6SCJ,1ZT3


Conserved Protein Domain Family
Thyroglobulin_1

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pfam00086: Thyroglobulin_1 
Thyroglobulin type-1 repeat
Thyroglobulin type 1 repeats are thought to be involved in the control of proteolytic degradation. The domain usually contains six conserved cysteines. These form three disulphide bridges. Cysteines 1 pairs with 2, 3 with 4 and 5 with 6.
Statistics
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PSSM-Id: 459665
Aligned: 165 rows
Threshold Bit Score: 51.1496
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6SCJ_A         96 CQLQKQQILLSG---------YINST---DTSYLPQCQ-DSGDYAPVQCDVq----qVQCWCVDAE-GMEVyGT-RQLGR 156  human
EFN66575      339 RDRMLAEILS-----------VSERQ---GRGYVPQCR-EDGGFETRQCSRn----gLVCWCVDDE-GRKIsGS-MGPSK 397 
XP_015206106   86 CRLMHLEMLNKRrtg---tilPGGRL---DIEYDPECD-GSGMFKPKQCDDd----sNLCWCVDSA-GVRVtDK-TGDD- 151 
XP_002195947   27 CLLMKAEVMGSKsgrrekpkdAFEDT---DGLYDPECE-NNGTFKAKQCNG------STCWCVNTA-GVRRtDK-HDTD- 93  
XP_004752925   74 CLVMKAEMTSSKsgrrvrpegAFQNN---DGLYDPDCD-EKGLFKAKQCNGt-----tTCWCVNTA-GVRRtDKdNEEE- 142 
XP_002810812   73 CLLLKARMSAPKnart-lvrpSEHALvdnDGLYDPDCD-PEGRFKARQCNQt-----SVCWCVNSV-GVRRtDK-GDLS- 142 
XP_005571019   63 CRRHLDSVLQQLqt------eVYRGA---QTLYVPNCD-HRGFYRKRQCRSsqgqrrGPCWCVDRM-GKPLpGS-PDGNG 130 
XP_003772687  169 CRRHLDTVLQQLqa------eVYRGA---WTLYVPNCD-HKGFYRKRQCRSsqglrrGPCWCVTRM-GQNLtSP-TESD- 235 
XP_029286559  118 CRKLLTTLIQGLda------hLFKSH---HDIYMPNCD-KRGFFRKKQCWSsrgkrrGKCWCVDQK-GMPVsSN-TKQKG 185  Cottoperca gobio
XP_001843227  248 QARMLSELLS-----------VNERE---GRGYVPQCDgPGGSFSTRQCSRn----gLVCWCVDPKnGNKIkGT-MGAAQ 308  southern hous...
6SCJ_A        157 PKRC 160  human
EFN66575      398 KIDC 401 
XP_015206106  152 -PKC 154 
XP_002195947   94 -LKC 96  
XP_004752925  143 -ISC 145 
XP_002810812  143 -LRC 145 
XP_005571019  131 SSSC 134 
XP_003772687  236 -ANS 238 
XP_029286559  186 GLSC 189  Cottoperca gobio
XP_001843227  309 MVNC 312  southern house mosquito
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