Conserved Protein Domain Family
PRK00855

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PRK00855: PRK00855 
argininosuccinate lyase; Provisional
Statistics
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PSSM-Id: 179143
Aligned: 649 rows
Threshold Bit Score: 388.74
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
89900499    7 DKKSQAW-SAL--FSEPMSDLVKRYTASVFFDKRLWQADIAGSLAHADMLAAQKIISSEDHNAIQSGMATIS-AEIESG- 81 
15921796    1 MVLYRRW-GTE-------KDFVSTYTSSIDSDKEIVEEVKVVMKAHVIELYLSGYITKDTAKRILLAINSF--HELKEG- 69 
18976580    1 --------MYRkaLLGSTRLDILSYISSMEEDREIVEEVIECLIAHVKGLIHSKLIPEEEGEKILKAL-----EELRASk 67 
70607353    1 -MLYRRW-GSD-------KDFVISYTSSNESDKEIVEEVKLTLKAHVIELYLSNYISKDTAKKIIRAINSFK-DYPSSG- 69 
18313664    1 MSFYRSWiGGT-------GDLVKKYTSSIKDDVELAEEVVRVMKGHVAHLVEIGSIPKEAGERIIKALEEVD-------- 65 
126458991   1 MAFYRSWiGGG-------GDLVRRYTSSMADDVEIAEEVVKILKTHVAHLAEVGVIPREAAERIAKALDEVDyDALAKG- 72 
145591201   1 MSFYRSWiGGR-------GDLVQRYTSSIRDDAEIAEEVVKVMKAHVTHLAEIGALRKEVADKIVAALEEVDpTELLRG- 72 
146304736   1 -MLYRKW-GSK-------EDKVVTYTSSSREDVRILDKVKEVMKAHVIELFLSGNLSKEDARKLLQGINSF--TKVDPS- 68 
171186276   1 MSFYRSWiGGE-------GELVRRYTSSIRDDAEIVEEVVKIMEAHVRHLAEVGAAPKEAAEAVAKALREVEpERLLTS- 72 
119871796   1 MSFYRSW-IGE------EGELIKRYTSSIKDDVEIAEEVIKVMEAHVKHLAEVGIMPKEAADAILKTLKEATpEQLLSS- 72 
89900499   82 AFDWKLE-LEDVHLNIEARLTQLIG-LAGKRLHTGRSRNDQVATDVRLWLRGEIDLIGALLTDLQKALLEVAEKNVEVIL 159
15921796   70 --------YEDIHEALEDHIIKTVG-EEGGWVGFGRSRNDHVATALRLKMRKYLIEILYDIISLRKTLIEKSKTSTEILF 140
18976580   68 EALFSIE-AEDIHEAIEIYLKEKLG-KTGGYLPLGRSRNDHVVCALRLKAKKALVEEIGLILELRKALIKKAEENVYTLM 145
70607353   70 --------YEDVHEALEDYIIKNIG-EEGGWVGLGRSRNDHVATALRLRTREYIFDIMEELYLLRKSLIEQAKKNLNTIM 140
18313664   66 ASELLKEeFEDVHEALEKWLIDKLGeEIGGWVGLGRSRNDHVAAAIRLAALRKTERLKEEACRLRCALAKRALEYADCPM 145
126458991  73 ------G-FEDIHEAVEKWVIDRVGeEAGGWLGLGRSRNDHVAAAIRLAALRKLAELKRGLAALRCALAKRALQYADCAM 145
145591201  73 ------E-FEDIHEALEKWLIDKLGeDVGGWVGLARSRNDHVAAAIRLAALKKVGALREAAMRLRCALAARALEYADCPM 145
146304736  69 --------YEDVHEALEDHLIKTAG-EAGGSIGLGRSRNDHVAAALRLEIREELMDLLEQLLDFRKMILKRAEENVNTPF 139
171186276  73 ------E-FEDVHEALEKWLVDRLGeEVAGWIGLGRSRNDHVAAAIRLAALRKTGVLKKAVERMRCVLAKRALEYADCAM 145
119871796  73 ------E-FEDIHEALEKWLIDRLGeETAGWVGLGRSRNDHVAAAIRLAALRKASALRKNVEKMRCILAKKALEYADCAM 145
89900499  160 PGFTHLQVAQPISFGHHMLAYVEMFSRDAERMSEVRRRTNRLPLGAAALAGTSYPLDRERVAVSLGMvdekghPCVCQNS 239
15921796  141 PTYTHFQPAQPSTLAHYFLYIEDELDTIWNYIYSSLLLVNRSPLGSGAIVGTNVKLDRKREAELLGF------DDIIYNT 214
18976580  146 PLFTHLQPAQPSTFAHYLSAIIEELEDITKILFSGLGIVDKSSLGAGAIGGTSVLLDRGYMGGIL-F------SDIITNS 218
70607353  141 PSYTHFQPAQPTTLAHYFMYLEEELNTPWEALFNSLKLINRSPLGSGAIVGSNVKIDRKREAELLGF------DDVLYNT 214
18313664  146 PSFTHFQPAQVITFGHYLLAIDELLAEFLHILRGVEDLLNRSPLGAGPAGGVRTPLDRRRLAELVGF------KEVVENA 219
126458991 146 PSFTHFQPAQAITFGHYLLSIDELVEEFSRALAGVEPLLKRSPLGAGPAGGVKTPIDRRRLAKALGF------EDVVGNA 219
145591201 146 PSFTHFQPAQVVTFGHYLLAVDELVAEFLHVLAAAEDLAKRSPLGAGPAGGVRTPVDRRRLAELAGF------KDVVENT 219
146304736 140 VVYTHFQPAQPTTFGHYLLYVEEEVASRWSSIFRTLDLVNRSPLGSGAIVGTSVKLNRDRESNLLGF------REVLVNT 213
171186276 146 PSFTHFQPAQAITFGHYLLAVDELAGEFLHVLKPVEELLKRSPLGAGPAGGARAPIDRERVAKLAGF------EGVVENA 219
119871796 146 PSFTHFQPAQAITFGHYLLAVDELAAEFLHVLKAVEKLLKRSPLGAGPAGGTRTPIDRERLAKLAGF------EDVVENA 219
89900499  240 LDAVSDR-DFAIEFTAAASLCMVHISRMSEELILWMSQNFGFIKIADRFTTGSSIMPQKKNPDVPELARGKTGRVVGHLM 318
15921796  215 ISATSSR-LDLINAVSNLSLLMLFFSRIAEDLILLSSMFINIVKLPDSHVSTSSLMPQKRNAVTLEILRSKAGECFGDLS 293
18976580  219 LYATSSR-TFLLYSCFLSVLISIALSRIAEDFVIFSTPNFGYIKLPNEHLSTSSMMPQKKNPVTMEVARAWAGEAIGHLV 297
70607353  215 ISSTSSRiDF-INAISSLTLLMLVLSRFAEDMILLSSMFVNIIKLPDSHVSTSSLMPQKRNSVTMEILRTKVGECYGDLS 293
18313664  220 LYASGSR-FFALALASAVVSFLAELSRAVDDFIRWNSPVVGYVNSPDSHVSTSSIMPHKRNLVTLEVLRARIAEALGHFA 298
126458991 220 LYASGSR-FFASAAASIVVSFLVELSRYVDDFIRWNSPAIGYVKAPDSHVSTSSIMPHKRNLVTLEVLRARISEAVGHLT 298
145591201 220 LYASGGR-FFALALASAVTSFLVELSRAVDDFIRWNNPLLGYVEAPPEHVSTSSIMPHKRNLVTLEVLRARSEEAVGHYA 298
146304736 214 ISATSSR-ADLISAVMEVVNLMLALSRVVEDMILLSSKFVGILELPDTHVSTSSLMPQKRNAVTMEVLRARVSRVLGYLT 292
171186276 220 LYASGSR-FFALALASAVVSFLVELSRAVDDFIRWNSPLVGYVAAPDSHVSTSSIMPHKRNLVTLEVFRARAAEALGHLA 298
119871796 220 LYASGSR-FFALALASAVVSFLTELSRTVDDLIRWNSPLVGYVAAPDSHVSTSSIMPHKRNLVTLEVFRARAAEALGHLT 298
89900499  319 GLITLMKGQPLAYNKDNQEDKEPLFDTVDTLKDTLRIFAEMIggqlnpatgikeGGISVNPQAMEQAALKGYATATDLAD 398
15921796  294 SLFNIYKGLPSGYNLDLQEMNKHYWDCVKIVNSSIEVINSIL------------EGIEVLNFQLDDK-----TTATDVAE 356
18976580  298 AMMSILKALPSGYNLDMQEVNKHAFALFSGTIKTLKIFVDAM------------KRVEVNKENMKKDCDIFPILATDYAE 365
70607353  294 SLMMIYKGLPSGYNLDLQEMNKHYWNCIKHVIPSIHITRDII-----------------QNIQIKNFGEIQGLTATDLAE 356
18313664  299 AMSALVMKVGMGYSLDLQEATRHLWAVLNIATEGMAVFRDFI------------ENMAFNCEKSRKDAEAYFTTSSDTAE 366
126458991 299 ALYAVQAKIGAGYSLDLQEATRHLWAILKIAGEGVEVLRDFV------------EGLEFNCEKARLDAETYYATSSDTAE 366
145591201 299 ALSGVVAKVGLGYSLDLQEATRHLWDILNIAIEGVEVLADFV------------EKIKFNCEKGRRDAELYYATSSDTAE 366
146304736 293 SIASTYKSLPSGYNLDLQEINPLFWEIIDETRTGIEVLHDLL------------SKVKVNEFKIDKEV-----LSTDEAE 355
171186276 299 ALHAVVMKIGMGYSLDLQEATRHLWAVLNIASEGVEVFTDFL------------EKMSFDCGRARRDAERYYSTSSDTAE 366
119871796 299 ALNAVVMKIGLGYSLDLQEATRHLWAVLNMATEGVEIFIDFL------------EKMSFNCVKAREDAERYHSTSSDTAE 366
89900499  399 YLVKK-GLPFRDAHETVAHAVKA----AithqvdlsELPLAV-LQQfnpgiEKDVYE-VLSLRGSLNARDILGGTAPNQV 471
15921796  357 DLAIT-GIPYRKAYMEVANKIRAgtfiS------------------------------EISPKTSIYKKAVIGSPNPELI 405
18976580  366 KIAMNtGRPYREVYMEVASIIGE-------------HESTEKiYSE-----LSSKYGiSISLEEGIKKP-VVGSPNPEDV 426
70607353  357 EMAIS-GIPYRKAYIDVANKIKAgtfvA------------------------------GISYTKSIENKKVIGSPNPSLL 405
18313664  367 DEALK-GVPFRKAYFQLASAIKA----G---------------TAR------------LLTINEALKRP-VYGSANTEEV 413
126458991 367 AIALS-GVPFRRAYFQLAEEIKR----G---------------SAK------------LLSPEEAVKRP-TEGSANPEEV 413
145591201 367 ERALR-GVPFRKAYFELASEIRE----G---------------KAR------------LLTVDEALKRP-VLGSANPEEV 413
146304736 356 ILAEK-GMRYRDAYFAVAKAVREgkfsP------------------------------TITPEQSIYRKAVKGSPSPERV 404
171186276 367 EAALR-GVPFRRAYFQLAREIRE----G---------------AAR------------LLPVDEALR-RPTRGSANPEEV 413
119871796 367 TIALS-GVPFRKAYFQLAKEIKE----G---------------TAR------------LMSIEEALQRP-TRGSANPEEV 413
89900499  472 RAQIARHRARLG 483
15921796  406 NEEIKIKENRIA 417
18976580  427 LEFLEKAKKNVE 438
70607353  406 TQEIEIKEKRLN 417
18313664  414 KRAASRRLALCR 425
126458991 414 RRAASARLIFCK 425
145591201 414 RKSASRRLALCR 425
146304736 405 RESISLARERLN 416
171186276 414 KRAASARLVFCR 425
119871796 414 KKAASTRLVFCR 425
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