3R4C,1YMQ


Conserved Protein Domain Family
Cof

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COG0561: Cof 
Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases [Coenzyme transport and metabolism, General function prediction only]
Statistics
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PSSM-Id: 440327
Aligned: 819 rows
Threshold Bit Score: 48.2079
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3R4C_A        11 M-I-----K--------VLLLDVDGTLL---SFEt-H--KVSQSSIDALKKVHD---S-GI-KIVIATGRAASDLHEI-D 64 
NP_110115      1 -mT-----KtskasglsWFFCDLDGTLLryqNNQ--H--LIEPTTKRAVAQLVE---S-GA-NFVVATGRKPSDVRNIyK 65 
WP_081581643  20 K-I-----S--------LVVADIDGCLT---QGK--Ks-SIDIDSLKLLRDYNNglvKmGLpPLVFCTGRPQPYVEALsQ 79 
WP_055409608   8 AlVellpqRi------cGLAVDIDGTIT---ERRqrGdfRLSLEAVEALRALED---A-GI-RVMLVTGNSVMVTAGVaR 73 
WP_023025510   1 -mK-----Kii-------aFSDCDGTLL---FDD--Y--KFSDYTINTVKNIYE---N-GS-YLIPVTARTLKNLKNIaK 55 
BAA79744       7 S-V-----R--------VAALDIDGTLT---ERR--GaaRLDGCSIAVARLLND---L-GV-TSILMTGNSLPVARGVaV 62 
WP_011009426   2 A-C-----K--------VLVVDLDGTLT---LGR--NtyELSAEALLALRRARD---A-GI-RVVLATANGLDFALTVaR 57 
WP_013925328   1 M-P-----G--------LIALDIDGTVT---DFG--G--VIPPEVVAYLSELVS---D-GW-NVVFITGRTFTDGFKIlQ 54 
WP_013181725   1 M-N-----T--------LIALDIDGTLT---SDL--H--SIPQEIESYLGLLAG---K-EV-MIALVTGRCFSLAYPLlK 54 
WP_013943441   2 M-K-----G--------TIALDIDGTIT---AKD--H--MIPDRVAAYFETLHR---D-GW-KFILVTGRIFSFAMMTlT 55 
3R4C_A        65 AVPy-D--G-VIALNGAeCVLr-dGSviRKVAIP---A----Qd-fRKSMEL----A-R-Ef-D-FAVALelnegvfvnr 123
NP_110115     66 ELGieQasPyLIANNGAvVWDlkrNSylNKQTLSlsdF----Dl-iDHI-NQtlnqLnH-Ey-G-CI--Lyglndqvyfy 134
WP_081581643  80 LLGv-K--MpCVCENGAvIYKpdqDTilIHPTIR---P----Sf-lHEINR-----M-R-Ekfsdghlsgitfqvepgke 141
WP_055409608  74 YIGv-K--GpHVSENGClVYRr--GSf-TS--AC---RgtarAa-aRVLEEE----M-S----GiIEpswqnrcrfhdya 132
WP_023025510  56 QLKidElgGiIAGNNGAqIFDfktGKyiLNKTVd---K----Ni-iNEVFDLyyteAdE-Ek-E-CK--Vnfaseeivys 122
BAA79744      63 YLGl-E--GpVVAENGCvAVVg--GEr-VH--IC---SgrppEglvKRIME-----L------G-FKpswqneyryheys 119
WP_011009426  58 YLGi----RdVIAENGClVHLd--GVt-YE--LC---SgdmaEv-dRLVLST-----------GvVKpshqnkcrkydla 113
WP_013925328  55 PLSf-P--YyFAVQNGAiTLRmpqQEvvAKHTLG---T----Dv-fPAMENI----C-KdEpsD---FVIfagfehqdcc 115
WP_013181725  55 SWTf-P--YlLAIHNGAiILRmpeKKiiFKQYID---P----Kv-vETLDEI----V-SgEetD---FALytgienedic 115
WP_013943441  56 KLNf-P--FlLGVQNGAdLLImpeRKriRKNYLK---L----Dv-lKLLDEL----Y-AtEqgD---FIVyagydkgdfc 116
3R4C_A       124 ltptveqiagivehpvppvvdi--------------eemferkeccqlcfyfdeeaeqkvmpllsglsATR----WhpLF 185
NP_110115    135 hihapdsqafkqyfafyegefvqnqyl----eidglkteynlvkaiwffkevhqqkaviaqhftnqerLVI----TsaHS 206
WP_081581643 142 vcislnpisk-----------------------------dggeefslrekvvelynvvkdmvdqsifsVNH----St-TA 187
WP_055409608 133 ftvrrgs-----------------------------------------veeviqeaekllrerghqvkLSH----Sg-YA 166
WP_023025510 123 fgesentkkwaeimeqqfkvisksnei-----vedivsisiitkkgtdldtylhhfnkikskygndyrIDN----YhnRV 193
BAA79744     120 lipvka--------------------------------------------apgiverasaiaeeegyrAIW----Sg-YA 150
WP_011009426 114 yipl-----------------------------------------------redaverlrdvlgpgyvVES----Sg-YA 141
WP_013925328 116 yyrshcfskelleylkarsdafnsiwydvesfdnltlanfpslkcfgqvesasrisyrieneiglhapLIKdpfqNgyYV 195
WP_013181725 116 yfrpkqfsprlrsyvrkraelckenwvavdhfdslqlnsltaikcfgskesaqrikgkiekqlslhvpVIKdpvdQsvYI 195
WP_013943441 117 yyrptkhspkmltylekltrfcaepwqpvetfdlhqqstfplvkcfgtqaaceaieeklksiqgiqtsVIKdpidPslYL 196
3R4C_A       186 ADVNVAGTSKATGLSLFADYYRVKVS-EIMACGDGGNDIPMLKAAGIGVAMGNASEKVQsvadFVTD-TVDNSGLYKALK 263
NP_110115    207 FELVPLNVSKGHAINLIKQQVKITDN-QIMVLGDSYNDLPMFQHGVVKVTNHLAPDNLKqlatRVYElPA-SLFVGQALN 284
WP_081581643 188 VDITPFGIDKGVGVRWLSQLTSIDEQ-FMLGIGDSAGDIPFLTRVGYPAAPENACDAVKsvakYVSP-LPFAEGVVDIIN 265
WP_055409608 167 IHVRPLEASKGLGLSLALRYAGLNPD-CVIAIGDSVIDLEMREAGVLLAAVGNADPLLRkradIVVP-GESGKSVALLAK 244
WP_023025510 194 ISIAPKDIDKGYAVEIINKYLNNTGQyETYGFGDSYNDFPLIAAVDYGIAMKNALDELKetayDITEyPNYQDGVARYIN 273
BAA79744     151 LHIQPPGGGKARGVGEVLARIGAGWS-EVLAIGDGENDVEVLARAGYSGAPGDAAEQAKraakIVAR-SPGARGTLEIIQ 228
WP_011009426 142 IHVRPAGVDKGTAVKWLCQRLGVPCF-QVASVGDSDVDVGMLS-VSWGFAVGNATPAAKkaakVVVD-GPSGIGFKEAVE 218
WP_013925328 196 VQATHASVNKGSALRDLKQRLRVQ-T-PVIAAGDDNNDISMLEEADIRIIMVTAPDHLLqtatIIAP-PAREKGIIQGLQ 272
WP_013181725 196 AQATHPNIDKGTALGSILNGEKYL----IIAAGDDHNDLPMLKKADVKIVMDSAPSELKqmadIVAK-PAQELGIIEALE 270
WP_013943441 197 VLVTHANANKGSAVKDFMEKFSLP-R-PLITGGDDNNDIPLLRVGDMRIAMDGAPDALQnladIIAP-PAEKGGIVEALQ 273
3R4C_A       264 H-F 265
NP_110115    285 D-Y 286
WP_081581643 266 V-L 267
WP_055409608 245 I-I 246
WP_023025510 274 DkI 276
BAA79744     229 R-V 230
WP_011009426 219 I-I 220
WP_013925328 273 K-A 274
WP_013181725 271 N-A 272
WP_013943441 274 E-A 275
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