Conserved Protein Domain Family
PRK05192

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PRK05192: PRK05192 (this model, PSSM-Id:235362 is obsolete)
tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG
Statistics
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PSSM-Id: 235362
Aligned: 929 rows
Threshold Bit Score: 417.522
Created: 9-Dec-2010
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
156742847   6 PFIYDLIVVGAGHAGCEAAHAAARMGCRTLLLTIDLDKLAHMSCNPSIGGPAKGHLVREIDALGGLMGRVTDRTFIQIRL 85 
29839891    5 PINYDVIVVGAGHAGCEAAFCSAKMGASVLILTSNLDTIAKLSCNPAVGGIGKGHIVREIDALGGIMAEVTDQSGIQFRI 84 
33241974    5 PIAYDVIVVGAGHAGCEAAYCSAKMGVSVLMLTSNLDTIAKLSCNPAVGGIGKGHIVREIDALGGIMAEVTDQSGIQFRI 84 
46447473    7 PVRYDVIVIGGGHAGCEAALASARMGLRTLLLTMNLDTIAKMSCNPAVGGIAKGHIVREIDALGGEMGKVIDVTGIQYRM 86 
182412705   1 -----MIVCGAGHAGIEASLAAARVGAFTLLLTGNLDTVGQMSCNPAIGGQAKGQIVREIDALGGEMAINTDVTGIQFRL 75 
187735314   9 FPLFDVLVVGAGHAGIEAALAASRLGCSVAVLTHNLDTIGQMSCNPAIGGLAKGHIVREIDAMGGAMGLNTDATAIQFRM 88 
294055630  10 NQPYDVIICGAGHAGCEAALAAARMGASTLMLTGNLDTIAQMSCNPAIGGQAKGHIVREIDALGGEMAVNTDTTAIQFRL 89 
297621984   5 PAVYDVIVMGGGHAGCEAALASARMGAKTLLLTMNLDTIGKMSCNPAVGGIGKGHMVREIDALGGEMGKVIDCTGIQYRM 84 
62184767    5 PINYDVIVVGAGHAGCEAAFCSAKMGASVLILSSNLDTIAKLSCNPAVGGIGKGHIVREIDALGGIMAEVTDQSGIQFRI 84 
89898690    5 PISYDVIVVGAGHAGCEAAFCSAKMGASVLILTSNLDTIAKLSCNPAVGGIGKGHIVREIDALGGIMAEITDRSGIQFRI 84 
156742847  86 LNESKGPAVQAPRAQADKRLYAKVMKETLETTPNLDLRQAMIERILLpqppgrNGSAapaddpagvqpgHY-AVITHTRR 164
29839891   85 LNQTKGPAVRAPRAQVDKQMYHIHMKRLLESTPGLHIMQGTVESLLD-------NEN------------VIqGVTTKEGI 145
33241974   85 LNQTKGPAVRAPRAQVDKQLYHIHMKRLLENTPGLHIMQATVESLLD------KEGV------------IS-GVTTKEGW 145
46447473   87 LNATKGPAVWAPRAQADKLAYQSEMKHRMERVSNLDIKQGTIEDLLI------ENDH------------IC-GVITKEGI 147
182412705  76 LNHTKGPAVQSPRAQCDKKAYQFRLKHTLELQPHLQLFQATVTGLIF------DGAK------------VI-GCRTNLDI 136
187735314  89 LNASKGPSVRAPRAQCDKTAYRTRMKMVLETAPGIRLFQGDVVKLLVngeqqaT------------------GAVTSLGC 150
294055630  90 LNATKGPAVQAPRAQCDKKAYQYRMKHVIELQPNLDLFQATVEGLIY------RSGR------------VV-GVRTNLDV 150
297621984  85 LNATKGPAVWAPRAQADKAAYQFEIKHRLEKQENLEIHQGTVEEIFV------ENDT------------VQ-GVATKEGI 145
62184767   85 LNQTKGPAVRAPRAQVDKQMYHIHMKRLLESSPGLHIMQGTVESLLD------NENV------------IQ-GVTTKEGI 145
89898690   85 LNQTKGPAVRAPRAQVDKQMYHIHMKRLLESTPGLHIMQGTVESLLD------KENV------------IQ-GVTTKEGI 145
156742847 165 VYQSRALVLTTGTFLRGRAITGEAIWGAGRAGEAPATALGEDLAALGFPLVRLKTGTPPRIDARTIDFSQTSVQQGS--- 241
29839891  146 TYLGKTVILSSGTFMRGLIHIGDLNFPGGRLGDPAATGLSAALKERGFPISRLKTGTPPRLLASSIDFSVAEEQPGD--- 222
33241974  146 MFSGKTVVLSSGTFMRGLIHIGDRNFSGGRLGDPSSQGLSEDLKKRGFPISRLKTGTPPRLLASSINFSCMEEQPGDlgv 225
46447473  148 SYDCQAIVLSSGTFLRGLLHIGETNYSGGRAGDQPSVGMSASLEKYGLKLGRLKTGTPPRINKRSIDFSCTEEQPGD--- 224
182412705 137 EFYGRTVVVTTGTFLRGLMHIGSNKNEGGRLGDFSARTLSGSLQEAGIELRRFKTGTPPRLLGRSLDFSKMEEQKGD--- 213
187735314 151 AIHARSVIICSGTFMKGLLHVGLQHITGGRMGCASSS-LSADLAMLGFQVERLKTGTSPRVNGRSIDFSVCEIQPGD--- 226
294055630 151 EFYGHTVVVTTGTFLRGLMHVGQNMNEGGRMGDFSAKGLSGSFLEAGIELERLKTGTPARILGSSINFEGLEEQEGD--- 227
297621984 146 YFTAPTVVISSGTFMRGLLHIGERNFSGGRAGDQPSVGLSGCLKKLGFHLDRLKTGTPPRINKRSINLSLTEEQPGE--- 222
62184767  146 TYLGKTVILSSGTFMRGLIHIGDLNFPGGRLGDPAATGLSLALKERGFPISRLKTGTPPRLLASSIDFSVTEEQPGD--- 222
89898690  146 AYLGKTVILSSGTFMRGLIHIGDRSFSGGRLGDPAATGLSAALKERGFPISRLKTGTPPRLLASSIDFSVTEEQPGD--- 222
156742847 242 ---PTPLFFGHYyrvlgeippepa--------ftgapacaypepLRAAWRPQLPCYLVHTTPEFHEIVRRNLDRAPLFSG 310
29839891  223 ------PGVGFVhr----------------------------dePFVPPLPQVSCYITHTTQKTKDIIAANISRSALYGG 268
33241974  226 gfvHRTEPFQPP-------------------------------------LPQLSCFITHTMEKTKAIISANLHRSALYGG 268
46447473  225 ----PGVKFSYDn-------------------------------EGIPRLPQVSCYITYTTEETKQIILSNIHRSPMYSG 269
182412705 214 ---ANPTFFAFHdtredggvfh-------------vehgkpqgeAIPPGCEQVSCWMTYTTARTAELVRENLSRSAMYGG 277
187735314 227 ---APEALFSYRsrdilkrdse-------------pfctlntwgDENFRMKQMPCWITYTNQTTHDIIRKNLKFSPLYSG 290
294055630 228 ---ALPTLFAFYdtrgvddvfhvehssdaeralfhvehsgqrklGWAPGTDQVSCYMTYTSAETQSVVHENLHRSAMYSG 304
297621984 223 ----EGIRFSFDd-------------------------------EGKRKLPQVSCYITYTTQETKQIILDNIHRSPLYSG 267
62184767  223 ------PGVGFVhr----------------------------sePFVPPLPQVSCYITHTTEKTKDIIAANIHRSALYGG 268
89898690  223 ------PGVGFVhr----------------------------dePFVPPLPQVSCYITHTTEKTKEIITANIRRSALYGG 268
156742847 311 IIEGVGPRYCPSIEDKIVRFADKERHGLFLEPEGWSTHEVYVQGCNTSLPEDVQWAMLRSIPALRRVELMRAGYAIEYDA 390
29839891  269 RIEGIGPRYCPSIEDKIVKFADKERHHIFIEPEGIYTQEVYVNGLSTSMPFDVQYNMIRSVHGLENAIITRPAYAIEYDY 348
33241974  269 CIEGVGPRYCPSIEDKIVKFSDKERHHVFLEPEGLHTQEIYANGLSTSMPFDVQYDMIRSVLGLENAIITRPAYAIEYDY 348
46447473  270 KIKGVGPRYCPSIEDKVVRFSDKERHQIFLEPEGLQTQEVYVNGVSSSLPFDVQLAFIKSIPALRHAEIMRPAYAIEYDY 349
182412705 278 EIEGVGPRYCPSIEDKFVRFADKPRHLLFLEPEGRGTDEFYVNGLSTSLPFDVQLELVHSIPGLGEAVLLRPAYAVEYDY 357
187735314 291 IIEGVGPRYCPSIEDKIVRFAEKNSHQVFLEPEGRSTEEFYLNGVSTSLPYSAQCDFIHTIPGLENAQLIRPGYAVEYDF 370
294055630 305 EIEGTGPRYCPSIEDKFVRFKDKDRHMLFLEPEGRNTNEWYINGLSTSLPFDVQLAMLRSVQGLEKVHMLRPAYAVEYDF 384
297621984 268 KIQGVGPRYCPSIEDKVVRFSDKERHQLFLEPEGLQTEEIYVNGISSSLPLDVQYAFIKSIPALRNAEITRPAYAIEYDY 347
62184767  269 RIEGIGPRYCPSIEDKIVKFADKERHHIFIEPEGIHTQEVYVNGLSTSMPFDVQYDMIRSVLGLENAIITRPAYAIEYDY 348
89898690  269 RIEGIGPRYCPSIEDKIVKFADKERHHIFIEPEGIYTQEVYVNGLSTSMPFDVQYEMIRSVRGLENAIITRPAYAIEYDY 348
156742847 391 LATGEIAADMSSRRIPGLFFAGQINGTTGYEEAAAQGLMAGINAARFIqgkPPIILRRDEAYIGVLIDDLITKEIREPYR 470
29839891  349 VHGNVIYPTLESKIVEGLFLCGQINGTTGYEEAAAQGLIAGINAVNKVlkkPAFIPSRQESYIGVMLDDLTTQVLDEPYR 428
33241974  349 IHGNVIHPTLESKLIEGLFLCGQINGTTGYEEAAAQGLIAGINAVNKVfnrPPFIPSRQESYIGVMLDDLTTQILDEPYR 428
46447473  350 VISGQIDFSLECKKIGGLFLAGQINGTSGYEEAAGQGLMAGINAANKVmgkAPLILKRSEAYIGVMIDDLVTKGLDEPYR 429
182412705 358 APPTQLKMSLESQRVEGLFLAGQINGTSGYEEAAGQGLIAGVNAARKGrgeQPLVLGRHEAYIGVLIDDLVTKGTEEPYR 437
187735314 371 CPPTQLHPTLETKLVENLYFAGQINGTSGYEEAAAQGLMAGANAALKTlgkPSLVLRRDQAYIGVMIDDLVTKGTDEPYR 450
294055630 385 APPTQLYPSLESKQVENLFFAGQINGTSGYEEAAGQGLVAGVNAVQKLrglEPMVLKRHECYLGVLIDDLVTKGTKEPYR 464
297621984 348 VTSGQIKPSLESKKVEGLFLAGQINGTTGYEEAAAQGLLAGINAASKVagrEPLILKRSESYIGVMIDDLITKGLDEPYR 427
62184767  349 VHGNVIYPTLESKLIEGLFLCGQINGTTGYEEAAAQGLIAGINAVNKVlkkPAFIPSRQESYIGVMLDDLTTQILDEPYR 428
89898690  349 VHGNVIYPTLESKTIEGLFLCGQINGTTGYEEAAAQGLIAGINAVNKVlrkPDFIPSRQESYIGVMLDDLTTQVLDEPYR 428
156742847 471 MFTSRAEHRLLLRTDNADLRLTRLAGELGLVDRERVEAVERKREESERLLRVLRGQRLF-----PsaatnARlsdvgiap 545
29839891  429 MFTGRAEHRLLLRQDNACLRLSHYGRDLGLLSQERYEIFENQKQIIEDEKARLNKTFKKygnsvV--------------- 493
33241974  429 MFTGRAEHRLLLRQDNACARLSHYGYELGLLSEERYELVKKQNQLLEEEKVRLQKTFRQygqsvV--------------- 493
46447473  430 MFTSRAEHRLLLRQDNADLRLRRYGYEVGLVDQTRYDRVKEKQRIMEEESERLAKTFKQ-----V--------------- 489
182412705 438 MFTSRAEHRLLLNHGSAELRLLHHASGCKLLNVNRLDNIARKKEAIESWVRRLESERTS-----------EG-------- 498
187735314 451 MFTSRAEFRLLLRQDNADLRLAPLAFEAGLITCEMARKAEDRKNAVEEGIIKAAALKHEg-------------------- 510
294055630 465 MFSSRAEHRLLFNHPSAELRLKHHSSAMGLVDPERMQRIEAKDRAIRSWVDRLESERVG-----------GQ-------- 525
297621984 428 MFTSRAEHRLLLRQDNADLRLRKYGYAYGLIDQKRWETLCLKAETIEWEMTRFEKTFKQ-----V--------------- 487
62184767  429 MFTGRAEHRLLLRQDNACLRLSHYGRDLGLLSKERYEIFENQKQIIEEEKLRLSKTFKKygnsvV--------------- 493
89898690  429 MFTGRAEHRLLLRQDNACLRLSHYGRDLGLLSKERYELFEHQKQIIEEEKLRLSKTFKKygnsvV--------------- 493
156742847 546 LSSemSAEDVLRRP----EVRYEQLRQA---LDLPACDADIAEQVEIEAKYGGYLQKQQREVERLRRMEARRIPPDFDFT 618
29839891  494 -----SLAKALCRP----EVSYDILret-fpDDVRDLGSTLNASLEMEIKYAGYIDRQKSLIHSLSKSENMVIPEDIDYQ 563
33241974  494 -----SLAKALSRP----EVSYDMLrea-fpNDIRDLGAVLNASLEMEIKYSGYIDRQKILIQSLEKAESLLIPEDLDYK 563
46447473  490 SNKgyTLTQLLCRP----ENTYASLLKEy-pDVMQNFGEEINFQIELNLKYAGYIDRQTSEVAKLAHVEKIQIPIGFDFS 564
182412705 499 -----TLAEIIRRQnaraELPSELMRQS----------KPVRDEVLYRVLYSGYWEREQRHIDKLAQIEAVRIPAAIDYL 563
187735314 511 ----vSLSTWLKRP----GNDWTLLp----eELKKMFHVEHLDAIATDIQYEGHIERQKKQAEKIIRMENKTIPSDIDYK 578
294055630 526 -----LYGDIVRRT--------RSVSDFp--DDLKALPREVKDEVMYRVAFRGYLEREAKQIEKMRHIDKILIPTDFDFR 590
297621984 488 NGKgfSLAQLLRRP----EMTYESLLETy-pEAVVDHGEEINFQIELNLKYSGYISRQNTEIERISQVENLRVPEHFDFN 562
62184767  494 -----SLAKALCRP----EVSYDTLREAfpeDIRD-YGSTLNASLEMEIKYAGYIDRQKALIHSLSKSENMVIPEDIDYQ 563
89898690  494 -----SLAKALCRP----EVSYDTLREVf-pEEVRDFGSILNASLEMEIKYAGYIERQKSLIHSLSKSENMTIPEDIDYQ 563
156742847 619 ALRGLRNEARQTLQRFRPATVGQAARLAGINPADVAILIVALERRGRRDMA 669
29839891  564 SISSLSLEAREKLAKFTPRTIGSASRISGIACADIQVLMVAVKKHAHQ--- 611
33241974  564 QITALSLEAQEKLAKFTPRTLGSASRISGIASADIQVLMIALKKHAHH--- 611
46447473  565 TVNGLRNEAKQKLNQIAPRHLGQALRISGVSPADISILMIALTRYQEPIEK 615
182412705 564 RIPGLRRESALKLAAQRPDTLGQASRISGVNPADVSILMVLIKTGKTPSLP 614
187735314 579 HVHALKKEAVIKLGNIRPATIGQASRIPGITPADIALLLVHLQKRSRQQT- 628
294055630 591 KVRGLRNESAEKLAAISPRTLGQAGRISGVNPADISILMVYLDSQAKA--- 638
297621984 563 QVSGLRNEAKQKLCRHNPLTLGQASRISGVSPADISVLIVELTKRERQTIA 613
62184767  564 SISSLSLEAREKLAKFTPRTIGSASRISGIACADIQVLMVAVKKHAHQ--- 611
89898690  564 SISSLSLEAREKLAKFTPRTIGSASRISGIANADIQVLMVAVKKHAHK--- 611
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