6NQ3


Conserved Protein Domain Family
Mtf2_C
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pfam14061: Mtf2_C (this model, PSSM-Id:404871 is obsolete and has been replaced by 464077)
Polycomb-like MTF2 factor 2
Mammalian Polycomb-like gene MTF2/PCL2 forms a complex with Polycomb repressive complex-2 (PRC2) and collaborates with PRC1 to achieve repression of Hox gene expression. The human MTF2 gene is expressed in three splicing variants, each of them contains the short C-terminal domain defined here. The domain is subject to structure determination by the Joint Center of Structural Genomics.
Links
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Statistics
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PSSM-Id: 404871
Aligned: 11 rows
Threshold Bit Score: 80.5023
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6NQ3_C         35 SLSHLKSSITNYFGAA-GRLACGEKYQVLARR-VTPEGK---VQYLVEWEGTT 82  
XP_003431418  172 SLSHLKSSITNYFGAA-GRLACGEKYQVLARR-VTPEGK---VQYLVEWEGTT 219  platypus
Q02395        544 QLNHLKNSITSYFGAA-GRIACGEKYRVLARR-VTLDGK---VQYLVEWEGAT 591  house mouse
XP_016838546  823 SMDDLKSSVNMYFGAA-NRIASGEKFMVRAKR-SGPNGR---AQYLIEWEGPT 870  jewel wasp
EEZ97202      669 NMDDLKSSVNIYFGAA-NRIAAGERFAVKAKR-VGPSGK---LEFLIEWEGPG 716  red flour beetle
Q16TK7        202 VGTDLQSSLNLYFGAA-HRILSGERFVIKGRR-VSVSGK---VQYLIEWEGCP 249  yellow fever mosquito
EDW32276      986 SILDLKKSVNKYFGGAmNRIDSGEPFAIRAKR-RTGNGQ---VQYLVEWGGDA 1034 Drosophila persimilis
XP_018670183  648 AHEDLRKNIARYFGPE-GRIACGERYRVLAKRqVSMKGNpphTEYLIEWEGYT 699  vase tunicate
XP_002588203  339 SMEHLRASVNSYFGAE-GRLACGEKYTVLARR-VTPDGK---VQYLVQWEGFT 386  Florida lancelet
XP_002062814 1040 SMLDLKQSVNKYFGGAiNRIDAGESFAIRAKR-RMGNGQ---VQYLVEWTNGN 1088 Drosophila willistoni
XP_011617916  512 DSSHLHSSISSYFGIA-GRLTNGERYQVLARR-ITPQGT---VQYLLEWEGAT 559  torafugu
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