Conserved Protein Domain Family
TPR

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COG0790: TPR (this model, PSSM-Id:223861 is obsolete and has been replaced by 440553)
TPR repeat [Signal transduction mechanisms]
Statistics
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PSSM-Id: 223861
Aligned: 92 rows
Threshold Bit Score: 56.9763
Created: 7-Oct-2002
Updated: 23-Jan-2015
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1351653  454 PLPSVSSPIMRADSTPISHNlavtpsfspipQQSNKSIGNHKntsvanvsSKVANSKFERNISMMSNSNASSPAIFEVGA 533  fission yeast
16126716  66 PQVAQGVSGQFNQQQQEIRAlrqggfrgdffAQLELARRYEGqravdknlEDPVEAAVWYAMALANSGGYAPIAAYERRG 145  Caulobacter cresce...
15805511  23 PGQAAKYPLTTRITPAEAQAfarvldvglgkVEVQRLPGWRTklaarakaGDPLAQFMYARTYDLFTTGQGTPQDARVAM 102  Deinococcus radiod...
19074022  70 ARNIVLGVMSMESGSTNERAklaadllwsvaARVSRKYLRNShaflagepFRKLEKNFLSKRGVSNIVTMVYSGDDVSAR 149  Encephalitozoon cu...
15600279     --------------------------------------------------------------------------------      Pseudomonas aerugi...
15600280   4 GLWAVLCLAGVPVMANSKPF-----------VCANEKDHLPP--------LDPQADAWYREAAALAKPDTLRPWGRIVEI 64   Pseudomonas aerugi...
15600281   8 FLLIFLLSGNPVMAAELRPF-----------ICVNEKDHLPS--------LDPQADAWYREAVALAKPDTLRPWDRIVDL 68   Pseudomonas aerugi...
19113617   1 --------------------------------YETGAFDVESdiqrawdlYSSSANLGYTRSLYRLGVLLEDQGNLEEAV 48   fission yeast
19112891  68 SSWSLSSSDSIMSYDSLSDDvsvlsfldcplTTFETAPSIASfsnsaadvSSHSRSSSSWSAKLSRFTKHASKPSLSSNS 147  fission yeast
15642596   1 ------------------------------------------------------MKLRTVAASLLLAWHSSYNPAYAADL 26   Vibrio cholerae
1351653  534 EAKEKTKDaipchpddklmi---pspkivthgdamQEEQrlrqksqitpDDEVELAKVYLNALETLENkpslapdqa--- 607  fission yeast
16126716 146 KESRAVSR---------------------------FDDCraferrsaygALDRLLSRMSTEEREKVRNrvi--------- 189  Caulobacter cresce...
15805511 103 QWYTKAADqkfasaelflfnvyeysllgqpknprlAARYlqrayqhsggSVRAEAALELARQTNPEREdfrlpgfqpsak 182  Deinococcus radiod...
19074022 150 LFLSLLDNrkiy--------------------igdYIDVieflvksgyaRAFGYLGEIYYHGIGVKRS------------ 197  Encephalitozoon cu...
15600279   1 -------------------------------------------------MHNLANLYRTGWPGGVEKD------------ 19   Pseudomonas aerugi...
15600280  65 YSKAVERG---------------------------HWKA----------MHNLANLYRTGWPGGVEKD------------ 95   Pseudomonas aerugi...
15600281  69 YSKAVERG---------------------------HWKA----------MHNLASLYRTGWPGGVEKD------------ 99   Pseudomonas aerugi...
19113617  49 EYFEKGVS---------------------------ENDSac------cwRLSLLILEGMLDGVGEYAHr----------- 84   fission yeast
19112891 148 SDSSFSKSgsesna----------------lssrgSFELephgihrhvsRAKRLLSKFYSKFHHKKEDss---------- 201  fission yeast
15642596  27 GEPVPIYSe----------------------------------------AELIKLIEENKHLERVKADn----------- 55   Vibrio cholerae
1351653  608 ------syntrinvyRTRAVELLKkna--ypSKTQNTVPEALFL------------IGQFHSQGVl-------------- 653  fission yeast
16126716 190 ------------yilSTQSADGFRt-----lARMHDGYFGPFGEpsdnl--qaieaYGKPSQPGAp-------------- 236  Caulobacter cresce...
15805511 183 qtrayleeilklepkDTTALDWLMgiyldshDYSRALEMARRTDnsam-----wvqMALVLADDHpgfpaqpklaatflk 257  Deinococcus radiod...
19074022 198 ---------------LDQAMYFFSrgkemqdTMGACGVGKILMSdeyrdyknaksaLALANRLGQs-------------- 248  Encephalitozoon cu...
15600279  20 ---------------TQKALDLYQ-------KMIDLDVPQGFYD------------MGAMIGNRA--------------- 50   Pseudomonas aerugi...
15600280  96 ---------------PQKALDLYQ-------KMIDLDVPQGFYD------------MGAMIGNRA--------------- 126  Pseudomonas aerugi...
15600281 100 ---------------TQKALDLYQ-------KMIDLKVPQGFYD------------MAAMIGNRA--------------- 130  Pseudomonas aerugi...
19113617  85 ---------------HASGLELLErs----aDTADADVPSGLYS------------HALVNLHEHpglv----------- 122  fission yeast
19112891 202 --------------fDPLAPLVFApntsrvlRVTNEANASAISLeka-------tsLSSQEQPGSe-------------- 246  fission yeast
15642596  56 ---------------CQIVEDIVA-------RATRISLPSYEFL------------YGDMLAWG---------------- 85   Vibrio cholerae
1351653  654 ----------G-FRR---DL-----------GKAFELYSLAAKKGHPLSnyrvavclqtgtgvkpd-------------t 695  fission yeast
16126716 237 ----------AaLDLfrrND-----------VDAYLYNYLAVQTGDVSAyvmlkdfersspqrasygsfvetkakrwipp 295  Caulobacter cresce...
15805511 258 rrlaavkndkGeAEStlyLLmqlecekkisrADYQNVFDPAVYQRYLTWrvgcrv------------------------- 312  Deinococcus radiod...
19074022 249 ----------GeAEYlmyLLmvrr---peymHRSSSHMESALMYGYLPAicrdglnyymnreyin--------------- 300  Encephalitozoon cu...
15600279  51 ----------G-VKN---PA-----------TDGLTFLDKAASLGNPP-------------------------------- 73   Pseudomonas aerugi...
15600280 127 ----------G-VKN---PA-----------TDGLTFLDKAASLGNPP-------------------------------- 149  Pseudomonas aerugi...
15600281 131 ----------G-VKN---PA-----------TDGLTFLDKAASLGNPP-------------------------------- 153  Pseudomonas aerugi...
19113617 123 -------dlgSeNIRvpiDE-----------ATALKSFAKAAFLGHSSA------------------------------- 153  fission yeast
19112891 247 ----------IkKELslyDHe---------fDQILDLAIKAKKDGNLENaie---------------------------- 279  fission yeast
15642596  86 ----------VcVDQ---DV-----------ELGLYYMENAAHQGLPAA------------------------------- 110  Vibrio cholerae
1351653  696 skcvaiykkaaemdvVEAMFRIALIYLNGLlgQKrnisLGVQWLEra-ckSKGPESVRAMYELAkiyeqpdrygvsatp- 773  fission yeast
16126716 296 yefyppespdsgvphSDEADLSGEARESALyrIAelpfVHVGESLay-lrVIPTAVLDEKMLSVtevqtlqsmigrpntg 374  Caulobacter cresce...
15805511     --------------------------------------------------------------------------------      Deinococcus radiod...
19074022 301 acirfhpimdysdivYDLRKRAEANFVSGRyrQCamalLMCAELGsvssiRNAVYVLQRHSVLErqeeilfsl------- 373  Encephalitozoon cu...
15600279  74 ---------------ALTELGKFYIYVAKK--KD----LGLAYTH-----CAASQGYAPASYELg--------------- 112  Pseudomonas aerugi...
15600280 150 ---------------ALTELGKLYIYVAKE--KE----LGLAYAS-----CASSQGYAPASYELg--------------- 188  Pseudomonas aerugi...
15600281 154 ---------------ALTELGRLYIYVAGQ--DE----LGLKYTN-----CAAGQGYAPANYELa--------------- 192  Pseudomonas aerugi...
19113617 154 ------------------QLRMGAVYEFGKygCPvvprYSLFYYS-----AAAKRGETEADLAVakwylngsdg------ 204  fission yeast
19112891 280 ------------fleYIMPEVASQQNFVPYelAElykqRGTSQDL-----KSILPLYMLAASLG---------------- 326  fission yeast
15642596 111 ------------------LEQLGRYYSRG---------TLVQQDK-----ERAIPYLREAAAMG---------------- 142  Vibrio cholerae
1351653  774 ----erkfelykqsavygYAAAQCKLG---ECYEHGl-LGCLAEPRRSIFWYTRAAEQDYg--EAELGLSGwYLTGSEgi 843  fission yeast
16126716 375 rlapiekvravqyaavngSSKAQLVLA---VMYSEG--VGVPRDYARAYHWYEEAERQGS---AEAKYAMStFFSLGLqg 446  Caulobacter cresce...
15805511     --------------------------------------------------------------------------------      Deinococcus radiod...
19074022 374 ----------ymkllrkgDQDVVNRIG---DAYFYG--VGVGRSHSDAFAFYISAALMGD---PEGCYNVS-YMYEHG-- 432  Encephalitozoon cu...
15600279 113 --------------------AYYKIVE---HNFPKA--LV----------YYQVSVSQGGk--SAAFFLSR-VFGSET-- 152  Pseudomonas aerugi...
15600280 189 --------------------SYYELVE---NNYPKA--LS----------YYQVSVSQGGr--SAAFFLSR-VFGKRT-- 228  Pseudomonas aerugi...
15600281 193 --------------------MYYRLVA---HNYPKA--AG----------YYLLAASQGNd--DAAFFMSG-VFDKTS-- 232  Pseudomonas aerugi...
19113617 205 --------ipvdedlafmHAERASMAGnanAQFLMGylFDTRGNTEQATYWYNEAAKAGHseaIERLALLEnQIQEPEp- 275  fission yeast
19112891 327 ------------------HDRSSFLVG---EAFFYGt-YGARENKLRALQYYHLANDKGN---ADAMLALCkLYLRGLp- 380  fission yeast
15642596 143 ------------------NLNARIQLA---ELLLRD--YGSPLDYEDAYRWLYNSVTAD------QRTHNRiALLRQG-- 191  Vibrio cholerae
1351653  844 lpkngeea-llwahkaacKGLAKAQyavg---fmmEQGIGVAADPSSAHNWYIRAAKQGFPKAKKRLEeqALSSKQTHSK 919  fission yeast
16126716 447 vadqdrakavvyqidgalAGFKPSAwr------lqQLLAQVSRPPRAAGERPQPRPIYGADDYRAAPRadDRDPRQDQPG 520  Caulobacter cresce...
15805511     --------------------------------------------------------------------------------      Deinococcus radiod...
19074022 433 ------------------YGVKKSLmla-----fkYVLKIKPTDDMYLLLLYTYIRLLFKPIICFLLNkySVSICIGALV 489  Encephalitozoon cu...
15600279 153 ------------------PPASAMW----------YAPDEKLREAYYSIYKKLEADPDLRFPNLIEDY--PLPPHPTQGY 202  Pseudomonas aerugi...
15600280 229 ------------------PPSSAMW----------YTPDEKLEKFYYSLYLQIDADPDLRFPNLVKYN--PLPPHPVQGY 278  Pseudomonas aerugi...
15600281 233 ------------------PDVDRMW----------YAPDEKLHKLYDGIYDQLAADPDLRFPNLIKDH--PLPPHPTQGY 282  Pseudomonas aerugi...
19113617 276 ------------------ENITSSQypnqd-vikeIPVTASETSPPHAPAVSSTPVTSAPPVSQTKVTkvSVPKKTSKKF 336  fission yeast
19112891 381 -----------------gHIFPSSRrafeyahraaMLGHAPACYVLGKFYETGVGCVKDLAKSEAGFRagLINDSPITDA 443  fission yeast
15642596 192 ------------------------------------------------LERRMPENIIARAKRRETFW------------ 211  Vibrio cholerae
1351653  920 APKKKQ 925  fission yeast
16126716 521 SDRGGR 526  Caulobacter crescentus CB15
15805511     ------      Deinococcus radiodurans
19074022 490 VRRMYT 495  Encephalitozoon cuniculi
15600279 203 DADRPD 208  Pseudomonas aeruginosa PA01
15600280 279 DAARPD 284  Pseudomonas aeruginosa PA01
15600281 283 DADRPD 288  Pseudomonas aeruginosa PA01
19113617 337 LIKHNK 342  fission yeast
19112891 444 DALQIA 449  fission yeast
15642596     ------      Vibrio cholerae
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