWGTIRQKLMSM-DPR--NAEYIKVLEESVFVMCLDdnsptTreervr----fgylgdSFNR 2957
XP_001591652     2660 ---epkswVGILTADNRDDWAKARNALLEA-DES--NKVSIKTIEAAAFIVCLDdgtpeTpsqrfs----qflfgdGSNR 2729
1XMC_A            306 WGDKsYNLISF-ANGIFGMCCDHAPYDAMVMVNIAHYVDERVLETEg--------------rWKGSEKVRDIplPEELVF 370  house mouse
WP_012399312      284 WAYKpITYEVClEDEWLAVHVEHSTVDGATILAVAGQLQDVTVP--------------------DEAPLPDApsPDALTW 343  Kocuria r...
cebbi:ckrop_0605  308 WAYKpISYEISlADSWLSLNVEHSTVDGATLVTAVRRMHDVTVPAS-----------------VSASPEPVAp-PEELTW 369 
XP_007795263     2640 WLDKmLQFTIA-ANGVSSLVGENSKLDGLSARQLSEYITDEIFGTQsvg-----------dkTTPPASAMRR-----LTL 2702
XP_001589724     2295 WSDKsFQFVVC-ENGTSGFICEHTMLDAASSAQINNFVTQYIMDYRpkahs-------dehaNVQIDELLEE-----ISF 2361
EEU37201          402 WFDKgLKFVVC-SNGMSGSVVEHSMIDGMTVRELYDATSSAILTYRrdg-----------pdTLDSRNGVDE-----IKL 464 
EEA20741         2845 WFDKvLQFTVS-ENGRSGLITEHGGVDGTTSARLSEWIAKAIDEYL-----------------PRNIHHYEN-----IQL 2901
EPS28980         2900 WNDKgLQFTIF-ENGSSGYQVEHSMIDGLTVHRMNEWIHEAIHAHVpsnvtnghghangdvnAASNGFQPGL-----EEY 2973
XP_003838273     2958 WHDKtLQLVVT-GNGSSGTIFEHSMIDFMTTSQISQRLQGAIDTLDpen----------dnlEQNGEAAADP-----ASL 3021
XP_001591652     2730 WYDKsLQFVVC-KNGVSASVCEHSILDGITIEVLHEFINEAIISHKpsp-----------ntTPRNPNTPEI-----LPL 2792
1XMC_A            371 T----V-D-EKIL-NDVSQAKA-QHLKA--ASDLQIAAST-FtSF-GKK--LTKE-EALHPDTFIQLALQLAYYRLHGRP 435  house mouse
WP_012399312      344 Q----L-D-DGLR-GDLVAAVA--------GYRAQAALLGvHrVF-VPRphRAELpFRISDDAAQQLIMLLAQYATYGRV 407  Kocuria r...
cebbi:ckrop_0605  370 K----W-S-GEDI-STLKEAAE-GVSQD--LTDIATHIVT------VPHppADQLpFRISADAAQQLILTIAQLKTYGRA 433 
XP_007795263     2703 E------TsPAIA-QAISEQTAsNLARYktIGATRRHYAAlNrSFlGNR--GLRS------KGTVLIAILMATRMFYGYF 2767
XP_001589724     2362 G------TnSTIE-KEIQRVED-NFGQV--HDQPATYIQFyIsTL-GKK--FLQS-FKIPHRAGCHLVIQLASLFHFGKQ 2427
EEU37201          465 EeytcQ-SsPTID-ERIAHVRA-RYLQE--TSIIGFTTWE-CvNF-GQE--YLQL-HKVPAKGIFETMVQLASKYFLGEN 534 
EEA20741         2902 EevvlE-StVEVD-SHIDILKR-RFREN--TSAGTYMRET-LtEF-GTD--FLVQ-GKMPVKQVVDITFQLAVRLFYGRN 2971
EPS28980         2974 A----LtTsPEID-EHILVVRE-QHLKA--TSSREYGYLA-LpHF-GKN--FLAE-HGCPIKSVFDVTIQLASKLYFGHN 3040
XP_003838273     3022 EeiplAsTtKEIE-AHMMMLRD-KYAAT--TGVKIYTPHL-VpSF-GKS--LLLT-NSAPIKATVDLTIQLASRIYFGYL 3092
XP_001591652     2793 I----LnPnLETRtQHILQ----NLSRQ--TSKYTFTHFE-ThKL-QQK--FLSE-KGLPTQSSIQLAIQLAIQRFFNYI 2857
1XMC_A            436 GCCYETAMTRYFYHGRTETVRSCTVEAVRWCQS--MQdpsA----------------SLLERQ------Q----KMLEAF 487  house mouse
WP_012399312      408 RGVYEAVDMREYQAGRTECLRPVTPEAVAFVRAlhA---------------------GIATEE-----------LFRAAL 455  Kocuria r...
cebbi:ckrop_0605  434 RGVYEAVDMREYRAGRTECLRAVTPQAVEFASL--LL---G----------------GEATRQ-----------DLDDVL 481 
XP_007795263     2768 EPVWETVTVAKYAKGRIDWLQSLTPDIVRWIEA------------------------ALGFKQerkgdvAdlasKLKDAG 2823
XP_001589724     2428 YPCWEALTTMFFRLGRVDWMQVVSPAMYEFCAS------------------------VAENQKsatelkA----LLREAA 2479
EEU37201          535 HPCWSAISMGHAHKGRPEIIQTYTAELKAFCDA------------------------ADNTSIearkrqT----LLFAAA 586 
EEA20741         2972 IPSWESISVAYYHQGRTESVQRALAAVVSFCDA-------AakayngedgigatpvdTVKLAA-----------LLSTST 3033
EPS28980         3041 PASWEPMSMAHFHKGRTEIFQGVLPSVAQFCES------------------------ACDETMpadqrrD----MLIRAA 3092
XP_003838273     3093 PASWETVSTAHYHLGRPEIVQVVLKSVVEFCDA------------------------ALDTAVprsearA----KLLKAA 3144
XP_001591652     2858 PNAIETVSLAQFRQGRVEVHHIITPLMAQF-----L---------------------ATNKQTlnihsrE----LLYEAA 2907
1XMC_A            488 AKHNKMMKDCSHGKGFDRHLLGLL--------L------IAKEeglpvpeLFEDPLFSRsg-gGGNFVLSTSL-VGYlr- 550  house mouse
WP_012399312      456 DAHRGWVKACKSARGVDRHLLGLA--------MtaertgEPSA-------FFDTPALAA----VRHDFLSTTS-IGGpdt 515  Kocuria r...
cebbi:ckrop_0605  482 GAHRAWVKACKRGAGVDRHLLGLRftaaameeAgke--ltgTG-------FLTDPGVAA----TTYDFLSTTS-IGGady 547 
XP_007795263     2824 AGHVQSLRRIADGRGYVEPLYALMgaalse--------------gkplpaLFESSAWKYsdrhLSPKMAKTDC-LGSggy 2888
XP_001589724     2480 SVHSSTMTKNGRGLGFLAHFHALEgmiaedepIp---------------aFFEDPTWK------MAWKWATKK-IKTdsa 2537
EEU37201          587 RSHVANVNRVQQGKGYERTMSAMQtvlkddeaMp---------------eIYNDPTYIS----MRPHWLMTGS-TDLggs 646 
EEA20741         3034 KQMNANMQEILNGRSHIRVMELLNwvwpsdaaIpkprs--------lsegLFHGRPSVY----AQSNALETDMvIDD--- 3098
EPS28980         3093 NDYTAGLQTSGKGNNYFRLMNVLEtmwpsdeePa---------------lLFKDPVWLK----TYPRLIMSGL-TDGgs- 3151
XP_003838273     3145 RECNAQIVKGGEGRNYFRLMDVLEvlsheaqdDgssegqIVPE-------LFSDPVWKR----SYPRLIMQTM-IEKkla 3212
XP_001591652     2908 KEHAKSLTRASKGRGFSRHLLALEwmikegeeTp---------------aFFQDAVYAR----MKPERAVTSC-FNTgwl 2967
1XMC_A            551 ---vQGVvVPMVH-NG--YGFFYHIRDDRFVVACSswrsCPETDA----EKLVQMIFH 598  house mouse
WP_012399312      516 -ivrYAF-APTTR-EG--FGVTYTTCTDGYEFCVNh-----RRDTsedlEGFAHHLTA 563  Kocuria rhizophila
cebbi:ckrop_0605  548 -fvrYAF-VPSVP-EG--FGISYTPQPESFEYCVTw-----HPSRadqpDDFLRALPQ 595 
XP_007795263     2889 lr--mqegGFLMP-NPdtVFIHYEVHHADPLVLVQg----REEDV----ARFEGCLDE 2935
XP_001589724     2538 agfiyqeaGYLMP-DPesFLVHYEVEDERCFFWIQg--------TgdhpRRFQEALER 2586
EEU37201          647 g---ggefGMVLR-YPdsVWVQYVVDAASAKFSIVt----GRDRT----QRFCECMER 692 
EEA20741         3099 ------F-VSLLP-NPegFWTIMMPEKNSIRLSLTg---GSQERT----TAFSKQLHR 3141
EPS28980         3152 ------rdSAFSLiDPegVWICYSIEEQEARFSIVg----PTGKV----SEFEKVLDE 3195
XP_003838273     3213 -----qdpGYTMQ-DPenVWMNYTVNEDSLEVCFVa----PRTGA----ERFKAALDR 3256
XP_001591652     2968 ------egGFVYP-FPgsILVYFEVKRESVSFSIFg----NDADV----ERFRELLEV 3010
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