15641248 14 LMSVVTLAALVIFAGLLLYLFGLQKKAATLSRQVLFGLVLGSAFGLALQVVLGEGH-------PAIQETLSWVAIVGNGY 86 Vibrio cholerae 15595074 4 ISILYTLINIIIMLILISIVYLCKRKNVSFTKRVFIALAIGIVFGMTIQYFYGTNS-------EITNETINWISILGDGY 76 Lyme disease spiroc... 1724006 1 METLLVVLHVFILFLLILGLFVMQKKHVSFSKRVFTALGLGIVFGFALQLIYGPTS-------NIVIQTADWFNIAGGGY 73 Bacillus subtilis 15791424 12 LSQAHTIATLAILCVVFYALKKMRDIKINFSLRMLFALLMGLGFGFALQYLANFPDaeeasniLWYSETKHWFAFVSSVF 91 Campylobacter jejuni 15831689 1 -MNFPLIANIVVFVVLLFALAQTRHKQWSLAKKVLVGLVMGVVFGLALHTIYGSDS-------QVLKDSVQWFNIVGNGY 72 Escherichia coli O1... 1175533 1 ----MLLVNLAIFIAFLLLLAQLYRKTEKLGQTVFIGLLLGLLFGAVLQSAFEK---------PLLDKTLDWINVVSNGY 67 Haemophilus influenzae 15602200 1 ----MVISNLIIFSLLLVLLRVIYTRTQKLGITVLIGLLLGVICGVLLQQFAAP---------MVIKPTLEWINLVGNGY 67 Pasteurella multocida 15926084 1 MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVFGVLLHLVYGTHS-------NVITSTSDWFNIVGQGY 73 Staphylococcus aure... 16764671 1 -MNFPLIANIAVFVILLFVLAQARHKQWSLAKKVLVGLVMGVVFGLALHTIYGADS-------QVLKDSIQWFNIVGNGY 72 Salmonella typhimur... 16764718 1 --MVVTLAYIALFLVFSWVILRINQKSDSLSKSVFIAIFLGAVIGLSLHFISAN----------HTKTIIEWYSIVGNGY 68 Salmonella typhimur... 16121976 2 GMNLPLVVNVLVFATLLLLLAQTRHKQWSLAKKVLIGLVLGVLFGSGLQWVYGADN-------PILKESITWFNIIGNGY 74 Yersinia pestis 15802140 1 -MNFPLIANIVVFVVLLFALAQTRHKQWSLAKKVLVGLVMGVVFGLALHTIYGSDS-------QVLKDSVQWFNIVGNGY 72 Escherichia coli O1... 9789824 1 -MNFPLIANIVVFVVLLFALAQTRHKQWSLAKKVLVGLVMGVVFGLALHTIYGSDS-------QVLKDSVQWFNIVGNGY 72 Escherichia coli
15641248 87 VGLLKMVIMPLVLVSMISAVVRLDKNGSLGKISSLTIGILLVTTAISALIGILITQAFGL-TAEGLVEGARETARIAALE 165 Vibrio cholerae 15595074 77 VRLLKMIIIPLIITSIISAIIKLTNSKDVGKMSLLVILTLVFTAGIAAIIGIFTALALGL-TAEGLQAGTIEILQSEKLQ 155 Lyme disease spiroc... 1724006 74 VKLLQMVVMPLVFISILGAFTKLKLTKNLGKISGLIIGILVATTAVAAAVGIASALSFDL-QAIQVDQGSTELSRGQELQ 152 Bacillus subtilis 15791424 92 VAFIKMLVVPLVSICIIKVIIEIDKNIKISSLLGISLFWILFSTAIAATLGIFLGYSFDLgSNFAIYEGDKQ---IREIQ 168 Campylobacter jejuni 15831689 73 VQLLQMIVMPLVFASILSAVARLHNASQLGKISFLTIGTLLFTTLIAALVGVLVTNLFGL-TAEGLVQGGAETARLNAIE 151 Escherichia coli O1... 1175533 68 VRLLQMIVMPLVFVSILSAIARINQTRSLGKVSVGVLSTLLITTAISAAIGIAMVHLFDV-SAAGLIVGDRELAAQGKVL 146 Haemophilus influenzae 15602200 68 VRLLQMIVMPLVFVSILSAITRLNQASALGKISLSVISVLLITTAIAAAIGIAMTYAFDL-TAEGLIAGERELAAQTHVA 146 Pasteurella multocida 15926084 74 VALLQMIVMPLIFISIVAAFTKIQIGEKFAKIGSLIFIFLIGTVTIAAIVGVVYALVFGL-DASTINLGNAEQARGSEIA 152 Staphylococcus aure... 16764671 73 VQLLQMIVMPLVFASILSAVARLHNASQLGKISFLTIGTLLFTTLIAALVGVLVTNLFGL-TAEGLVQGGAETARLNAIE 151 Salmonella typhimur... 16764718 69 VHLLKLVAIPLIFISILSAINKLENSAGIGKMSLTIVGCMLCLVMVAGFIGLLTAHVLGL-DASAFVHMP------SMLT 141 Salmonella typhimur... 16121976 75 VQLLQMIVMPLVFASILSAVAKLHNASSLGKISILTIGTLLFTTLIAALVGVFVTNLFGL-TAEGLIQGTQETARLSAIE 153 Yersinia pestis 15802140 73 VQLLQMIVMPLVFASILSAVARLHNASQLGKISFLTIGTLLFTTLIAALVGVLVTNLFGL-TAEGLVQGGAETARLNAIE 151 Escherichia coli O1... 9789824 73 VQLLQMIVMPLVFASILSAVARLHNASQLGKISFLTIGTLLFTTLIAALVGVLVTNLFGL-TAEGLVQGGAETARLNAIE 151 Escherichia coli
15641248 166 S-RASTVADLTIPQILLSFIPTNPFADLTGARSTSIIAVVIFGVLTGIAARKVIADK--QELETPIRTFVEAAQAIVMRL 242 Vibrio cholerae 15595074 156 K-GLEILNQTTITKKITDLIPQNIFEDFAGLRKNSTIGVVIFSAIIGIAALKTSIKK--PESIEFFKKIILTLQDIILGV 232 Lyme disease spiroc... 1724006 153 Q-KSEDMTAKTLPQQIVELLPGNPFLDFTGARPTSTIAVVIFAAFLGVAFLGVKHKQ--PEQAETFKKLVDAVYAIVMRV 229 Bacillus subtilis 15791424 169 T----------FSNIILGLIPSN---IITAINKENIIAIVIFSFFIGISAKKISKKEeyEQAFKSFHNFILTFYNIMMNM 235 Campylobacter jejuni 15831689 152 SiYVGKVSDLSVPQLVLSFIPKNPFADLTGANPTSIISVVIFAAFLGVAALKLLKDD--APKGERVLTAIDTLQSWVMKL 229 Escherichia coli O1... 1175533 147 D-KAGQVSNLTVPAMLVSFIPKNPFADLTGANPTSIISVVIFSALLGVAALSLGKED--QALGERIAQGVETLNKLVMRL 223 Haemophilus influenzae 15602200 147 G-RVEKVSELTIPSMLLSFIPKNPFLELTGANPTSIISVVIFAALLGIASLSLAKED--HALGERIAQGVDTLNKLIMRL 223 Pasteurella multocida 15926084 153 K-QAKDLTAHTLPQQILELLPKNPFLDFTGQRATSTIAVVIFASFIGFAYLRVARKQ--PDHGELLKRAIDAIYSLVMAI 229 Staphylococcus aure... 16764671 152 TsYVGKVADLSVPQLVLSFVPKNPFADLTGANPTSIISVVIFAAFLGVAALKLLKDD--APKGERVLVAIDTLQSWVMKL 229 Salmonella typhimur... 16764718 142 TeEVNKTAAVSIPQLVTSLIPTNIFLDLTGARSVSVIGIVIFTLIAGIALLKVKKEA--PEEGQKLSAGINAIQIWVMKM 219 Salmonella typhimur... 16121976 154 SnYLGKVADLTVPQLILSFIPKNPFADLTGASPTSIISIVIFATFLGIAALQLLKDD--VTKGQRVLAAIDTLQAWVMKL 231 Yersinia pestis 15802140 152 SiYVGKVSDLSVPQLVLSFIPKNPFADLTGANPTSIISVVIFAAFLGVAALKLLKDD--APKGERVLTAIDTLQSWVMKL 229 Escherichia coli O1... 9789824 152 SnYVGKVSDLSVPQLVLSFIPKNPFADLTGANPTSIISVVIFAAFLGVAALKLLKDD--APKGERVLAAIDTLQSWVMKL 229 Escherichia coli
15641248 243 VKMIMALTPYGIAALMAKVVATSSATDILNLLGFIVASYVAIALMFVVHGLLVAMVGVNPTRYFKNIWPVLTFAFTSRSS 322 Vibrio cholerae 15595074 233 VTLILKLTPYAILALMTKITATSEIKSIIKLGEFVIASYIAIGLTFLMHMTLIAINKLNPITFIKKIFPALSFAFISRSS 312 Lyme disease spiroc... 1724006 230 VTLILRLTPYGVLAIMTKTIATSDLDSILKLGMFVIASYAALITMFIIHLLLLTFSGLNPVIYLKKAVPVLVFAFTSRSS 309 Bacillus subtilis 15791424 236 TATVIRFMPYAVVCMMANVLLSNGFEAIKTAGLFIMLIYIAMFIMFGVHFLLLASQGLNPIKYAKKAFPVWLFAFSSRSS 315 Campylobacter jejuni 15831689 230 VRLVMQLTPYGVLALMTKVVAGSNLQDIIKLGSFVVASYLGLLIMFAVHGILLGINGVSPLKYFRKVWPVLTFAFTSRSS 309 Escherichia coli O1... 1175533 224 VRFVIRLTPYGVFALMIKMAATSKWADIVNLGNFIVASYAAIALMFVVHGILLFFVKVNPVDYYKKVLPTLSFAFTSRSS 303 Haemophilus influenzae 15602200 224 VRMVIRLTPYGVFALMLKMATTSKWADIVNLGTFIVASYAAIFLMFVVHGLLLAVFRVNPFTYFKKVMPTLSFAFTSRSS 303 Pasteurella multocida 15926084 230 VTFVLRLTPYGVLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYIIHLIILSLLGISPIRYVKKTLEVLIFAFTSRSS 309 Staphylococcus aure... 16764671 230 VRLVMQLTPYGVLALMTKVVAGSNLQDIIKLGSFVVASYLGLAIMFVVHGILLGVNGISPLKYFRKVWPVLTFAFTSRSS 309 Salmonella typhimur... 16764718 220 VRIVIALTPYGVMALMTTVFSSYRLEQFASLLGFIGACYIAIFMMFIVHAILLILSGNNPARYFRMVWPVLTFAFVSRSS 299 Salmonella typhimur... 16121976 232 VRLVMKLTPYGVLALMTKVVAGSNIQDIMKLGSFVVASYLGLAIMFVVHAVLLSLTGINPLKFFKKVWPVLTFAFTSRSS 311 Yersinia pestis 15802140 230 VRLVMQLTPYGVLALMTKVVAGSNLQDIIKLGSFVVASYLGLLIMFAVHGILLGINGVSPLKYFRKVWPVLTFAFTSRSS 309 Escherichia coli O1... 9789824 230 VRLVMQLTPYGVLALMTKVVAGSNLQDIIKLGSFVVASYLGLLIMFAVHGILLGINGVSPLKYFRKVWPVLTFAFTSRSS 309 Escherichia coli
15641248 323 AATIPLNVEAQITKLNVPPAIANLSASFGATIGQNGCAGIYPAMLAVMVAPTVGINPLDIHFIVSLIAMITISSFGIAGV 402 Vibrio cholerae 15595074 313 AATIPINIEIQTKNLGVSEGIANLSSSFGTSIGQNGCAALHPAMLAIMIAPTQGINPTDISFILTLIGLIIITSFGAAGA 392 Lyme disease spiroc... 1724006 310 AGALPLNIKTQ-RSMGVPEGIANFAGSFGLSIGQNGCAGIYPAMLAMMIAPTVGQNPFDPVFIITVIAVVAISSFGVAGV 388 Bacillus subtilis 15791424 316 LGTLPMTTSTLQNKFGVNSAIANFVASIGTTTGLNGCAGYFPALAAVFVAF-ATHTHIDFTFALMIVLVAVIGSLGIAGV 394 Campylobacter jejuni 15831689 310 AASIPLNVEAQTRRLGVPESIASFAASFGATIGQNGCAGLYPAMLAVMVAPTVGINPLDPMWIATLVGIVTVSSAGVAGV 389 Escherichia coli O1... 1175533 304 AATIPLNIETQTAKLGNNNVIANFAATFGATIGQNGCGGIYPAMLAVMVAPMVGIDPFSFSYILTLIFVVAISSFGIAGV 383 Haemophilus influenzae 15602200 304 AATLPLNIETQTNKLGNNNVIANFAATFGATIGQNGCAGIYPAMLAVMVAPTVGIDPFSLGYLATLILVVTISSLGIAGV 383 Pasteurella multocida 15926084 310 AGALPLNVQTQTRRLGVPEGIANFAATFGLSIGQNGCAGIYPAMLAIMVAP-VANVEIDLQFIVTLIAVVIISSFGVAGV 388 Staphylococcus aure... 16764671 310 AASIPLNVEAQTRRLGVPESIASFAASFGATIGQNGCAGLYPAMLAVMVAPTVGINPLDPVWIATLVGIVTVSSAGVAGV 389 Salmonella typhimur... 16764718 300 AASIPLAISAQ-EKFGVQSTIANISASFGSSMGQNGCAGIYPAIMVAMIAPTIGIDPLSLHFLAAMLPAIALGSIGVAGV 378 Salmonella typhimur... 16121976 312 AASIPLNVEAQTRRLGVPESIASFSASFGATIGQNGCAGLYPAMLAVMVAPTVGINPLDPVWIATLVGIVTISSAGVAGV 391 Yersinia pestis 15802140 310 AASIPLNVEAQTRRLGVPESIASFAASFGATIGQNGCAGLYPAMLAVMVAPTVGINPLDPMWIATLVGIVTVSSAGVAGV 389 Escherichia coli O1... 9789824 310 AASIPLNVEAQTRRLGVPESIASFAASFGATIGQNGCAGLYPAMLAVMVAPTVGINPLDPMWIATLVGIVTVSSAGVAGV 389 Escherichia coli
15641248 403 GGGATFAALIVLPAMGLP--VTIAALLISIEPLIDMARTALNVSGSMTAGTVTSRLLKETNEEPEPQTQQA 471 Vibrio cholerae 15595074 393 GGGATTASLMVLSAMNFP--VGLVGLVISVEPIIDMGRTAVNVGGSMLAGVISAKQLKQFNHNIYNQKELV 461 Lyme disease spirochete 1724006 389 GGGATFAALLVLSSLNMP--VALAGLLISIEPLIDMGRTALNVSGSMTSGLITSKVTKEIDQGAFHDQSRV 457 Bacillus subtilis 15791424 395 PGSATMAASIMLAGIGFGnnFVMLSLILAIDPIIDMARTASNVSGAMTSALCTAKNLKALDKEIYNS---- 461 Campylobacter jejuni 15831689 390 GGGATFAALIVLPAMGLP--VTLVALLISVEPLIDMGRTALNVSGSMTAGTLTSQWLKQTDKAILDSEDDA 458 Escherichia coli O157:H7 1175533 384 GGGATFAAIVVLSTLGLP--LELIGLLISIEPIIDMGRTALNVNGAMVAGTITDRLLNK------------ 440 Haemophilus influenzae 15602200 384 GGGATFAAIVVLSTLNLP--LALVGLLISIEPLIDMGRTALNVNGSMVAGTITNQLLDKKTEKV------- 445 Pasteurella multocida 15926084 389 GGGATFASILVLSTLNLP--VALAGVLISVEPLIDMGRTALNVNDSMLAGTGTAKLTKHWDKDTFESNDNA 457 Staphylococcus aureus subsp.... 16764671 390 GGGATFAALIVLPAMGLP--VTLVALLISVEPLIDMGRTALNVSGSMTAGTLTSQWLKQTDKTILDSEEDA 458 Salmonella typhimurium LT2 16764718 379 GGGGTFAALIVLSTLNFP--VALVGIFIAIEPIVDMARTALNVNGSMMSGVLANRILNNHTADDMPAVIDR 447 Salmonella typhimurium LT2 16121976 392 GGGATFAALIVLPALGLP--VTLVALLISVEPLIDMGRTALNVNGSMTAGTITSQLMKQTDKNILNNEDDD 460 Yersinia pestis 15802140 390 GGGATFAALIVLPAMGLP--VTLVALLISVEPLIDMGRTALNVSGSMTAGTLTSQWLKQTDKAILDSEDDA 458 Escherichia coli O157:H7 EDL933 9789824 390 GGGATFAALIVLPAMGLP--VTLVALLISVEPLIDMGRTALNVSGSMTAGTLTSQWLKQTDKAILDSEDDA 458 Escherichia coli
Jiyao W et al.(2023). "The conserved domain database in 2023.",