4FUS_A                 28 YNERFMEMWNKIHDPANGYF-------SA-DGGPYHSVETLIVEAPDHGHESTSEAYSYFLLLEAYYGKVTGDWSKLRNA 99   Hahel...
A3DH67                 40 YKDLFLELYGKIKDPKNGYF-------SPdEGIPYHSIETLIVEAPDYGHVTTSEAFSYYVWLEAMYGNLTGNWSGVETA 112  Aceti...
jgi:Clocl_4007         31 FKDRFNYMYNKIHDPANGYF-------DS-EGIPYHSVETLCVEAPDYGHESTSEAASYYAWLEAVNGKLNGKWSGLTEA 102 
CDM70442                9 YKDRFIDLWEKIHDEKNGYFkkfdvdgKS-LKVPYHSIETLICEAPDYGHETTSEAFSYYIWLEAMYGKLTGDFDSFKDS 87  
goetting:Cspa_c18580   45 YQQRFMTMWGKIHDSKNGYFknftdggTT-LKVPYHSVETFMCEAPDYGHETTSEAYSYYMWLEAMYGKFTGNWNEFKNA 123 
jgi:Clole_3668         42 YEQRFLDLYEDIKDNSNGYF-------SP-QGVPYHSIETLMVEAPDHGHESTSETASYYVWLEAMNGKFTGDFSGLKEA 113 
Q97KK7                 49 YTQRFETMYNKMHDANNGYF-------SK-DGVPYHSVETFMVEAPDYGHETTSEAFSYYMWLEAMQGKITGNFSGVNTA 120  Clost...
jgi:Clocel_2823        41 YVQHFKDMYAKIHNANNGYF-------SD-EGIPYHAVETLMVEAPDYGHETTSEAFSYYMWLEAMNAKLTGDFSGFKKA 112 
1FAE_A                  9 YQDRFESMYSKIKDPANGYF-------SE-QGIPYHSIETLMVEAPDYGHVTTSEAMSYYMWLEAMHGRFSGDFTGFDKS 80   Rumin...
P50900                 40 YKQRFLELWEELHDPSNGYF-------SS-HGIPYHAVETLIVEAPDYGHLTTSEAMSYYLWLEALYGKFTGDFSYFMKA 111  Therm...

4FUS_A                100 WAKMEEHIIPTQEMQP--TNNFYNPSKPASYAAEHAQPSGYPSQLEF-GVPVGEDPISAKLAQTYGSWdVYGMHWLLDMD 176  Hahel...
A3DH67                113 WKVMEDWIIPDSTEQP--GMSSYNPNSPATYADEYEDPSYYPSELKFdTVRVGSDPVHNDLVSAYGPN-MYLMHWLMDVD 189  Aceti...
jgi:Clocl_4007        103 WNVVEKYFIPSESIQK--GMNRYNPSSPAGYADEFPLPDDYPAQIQS-NVTVGQDPIHQELVSAYNTYaMYGMHWLVDVD 179 
CDM70442               88 WASTEAFIIPHGKGQN--GIEAYNPSSPATLANEYPTPDKYPTKLQF-GASVGQDPINYELKNAYGSSeMYGMHWLLDVD 164 
goetting:Cspa_c18580  124 WDSADKYIIPHGQDQA--GMNAYNPNSPATLANEYPTINKYPSKLLF-GTPVGKDPINNELKNAYGSGeMYGMHWLLDVD 200 
jgi:Clole_3668        114 WNVIEKYYIPTDLDQP--GQTDYNPNSPATYASEYPLPDYYPSQLQF-GLPVGTDPIANELKSTYGTSkIYGMHWLIDGD 190 
Q97KK7                121 WDTAEKYMIPSHQDQP--GMDRYNASSPATYSPEWEDPSKYPSRMDQ-GAAKGQDPISDELKSAYGTSdMYGMHWLMDVD 197  Clost...
jgi:Clocel_2823       113 WDVTEKYIIPGETDQPsaSMSNYDPNKPATYAAEHPDPSMYPSQLQF-GAAVGKDPLYNELKSTYGTSqVYGMHWLLDVD 191 
1FAE_A                 81 WSVTEQYLIPTEKDQPntSMSRYDANKPATYAPEFQDPSKYPSPLDT-SQPVGRDPINSQLTSAYGTSmLYGMHWILDVD 159  Rumin...
P50900                112 WETIEKYMIPTEQDQPnrSMAGYNPAKPATYAPEWEEPSMYPSQLDF-SAPVGIDPIYNELVSTYGTNtIYGMHWLLDVD 190  Therm...

4FUS_A                177 NIYGYgnlgdGV-STPSYINTFQRGEQESVWETVTHPSWESFKWGGPNGFLPLFTKDNNY-SRQWRYTNAPDADARAVQV 254  Hahel...
A3DH67                190 NWYGF-----GTgTRATFINTFQRGEQESTWETIPHPSIEEFKYGGPNGFLDLFTKDRSY-AKQWRYTNAPDAEGRAIQA 263  Aceti...
jgi:Clocl_4007        180 NWYGY-----GTgTNCTFINTYQRGEQESVFETVPHPSIEEFKYGGRQGFSDLFTAGET--QPKWAFTIASDADGRLIQV 252 
CDM70442              165 NWYGY-----GDdTAPVYINTFQRGPMESVWRTIPHPSIEEFKWGGQNGFLDLFTGDNSY-AKQWRYTIAPDADARAIQA 238 
goetting:Cspa_c18580  201 NWYGYgnrgdANsNAPAYINTFQRGSEESVWKTVPQPSYETFKWGGKNGYLDLFTGDNNY-SKQWRYTDAPDADARAIQA 279 
jgi:Clole_3668        191 NFYGYgrrgdGV-SAPSYINTFQRGEQESTWETIPQPSWEDFKWGGKSGFLPFFTGDANY-SKQWRYTNAPDADARLVQA 268 
Q97KK7                198 NWYGFgnhedGT-SKNVYINTYQRGEQESVFETVPQPCWDAFKYGGKNGYLDLFTGDNSY-AKQAKYTDAPDADARAIQA 275  Clost...
jgi:Clocel_2823       192 NWYGFg---gATsTSPVYINTFQRGVQESCWETVPQPCKDEMKYGGRNGFLDLFTGDSQY-ATQFKYTNAPDADARAVQA 267 
1FAE_A                160 NWYGFgaradGT-SKPSYINTFQRGEQESTWETIPQPCWDEHKFGGQYGFLDLFTKDTGTpAKQFKYTNAPDADARAVQA 238  Rumin...
P50900                191 NWYGFgrradRI-SSPAYINTFQRGSQESVWETIPQPCWDDLTIGGRNGFLDLFVGDSQY-SAQFKYTNAPDADARAIQA 268  Therm...

4FUS_A                255 MYWAYQWIKEQGKdpEQEVPGLMAKAAKMGDYLRLAMFDKYFKKMGtqDKnAQGGKGYESAHYLMSWYYAWGGAADAnaG 334  Hahel...
A3DH67                264 VYWANKWAKEQGK--GSAVASVVSKAAKMGDFLRNDMFDKYFMKIG--AQdKTPATGYDSAHYLMAWYTAWGGGIGA--S 337  Aceti...
jgi:Clocl_4007        253 QYWANKWAKEQGQ----NLSTLNAKAAKLGDYLRYSMFDKYFMKIG--AQgKTPASGYDSCHYLLAWYYAWGGAIAG--D 324 
CDM70442              239 TYWADAWAKEQGE----NVDEEVSKSSKMGDYLRYSMFDKYFKNIGv-GSdSPSNT---SQHYLLSWYYSWGGGLEA--N 308 
goetting:Cspa_c18580  280 TYWADEWAKTQGK----DVSQYVSKASKMGDYLRYSMFDKYFKPIGv-GA--DQQTEASGQHYLLSWYYAWGGGAGG--D 350 
jgi:Clole_3668        269 MYWAKDWAEEQGQ----NIDTYVAKASKMGDYLRYAMFDKYFMKIG--AQgKTPGQGYEAAHYLMSWYYAWGGGLDA--N 340 
Q97KK7                276 TYEAAQAAKEDGV----DLSSIVGKASKMGDYLRYAMFDKYFRKIGn-ST--QAGNGKDSMHYLLSWYYAWGGSQNN--D 346  Clost...
jgi:Clocel_2823       268 TYYAQLAAKEWGV----DISSYVAKSTKMGDFLRYSFFDKYFRKVGn-ST--QAGTGYDSAQYLLNWYYAWGGGISS--N 338 
1FAE_A                239 TYWADQWAKEQGK----SVSTSVGKATKMGDYLRYSFFDKYFRKIGq-PS--QAGTGYDAAHYLLSWYYAWGGGIDS--T 309  Rumin...
P50900                269 TYWANQWAKEHGV----NLSQYVKKASRMGDYLRYAMFDKYFRKIGd-SK--QAGTGYDAAHYLLSWYYAWGGGITA--D 339  Therm...

4FUS_A                335 WAFRIGSSXVHFGYQNPIAAMALSEFDPLKPRTPGATEDWATGLKRSMEFYTWLQSAEGGIAGGATNSW---DGSYKPHP 411  Hahel...
A3DH67                338 WAWKIGCSHAHFGYQNPFQGWVSATQSDFAPKSSNGKRDWTTSYKRQLEFYQWLQSAEGGIAGGATNSW---NGRYEKYP 414  Aceti...
jgi:Clocl_4007        325 WSWKIGCSHVHWGYQAPLAAYALANDPDLKPKSANGAKDWNSSFKRQVELYAWLQSAEGAIAGGVTNSV---GGQYKSYN 401 
CDM70442              309 WAWKIGCSHNHFGYQNPMTAWILTNVDNFKPKSSNGVSDWKKSLERQLEFYQWLQSSEGAIAGGATNSYmteDGSYQKYP 388 
goetting:Cspa_c18580  351 WSWKIGCSHNHFGYQNPMTAWVMSKDADFKPKSSGGASDWNKSLDRQLELYQWLQSSEGGIAGGATNSLttdAGSYQKYP 430 
jgi:Clole_3668        341 WSWRIGSSHNHFGYQSPMAAWVLSTDSDMIPKSPNAKRDWAKSLDRQIEFYQWLQSAEGAIAGGATNSY---GGSYEKYP 417 
Q97KK7                347 WSWKIGCSHSHFGYQNPLTAWVLSTDSQFKPKSATGATDWAKSLTTQVDFYQWLQSSEGAIAGGASNSN---HGRYEAWP 423  Clost...
jgi:Clocel_2823       339 WSWRIGSSHNHFGYQNPMAAWILSNTSDFKPKSPNAATDWNNSLKRQIEFYQWLQSAEGGIAGGASNSN---GGSYQAWP 415 
1FAE_A                310 WSWIIGSSHNHFGYQNPFAAWVLSTDANFKPKSSNGASDWAKSLDRQLEFYQWLQSAEGAIAGGATNSW---NGRYEAVP 386  Rumin...
P50900                340 WAWIIGCSHVHAGYQNPMTAWILANDPEFKPESPNGANDWAKSLERQLEFYQWLQSAEGAIAGGATNSY---KGRYETLP 416  Therm...

4FUS_A                412 QdrADATFYGMVYDENPVYHDPGSGTWFGWQAWSMQRVAEYYYLKGDAQAKQLMDKWAPWVLSNINWLEDg--SFEIPAT 489  Hahel...
A3DH67                415 A--GTSTFYGMAYVPHPVYADPGSNQWFGFQAWSMQRVMEYYLETGDSSVKNLIKKWVDWVMSEIKLYDDg--TFAIPSD 490  Aceti...
jgi:Clocl_4007        402 ---GASTFYDMAYTYAPVYADPPSNNWFGMQAWSMQRMCEVYYETGDSLAKEICDKWVAWAESVCEADIEa-gTWKIPAT 477 
CDM70442              389 S--DLPTFYGMVYDWKPVYHDPPSNNWFGMQGWSMERVAEYLYETGDKKAMDIMKKWVEWIKSVVKLYENg--DFEIPDR 464 
goetting:Cspa_c18580  431 E--GTPTFYGMAYDWQPVYHDPPSNNWFGMQTWSMQRVAELYYKTGDKRAQAVLDKWTKWVKSVVKLNDDg--TYAIPNN 506 
jgi:Clole_3668        418 A--GTSTFYGMAYDAHPVYEDPGSNQWFGMQGWSMQRMAEYYYESGDSRVKGLLDRWAAWAKSEIQLYDDg--TFAVPST 493 
Q97KK7                424 E--GTATFDGMGYQEEPVYHDPGSNTWFGMQSWSMQRMAQYYYQSKDPKAKALLDKWVKWIKSVVKVNPNgagTFEVPSK 501  Clost...
jgi:Clocel_2823       416 A--GTATFYGMGYTPHPVYEDPGSNEWFGMQAWSMQRVAEYYYSSKDPAAKSLLDKWAKWACANVQFDDAa-kKFKIPAK 492 
1FAE_A                387 S--GTSTFYGMGYVENPVYADPGSNTWFGMQVWSMQRVAELYYKTGDARAKKLLDKWAKWINGEIKFNADg--TFQIPST 462  Rumin...
P50900                417 A--GISTFYGMAYEEHPVYLDPGSNTWFGFQAWTMQRVAEYYYLTGDTRAEQLLDKWVDWIKSVVRLNSDg--TFEIPGN 492  Therm...

4FUS_A                490 LEWTGKPEKWDPAn-PKANTNLHVSVVDHGQDLGIAAGVAKALMFYAAAa-EkydtpQNE----AK--EASKKLLDAMWT 561  Hahel...
A3DH67                491 LEWSGQPDTWTGT--YTGNPNLHVRVTSYGTDLGVAGSLANALATYAAAteRwegklDTK----AR--DMAAELVNRAWY 562  Aceti...
jgi:Clocl_4007        478 LEWSGQPDTWRGT--KPSNNNLHCKVVNYGNDIGITGSLANAFLFYDQAtqRwn--gNTTlgkkAA--DKALAMLQVVWD 551 
CDM70442              465 LEWSGNPDNWTGS--YTGNPNLHVKVASYGKDLGITAAVAQTLLYYSAAt-KkygtfDKD----AK--DLSKELLDRMWN 535 
goetting:Cspa_c18580  507 LTWSGQPDTWNGT--YTGNPGLHVDVKDYSQDVGVTSSLANTLTYYAAAs-NkystfDKD----SA--KLAKELLDRMWK 577 
jgi:Clole_3668        494 LQWSGQPDTWTGS--YTGNKNLHVDVINYGTDLGTVASMANTLTFYAAAt-KkyspeQDY----QSyvDITKEVLDRMWT 566 
Q97KK7                502 LSWTGQPDTWTGS--YTGNPNLHVNVDSYTTDIGTSSSTADALAYYAAAt-G-----DKD----SQ--ALSKTILDDIWK 567  Clost...
jgi:Clocel_2823       493 LVWTGQPDTWTGS--YTGNSNLHVKVEAYGEDLGVAGSLSNALSYYAKAleSstdaaDKVayntAK--ETSRKILDYLWA 568 
1FAE_A                463 IDWEGQPDTWNPTqgYTGNANLHVKVVNYGTDLGCASSLANTLTYYAAKs-G-----DET----SR--QNAQKLLDAMWN 530  Rumin...
P50900                493 LEWSGQPDTWTGT--YTGNPNLHVSVVSYGTDLGAAGSLANALLYYAKTs-G-----DDE----AR--NLAKELLDRMWN 558  Therm...

4FUS_A                562 HF--KTPKGLAAPEKRGDYARFFD-KVYVPGEFNGSMANGDAINSESTFLSMRSFYLDDPMFKQVEDALNSGEDPVFTYH 638  Hahel...
A3DH67                563 NFycSEGKGVVTEEARADYKRFFEqEVYVPAGWSGTMPNGDKIQPGIKFIDIRTKYRQDPYYDIVYQAYLRGEAPVLNYH 642  Aceti...
jgi:Clocl_4007        552 TC--RDQYGVGVKETNESLNRIFTqEVFIPAGWTGKMPNGDVIQQGVKFIDIRSKYKDDPWYEGLKKQAEQGIPFEYTLH 629 
CDM70442              536 LY--QDDKGYSAEESKEDYSKFFEtEVYVPSGWSGKMANGDEIKSGIKFLDIRSKYKNDPDFDKISDAYKNNEAPVFKYH 613 
goetting:Cspa_c18580  578 LD--QDSKGLSVEEERADYSKIFDtKVYIPDGWSGKMPNGDVIKPGVSFLDIRSKYKQDPDFAKVEEAYKEGKAPVFKYH 655 
jgi:Clole_3668        567 LY--RDDKGVAAPEVRADYKRFFEqEVYVPSNYTGKMANGDEIVPGVTFIELRSKYKNDPDFARLEQAYKNGEDFEITYH 644 
Q97KK7                568 NY--QDAKGVSAPE-QMDYSRVFNqEVYIPQGWTGTMPNGDVIKSGNKFIDIRSQYKNDPDYARVKSDVEAGKSSTFNYH 644  Clost...
jgi:Clocel_2823       569 SY--QDDKGIAVTETRNDFKRFNQ-SVYIPSGWTGKMPNGDVIQSGATFLSIRSKYKQDPSWPKVEAALANGTGVDMTYH 645 
1FAE_A                531 NY--SDSKGISTVEQRGDYHRFLDqEVFVPAGWTGKMPNGDVIKSGVKFIDIRSKYKQDPEWQTMVAALQAGQVPTQRLH 608  Rumin...
P50900                559 LY--RDDKGLSAPETREDYVRFFEqEVYVPQGWSGTMPNGDRIEPGVTFLDIRSKYLNDPDYPKLQQAYNEGKAPVFNYH 636  Therm...

4FUS_A                639 RFWAQTEAATAYANYAALF 657  Hahella chejuensis KCTC 2396
A3DH67                643 RFWHEVDLAVAMGVLATYF 661  Acetivibrio thermocellus ATCC 27405
jgi:Clocl_4007        630 RFWHQVDYAVALGIAEifg 648 
CDM70442              614 RFWTEASIAIANGVYAILs 632 
goetting:Cspa_c18580  656 RFWAQSEAAIANGAYSILs 674 
jgi:Clole_3668        645 RFWAQAEIAIANGTMAMLF 663 
Q97KK7                645 RFWAESEYAIANANYGTLF 663  Clostridium acetobutylicum
jgi:Clocel_2823       646 RFWGQSDIAIAFGTYGTLF 664 
1FAE_A                609 RFWAQSEFAVANGVYAILF 627  Ruminiclostridium cellulolyticum
P50900                637 RFWAQCDIAIANGLYSILF 655  Thermoclostridium stercorarium subsp. stercorarium DSM 8532