Conserved Protein Domain Family
DUF2400
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pfam09674: DUF2400 (this model, PSSM-Id:401565 is obsolete and has been replaced by 430745)
Protein of unknown function (DUF2400)
Members of this uncharacterized protein family are found sporadically, so far only among spirochetes, epsilon and delta proteobacteria, and Bacteroides. The function is unknown and its gene neighborhoods show little conservation.
Links
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Statistics
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PSSM-Id: 401565
Aligned: 127 rows
Threshold Bit Score: 204.295
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_013667867       24 DPICIPHQFSVKQDVEIMGFFAAVLAWGQRKTIINKCRELidrmdgkpyAFII--GHE-PDDLKG-LLG-F---K--HRT 93  Sphingobac...
tigr:CHAB381_0721  26 DPLQVAKVQNN----DIIALICALFAYGNAGLIVKFLKKL---------DFDLlkKSDeE------IKKsMnalK--YRF 84  Campylobac...
Q0P8E8             29 DPLQIAKIHND----EFIALICALFAYGNAKNIVNFLKKL---------DFSLlnLQEkQ------IKKeLknlK--YRF 87  Campylobac...
EES89271           24 DPLGVARQFMS----DKVALFCALFAYGNARAIVRFLESC---------NLYFldQASyKSHHNLhLNEiPyctNkpYRF 90  Helicobact...
Q7MSP2             29 DPLLVAQKTKS----DLGALICALFSYGSAKQIVTFLETL---------DFSLlaQTPqSIQNAPfg---------vYRF 86  Wolinella ...
BAM33333           32 DPLLIARIYKEDSHFAEIALICALLSYGNAKMIVKLLQSL---------DFGLltRG---------IDRiQkanFphYRF 93  Helicobact...
Q7VGN4             27 DPLLVAKKYQHTPYFAEIALICALLSYGNAKAIVQMLQKL---------DFSLlhSRTkIRNATFp----------yYRF 87  Helicobact...
jgi:Nitsa_0828     29 DPLLVASRYRD----ERIALVCALFGYGNAGLIVRFLESL---------DFSLldADEeT------IRReLsgmY--YRF 87  Nitratifra...
BAF69964           26 DPLLIASRYKN----EKIALACALFSYGSAKQIVSFLDRL---------DFSLlhENPlDQKKFPy-----------YRF 81  Nitratirup...
WP_012856918       29 DPLMIASLYAD----EFSALICALFSYGNAKAIVAFLQRL---------DFNLldVEEsM------ISQaLqsyR--YRF 87  Sulfurospi...

WP_013667867       94 FNDTDLLYFVSFFRAHYERFNS--LEDAFLPssmssefredflmegqeeAVSSQEMssnvcyqtelirpnlkvEDALNRF 171 Sphingobac...
tigr:CHAB381_0721  85 ENSRDTAEIFITLKRFSQNF-S--IEEEILKg-----------------mQNSAQI-----------------IDGINNL 127 Campylobac...
Q0P8E8             88 QNEKDIQEIFITLSRLKNEI-S--LYELFYQa-----------------yQERENT-----------------TDAILAF 130 Campylobac...
EES89271           91 QNQDEIQDFFESLLMSGD------LYEIFYRa------------------yKKDSL-----------------LKGIEAL 129 Helicobact...
Q7MSP2             87 QNSEDVRQLFLALSTLDDSPQA--LRSIFLEg------------------hKKGGI-----------------LEGIKTM 129 Wolinella ...
BAM33333           94 QTSKDIQGLFMLVKILLE---SsgLLQCFMQgyesyphtksesqwsksnNPNHAKI-----------------LSGIYHC 153 Helicobact...
Q7VGN4             88 QTSADIQNIFESVACMLE-NGG--LLTYFLKayknppah--falwhqsaNKNHARI-----------------LYSIYHC 145 Helicobact...
jgi:Nitsa_0828     88 QNSVDLTALFIALRRLGRER-S--IEEIVRRg-----------------yERRGEI-----------------RDGLWEL 130 Nitratifra...
BAF69964           82 QTSQDVANLFLALHSIDS------LEDIFMDa-----------------yKKNKNV-----------------MDGISSV 121 Nitratirup...
WP_012856918       88 QTPEDIQALFITLNRIKKSSLS--LEKFFLPa-----------------yQKHHNV-----------------MDGLGAL 131 Sulfurospi...

WP_013667867      172 RAYFFSlp--dyPTRTRK---HISSP------------AQKSTCKRLNMFLRWMVRNDlrGVDFGIWKR-IRMSELICPC 233 Sphingobac...
tigr:CHAB381_0721 128 IKTIYSl----nDYRSQGyefFFGHTfed---------epKSPYKRYNMFLRWMVRDS--DIDLGLFSK-IDKKDLLIPL 191 Campylobac...
Q0P8E8            131 MQKIKTl----nSYSSYGydfFFGKIwqn---------tpTSPLKRYNMYLRWMVRKD--ELDLGLFTK-IHTKDLLIPL 194 Campylobac...
EES89271          130 QNYLYSn----lKKTTKSlefLIGKS------------QSNSPLKRWNMFLRWMVRKD--CVDLGLWEG-IKRSDLILPL 190 Helicobact...
Q7MSP2            130 QRAILErs---gGYQSSGfrfLIGNPe-----------AHQSPLKRWNMFLRWMIRKD--CLDLGWWEGvILKSELILPL 193 Wolinella ...
BAM33333          154 IDTLYLlakthkIPITQGlrfLLGSShstylaqhhtipHNASCLKRWNMLLRWLIRKD--RLDVGTWAShLQSSNLILPL 231 Helicobact...
Q7VGN4            146 IDALYSfl--ckDTKSKGlhfAFGTSysvhintygafpTGACALKRWNMLLRWLVRKD--EIDIGCWQEhIPTSHLILPL 221 Helicobact...
jgi:Nitsa_0828    131 IGELERl----sGHQSRGyrfLIGRVpkd--------peRCAPFKRYMMYFRWIVRRD--ALDMGLWSG-IDPADLIIPL 195 Nitratifra...
BAF69964          122 IRRIYEa----nSYRSRGyrfLIGKIppp------nkmKEIGAYKRWHMFLRWMVRKD--HLDMGLWNE-VDPSDLIIPL 188 Nitratirup...
WP_012856918      132 IEILYDv----nPYRSRGyqfLLGTIpsa---------qpTSPYKRWHMYLRWMVRKD--NLDLGLWKG-VDTKDLLMPL 195 Sulfurospi...

WP_013667867      234 DVHVERVARHLGLITRKQTDWNTAVELTDNLRLLDANDPVKYDFALFGLGVE 285 Sphingobacterium sp. 21
tigr:CHAB381_0721 192 DVHTHRVCLALGLCKRKSYDFKSVMQITQNLREFDANDPIKYDFALYRLGQS 243 Campylobacter hominis ATCC BAA-381
Q0P8E8            195 DTHAHKISLTLGLLKRKIYDYKSVLELTQNLKKLDANDPIKYDFALYRLGQS 246 Campylobacter jejuni
EES89271          191 DTHTFRVSQRLGILKRKSYDLKAALEVSEFLKKLDLNDPIKYDFALYRIGQl 242 Helicobacter canadensis MIT 98-5491
Q7MSP2            194 DTHTFALCKKLKIIQRQSYDLKAAIEATEFLKKLDPHDPIKYDFALYRLGQE 245 Wolinella succinogenes
BAM33333          232 DTHTFRICGKLSILQRKSYDLSAALEATDTLALFNPKDPIAYDFALYRLGQN 283 Helicobacter cinaedi CCUG 18818 = ATCC...
Q7VGN4            222 DTHTFKLCLKLKILKRKSYDLQSALQATDTLCMLNPNDPISYDFALYRIGQS 273 Helicobacter hepaticus
jgi:Nitsa_0828    196 DTHTHTVSLRLGLLKRKSYDMKAALELTETLRGFDPADPVKYDFALYRIGQE 247 Nitratifractor salsuginis DSM 16511
BAF69964          189 DTHTFHIGHKLGLLDRKTQDLYAAYLLTQSLKKFDPEDPLKYDFVLYRLGQE 240 Nitratiruptor sp. SB155-2
WP_012856918      196 DTHTFTLGKKLGLIQRKTYDFKAVLELSSALKKIDPSDPIKYDFALYRLGQE 247 Sulfurospirillum deleyianum
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