Conserved Protein Domain Family
RIFIN

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TIGR01477: RIFIN 
variant surface antigen, rifin family
This model represents the rifin branch of the rifin/stevor family (pfam02009) of predicted variant surface antigens as found in Plasmodium falciparum. This model is based on a set of rifin sequences kindly provided by Matt Berriman from the Sanger Center. This is a global model and assesses a penalty for incomplete sequence. Additional fragmentary sequences may be found with the fragment model and a cutoff of 20 bits.
Statistics
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PSSM-Id: 273647
Aligned: 13 rows
Threshold Bit Score: 318.99
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
AAC71797        1 MKLYYSKILLFSLILN-ILVPSSY-----AHNK-----NKQYIsartptITSRMLSECDINT-SIYDDDTEMKFVKENFD 68  Plasmodium fal...
TIGR:PFB0040c   1 MKDHYINILLFALPLN-ILVYNQR-----SYYI-----TPRHT------ETNRSLCECELYSpTNYDSDPEMKRVMQQFE 63  Plasmodium fal...
AAD55383        1 MKIHYINILLFELPLN-ILIYNQR-----NHKS-----TTHHTlk---iPITRLLCDCELYSpANYDDDPQMKKVMKNFN 66  malaria parasi...
CAB39060        1 MKVHYFNIFLFSLPLN-IILLSSQ-----VYNQ-----RNHYMkp--htYTNRSLCECELYApSNYDNDPEMKAVMQGFD 67  Plasmodium fal...
CAB89212        1 MKIHYTNILLFPLKLN-ILV---------NTHK-------KPSitsrhiQTTRLLCECELYT-PNYDNDPEMKSVMQQFH 62  Plasmodium fal...
CAB39057        1 MKVHCYNILLFSFTLI-ILLLSSS-----QVNNqmnhyNRAHMknieptKSYRSLCERELYApANYDNDTEMKRVMQQFE 74  Plasmodium fal...
CAB89216        1 MKFHYINIFLFALPLN-ILVHNKR-----NHMK-----TIICTpktkqtKTHRTLCECELYApSNYENDSEMKEVMEIFD 69  Plasmodium fal...
AAC71802        1 MKVHYINILLFTLPLN-ILVNGQG-----HYSS-----TKHPIsstkssKYHRSLCECEIYTs-IYDNDPEMKKVMQDFD 68  Plasmodium fal...
CAB39120        1 MKIHYINILLFALPLN-ILVNNQR-----NHNN-----STYHTsntktiKSHRSLCECKLYAqSNYENDQEMKDVIKEFN 69  Plasmodium fal...
TIGR:PFB0055c   1 MKLNYTKILLFFFPLN-ILAN--------NNKN-----KPSITqrhtprYTSRVLSECDIRS-SIYDNDAEMKSVKETFD 65  Plasmodium fal...
CAB39058        1 MKLHYTKILLFFFPLY-ILVTSYHv----YSKN-----KPSITshhtpiTTSRVLSEKDLQS-SIYDNDADMKSVKENFD 69  Plasmodium fal...
CAB89214        1 MKLHYTKLLLFFFTLN-ILLTSYHa----HNKN-----KPSITphhtrsTTSRLLSEYDTES-SIYDSDDEIDSVKEIFE 69  Plasmodium fal...
XP_001351875    1 MKVHCYNILLFSLLLHrLLLSSSKvniemNHHN-----TPHIKnre-ptKSYRSLCECELYT-YIYDDDPDMKEIMNDFD 73  Plasmodium fal...
AAC71797       69 RQTSQRFEEYNERLLENKQKCKEKCDKEIQKIILKDKLEKELMDKFATLQTDIQNDAIPTCVCEKSLADKTEKFCLNCGV 148 Plasmodium fal...
TIGR:PFB0040c  64 DRTSQRFHEYEERMQSKRMQCKEQCDKEIQKIILKDKLEKELMDKFDTLHTDIQSDAIPTCVCEKSLADKVEKGCLRCGY 143 Plasmodium fal...
AAD55383       67 RQTSERFHEYDERMKTTRQKCKEQCNKEIQKIILKDKLEKELAEKFVTLQTDIQNDAIPTCVCEKSLADKVEKGCLRCGS 146 malaria parasi...
CAB39060       68 RQTSQRFEEYNERLLENKQKCKEQCNKEIQKIILKDKLEKELMDKIVTLDTDIQSDAIPTCVCEKSVADKVEKTCLKCAG 147 Plasmodium fal...
CAB89212       63 DRTTQRFHEYDENLKEKRQKCKDKCDKEIQKIILKDKIEKELTEKFSSLQTDIHSDAIPTCICEKSLADKVEKNCLKCTQ 142 Plasmodium fal...
CAB39057       75 DRTSQRFHEYDERMQSKRMQCKEQCDKEIQKIILKDKLEKQMEQQLTTLETKIDTDDIPTGVCEKSLADKTENFCLNCGK 154 Plasmodium fal...
CAB89216       70 RQTSERFREYDERMQHKRKQCKEQCEKDIQKIILKDKIEKELTEKFGALQTDIRTEDIPTCVCEKSVADKTEKVCLNCGK 149 Plasmodium fal...
AAC71802       69 QQTSQRLREYDERLIKNRQKCKDQCDKDIQKIILKDKIEKELTKQLEALEVDITTEDIPACVCKKSVEDKVGKNCLKC-G 147 Plasmodium fal...
CAB39120       70 DRTAQRFEEYNERMQVKKNQCKEQCDKEIQQIILKDKIEKELTERFSALETKIDTNDILTCICEKSVADKVEKTCVKC-G 148 Plasmodium fal...
TIGR:PFB0055c  66 RQTSQRFEEYEERMKGKRQKRKEQRDKNIQEIIEKDRMDKSL-------------------------AEKVEKVCLRCGF 120 Plasmodium fal...
CAB39058       70 RRTSQRFEEYEERVKDKRQKCKEQRDKDIQKIVLKDKMEKNL-------------------------AEKVEIGCLRCGC 124 Plasmodium fal...
CAB89214       70 RQASQRLREYDERLQEKRQKRKEQRDKNIQKIIHKDKMEKNL-------------------------AEKIEKGCLRCGC 124 Plasmodium fal...
XP_001351875   74 RQTSQRFEEYNERVNKNRQKCKEQCDRDIQNIILKDKVEKSL-------------------------SEKVEKGCLRCGC 128 Plasmodium fal...
AAC71797      149 QLGgGVLQASGLLGGIGavaVNAWKDAAleaaidfateagAAAGVAAGEAA------------GKAVVIKSLK-Yfr--v 213 Plasmodium fal...
TIGR:PFB0040c 144 GLG-TVAPTVGLIGAIA---VNEWTKAA------------TAAATQKGIEAgi--------nvVIDTLKRLFNiE----- 194 Plasmodium fal...
AAD55383      147 VFGgGVAPSVGILGGIG---QLGLDAWKaaai----ktatKEAIAEAT-KTat--------qeGMNAVISKINeLltk-f 209 malaria parasi...
CAB39060      148 VLGgGVTPAWGLISGIV---YTGWKTAAlaaa----tkeaIAEAAAKGAAAgl--------kaGVKSVISEVSsLfg--v 210 Plasmodium fal...
CAB89212      143 NLGkIVAPSSGVLAGISeaaLSVWKTTEiaaamelakqagAAAGLKAGHLA------------GTNAVIEQLR-Tlg--i 207 Plasmodium fal...
CAB39057      155 NMT-AIAPWWGLVCGVGyagWS--HYVPiav-------------akAAMDA------------GMNVVINALK-Klg--v 203 Plasmodium fal...
CAB89216      150 TMG-AVAPAWGFVSGIG---YVAWTQYV------------AAKILEVGIKKsv--------qvSLDKVMEIVTqIhsltt 205 Plasmodium fal...
AAC71802      148 GILgGGIPGLGVLGAYAvnsMV---QVAmd--------aaKKAAIAEGAEAgi--------aeGIKVAIQGVPkKfl--l 206 Plasmodium fal...
CAB39120      149 RILgTAVPELSLIGGIAvy------aAAqs--------atMKTFISE--------------------TIDVLNrIgg--m 192 Plasmodium fal...
TIGR:PFB0055c 121 GLG-GVAAGVGIFGAIAv---nEWTKAAlv--------aaAQKGIDAGIKS----------------ALKGLEkIye--l 170 Plasmodium fal...
CAB39058      125 ALGgGVAPIWGLVSGLWy---aTWSQYVsa--------kvLEEATNAAIKAg------------IIKAIEGLKeLqd--l 179 Plasmodium fal...
CAB89214      125 GLG-SVAGSIGLFGAVAi---nIWKPAAld--------aaITAALNANAVKiaaaanaageviGKALVIAELQ-Kmg--i 189 Plasmodium fal...
XP_001351875  129 GLG-GVAAGVGIFGALGt---yGWKVAAta--------taIEFATQEGIKAg------------IQAAIEQIK-Itv--f 181 Plasmodium fal...
AAC71797      214 dVFFPKIFNSIGNAIPYYDAKTIGAAIAEKHAQNCALV------STNEG-----AMCYPFEVNLGIReAitftqtgppa- 281 Plasmodium fal...
TIGR:PFB0040c 195 -VVTDLKWKTLITAQNYTDKILVGDVIRKLGNTLCGGS------EDTAG-----GFCLFTVKANTLP-Q----------- 250 Plasmodium fal...
AAD55383      210 qgEPVVDLTRIVNPSTFDKGTALFETADKLFGEACIIP------GTKTNy----SFCTTAIYYD-GE------------- 265 malaria parasi...
CAB39060      211 sTIDDKALGLVINATNYRDAQLISGAIYKQFEMTCMPP------GALPNls--nPICISMWSKFVSTnGssrdlikn--- 279 Plasmodium fal...
CAB89212      208 yFVGDKLLETIIDVTNYMNVSFIYDKVYSHYTTSCTPS------LVNd------QLVGTFNTSDPFCnLvhsnlqgsfyr 275 Plasmodium fal...
CAB39057      204 eKLTAVILKEISRTGNYANIINFSSIISTELKAVCRVT------LSSPs-----D--GAMREGICSIlKkgrtppt---- 266 Plasmodium fal...
CAB89216      206 aEIPKFSAAQILSSGNFTNNISLIDMVQYLRNNMYGVI------ESQKCe----RFGFILDTMGKNTlK----------- 264 Plasmodium fal...
AAC71802      207 yTLNGKELQAVINANNFQNPSFFYGEIMAEYVSWKKSD------MVNSYg----LFSFIEESCE--NnPdki-------- 266 Plasmodium fal...
CAB39120      193 sQLFGAKISQFVTPSIYGKPMTLVTTILSEKEKLCLCV------ANKKK-----LLCGGIERSfe--------------- 246 Plasmodium fal...
TIGR:PFB0055c 171 sDFSYLKWSAMVTPTTYDQPMDLIAIVTKAYN-MCDDV------EAAKGs----LFCQAMEGIANEPdgc---------- 229 Plasmodium fal...
CAB39058      180 gKLVGDKWSNIVTPETYSNPNLLSRALQRVNIAMCYSE------SNENv-----LFCNAIQRRPESvfv----------- 237 Plasmodium fal...
CAB89214      190 sTLKGQTLKSFFRTISYKNVSSITKAVYGQHYEICVYDpsrnllSSFGDvnrhiGICNSVWKQISAVsQrgqyishe--- 266 Plasmodium fal...
XP_001351875  182 nSLLNVEWLNFINASNYNSIAGLVEAVKAAVV---STEr-------TSe-----LSSNTMDRVRNALsea---------- 236 Plasmodium fal...
AAC71797      282 ---kyaipdtvsEIVEGAEQAAKAAAKAAEK-----------GVTAAIKAKETrlleaGFNSSISSINASIIAIVVIILI 347 Plasmodium fal...
TIGR:PFB0040c 251 ------------AINGHVTKAISEGTAEVVK-----------VTEAEMGKVTT-----SAGAYSTGIIVSVVAIVVIVLI 302 Plasmodium fal...
AAD55383      266 ------------YNIKNFGKVGADVYKATYT-----------SQKGTLEAAKVgaveaTYGGYQTAIIASIVAILVIVLI 322 malaria parasi...
CAB39060      280 -----niktyvqSFVSQAETTAAHVTKTTTE-----------KVTTELTTEKTgeiaaTYMGYQTPIIASIVAILVIVLV 343 Plasmodium fal...
CAB89212      276 ssaqtiiyekveEAVAGAEQAATTKTAVMTP-----------IYTTEFTAKNIaeveaATTSYYTPIIASIVAIVIIVLI 344 Plasmodium fal...
CAB39057      267 ------veqvvsGAFKLIDEKAPQAAKAAKQ-----------IEAANYTSTTSsl--------tTGIIASIIAIVIIVLI 321 Plasmodium fal...
CAB89216      265 ------------VFNRNYHIQVEAVKNAVDA-----------AEAAESLKLAT-----NTSILTNTIIASVIAILVIVLV 316 Plasmodium fal...
AAC71802      267 ----------mkFILANSNDIAKDAGKAATKmttqttealtlKKTAEATSTSA-----IFS---NPIVISFIVLVIIVLI 328 Plasmodium fal...
CAB39120      247 -----------qNLPARIAYAVNQGVHTAN------------ETWATATTPTT-----FLT---NPFVASSIAIMIIVAI 295 Plasmodium fal...
TIGR:PFB0055c 230 ---------pvkTFSQMAVDAAEAAGKVS----------------KTTEEAGIalannTSYNSYIAIAYSVTAILIIVLI 284 Plasmodium fal...
CAB39058      238 ----------paSKVAADAGEAGKAVYLA-----------------T-EKAELlkiapATNALTTAIIASVVAIIIIALV 289 Plasmodium fal...
CAB89214      267 ----evikrtveTMMSEAEVSAKAAAKTAEA-----------ANKLAIEEAQEqvmeaTIYNWYTTIGYTILAILIIVLI 331 Plasmodium fal...
XP_001351875  237 ---------enwFSPAVREGTQTTASTIT-----------------TVQRTQLvdvtaTSTYSYMAIAYSVIAILIIVLV 290 Plasmodium fal...
AAC71797      348 MVIIYLILRYRRKKRMKKKHQYIKLLEE 375 Plasmodium falciparum 3D7
TIGR:PFB0040c 303 MIIIYLILRYRRKRKMTKKMQFMKLLNE 330 Plasmodium falciparum 3D7
AAD55383      323 MVIIYLILRYRRKKKMKKKLQYIKLLEE 350 malaria parasite P. falciparum
CAB39060      344 MVIIYLILRYRRKKKMKKKLQYIKLLEE 371 Plasmodium falciparum 3D7
CAB89212      345 MVIIYLILRYRRKMKLKKKLQYIKLLEE 372 Plasmodium falciparum 3D7
CAB39057      322 MVIIYLILRYRRKKKMKKKLQYIKLLEE 349 Plasmodium falciparum 3D7
CAB89216      317 MVIIYLILHYRRKKKMKKKLQYIKLLKE 344 Plasmodium falciparum 3D7
AAC71802      329 LLIIYLILRYRRKRKMKKKLQYLKLLKE 356 Plasmodium falciparum 3D7
CAB39120      296 VLIIYLILRYRRKQKIKKKIQYIKLL-- 321 Plasmodium falciparum 3D7
TIGR:PFB0055c 285 MLIIYLILRYRRKKKMNKKLQYTKLLNQ 312 Plasmodium falciparum 3D7
CAB39058      290 MIIIYLVLRYRRKKKMKKKLQYIKLLNE 317 Plasmodium falciparum 3D7
CAB89214      332 MIIIYLILRYRRKKKMKKKAQYTKLLNE 359 Plasmodium falciparum 3D7
XP_001351875  291 MIIIYLILRYRRKKKMNKKAQYTKLLNQ 318 Plasmodium falciparum 3D7
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