1HXD


Conserved Protein Domain Family
BirA2

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COG0340: BirA2 (this model, PSSM-Id:223417 is obsolete and has been replaced by 440109)
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Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme transport and metabolism]
linked to 3D-structure
Statistics
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PSSM-Id: 223417
Aligned: 58 rows
Threshold Bit Score: 116.644
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1HXD_A    84 LPVIDSTNQYLLDRI--GELKSGD--ACIAEYQQAGRGRRGRKWFSPFGANLYLSMFWRLEQG--PAAAIGLSLVIGIVM 157 Escherichia coli
15618775   8 IEEIPSTNTMAKSYM--HLWDPYAltVISTKCQTAGTGKFGKSWKSSKGDLLNTFCFFITDLHi-DV---SRLFRLGTEA 81  Chlamydophila pneum...
15605458   8 IARTESTNTTAKEGL--SLWDPYAltVITTREQTAGRGKFGRVWHSTDQDLLASFCFFLSVNNv-DS---ALLFRIGTEA 81  Chlamydia trachomatis
15791487  12 VESIDSTHLFLCKQI--RNGKIDEnfAIYALEQINGVGSRENSWQSSKGNLHLSFCIKEEDLPk-DLPLASVSIYFAYLL 88  Campylobacter jejuni
15645754   9 FDSLPSTQTYLLEKL--KSNELKApiLIVAKNQSAGIGSRGNIWEGAKSALTFSLALNASDLPk-DLPMQANALYLG-FL 84  Helicobacter pylori...
19113070 359 APVIRSTQTLLDKNYrfLDSTNTGf-TVLGNYQTAGRGRGQNMWVSPYGTLAFSFIINVDAKNfsTTPIALFQYLMALAV 437 fission yeast
15642997   9 FESIDSTNRFLKENY---RFYPDGt-VVVALEQTSGYGRSGRHWHSPKG-GLWFSVLFKPRKP---LELSFYTRVFSVAV 80  Thermotoga maritima
17232748  30 FSTVASTNKTLWGLI--DQGAVTGs-VVIATQQTTGRGQWGRQWVSPTG-GLYVSVALTPKVD--ANASYQITLATAWGI 103 Nostoc sp. PCC 7120
15612133   9 FDSLPSTQTYLLEKL--KSNKLKApvLVLAKNQSAGIGSRGNIWEIVESALTFSLALNASDLPk-DLPMQASALYLG-FL 84  Helicobacter pylori...
16329423  41 PACTDSTNQILWDLR--HQGYHPPl-VAIAREQTAGRGQWGRTWQSPPG-GLYLSLWLATDLP--ISYGPHLVLWSAWGI 114 Synechocystis sp. P...
1HXD_A   158 AEVLRKlg----adKVRVKWPNDLYLQ------------DRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEE-S-VV 219 Escherichia coli
15618775  82 VVALCKdlg---itEAKIKWPNDVLVH------------GEKLCGVLPETLPVEGL-LGVVLGIGLNGNTTKQAL-K-DV 143 Chlamydophila pneum...
15605458  82 VMRLGEslg---iqEAVMKWPNDVLVQ------------GKKLSGVLCETIPVKTG-TCVIIGIGVNGNVGADEL-L-GI 143 Chlamydia trachomatis
15791487  89 KEVLQEkg-----sKIWLKWPNDLYLD------------DKKAGGVISAKISN-----FIIGGMGLNLKFAPQN--T-AL 143 Campylobacter jejuni
15645754  85 FKEVLKel----gsQTWLKWPNDLYLE------------DQKIGGVLVNVYKDMR-----VCGIGVNRVSKKWAC-L-DI 141 Helicobacter pylori...
19113070 438 VRGIREyapgyeniPAFIKWPNDVYVRvdkgginfqgkqYMKLSGIIVTSNYRKN-VLHLVVGCGINVSNLGPTVsLnTL 516 fission yeast
15642997  81 VKTLENmk-----iHANIKWPNDVYIN------------GRKLAGVLSEGIFEGAKPLAVVVGVGMNVNNEIPA----EL 139 Thermotoga maritima
17232748 104 ACQLREsg-----vNVGIKWPNDLVLE------------GRKLGGILTETKVSQGQISQAVVGVGINWANAVPETgI-NL 165 Nostoc sp. PCC 7120
15612133  85 FKEVLKel----gsQTWLKWPNDLYLG------------DQKIGGVMVNVYKGMR-----VCGIGVNRVSTKWAC-L-DI 141 Helicobacter pylori...
16329423 115 AHALIQhg-----iPVQVKWPNDLLLK------------GKKLAGIKTESKINGNRITAAIIGVGINWTNPVPATgI-AL 176 Synechocystis sp. P...
1HXD_A   220 NQGWITLQEAG--INLDRNTLAAMLIRELRAALELFEQEGLAP--YLSRWEKLDNFINRPVKLIIGDKEIFG-ISRGIDK 294 Escherichia coli
15618775 144 GQPATSLQEI----LGHPIDLETTR-ELLIHHLLGVLQEN----------------LPDSLATKSNRGNI---------- 192 Chlamydophila pneum...
15605458 144 DQPATSLQEL----IGRPVDMEEQL-KRLTKEIKHLIQT-----------------LP--LWGRE--------------- 184 Chlamydia trachomatis
15791487 144 CDIEISLKDLVs-EFLQKVEKKILWKNIFSKYMLEFEKSRKFS----VHHEGKVFSLENSFLYEDGSILLGDkRVYSLR- 217 Campylobacter jejuni
15645754 142 GASDGLIIEG----FLKKIEENLFWGEVLSKYALEFHRSNSFS--FHNDWGE-AMSLKDAELLEDGRICIKGkIYDRM-- 212 Helicobacter pylori...
19113070 517 VDEWNKNSDNPrlEKFSFEKLLASVLNQFDRYHRLLLEEGFSL--ILPEYYQYWLHSNQTVNLASGGKAIIQgITSDFGF 594 fission yeast
15642997 140 KTRAISLKEIMg-KEISIVKLMESMLKNARVIFRKYSRKKEALtrIWKRYLLQKEGDLISLEGKKGKIVKINpDSLLIDF 218 Thermotoga maritima
17232748 166 ESWQADQTHKP---ISCLETLTSKVLLGIESGMACLFQEGISI--LLSRYSELLVNMGDRVHVNDLSGIVVGvTPQGDLR 240 Nostoc sp. PCC 7120
15612133 142 GASDDWIIES----FLKKIEENLFWGEVLSKYALEFHRSNSFN--FHNDWGE-AVSLKDAELLEDGRICIKGkIYDRM-- 212 Helicobacter pylori...
16329423 177 GPFCEAESIQS---INSLTDLAEITLAGLTLGWHRYQREGIAG--ILVDYLQLFAHRGREISLTQGVG-----IIESVTA 246 Synechocystis sp. P...
1HXD_A   295 QGALLLEQD-----GIIKPWMGGEISLRSA 319 Escherichia coli
15618775     ------------------------------     Chlamydophila pneumoniae CWL029
15605458     ------------------------------     Chlamydia trachomatis
15791487     ------------------------------     Campylobacter jejuni
15645754     ------------------------------     Helicobacter pylori 26695
19113070 595 LLAQLLNENnepttKVVHLQPDGNSFDLMR 624 fission yeast
15642997 219 DGEIKKVYS-------LSPH---------- 231 Thermotoga maritima
17232748 241 VSLETDCVTdikapELYLEPGTISLGYRRS 270 Nostoc sp. PCC 7120
15612133     ------------------------------     Helicobacter pylori J99
16329423 247 QGELVVLIG-----QRREIILPGTVSLDYD 271 Synechocystis sp. PCC 6803
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