Conserved Protein Domain Family
cls

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PRK01642: cls 
cardiolipin synthetase; Reviewed
Links
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Statistics
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PSSM-Id: 234967
Aligned: 240 rows
Threshold Bit Score: 551.694
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
93006556   28 SWTDFAGLGLIFHIILMIV--MTLRIVSVQRNIGVAIAWIAVLFTLPVFGLIAYVLVGEPMIGRRyrqRMDQARLLMNEM 105
152974719  35 GIRNISFLGITSILFTISAflIGCVIFLENRHPSKTLTWLIVLGIFPVIGFFAYLLFGQNFRRKR---MFQKKALLDEQA 111
163939093  35 GIKDVSILGIISILFTVSAflIGCVIFLENRHPSKTLTWLIVLGIFPVFGFFAYLLFGQNFRRKR---MFQKKALLDEQA 111
172058056  26 SVYMVGWLSIVIILVVLS---VFVIILLENRNPERTLVWALVMMALPVVGVFVYFTFGQNYRRKK---MFRLKAMLDEES 99 
218902392  35 GIKDVSILGIISILFTVSAflIGCVIFLENRHPSKTLTWLIVLGIFPVFGFFAYLLFGQNFRRKR---MFQKKALLDEQA 111
229918461  23 YYWSSQVIGLFSILVFLTTfsILLVILLENRNPQRTLIWAIVMIGFPVIGLFAYFVFGQNYRRKR---MFKEKAMLDEET 99 
49184132   35 GIKDVSILGIISILFTVSAflIGCVIFLENRHPSKTLTWLIVLGIFPVFGFFAYLLFGQNFRRKR---MFQKKALLDEQA 111
49479132   35 GIKDVSILGIISILFTVSAflIGCVIFLENRHPSKTLTWLIVLGIFPVFGFFAYLLFGQNFRRKR---MFQKKALLDEQA 111
52144139   35 GIKDVSILGIISILFTVSAflIGCVIFLENRHPSKTLTWLIVLGIFPVFGFFAYLLFGQNFRRKR---MFQKKALLDEQA 111
118476770  35 GIKDVSILGIISILFTVSAflIGCVIFLENRHPSKTLTWLIVLGIFPVFGFFAYLLFGQNFRRKR---MFQKKALLDEQA 111
93006556  106 AQRERLv------FDEGQEVLPTHYrgvSHIGTRWTGFGVFSNHDMQLLTHANIIFKRLIDDINAAQRSILMEFYIIYPK 179
152974719 112 FLQYKGhed-yreRILQKHKHQELL---FRLADRLGALNISFQTETKVLTNGEETFQAILQGLQKAKHHIHMEYYIVRDD 187
163939093 112 FLQYKGhed-yeeRILRNHKHQELL---FRLADRLGALNISFQTETRTLTNGDETFQEILDGLNRAKHHIHMEYYIVRDD 187
172058056 100 YIKYRTqfdhgihnQVFQHGHYTKV---VKLIDSISRLPISYNSHTKVLTNGQEKFPLLLAEIRQAEHHIHLEYYIVRDD 176
218902392 112 FLQYKGhed-yeeRILRNHKHQELL---FRLADRLGALNISFQTETRTLTNGDETFQAILDGLKRAKHHIHMEYYIVRDD 187
229918461 100 YLAYRQkamtlspsLMFAHDDYEKL---MHLTSSLNQLPVSSNTYTQILTNGREKFSKLLPALKGASRHIHLEYYIFRED 176
49184132  112 FLQYKGhed-yeeRILRNHKHQELL---FRLADRLGALNISFQTETRTLTNGDETFQAILDGLKRAKHHIHMEYYIVRDD 187
49479132  112 FLQYKGhed-yeeRILRNHKHQELL---FRLADRLGALNISFQTETRTLTNGDETFQAILDGLKRAKHHIHMEYYIVRDD 187
52144139  112 FLQYKGhed-yeeRILRNHKHQELL---FRLADRLGALNISFQTETRTLTNGDETFQAILDGLKRAKHHIHMEYYIVRDD 187
118476770 112 FLQYKGhed-yeeRILRNHKHQELL---FRLADRLGALNISFQTETRTLTNGDETFQAILDGLKRAKHHIHMEYYIVRDD 187
93006556  180 GQVLDVIESLMAAAQRGVECHILIDSVGSFSFFNSkAHRKLEKAGVFVHQSlPVGLFKTLFKRSDLRNHRKIVVIDGYIG 259
152974719 188 KLGTKIKDILIQKVKEGVVVRFLYDAVGSFKLSNA-YIEELNKAGVEMIPF-FPVRFPILNDKINYRNHRKIVVIDGNEG 265
163939093 188 KLGTEIKDILIKKSKEGVVVRFLYDAVGSFKLSNS-YIEELNDAGVEMIPF-FPVRFPILNDKINYRNHRKIVIIDGNEG 265
172058056 177 ELALELQEALIERAKAGVEIRFLYDAVGCFSTDKS-YFKKMELAGIEVRPF-FPVVLPFISSKSNYRNHRKIVVIDGTVA 254
218902392 188 KLGTEIKDILIQKSKEGVVVRFLFDAVGSFKLSKS-YIEELNDAGVEMIPF-FPVRFPILNDKINYRNHRKIVIIDGNEG 265
229918461 177 RISREIQRILIEKAKAGVEVRFLYDAVGSIHTSGT-FFEEMKQAGVQVQAF-FPVVLPLVSSKTNYRNHRKIVVIDGTEA 254
49184132  188 KLGTEIKDILIQKSKEGVVVRFLYDAVGSFKLSKS-YIEELNDAGVEMIPF-FPVRFPILNDKINYRNHRKIVIIDGNEG 265
49479132  188 KLGTEIKDILIQKSKEGVVVRFLYDAVGSFKLSKS-YIEELNDAGVEMIPF-FPVRFPILNDKINYRNHRKIVIIDGNEG 265
52144139  188 KLGTEIKDILIQKSKEGVVVRFLYDAVGSFKLSKS-YIEELNDAGVEVIPF-FPVRFPILNDKINYRNHRKIVIIDGNEG 265
118476770 188 KLGTEIKDILIQKSKEGVVVRFLYDAVGSFKLSKS-YIEELNDAGVEMIPF-FPVRFPILNDKINYRNHRKIVIIDGNEG 265
93006556  260 YIGSFNLVDpKFFKQNKDVGEWIDVAIRSVSdndiSIATAMAKVVVTDIGAENSDnldalhqrvnsytrklyvrnptind 339
152974719 266 FVGGLNIGD-EYLGENKYFGFWRDTHLYLRG----EAVQSLQLIFLQDWFYMTGE------------------------- 315
163939093 266 FVGGLNIGD-EYLGKDKYFGFWRDTHLYLRG----EAVQSLQLIFLQDWFYMTGE------------------------- 315
172058056 255 FTGGINVGD-EYMGKDKMFGFWRDTHLLVRG----EAVSELQLIFLQDWYYMTGE------------------------- 304
218902392 266 FVGGLNIGD-EYLGKDKYFGFWRDTHLYLRG----EAVQSLQLIFLQDWFYMTGE------------------------- 315
229918461 255 FTGGLNVGD-EYLGEHSKFGFWRDTHLYVRG----EGVSELQLIFLQDWYYMTGE------------------------- 304
49184132  266 FVGGLNIGD-EYLGKDKYFGFWRDTHLYLRG----EAVQSLQLIFLQDWFYMTGE------------------------- 315
49479132  266 FVGGLNIGD-EYLGKDKYFGFWRDTHLYLRG----EAVQSLQLIFLQDWFYMTGE------------------------- 315
52144139  266 FVGGLNIGD-EYLGKDKYFGFWRDTHLYLRG----EAVQSLQLIFLQDWFYMTGE------------------------- 315
118476770 266 FVGGLNIGD-EYLGKDKYFGFWRDTHLYLRG----EAVQSLQLIFLQDWFYMTGE------------------------- 315
93006556  340 insrikvlddgienvetpctgamstvIPQMP--VVKGVV-------AQLIPSAPQVTAHVIYNTLVTVLHRANHCICITT 410
152974719 316 --------------------------AVLAPeyLQAQSVegdhwggVQLVAGGPDNKWETIKHLYFAMIASARKSIWIAT 369
163939093 316 --------------------------AVLAPeyLQAEAVegdhwggVQLVGGGPDNKWETIKHLYFAMIASARKSIWIAT 369
172058056 305 --------------------------RLFTPyyMKPLEVmeestggVQIIASGPDEPHETMKSLYFGLITEARSSVYIAS 358
218902392 316 --------------------------AVLAPeyLQAKAVegehwggVQLVAGGPDNKWETIKHLYFAMIASARKSIWIAT 369
229918461 305 --------------------------RLFTPfyLEPLETvrsasggVQIVASGPDEPYETMKSIYFSLINAAKKSVYISS 358
49184132  316 --------------------------AVLAPeyLQAKAVegehwggVQLVAGGPDNKWETIKHLYFAMIASARKSIWIAT 369
49479132  316 --------------------------AVLAPeyLQAKAVegehwggVQLVAGGPDNKWETIKHLYFAMIASARKSIWIAT 369
52144139  316 --------------------------AVLAPeyLQAKAVegehwggVQLVAGGPDNKWETIKHLYFAMIASARKSIWIAT 369
118476770 316 --------------------------AVLAPeyLQAKAVegehwggVQLVAGGPDNKWETIKHLYFAMIASARKSIWIAT 369
93006556  411 PYFVPDEALSGALVTAAKRGVKVTLIIPEKVDSFLVQHASQAYYQELLEAGVTIALFKGGLLHAKTVVIDDDYCIFGTVN 490
152974719 370 PYFIPDDDILSALKVAALAGIDVRLLMPSKPDKRTVFYASRSYFPELLDAGVKIYEYEKGFLHSKVVIVDSDLASIGTAN 449
163939093 370 PYFIPDDDILSALKVAALAGIDVRLLMPSKPDKRTVFYASRSYFPELLDAGVKIYEYEKGFLHSKVVIVDSDLASIGTAN 449
172058056 359 PYLIPDEDLMTALKTAAMSGIDVRILLPSFPDHKVVFYASRSYFDDLLLAGVKIYEYNKGFMHSKVIVVDDAIATIGTAN 438
218902392 370 PYFIPDDDILSALKVAALAGIDVRLLMPSKPDKRTVFYASRSYFPELLDAGVKIYEYEKGFLHSKVVIVDSDLASIGTAN 449
229918461 359 PYLIPDEDIMSALKTASLSGIDVRIVLPSYPDHKIVFYASRSYYEELLLAGVKIYLYEKGFMHSKVIVVDDGLATIGTAN 438
49184132  370 PYFIPDDDILSALKVAALAGIDVRLLMPSKPDKRTVFYASRSYFPELLDAGVKIYEYEKGFLHSKVVIVDSDLASIGTAN 449
49479132  370 PYFIPDDDILSALKVAALAGIDVRLLMPSKPDKRTVFYASRSYFPELLDAGVKIYEYEKGFLHSKVVIVDSDLASIGTAN 449
52144139  370 PYFIPDDDILSALKVAALAGIDVRLLMPSKPDKRTVFYASRSYFPELLDAGVKIYEYEKGFLHSKVVIVDSDLASIGTAN 449
118476770 370 PYFIPDDDILSALKVAALAGIDVRLLMPSKPDKRTVFYASRSYFPELLDAGVKIYEYEKGFLHSKVVIVDSDLASIGTAN 449
93006556  491 IDMRSFYLNMEVSLAIYTPEMVAQVAACQDSYLQSCRFLTLDQWQRRHKAERLFDNVIRLFSPLL 555
152974719 450 MDMRSFHLNFEVNAFLYDTGSIRKLVQDFEEDLQVSSEIHGDHFHKRRLHKRIVESTYRLLSPLL 514
163939093 450 MDMRSFHLNFEVNAFLYDTGSIRKLVQDFKDDLEESSEIHVDRFHKRRLHRRIVESTYRLLSPLL 514
172058056 439 MDLRSFHLNFEVNAFLYGTNSVHELTRDFYEDFSNSSQVERQVFIQRSFGQRLIESISRLFSPLL 503
218902392 450 MDMRSFHLNFEVNAFLYDTDSIRKLVQDFKDDLEESSEIHVDRFHKRRLHRRIVESTYRLLSPLL 514
229918461 439 MDFRSFHLNFEVNALLYNTNSVHQLKQDLYDDFEGSHELVLEEFAKRSFFIKLVESLARMFSPLL 503
49184132  450 MDMRSFHLNFEVNAFLYDTDSIRKLVQDFKDDLEESSEIHVDRFHKRRLHRRIVESTYRLLSPLL 514
49479132  450 MDMRSFHLNFEVNAFLYDTDSIRKLVQDFKDDLEESSEIHVDRFHKRRLHRRIVESTYRLLSPLL 514
52144139  450 MDMRSFHLNFEVNAFLYDTDSIRKLVQDFKDDLEESSEIHVDRFHKRRLHRRIVESTYRLLSPLL 514
118476770 450 MDMRSFHLNFEVNAFLYDTDSIRKLVQDFKDDLEESSEIHVDRFHKRRLHRRIVESTYRLLSPLL 514
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