5A9Q


Conserved Protein Domain Family
Nup84_Nup100
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pfam04121: Nup84_Nup100 (this model, PSSM-Id:397996 is obsolete and has been replaced by 461184)
Nuclear pore protein 84 / 107
Nup84p forms a complex with five proteins, of which Nup120p, Nup85p, Sec13p, and a Sec13p homologs. This Nup84p complex in conjunction with Sec13-type proteins is required for correct nuclear pore biogenesis.
Links
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Statistics
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PSSM-Id: 397996
Aligned: 112 rows
Threshold Bit Score: 469.073
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
5A9Q_4       210 WLLQQEMVTWRLLASLYRDRI-QS-----ALeeESVFAVTAVn--ASEKTVVEALFQRDSLVRQSQLVVDWLESIAkdei 281 
EME48757     130 RQWQQEVDIWELFRIMLELHHnPDvrsmqQEkeDKLRSLGEVhryTSEQDIWKRFLVHDDLAKERAMVKRWLEETA---- 205  Dothistroma se...
XP_016765165 171 RKWQQEADIWDLFRLMLELHHhPDqraqkRQrdDRLRELGDVhryTSEAALWDRFLLTDDVAKERHLVKQWLEQSA---- 246  Sphaerulina mu...
XP_007920136 161 RQWQQEADIWDLFHIILDVHHnPQrs--sQFrqQNPSTSDAVhryTTEKQLWDRFLLTDDLAHERSLVKTWLEQSA---- 234  Pseudocercospo...
CCX06581     179 KYWELEHQTWELFGALISHRL-DA-----ENymTQDVPPSLAnkyAADSQIRNHFFTTDPSFRELTIVLEWLRRYApapt 252  Pyronema ompha...
EGX49966     164 AFYKMEYETWNLVSRLLPERGv-----------EYTHTLRTVseyESNEVLRRQLLDESPTFRELNIIRDWLRSIAphpe 232  Arthrobotrys o...
EPS42823     160 EFYKMEGETWDLVARLVPGRNi-----------DLSGTSRHVaeyESNENLRRQLLKESSVFRELNLIRDWLRSIApepe 228  Dactylellina h...
CCJ29617      89 EQWDLECKTWDLIQRLYSHRV------------QKSHELPNIheySSNVILEEAFYIQTPEAMENTIILNWLKDIFpepp 156  Pneumocystis j...
XP_002175266 102 EQWDLEMRTWDLVQRLYLLRS------------TGKVPVVPAhrfSSRAIWEEKFYSENIQASENNLVLNWLRDSAsspa 169  Schizosaccharo...
Q10331       123 ELWDLESRTWDLIQRLYSFRL------------SEQQGHIQShafSSRAVLEEEYYSQNPEAFENNIVFNWARDNSsdpp 190  Schizosaccharo...

5A9Q_4       282 GEFsd--nI---EF--YA-K-----SVYWENTLHTLkqrQLTS----------------YVGSV-Rp------LVT-ELD 324 
EME48757     206 EHQesdipGimeELekQAgVgkgmwLHGVVHTRATIkgeKRLRpwpn---------apaAALPHiTraddaepLVT-QLD 275  Dothistroma se...
XP_016765165 247 NHQasevaGiveELesKAgRgrglwSNGWMHTRERIkheKRLRawpe---------pdaMPLPHlKrsdnpeaLVT-SLD 316  Sphaerulina mu...
XP_007920136 235 EHQasdlnGiveELeaKAgRgkglwHHGWMHTREHIkheKRMRawpa---------pdaDPLPQlRstdkaelLVT-SLD 304  Pseudocercospo...
CCX06581     253 ADDieedaLyrgD-------------RGWMYTKEKIkgcKRLQ----------------GRGLSlGneaeldkVVT-ELD 302  Pyronema ompha...
EGX49966     233 IPNed-------------mEddevmGSGHMYTLNALkqyKRDNmdpeefvtkgpnaqfeYPERGiPsaenksqLITtELD 299  Arthrobotrys o...
EPS42823     229 IPNed-------------aTdeeamASGHMYTLNALkhyKQDNmdpmefvqkgpnarfeYPERGiAspddknqLINtEMD 295  Dactylellina h...
CCJ29617     157 LLEis--------------------gKKWLYTRESIrmkRLQRktlk-----------------------edqLID-ELD 192  Pneumocystis j...
XP_002175266 170 AIElr--------------------gNRWFYTREAIktrSRTIssfge---------------------ksnvYVS-SLD 207  Schizosaccharo...
Q10331       191 SIEir--------------------gNRWFYTREDIkmkNRGGsrfss--------------------nisgtIVS-NLD 229  Schizosaccharo...

5A9Q_4       325 PDAPIRQKMPLDDLDREDEVRLLKYLFTLIRAGM-TEEAQRLCKRCGQAWRAATLEGWKLYHDPNVngg---------te 394 
EME48757     276 PDAASRQGRVVERKDAFFEQVMWIACWEMLRRGKsWQEVTDWCKTRNESWRALSMGK----------------------- 332  Dothistroma se...
XP_016765165 317 PDAATRQDRSLERPDAYFERATWITCWEMLRRGHsWEQVSEWCEQRNESWRAIVIGKs---------------------- 374  Sphaerulina mu...
XP_007920136 305 PDAATRQDRVLEKPDAHFEQAMWIACWEMLRRGKsWEEVSQWCEERHESWRAIALGKg---------------------- 362  Pseudocercospo...
CCX06581     303 PDAPSRQQRKLEDEDEAWEAYLMRLVWGFLRKGE-MDNALELCEDAGEFWRAASLSGGADAWDAKIdgphe------ndd 375  Pyronema ompha...
EGX49966     300 PDGPIRQERNVAEGDNYYDTTFYKVLWGFIRKGD-FVGAAEWCRKCDQAWRAPVMLGGRDAVDWVIdeevaddemydasp 378  Arthrobotrys o...
EPS42823     296 PDGPLRQERNVALGDNYYDTTFYKALWGFIRKGD-FKNAAEWCRKCDQAWRAPVVLGGRDAVDYLIdeevaddemydasp 374  Dactylellina h...
CCJ29617     193 PDAPTRQRKLLDDKDFEFERKFLRNLFLLIRSGD-FDKACDICKETGNFLRSAILQGCIEYRDPLIe------------- 258  Pneumocystis j...
XP_002175266 208 PDADLREEKRLEERDDDFENNFMQHLFWLFRSGE-FEEMVELSKRSGNQWRAVSIQGMIEYRDSIVdsk----------l 276  Schizosaccharo...
Q10331       230 PDADIRDDKRLDERDDNFERQFFHTAFCLFRSGS-FEELLELCRRTGNHWRSASLQGILEYRDNLIddv----------l 298  Schizosaccharo...

5A9Q_4       395 lEPVEGNPYRRIWKISCWRMAEDELF---NRYERAIYAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSvat 471 
EME48757     333 -VQPTEALSTATWRSMCYLASKSTTA---NDYEAAVYGLLSGNVTMAQKAARTVDENLYVHYNAALIRQFDLYLEMHhtd 408  Dothistroma se...
XP_016765165 375 -SDGSDVASNSAWRKMCYLASQSGCT---SDFEAAVYGLLGGAVNAMQKVCHTLDDRLYANYSSYLVRQFDLYLVNNfpd 450  Sphaerulina mu...
XP_007920136 363 -FDQSQLRSSATFRKIAYAASKSKVS---NSYEAAVYGLLGGNIHATQKVCRSMDDHLHAHYSAALVRQFDKFLAVNhpn 438  Pseudocercospo...
CCX06581     376 gEIVKGNRRRELWKRMCYANASNKTK---NVYERAVYGTLCGDIASVLPVCDSWEDLLFVHVNALVEGYYSSKLKKLqri 452  Pyronema ompha...
EGX49966     379 eQGPSGNRRRQLWRRACYALARRSSKrpgELWERAAYGLLAGDIDSTIPACDNWHDHVYTQVNALIEAEYENFLRREgrv 458  Arthrobotrys o...
EPS42823     375 eQGPSGNRRRQLWRRACYALAKRVSRvpgDTWEKAAYGLLAGDIETSLPACENWHDHIYAQVNALIEAHYERYLHQNgri 454  Dactylellina h...
CCJ29617     259 -LGVMGTKRKQLWKKMCYELSKQTEL---DPYERALYGALCGDLQSVLEVCETWEDYLWAYCNSICEYQITMNLKQLgki 334  Pneumocystis j...
XP_002175266 277 dTGTFGNKRKELWRRTCLALSREKKA---STFERATYGALCGDLKSVLPVCKTWEDHLWAFYNCMTQHSVNLYLNSVmps 353  Schizosaccharo...
Q10331       299 qSETSGNKRKELLRRSCLALTKNKRI---DSYERALYGALCGDLNSVLDVCTTWEDAMWAYYNSMTQYNLDVYLSSKapq 375  Schizosaccharo...

5A9Q_4       472 lde----------teelpREYLGANwtlEKVFEELQAT-DKKRVLEENQEHYHIVQKFLILGDIDGLMDEFSKWLSKSRN 540 
EME48757     409 rlpr--------grlhgnRDLAQDPd--AQIVELIGALrKKPTTSREAVQPIKIIQSYLLANDVGSLIHTLGFTISYTAR 478  Dothistroma se...
XP_016765165 451 rapf--------arsgvtEEELQDPd--QAIYDLLARLrKEPETAKEAVQPMKIIQSYLIANDIGSLIHTLGFAVAYADR 520  Sphaerulina mu...
XP_007920136 439 rgr----------ndplpDGTLEDQd--LAIYDLLARLrSEASTKDESVQPMKIIESYVIANDVGSMIHTLGFALSLTDQ 506  Pseudocercospo...
CCX06581     453 pavvsnfplfdaisyharhdslndasimSRIIDEIAENnEIADSKL----PLRTIQGSLISMRFHDPVIELDRQLQLFET 528  Pyronema ompha...
EGX49966     459 saqvlklpap------daletlgtrnlvAKIVDSLSRPnDFRFAASPQNTALRAVQGAIISNRIPKLVNIFAFQLGEFRR 532  Arthrobotrys o...
EPS42823     455 snstlklhip------davatlgtrnvmAKIVDSLSRPdDHRFTASSQTTALRAVQGAIISDRIPKLVNIFAEQLREFRR 528  Dactylellina h...
CCJ29617     335 kpsqvvi------------ipnvdsislPSILENLIHS-DNELIRNDANEPMRIIQSNIITSKVDELILNLNTQLQDIKn 401  Pneumocystis j...
XP_002175266 354 pqtrlpp------------idsgagltpESIFQALAQS-DSSEVKDAAAQPLRHVQARIICNNVRQLFMEFHEQLEAVRs 420  Schizosaccharo...
Q10331       376 tetqlpp------------vdsglgltpELIFNSLSNS-SIASIQEEASHPLIKLQTHIICNKISEILSSAHIQLEAIRt 442  Schizosaccharo...

5A9Q_4       541 ------------------Nl----------PGHLLRFMTHLILFFRTLGL--QtkeEVSIE----VLKTYIQLLIREKHT 586 
EME48757     479 qtgkadhmi-ldlepfwqEdsnqpeaevalNPQTLRIATHMGIMIRQLAGgmArkeNQEREaeenVYVAYIQSLRAAGKR 557  Dothistroma se...
XP_016765165 521 qlhsmeqmivhlepfwddKrsnqpemevalDPQTLRIVVHMGIILDTLSP--QkldWEAQSakenTIVAYIQALRAAGKR 598  Sphaerulina mu...
XP_007920136 507 qsgrrekmiahlepfwenAsqnepeeaiglNPHTLRIAAHMGILLDILAP--QdlqGDEAIakmnVIVAYIQTLRAAGKR 584  Pseudocercospo...
CCX06581     529 vpd------------yepTadenaygldatEPRSLRVIVHILMILQTIGAg-FtegTEYHKaaenVIAGYIMTLGGYDKY 595  Pyronema ompha...
EGX49966     533 dpg-------------yePekdtntpvdctDWKLLRIVTHLIILLQHLGQ--WpesGPDADaaqeVVAGYIRMLAAAEKY 597  Arthrobotrys o...
EPS42823     529 dpg-------------yePdkdtntpvdctDWKLLRVITHIIIILQHLGQ--WpeeGQDADaaqeVIAGYIRMLAAAEKY 593  Dactylellina h...
CCJ29617     402 gtss---------------------iditsVPSFLRFVVHFILLLRHTNIs------IDQNncnsLIQAYIELLAAGGKQ 454  Pneumocystis j...
XP_002175266 421 gvke---------------------ldrttEPHVLRVLVHLIYAIRFAGFe------VDNYasdsILQAYIELLASAGKC 473  Schizosaccharo...
Q10331       443 gnape--------------------sgdlvTPPLLRILTHIILFLKISGLa------VDEYtsdsIIQAYIELLASAKKV 496  Schizosaccharo...

5A9Q_4       587 NLIAFYTCHLPQDLAVAQYALFLESV--T---EFEQRHHCLELAKEADLDVATITKTVVe-NIRKKDNgefshh------ 654 
EME48757     558 ELIPLYLSKLHASRYIVTMADILEDI--T---SPREQDVMLRLMRQYELDVILILRDHSqfLMNKYMSdelhpqtrrpak 632  Dothistroma se...
XP_016765165 599 DLIPVYASRLSKGAYVATMSRVLQDI--T---DEREQQETLGLLKQYGLDVVFILNEQLgyMLDQYLAndlgrmekplkm 673  Sphaerulina mu...
XP_007920136 585 DLIPVYASRLSMGAYVMVMSHVLEDI--T---TPREQDETLKLLRQYNLDVVFILNEQLgyVLDKLLTknlkaekpvnml 659  Pseudocercospo...
CCX06581     596 ELVPLYASRLTPLKAIQVMGKSLASFegS----KSRREDLIRSMHQYGIDVDGCLRQTMiqCLTMTEPkyvntlssa--- 668  Pyronema ompha...
EGX49966     598 GIIPLYASRLSRDRCVEVMGEVL-----MhvtEEATREDIIRSFRSYDLDTQATLKRTMenAFIQTEVfykheelpiqil 672  Arthrobotrys o...
EPS42823     594 KIIPLYAARLGHARCVEVMGEVL-----LhvvTENTRDDMMRSFASYGLDVKATLRRTMenAFVQTEPlykhdelpiqvl 668  Dactylellina h...
CCJ29617     455 DIVPLYVAQLPHDMSIEIYAKFLni------nDDQQRIDQLHLAAKYKLDILNSLRRTVdiVYSTALInddifnsf---- 524  Pneumocystis j...
XP_002175266 474 ELVPLYISNLSGHIRDETYARFL-----VlieDEKQRLEQLKLAKKFSFNIDAAVNTAVerIFEETSTnvfsqn------ 542  Schizosaccharo...
Q10331       497 NLVPLYIQYLSNQVQYEAYSRFL-----IlvdEESARSEQLQLAKKYSLDINHAALLAVeyVYDEVVSvspeevh----- 566  Schizosaccharo...

5A9Q_4       655 ---------------dlapalDtGTTEEDRLKIDVIDWLVF-DPAQRAEALKQGNAIMRKF---------------LASK 703 
EME48757     633 ilekaedtllypgqriilgffSdEPQEGDDAIVRSLRWFTL-VDGYWQETFAALSLALRKS---------------LVAG 696  Dothistroma se...
XP_016765165 674 lets--qeahhpsqriasdfvPeHSIEDDRAIVASLRWFNI-IDGQWEKTFGNLSLALRKA---------------LIAG 735  Sphaerulina mu...
XP_007920136 660 kps---ddakhpgqhiseeflAdEHPEEDSKVIASLKWFDI-VEGLWERTFYSLSLALRKA---------------LISG 720  Pseudocercospo...
CCX06581     669 -------------qgfvfngfQdEIASEDIRLIRGMEWLMLgSEELRGDLVRSGCEVYKRF---------------LLTG 720  Pyronema ompha...
EGX49966     673 ------------sefsipqqdrrKVQPEDEKLIRTAEWMLH-LDEMKEDLIHAGVMMFKRF---------------YLTG 724  Arthrobotrys o...
EPS42823     669 ------------sqfslswqerrKVQPEDEKLIRTAEWMLV-ADDMKEDLLHAGVMMFKRF---------------YLTG 720  Dactylellina h...
CCJ29617     525 --------------tlelvpiTsTPSEWDLHQIRALEWMKS-SDDLKYDIIYKSNILYRRFlcmntyrfekfwliiLVRG 589  Pneumocystis j...
XP_002175266 543 ---------------ielksiDaPVDIESQRLIRTLEWMLI--TCQFTKLIGYSNAAYRLF---------------LRDG 590  Schizosaccharo...
Q10331       567 --------------tvylksiEePVEPSYKKLICTLEWLLI--TSQTDELLRFANLVYRFF---------------LSIG 615  Schizosaccharo...

5A9Q_4       704 KHEAAKEVFVKI-PQDSIAEIYNQCEE-Q--GM---------ESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSV 770 
EME48757     697 RLACALQIIKEFpYDNVALRKNYKILGrSinPFdheg-eppcGRARWDFLRRTSRCYYELELVVRAIASLHEWRIREAEY 775  Dothistroma se...
XP_016765165 736 RLGCALYIVDEFpYETLARRKSYQVIGkSinPMdpdsdlsagEGSTTELLARQSRTYYELELVMTAIQALASWRAEEEAY 815  Sphaerulina mu...
XP_007920136 721 RIALAIKIINTYpYEDIAVRKSYQEIGkSynPMddeqapsaeAASHHIRMRKESRCYYELSLLVQAIKALGSWRTQEAEY 800  Pseudocercospo...
CCX06581     721 RLSAAKILFEQLnSRSIIPPKNTNGYDeTfeEE----------TDLVDETAVAGAMYMQMEGLIASMVELEKWQSAIKKP 790  Pyronema ompha...
EGX49966     725 RLDAARALAERI-PSSYIVSSEDEENDd-----------------LRDEYQGFASVYIEYEFLIEGLDALDEWSRLLAAG 786  Arthrobotrys o...
EPS42823     721 RLDAARTLVERI-PSKDLVPDDLEDNDd-----------------LSEEAKTIASVYIEYELLIEGLDALDSWSKLLAQG 782  Dactylellina h...
CCJ29617     590 KLNAAQTLNLRL-SSSVLITKDMVESEdSp---------------EQDKKFRHATEYLGYSSLCIGYMRYENWKNIMSNG 653  Pneumocystis j...
XP_002175266 591 NINAANLLDSRL-PSETLVTNDMISQTpDt--------------pENEAQLRVALEFMSYSSLCSAFFNYHEYSKLLNTL 655  Schizosaccharo...
Q10331       616 ELNSAYDLYTHI-PSDALNTLSSSDGEp-----------------ENDSKFRDAYELMNYRALCRALKFYQEWEELSKQE 677  Schizosaccharo...

5A9Q_4       771 PQK--PALIPQPtFTEkvahehkekkyemdfgiWKGHLDALTADVKEKMYNVLLfvdgGW---MVDVREdak-------- 837 
EME48757     776 TQN-------ALrMSS-----------------APPLLKTAKEEVDLAMNAVLTr---KL---LTHPVG----------- 814  Dothistroma se...
XP_016765165 816 TLK-------KPkLSG-----------------AGPTLKASKEAVDEAMLPVVEg---NL---LLNPVD----------- 854  Sphaerulina mu...
XP_007920136 801 IEK-------HPrLTG-----------------ASPDLKAAKEAVTEAMDPVLN----GL---LLLGDSfada------- 842  Pseudocercospo...
CCX06581     791 MRIdr---------------------------tlPRKLKPLYDSVSRSVPDIIK----NF---LDEPVFl---------- 826  Pyronema ompha...
EGX49966     787 TATkrEGGIAALrRGK-----------------FKDELQIAYENAESKLGVLVN----SW---LVQSQHhs--------- 833  Arthrobotrys o...
EPS42823     783 TAMkrEGGTAAVrRTK-----------------LKDELQAAYENAESKLGLLVN----SW---LVQCNHha--------- 829  Dactylellina h...
CCJ29617     654 LNDi-KNKIDSTeKRQ-----------------WKLDVQVSIN--LSVYILIFRe---QWknaLQPSTSlskeigctqah 710  Pneumocystis j...
XP_002175266 656 VHNqsAEEIKLSvLLK-----------------NNEDLKKLASDCISCFSELIRt---NW---LHPSTFsltke------ 706  Schizosaccharo...
Q10331       678 VFEdsAVTKASTsYKV-----------------WKKKLNFASRKCVKSFTDLLQa---NW---LHPSTLelkpd------ 728  Schizosaccharo...

5A9Q_4       838 -----------------------edHeRTHQMVLLRKLCLPMLCFLLHTILHSTg-------------------QYQECL 875 
EME48757     815 -------------------------HdEAMDLDIIRREYIPEVIIAYNTVLHSAgsii-------------trnNLVQSM 856  Dothistroma se...
XP_016765165 855 -------------------------EeEAADLELIRKWYFPELIIAYNAVHHAAgymi-------------sreHLVKSM 896  Sphaerulina mu...
XP_007920136 843 ----------------------dekAdEKADCAQIRQWYVPELVIAYNTVLHSAgyli-------------srdNLIDSM 887  Pseudocercospo...
CCX06581     827 ---------------------------SMPGVVEIRGIYIPEMVISLHRVHVEAgrli-------------nkvYYMNAL 866  Pyronema ompha...
EGX49966     834 -----------------------daE----QVKHIRNTYVPDITIALHNIHLAAglnl-------------nksYYSKCL 873  Arthrobotrys o...
EPS42823     830 -----------------------dsE----QVKHIRNTYVPDITMALHGVHLAAghnl-------------nksYYSKCL 869  Dactylellina h...
CCJ29617     711 slypslkvlyicflippynlkyttdPiIYNELVKIRNIYIPELVCLLHKVYYDThtlfprravfiflstltlhrNLHACM 790  Pneumocystis j...
XP_002175266 707 --------------------dngdvYd---QLIHIRNIFIPEIVISLHRIYENQe-------------------DFQSCL 744  Schizosaccharo...
Q10331       729 --------------------ddpllYk---TLMTIRNLYVPELILGLHNVYFSLe-------------------DYDSCF 766  Schizosaccharo...

5A9Q_4       876 QLADMVSSERHkLYLVFSKE-ELRKLLQKLRESS 908 
EME48757     857 DLSVAVANEQNgLTDCFLEArRMKELVTSFAQTS 890  Dothistroma septosporum NZE10
XP_016765165 897 DLSVTIANDDYhLSETFVAAgRMRELVDSFAHTS 930  Sphaerulina musiva SO2202
XP_007920136 888 DLSVTVADEKNlLSEVCVQAgRMRELVASFASTS 921  Pseudocercospora fijiensis CIRAD86
CCX06581     867 ELAADVADPERnTVDCFKGTgRLEEYVEEVAAAS 900  Pyronema omphalodes CBS 100304
EGX49966     874 DLAVLVAKPSSgVAETFIATgRMAKYVDELANVS 907  Arthrobotrys oligospora ATCC 24927
EPS42823     870 DLAVLVAKPSSgVADTFVATgRMAKYVDELANVS 903  Dactylellina haptotyla CBS 200.50
CCJ29617     791 ELSCIVADDEKkIYEAFLLThRMPQYLKLLRQAS 824  Pneumocystis jirovecii
XP_002175266 745 TLATQVAGDDKkLYDCFLASgRMKEYVRLLSKVS 778  Schizosaccharomyces japonicus yFS275
Q10331       767 ALANEVASEDLkLYHCLIKSgRLVEYVSYLGKAG 800  Schizosaccharomyces pombe 972h-
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