Conserved Protein Domain Family
PRK09064

?
PRK09064: PRK09064 (this model, PSSM-Id:236370 is obsolete)
5-aminolevulinate synthase; Validated
Statistics
?
PSSM-Id: 236370
Aligned: 143 rows
Threshold Bit Score: 564.867
Created: 9-Dec-2010
Updated: 2-Oct-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
217977351   1 MEYRRFFDDAISKLKGERRYRVFADLARDAEAFPRAVWR--RGegGPEVNVTVWCSNDYLCMGRHPKVIAAMQDAAQAHG 78 
163855632   1 -MYQTLLSKKLSDLKASGQYRTFVTLNRICGQYPLAQLEg-----GDERPVIVWCSNDYLGMSQHLVVRQAMHDAIDRYG 74 
34496258   14 RELRVLFEDRLTQLKSEGLYRSFMPCEHDASHPGTTRYR--------QRQVEVWCSNDYLGLSQDPQVIERLRESAALHG 85 
82751601    1 ----------------------------------M------------------FCSNDYLGMSQNQEVINVMGDALKEYG 28 
182439088  16 ADTYAGLRAGLDKLRADGLYRDFVACSYLAEDRGHALHQ--------GRRIQVWCTNDYLGMSQHPDVMRAQIASTLRHG 87 
271970401   9 PHVFETIENKLRELKSNGLYRHYLPTAHMAASPGQTLRL--------GEEVQVWCSNDYLGLSQHPDLIRAQIESTALHG 80 
254797163   2 SNYSGVFAQALDTIKNEKRYREFVNLARISGEFPC------AIneETNEKIVIWCSNDYLGMGQNFTVCDSMKETIDRMG 75 
88608338    2 SNYSSVFARALDTIKNEKRYREFVNLARISGEFPCAINEetNE------KIVIWCSNDYLGMGQNFTVCDSMKETIDRMG 75 
254780604   1 MDFEKFFKDQINYLHHEKRYRFFTELAYEQYQFPYAIHNs----dEGSRKVTIWCSNDYLGMGKHPKVIENAQRTFEKCG 76 
294083651   1 MNYRDAFKSKLNQLVAENRYRHFVELERIVGAHPQAVWNa----pDGKRDVTVWCSNDYIGMGHHPDVIAALQDAAGQHG 76 
217977351  79 VGAGGTRNISGNNHPIVELEAELADLHGKEAGLVFTSGWISNLAAISTIGDILPDCLILSDQLNHNSMIEGVRRSRAERK 158
163855632  75 AGSGGSRNIGGSHGIFSQLERSLADWHSKEAALVFPTGFSSNDATLQCLLREIPDCVVISDEKNHASIINGIRATSTERQ 154
34496258   86 SGTGGSRNIAGTSISHVELERQLAQWHGKEQALVFNGGYTANFEFLSTLIAAVPDMAIFSDSLNHRSLIEGIRRHPCQKF 165
82751601   29 AGAGGSRNIGGSHKYFKLLENEIAKWHKKDSALVFPTGYSSNDASLQGLLRIFPEMIVFSDSKNHASIINALRSVKNKIE 108
182439088  88 TGNGGSRNIAGTSEAHVELETLLAGWHAKERALVFNSGYVANVETLTTLLRAEPRTMVFSDALNHRSLIEGVRTSGNDKY 167
271970401  81 TSMGGSRNIGGTSTTHVALESELAGWHGKERALIFSSGYVANFETLSVLLSAVPDMVVLSDENNHRSLIEGIRRARCEKR 160
254797163  76 AGAGGTRNISGNNKEVVLLEKTIARLHQKEAALSFVCGYVANLASISTIISLMKDCIAFSDQCNHSSIIEGIRSSRCEKR 155
88608338   76 AGAGGTRNISGNNKEVVLLEKTIAKLHQKEAALSFVCGYVANLASISTIISLMENCIAFSDQYNHSSIIEGIRTSRCEKR 155
254780604  77 IGAGGTRNIAGTNYYHVMLEKELATLHGKKAALIFNSGYIANWATIGTLCSQIDNIICFSDSHNHASIIEGINKARCKKV 156
294083651  77 TGAGGTRNISGTSASIVALEQELASLHNKERALVLTSGYVANEASISALAGLLNDCIVFSDAMNHASIISGIRHARVEKA 156
217977351 159 IFRHNDLAHLEQLLAEAGeSRAKLIVFESLYSMNGDIAPINAIADLAQRYNAMTYMDEVHAVGLYGARGGGIAERDGAMA 238
163855632 155 VFRHNDLDHLEESLARYPlERPKIVVFESVYSMDGDISPMAEIVDIAKQYNALTYLDEVHAVGMYGPRGAGLAAQLGIAD 234
34496258  166 IFPHNDVETLEKQLASVPlSQPKLIVFESIYSMDGDIAPIQVILDLADRYQAWTFLDETHAIGLYGGSGAGLCEEIE-ET 244
82751601  109 IFEHNNVKHLNELLNQYDiNTPKLIVFESVYSMDGDIAPIVEIVELAKEYNSLTFLDEVHAIGMYGEEGRGYSDVVGVQE 188
182439088 168 VFAHNDLTDLELALAAQPlDRPKLIVFESVYSMDGDVAPIREICDLAERYHAQTYLDETHAIGVLGPTGAGVCEEIG-ES 246
271970401 161 IFPHNDLVGLERCLAEYDeSRPKMIVFESVYSMDADASPISAICDLAQKYNALTYLDETHAIGVKGPTGAGICEEIG-ET 239
254797163 156 IFRHNDVNHLEELLSQVPrEAHKIIIFESVYSMDGDVAPIKEICDLAEKYNALTYIDEVHAVGMYGRHGGGITEEMDLVD 235
88608338  156 IFRHNDVNHLEKLLSQVPkGAYKIIIFESVYSMDGDVAPIKKICDLAEKYNALTYIDEVHAVGMYGKHGGGITEEMDLVD 235
254780604 157 IWNHNDLEDLEKNLAATDlSIPKIIIFESIYSMDGDIAPIKEICDLADQYNAITYIDEVHAVGIHGSCGAGISEREGIMN 236
294083651 157 IFRHNDVAHLESLLASQPlDRPKIIIFESVYSMDGDISPIADIIDLAKRYNALTYLDEVHAVGMYGTDGGGIAQMLGLDN 236
217977351 239 RIDVIEGTLAKGFGTLGGYITGEASIIDAVRSYAPSFIFTTSLPPAIATAAKTAVSLLKQGegAELRARHQRQSMLTKHA 318
163855632 235 KVDIIQGTMAKAIGVIGGYITGAQWLIDAVRSFSTGFIFTTSLPPVVAAGCLASIEHLKTQ--SQERELLHTKTQQLRQA 312
34496258  245 RATFIQGVFGKAMGTLGGYIAGPASVVDFVRSSAPGFIFTTALPQALLDATLCSFERVRED--RQLVQDLHSNVIFFRAQ 322
82751601  189 DIDIIQSTMAKGIGIIGGYITGDQLLIDVIRSYSSGFIFTTALPPVIAAGCLTSIKIVRSN--DKLREELQDKTKYLKEK 266
182439088 247 RATFVQGVFGKAVGATGGYVAGPDVPLDYTRSHAPGFIFTTTIPRASLDAALASLSVIRSPegAGMRERLHANAELMRRR 326
271970401 240 RPTFVQGVFGKAIGTVGGYVAGPDAALDYVRSYAPGFIFTTSLPQACMDATLKGLELVRHG--TDLRRALTDNSLRMKAA 317
254797163 236 RVDIIQGTLAKAYGVIGGYIAAKADIIDVVRSHASGFIFTTALPPVIASAGRASITHLYDS--NEERRKQKENVAKLKAM 313
88608338  236 RVDIIQGTLAKAYGVIGGYIAAKADIIDIIRSHASGFIFTTALPPVIASAGRASITHLYDS--DEERRKQKENVAKLKAM 313
254780604 237 RITIISGTLAKGFGTFGGYIAASENLCDFIRSFASGFIFSTSLPPAIASASVTSIQYIKQH--YDERKKYLERVKQLRHS 314
294083651 237 DIDIIQGTLGKAFGTIGGYIAADDVICDAVRSYGSGFIFSTALPPAIASTALASVRHIRAH--DKPRNQQKIQAEKLKAA 314
217977351 319 LSAAGLPVMP-NSSHIVPVLVGDAELCKAATDMLLDRHAIYIQPINYPTVAKGTERLRITPSPLHSDAHIAHLVESLVDV 397
163855632 313 LDSLDIPVMScSSTHVLPVLVGDAIKCKEAAERLLSVHGVYLQPINFPSVAAGTERFRVNVTPNHTDEQVTHLAEALREV 392
34496258  323 LDAAGIPYLP-AQSHLVLVPVAGAERIKTVARRLLEEFDIYVQPINYPSVPRGGERFRLTVGPRRSHEEIQRFVAALKHC 401
82751601  267 FKENGIEVLKqSKTHILPVIIGDSKKCEEAAKLLLGKFNIYDQAINSPTVEIGTERFRINVTPNHTKEQMDLLVSSIVYV 346
182439088 327 LTEAGIAHVP-APTHLVPILVPGGNRVKRVSRRLLDEHSVYVQPINFPSVPKGGERFRVTVAPFRTEAQIEGFVEALARC 405
271970401 318 LRSADIPFID-GEHHIIPVMVPGGDRVRKVADLLLEDHLIYVQPINFPSVPLGTERLRVTVAPYRTGDQIEYFAYALESC 396
254797163 314 FKANSIPYKD-APTHIIPVIIGHPEECKYASQTLLEEFKIFIQHINYPTVPRGTERLRITPTPQHTHTMMEELVFALKEV 392
88608338  314 FKANGIPYKD-APTHIIPVIIGHPEECKYASKTLLEEFKIFIQHINYPTVPRGTERLRITPTPQHTDTMMEELVFALKEV 392
254780604 315 LENKAIPCIP-NESHIIPIMVGDSHKCTQISNILLKEFGIYIQPINYPTVAKKKERLRVTLTPLHTDSDIEHLVSSLENV 393
294083651 315 LRATQIEFLD-GPTHIVPVMIGDAATCTRVCRLLLDDYNIYVQPINYPTVAKGTERLRLTPGPFHADAMIAHLVNALENA 393
217977351 398 WASLKLPFVEQPN 410
163855632 393 FEHFDIPLKTPPA 405
34496258  402 LA----------- 403
82751601  347 FDFLNIRRSV--- 356
182439088 406 Laddps------- 411
271970401 397 LARA--------- 400
254797163 393 LGRIQHKKSARGA 405
88608338  393 LGRIQHKKSARGA 405
254780604 394 WQKMNRYA----- 401
294083651 394 ISRATAESDQARQ 406
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap