Conserved Protein Domain Family
CurA

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COG2130: CurA (this model, PSSM-Id:225041 is obsolete and has been replaced by 441733)
NADPH-dependent curcumin reductase CurA [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only]
Statistics
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PSSM-Id: 225041
Aligned: 16 rows
Threshold Bit Score: 406.296
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
15789969  42 DDCMRDTS-REWVFAERPEGEPDMDS---FELRERDVPEP---RHGELLVRVRYLSVDPYMRGRMRDSD--SYADPWTVG 112 Halobacterium sp. N...
16077812   1 ---MTASQ-QQIQLARRPQGIPVHED---FRFETIPVPEP---KQGEVLVKTLYVSVDPYMRGRMQDTK--SYVEPFALD 68  Bacillus subtilis
16126259   1 ---MTTS--REIRLKARPVGMPKDSD---FELATVELPAP---GDGEIQVKNLWMSVDPYMRGRMYDRP--SYVPPFQLG 67  Caulobacter crescen...
15596845   1 ---MTSQInRQYQLAQRPSGLPGRDT---FSFVETPLGEP---AEGQILVKNEYLSLDPAMRGWMNDAR--SYIPPVGIG 69  Pseudomonas aerugin...
17546485   1 ----MSNTyQRIVLASRPEGAVTPDN---FRLETAQIPEL---QDGQVLVRNHFLSLDPYMRGRMNDSK--SYAQPQPLG 68  Ralstonia solanacearum
15927767   1 ---MQN---KQILFNKIPEGMPQEDT---FKIEEIDTPKL---ESDGVLVQTLYISVDPYMRGRMTKAD--SYVQPFEIG 66  Staphylococcus aure...
19114906   1 --MVSNNAvIIKKYLDSTAGYPVIGEhlaFEKREFDLENAqvdEETPVLLKNIYTSVDPYLRMRMQSPKhaSYIPPLELG 78  fission yeast
2497058    1 MVLAKQWVlKNLPTPGEPFNFHFHDPactFELIEKELSSEq-lKDGELLLETTYLSNDPAQKFWISSMDk-NYAKGVQPG 78  baker's yeast
17228683  19 NFPMADAVnQQIVLKSRPFGEPQESD---FALVESPIPQP---GEGEVLSRTIYLSLDPYMRGRLSANA--SYAASTELN 90  Nostoc sp. PCC 7120
13475704   1 ---MSTETnIRIVLAARPQGRPKPSD---FRIESVGIAEP---GEGELLLQILYLSLDPYMRGRMNATK--SYAKPVEID 69  Mesorhizobium loti
15789969 113 EPLSGGVVGEVVESESDAYEAGDLVSGNGTWADYSLLDAA--------NVAPVD-PSVADLPAYLGVLGMPGRTAYFGLL 183 Halobacterium sp. N...
16077812  69 KALSGGVIAEVVS-DGNHLKKGDIVIGNLSWQEFSAVSES--------ALRKID-TSLAPASAYLGILGMTGLTAYFGLL 138 Bacillus subtilis
16126259  68 EALQGGAIGEVIASNDPDFKPGDIVSSMFGWREAYNAHPKslaaagmgAITKIE-THGIPPQAFLGVAGMPGMTAYAGLL 146 Caulobacter crescen...
15596845  70 EVMRALGVGKVLVSKHPGFQAGDYVNGALGVQDYFIGEPK--------GFYKVD-PSRAPLPRYLSALGMTGMTAYFALL 140 Pseudomonas aerugin...
17546485  69 EVMIGGTVGVVEASRNPAYAVGDNVVGMFGWQEVGISDGR--------GMQKVD-TRHVPLSAYLGSVGMPGVTAWYGLN 139 Ralstonia solanacearum
15927767  67 KPIVSHVVAKVIDSTLADYKKGDVVVGMLPWRIINHVQAD--------QITKVP-TTDVPLDLYLSVLGMPGQTAYHGLL 137 Staphylococcus aure...
19114906  79 KPFYNSTVAKVVKSTLDQYKPGMDVVFVSGWEEYTFVSKQal-----gFLQPINnPYKLPLIDFVGSLGMPSQTAYCGLK 153 fission yeast
2497058   79 EIIPARGIGKVLASRNKAFSPGDYVSAVTGWTTHAIISQEnv-----qGLRKLDkNKVGKLWWYLSVLGGTSLTAYFIFF 153 baker's yeast
17228683  91 SVIVGGTVSQVIKSHHLEFQAGDFVLSNHGWQTYAVAKGE--------TLRKLD-PNQAPLSYNLGVLGMPGLTAYAALL 161 Nostoc sp. PCC 7120
13475704  70 GVMEGGTVARVVKSRHAGFAEGDIVLSHSGWQGFALSDGV--------GLRKLD-PAAAPVTTALGVLGMPGFTAYAGLL 140 Mesorhizobium loti
15789969 184 EVGAPKP-----GDTVVVSGAAGAVGSVVGQIAK--HNGCRVVGFAGSEEKVDWLTEDLGFDAGINYKQVd---DYSAAL 253 Halobacterium sp. N...
16077812 139 DIGRPKE-----GETVVVSGAAGAVGSTVGQIAK--IKGARVVGIAGSDEKIDYLKQELQFDEAINYKTAd---DIQKAL 208 Bacillus subtilis
16126259 147 RVAALKD-----GDVVFVSAAAGAVGSIVCQIAK--LKGHTVIGSAGGPEKVAFLKS-IGVDHVIDYKATp---DVVAEL 215 Caulobacter crescen...
15596845 141 DVGQPKN-----GETVVISGAAGAVGSVAGQIAR--LKGCRVVGIAGGAEKCRFLVEELGFDGAIDYKNe----DLAAGL 209 Pseudomonas aerugin...
17546485 140 RIMHPKP-----GQTVAVSAASGAVGSVVGQLAK--LKGCRAVGFAGGKDKCDYVVNELGFDACIDYKAAkdpkELYAML 212 Ralstonia solanacearum
15927767 138 DIGQPKA-----GDTVVVSAASGAVGSVVGQIAK--IKGCRVVGIAGGDKKVNYLTETLGFDAGIDYKKe----DFAEAL 206 Staphylococcus aure...
19114906 154 HIGKPKA-----GETIYISAASGAVGQMAGQLAK--AMGLHVVGSVGSDEKFKICLD-SGYDSVFNYKKE----SPFKAL 221 fission yeast
2497058  154 TYAQLQEreedyGKVYLISGAAGAVGTVCIQLALnvFKASKVIAIAGGPEKVAFVESFGDNVVGVDYKDP----SFKQKL 229 baker's yeast
17228683 162 DIGQPKA-----GETVVISAASGAVGAVAGQIAK--IKGARVVGIVGSDEKRDYIVNELGFDVGINRRTQ----EVSSAL 230 Nostoc sp. PCC 7120
13475704 141 TIGQPKA-----GETVVVAAASGAVGSAVGQIAR--IKGARAVGIAGGADKCAFVRRELGFDAVVDHRAD----NFAEQL 209 Mesorhizobium loti
15789969 254 DDAAP--DGVDVYFDNVGGPISDAVFTKLNVDARVAVCGQIAHYNNE--DVPTGPRKLPQLIAP----RAKVQGLLV-GD 324 Halobacterium sp. N...
16077812 209 QNACP--DGVDVYFDNVGGPISDAVMNLLNEFARIPVCGAISSYNAEseADDMGPRVQSKLIKT----KSLMQGFIV-SD 281 Bacillus subtilis
16126259 216 AKVAP--KGIDVYFENVGGVHLEAAINSARPFARFALCGMISQYNET--SKPEGPSNIILAVGk----SLRLEGFIVsNH 287 Caulobacter crescen...
15596845 210 KRECP--KGIDVFFDNVGGEILDTVLTRIAFKARIVLCGAISQYNNK--EAVRGPANYLSLLVN----RARMEGMVV-MD 280 Pseudomonas aerugin...
17546485 213 KEATP--DGIDAYFENVGGDILDAVLRRMNPFGRIAMCGMIAGYDGQ--PLPLQNPQLILVS------RLTVEGFIVsEH 282 Ralstonia solanacearum
15927767 207 AQAVP--DGIDVYFENVGGTVGDEVFKHLNRFARVPVCGAISSYNHP--EADIGPRIQGTLIKK----QVMMRGFLV-SE 277 Staphylococcus aure...
19114906 222 PRLCP--KGIDIYFENVGGETMDAVLENMNLQGRIIFCGAISQYNNP---NPYRVKNLGMVLVK----SLTIQGFIVaNI 292 fission yeast
2497058  230 IEAAGgeNTVDYFIDNVGSNVLEAGVLLLKQRAMLIACGAISAYNDP---SKFVFKGYSFILTK----RLVVKGVLVtDN 302 baker's yeast
17228683 231 KEAAP--DGIDVYFDNTAGEILEAVLQQINLGARIPLVGLISQYNAS--SPPPGPNLLPLLIk-----RALIKGFLV-SD 300 Nostoc sp. PCC 7120
13475704 210 KAACP--DGIDVYFENVGGPVWDAVFPLLNEFARVPVCGLIAQYNTV--AAS-ADDRLPTLMQQvlhrSLTIRGFIQrEF 284 Mesorhizobium loti
15789969 325 FATRFGEASEQLGQWVAAGDIEHRE--TVVSG----LENAPDAFLGLFSGDNIGKQVVGVSE 380 Halobacterium sp. NRC-1
16077812 282 YSDRFSEGAKQLAEWLKAGKLHYEE--TITEG----FENIPDAFLGLFKGENKGKQLIKVSD 337 Bacillus subtilis
16126259 288 FDLYP-QFAKDMAEWIKAGKITWKE--TVEDG----VDRAPNAFLKLFTGENLGKMLVKLG- 341 Caulobacter crescentus CB15
15596845 281 YAQRFPEGLKEMATWLAEGKLQSRE--DIVEG----LETFPETLLKLFSGENFGKLVLKV-- 334 Pseudomonas aeruginosa PA01
17546485 283 MDVWP-EALRELGGSVAQGKLKFRE--SVAQG----LASAPEAFIGLLKGKNFGKQLVKLV- 336 Ralstonia solanacearum
15927767 278 FANAFKEASEQLATWVQEGKIQSQV--TIEDG----FENAPHAFKNLFTGDNFGKQVIKVTE 333 Staphylococcus aureus subsp. aureus N315
19114906 293 LPQYQEQYFEEMPKLIAEGKIKYKC--DVYDG----LESAPEAFIGMLQGKNSGKTIVKIAD 348 fission yeast
2497058  303 IDDFP-KALDKLGSLVKHGKIDLLKsaTLEDGtgdkFKNVPLIWKGLFSGVNKGKLITKVNN 363 baker's yeast
17228683 301 YQYRFPDFVRDVAGWLQSGQLKYKE--DVVVG----LENAPRAFIGLLRGDNFGKLIVKVSQ 356 Nostoc sp. PCC 7120
13475704 285 VDQRP-AFYRDMAGWIASGQVRYRE--DIVDG----LENAPQAFMGLLEGKNFGKLIVRVAQ 339 Mesorhizobium loti
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