Conserved Protein Domain Family
MEA1
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pfam06910: MEA1 
Male enhanced antigen 1 (MEA1)
This family consists of several mammalian male enhanced antigen 1 (MEA1) proteins. The Mea-1 gene is found to be localized in primary and secondary spermatocytes and spermatids, but the protein products are detected only in spermatids. Intensive transcription of Mea-1 gene and specific localization of the gene product suggest that Mea-1 may play a important role in the late stage of spermatogenesis.
Links
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Statistics
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PSSM-Id: 429188
Aligned: 24 rows
Threshold Bit Score: 99.4894
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_004077068  59 GEYHYQPLNQEPDGLNGMEQQEEEEETGgvdgsshAQQlqqvqqrieVMGLhlpEAPPpDSeeeEEEDDp------eGAA 132
XP_002051609  38 AYDGYQPLATDAEEAGAVINDIV-TAGEsngrqeaDED---------IDLMtaeVTHGdPNmppIESIDaeierqvwNEP 107
ETN58453      45 GYAGYQPLSVDERNPSTLRVIPM-DDYEaqsdeseTGNa--------------------VAdtdTTNHIeflnldvwNAP 103
KFB39777      44 AYEGYQPLNVDELNQPNRRLSPMEDDMEsgmdvdsNDPa--------------------ESdprSTVNTellnvdvwNAP 103
EAU76389      51 GYAGYQPLNMDELNHPNRRPSLMEDEAEsgvgegeTVG----------------------LdvaNSINAdflnvdvwNAP 108
VDO09384      61 ENGSTIPLDDTGVDEALMRVLNSDGTHFgsfpvseEPK---------------------------DEPDesspallwNEP 113
XP_001602458  36 GPAGYMPLSQIPAEGEPLEDENDDDDEDfewthapTEP----------------QQSLpESnepGEPSVdpetlevwSA- 98 
XP_017797647  37 GMAGYVPLSQIPADSDPMLYEDEDDEWIsnagepsQAFp--------------------TPsldSQQDCmsetievwSS- 95 
EZA60349      37 GMAGYVPLSQVSTDADPILDDDENDEWLsgigessQAQ-------------------AsSStvdSQQSCssevlevwSC- 96 
XP_012056001  38 GMTGYLPLSQVSTDAEPILGEEENDEWLtgfgesnQASs--------------------VPateTQQSCssevlevwSC- 96 

XP_004077068 133 aLRSRSSIPMDADHVELVKKTMAAVALPSLGVPPWAQEISDDQWKDMVQHTLQTRQSA 190
XP_002051609 108 -RPQELQMELDKTRTEQILKAMSKITLPNVTVPDWAKGVPEERWKHELLERIQTRKAA 164
ETN58453     104 -RPDELNIDIDANKAAEIVNVMAGIKLPTTAVPDWARGVPEEEWKENLLQRIRQRQQP 160
KFB39777     104 -RPNELNIDIDPTKAAEIVNVMAAIKLPTTAVPDWARGVPEEEWKENLLQRIRQRQQP 160
EAU76389     109 -RPNELNIELDSSKAAEIVNVMAGIKLPTTAVPEWARGVPEEEWKENLLQRIRQRQQT 165
VDO09384     114 rKDADQRIPLPDEKATEIKACLSDFKLPETCLPAWAKEIPEDVWIQHLLQRISPQSNA 171
XP_001602458  99 -PGNSSNIDLDADKINQVKSAMASFTLPTTAIPDWANSISEDQWKEQLIHRIKEIQKD 155
XP_017797647  96 -SYNQSNIDMDADKINQVKSMMASFTLPTTAIPEWAKAISEEQWKEQLIGRIKEIQNR 152
EZA60349      97 -SQNRTDIDLDAAKIKQVKSVMASIKLPETSIPQWASAISEEQWKEQLLVRIKEMQNK 153
XP_012056001  97 -SHNRSDIDLDATKIKEVKSVMASITIPEACIPQWANAISEEQWKEQLLIRIKQMQDK 153
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