3VG8


Conserved Protein Domain Family
TTHB210-like
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cd11669: TTHB210-like 
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Hypothetical protein TTHB210, a sigma(E)-regulated gene product found in Thermus thermophilus, and similar proteins
TTHB210 is an uncharacterized protein found in Thermus thermophilus, and is controlled by the sigma(E) /anti-sigma(E) regulatory system. It is one of the five proteins of the extracytoplasmic function (ECF) sigma factor sigma(E)-regulated gene products whose physiological function have not been determined. Its crystallographic structure reveals a novel homodecamer although it is a dimer in solution.
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Statistics
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PSSM-Id: 212168
Aligned: 26 rows
Threshold Bit Score: 67.808
Created: 14-Mar-2012
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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oligomer
Conserved site includes 39 residues -Click on image for an interactive view with Cn3D
Feature 1:oligomer interface [polypeptide binding site]
Evidence:
  • Structure:3VG8: Thermus thermophilus Hypothetical protein TTHB210 interactions with neighboring molecules in a homodecamer; contacts at 4.0A
  • Comment:TTHB210 forms a novel homodecamer, but is a dimer in solution
  • Structure:3VG8: Thermus thermophilus Hypothetical protein TTHB210 dimer; contacts at 4.0A
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                     #      #  ###         ## #             ### #         ############  
3VG8_G         2 NVSEALKgaLPNFIp----gLGTLYVdpstlPEGPFLAYDra---gNLVKVVFXVPLkkln--eshKYVDIGTKTLRAlg 72  Thermus thermop...
YP_002892912  32 TLPADVVkiSPVVPa-----MGEHWAnpkdlPLGPIYGVSe----gRVIFLEFMIDRdt-----laKGTSFTDLKSKAgi 97  Tolumonas auens...
YP_863454     40 TSNLKAErsKPVEKvn--dfYGSAQPig-ngVARSYVSINhe---gEPVSIGVLFSEkalenlgneALNLTLELHSKArg 113 Gramella forset...
YP_004494223  64 EEMEPPEg-MFFGSev---eVGEGSAr---tFVLLDDDGApt---eVGIRLSEGALEalpd--apeGPPEFWEMELPDea 131 Mycobacterium s...
ZP_09308721   27 PAGAGGVsgLVEGPah---pVGAGNAr---tYVTVDEAGTpa---tIGVRLDAAALDdlpg--allPVTEAYVLELPEea 95  Rhodococcus pyr...
CCE96668      33 YQQISKLvkLPDFLp----gMGQLFVdpatlPAGPFLAYDhd---gKLVSTIYMLPTkd-----lnPDKSFDNLAAPGg- 99  Sinorhizobium f...
ZP_09669294   47 TAKKATSekLKTFYgpa-qhVGNGVAr---aFVEINRDGTpe---tIGVRISEKGLEklpg-adpaGHGPTYTLRIPNqt 118 Gillisia limnae...
YP_001768271  77 YRKVSSLvnLPGFLp----gIGALYVkpgtlPAGPFRAFDrh---dRLVSTIYMIPTed------fQNKKAFDLKGAAg- 142 Methylobacteriu...
XP_001743569   5 CRTVAALlcLATAAlak-ieMSELGGr---mDVKLYVDGN------KAIWIDMNASAfgal--qpgAPTDEWDETWAVpe 72  Monosiga brevic...
XP_002954843  11 QDYLQTYviLPVDHtsrtppLAVGVElt-egFVSKATKLPkllnipIPIGPTETFSYsa-----feQPAAFFPMVGTNp- 83  Volvox carteri ...

Feature 1             ########    ####           # # #             
3VG8_G        73 i--trIDHVNXIPSG-PHPGVs-------ePHYHIELVLVsvDQERKVLE 112 Thermus thermophilus HB8
YP_002892912  98 p-lpsVEHVDFDWEPdGHEGYt-------vPHYDIHLYFVphNEHMAIKP 139 Tolumonas auensis DSM 9187
YP_863454    114 ---liVNHIDFGYNPmGHPGPvf-----mqEHFDIHFYWIsvEEKLSIPF 155 Gramella forsetii KT0803
YP_004494223 132 e-dtvFQFVSLDWAShGHEPPglf----dvPHFDIHFYMIeaDEVMAIDP 176 Mycobacterium sp. DQS39A1
ZP_09308721   96 a-ataFDHVTVDWNShGHDPQhgf----dvPHFDVHFYLLdrPTVESIHP 140 Rhodococcus pyridinivorans AK37
CCE96668     100 ----nVDHVDVYYNA-GHPGVe-------ePHVHVVLWHVaaAGEASVAK 137 Sinorhizobium fredii HH103
ZP_09669294  119 a-glpFDHIDLNYNPqGHPAPgiy----tfEHFDFHFYMIsvAQKMQLTD 163 Gillisia limnaea DSM 15749
YP_001768271 143 ----kADHITIYFNA-GHPGVe-------vPHYHIVVWHVskKEEARVAR 180 Methylobacterium sp. 4-46
XP_001743569  73 nndvpYNHVFAAYNPaGHPGYdgfghgygtPHMDIHFFSIseEDRNSLAQ 122 Monosiga brevicollis MX1
XP_002954843  84 -----FGFVYWSYAFnGHPGVgiy----dvPHFDFHFMFPsyDYWWNQEW 124 Volvox carteri f. nagariensis

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