2829736 88 VEDVDVCIVGAGPAGLSAAIRIKQQAakanrdIRVVVLEKAAEPGNHSVSGAVIQPTALDELLPNWRDDppeNCTAVTHD 167 fission yeast 14601521 1 ---------------------MASTG------LRVDLYEEHGRVGMPEHCTGIVSERTVNTIGREARET---IIDSYDSL 50 Aeropyrum pernix 20091714 1 -MKYDVVVVGAGPVGSTAARYAAMNG------AKVLLLEEHSSIGSPVGCTGLLSTRAVEECELRPSDEf--VFNSVRGA 71 Methanosarcina acet... 15678752 1 MTDYDVLIMGAGPAGSTLARLTATKG------FRVGLFERKKIIGLPLQC-AGLVSHRIMEVNVLPDEF---ILNSVRGA 70 Methanothermobacter... 14521810 1 -MNYDALIIGGGPVGNYLASLLAGK-------MSVAVVERKGAFGG-KACTGIIGAENYESLGLPDKA------ILNAFK 65 Pyrococcus abyssi 18312059 1 ---MKIAVIGAGPAGLSFASRYGDVD--------VY--EEHGEVGLPRHCTSLVSAISAEGLGLPKSl----VLVKYREL 63 Pyrobaculum aerophilum 14590266 1 -MRYDVLIIGGGPVGNYLASLLAGK-------VNVGVIEKKGAFGG-KACTGIVGAENYESLGLPEKA------ILNAFN 65 Pyrococcus horikoshii 13542326 1 --MKDVIVIGAGPSGSYAAYRLSKMG------LDVLLLEEHKEVGKPVECTGLVSKRVLDFVKTRSIA------GKVYGA 66 Thermoplasma volcanium 16082457 1 --MKDVIVIGAGPSGSFAAYRLAKAG------FTVDILEEHREVGKPVECTGLVSQRVLKYVRTKSIA------GTVRGA 66 Thermoplasma acidop... 15791367 1 -MMYDFVVVGVGPAGARFARRAAQQG------YDVIAFEQ-GDLGTPLAC-SGHVSLDVWEFVPDEHHDa-lFQNDIRGA 70 Halobacterium sp. N...
2829736 168 KMKFL--IPKLHFPIPvppamknhG-NYVMSLAEFTRWLAAKAEEYGVEIYPSFAASEVLYNKDGSVIGVATNDfgvdsk 244 fission yeast 14601521 51 EIRFR--GETLAVLDVg--------tVYRLDRVRLEELLLESLMSLGGRAQLGKRVHSVGIEGSVKAGGS---------- 110 Aeropyrum pernix 20091714 72 FVHAPd-GQCLPIDGKk-------TkAYVISRKNFDRTLAVMAVEEGVELSLKTRAVGLEKENFDAETGTKRNGngke-- 141 Methanosarcina acet... 15678752 71 VLHSPs-GIKLRVSKDr-------PeAHVIDRTAYDQHLAELAMEAGAELTKGTAVRDFN-------------------- 122 Methanothermobacter... 14521810 66 GAFFIskTKVFEIHRQv-------PqAYLVDRKVLERELAKRAIKRGADYYLATNFVGFK--DGKAILQHLDSR------ 130 Pyrococcus abyssi 18312059 64 RITDLe-GRQIYFNVR--------GgVYLIDRPGLEQWLASRTSRLLLGKRVVDLKNGYVYTSDGERRG----------- 123 Pyrobaculum aerophilum 14590266 66 GAFFIsrEKVFEIHRSl-------PqAYLIDRKVLERELAKRAMRKGAEYYLSTNFLGFK--NGKAILQHLDSR------ 130 Pyrococcus horikoshii 13542326 67 NIYFPn-gKSIHVEKNd-------EtIVLY-RDSFDKDVAAMAIGAGADIRINARAISVKENNDSVTVKYRDSGq----- 132 Thermoplasma volcanium 16082457 67 NIFFPn-gKSVHIEKDd-------PtIVLF-RDAFDKDVAAMAIGAGSGIRINARALSVTEHDDHVTVRYRENGs----- 132 Thermoplasma acidop... 15791367 71 RFHLG--GADSSAHPFyk----stPiSNAIDRVHLDEVLAEAARDAGADVREHHTVTDVTEHRNRVTVTARGPDd----- 139 Halobacterium sp. N...
2829736 245 glpkdnfergMAFHAPVTLFAEGAHGSLSKSIIKRfnlrgNCEPQTYGLGVKEVWRVPde---nfRKGEVAHTLGWPMRN 321 fission yeast 14601521 111 -----------EARYDAVILADGAHGELHRMLDLG---------YRGDYYYGLNILVP--------GKRESTILVDFILD 162 Aeropyrum pernix 20091714 142 ------ngnkKNSPVKLKVLRNGKPETISTSVVIGadgvkSRIASHAGLGKPARILPGiqieapyTSDDSDFVELFPGSS 215 Methanosarcina acet... 15678752 123 -----------EKTGHVRVNGDELSADVLVDARGQ-----SAAPSRYPARQYLVRFRD-------SEMDTDFVDLKVDSR 179 Methanothermobacter... 14521810 131 ----------FEIKAKYYVGADGVNSKVAQEIGAKt----rG--EVLRGWELEVLGNFr------R-EWVEVWVNK--DI 185 Pyrococcus abyssi 18312059 124 -------------PYDYIVLAEGSLRKFSARFGHV------VRLPGLQVDIKSSVDLP------------GINVVYNNKL 172 Pyrobaculum aerophilum 14590266 131 ----------LEIEAKYYVGADGVNSSVAKEIQARt----eG--EVLKGWEIEVLGNFk------R-DHVEVWVNK--NI 185 Pyrococcus horikoshii 13542326 133 ---------lKEDNAKVVIGADGINSVVRRDLYRIr----qE--KVVSTLQYDMAGKIe------DERSVNVYLGS--KY 189 Thermoplasma volcanium 16082457 133 ---------iKEEDARIVIGADGINSVVRRDVYGMr----qK--HVVSTLQYDMASGIe------DEDSVNVYLGS--QY 189 Thermoplasma acidop... 15791367 140 ---------sIDVTAKMVAGSDGPRSRVRDALSLP-------EPDEFLHGALAFDPDP-----------DHQDFVDVHLT 192 Halobacterium sp. N...
2829736 322 DTYGGGFMYQFGDNYVTVGLVVGLDYp--nPYVSPA--LEFQRMKQNPFFAKVLKGGKCLEYAARALNEGGYQAIPkLVF 397 fission yeast 14601521 163 RGLAFTWDVPTVGSVSVAGAMGTLAG--------------VKRFFEVLKP-------RAFKVYGGRIPAGPPAER--LRR 219 Aeropyrum pernix 20091714 216 APGFFAWTVPLNEKVSRIGLALDSGLagksGPGGSSplFYLEKLLCSNPHIKARYSDGMLDFVVGGIPVGPQGRT---FS 292 Methanosarcina acet... 15678752 180 LSPGFMWRIPIDEQTARVGVFGPQQNl--kEFLKGFisDLSSDF-------------EILESHHGFIPRPDLDLR--LVR 242 Methanothermobacter... 14521810 186 NPEFFFWVAPINEEEARIGTFGDVESl--aKFLK------VRRINPS----------NVLEIKSGAVVLG-WRSP--WVK 244 Pyrococcus abyssi 18312059 173 SRAYFSWIVEIDRGVYRVGLADVCCT------VEKLn-KLVKLLRGAP----------ISKPFGGGVLAGPPLRR--LTH 233 Pyrobaculum aerophilum 14590266 186 NPEFFFWVAPINEEEARVGTFGEIDSl--aKFLK------IRRLNPF----------KTVEIKSGAVILG-WRKP--WVK 244 Pyrococcus horikoshii 13542326 190 THGFFGWAVPGGE-IIRVGTGSYRASa--yPYMKA----LSKRFGTN----------RVLGITGAGIPIK-IAKS--LFT 249 Thermoplasma volcanium 16082457 190 THGFFGWAVPGGD-IVRVGTGSYKASa--rPYMDN----LSRRFGDN----------RTLGITGAGIPIR-MAER--LSS 249 Thermoplasma acidop... 15791367 193 VPGFFAWRIPRGDAGVEYGLAAAPGE-----DVAGRfdDLVADYG-----------VDVEHRCSGLIPIGPPDTVT---S 253 Halobacterium sp. N...
2829736 398 PGGALIGCSAGFVNVAKIKGTHTAMKSGIVAADAIVDAF-Grda-------asKPLLLNd------YEENLKNTYVFKEL 463 fission yeast 14601521 220 GRVYVVGDAGGLVKPLSGGGLYPNAKAAKLAASLIKRGLdVgealekslsivsHELRAQhavarlvYGTRVLETISRAVG 299 Aeropyrum pernix 20091714 293 DGILLAGDAAGQAKPTSAGGVYTGAFAAKIAGKIAAEAAlEgd--------nsARRLSE-------YDRLWRKGLEKELE 357 Methanosarcina acet... 15678752 243 GRCILLGDAAGQVKPTTGGGIVLASRAAGVAAEVIQGVLeGd------------aDLKE-------YEDACRKIHMSEMK 303 Methanothermobacter... 14521810 245 DNVALVGDAALHIKPTTAGGIVFGSYCARALAKAILNGNlAey----------eKNCSWv------KEQVKFGLRIRKVF 308 Pyrococcus abyssi 18312059 234 GRYITVGDAAGLVKPLSGGGIILALKSGALAAMALDKGDiQr------------yEAAT-------LYTRLRLRAAFSLF 294 Pyrobaculum aerophilum 14590266 245 GNVALVGDAALQIKPTTAGGIVFGAYCAKSLAKAILNDNlEiy----------eRECSWv------REQVSFGLKIRKVF 308 Pyrococcus horikoshii 13542326 250 KRSVLIGDAGGIVKPLSGGGIYTGIFSANLASERVANAIeNe-----------dYSQLRh------YDKDIRGSIGVELK 312 Thermoplasma volcanium 16082457 250 RRTVLVGDAGGIVKPLSGGGIYTGIFSSDVAANYVVEALeSds----------sEASLRk------YDREIRNTIGKELK 313 Thermoplasma acidop... 15791367 254 HRGFLLGDAAGQTKPFTGGGIRYGMTAADAAARELDPDRpG--------------TLAG-------YERAWRDALEREIT 312 Halobacterium sp. N...
2829736 464 YSVRNIRPSFHsflgNYGGMAYSAVEAYVLkgrvpwtlkhkgGDAKATKSASKYKPINYPKPDNVLS-FDIPTSVSRSAT 542 fission yeast 14601521 300 GAPLRLRLDYDthhqLVISTLSQVGALSSQr-----------LAAAALRGGGLEAPLSLVKVLYHSSaSAYKRLASGRLP 368 Aeropyrum pernix 20091714 358 IGMKIHDYMGK----LEDNQLNELIGSLNTps---------iLNTITEYGDMDHPSVLVRKLMFSGNsLRLVKAFGTFLK 424 Methanosarcina acet... 15678752 304 NQMRVQRTFRL----LSDKDLDHIFLKMKEyg---------aEDIISEYGDMDRQTPLIREFLKRGIlFRIIPSILTSKV 370 Methanothermobacter... 14521810 309 KSLTQKEIEEI----FEVLGSEDARKLIIE------------KADFDDHVK--TAKALLRNPR---LlARLIRIAPIILR 367 Pyrococcus abyssi 18312059 295 RILYGMRLVDR-----LLQILNGGEYVAVD-------------YDDHVKSLLVAALTDARSIMAAKEvARYLASKALS-- 354 Pyrobaculum aerophilum 14590266 309 KNLTQEKIEEI----FEVLSSEEVRKIIVE------------RADFDDHVK--TVKALLKNPR---VlAKLIRISPIILR 367 Pyrococcus horikoshii 13542326 313 KDGFIQSIYSK----IGDRSFDRIYGLISS------------EKIIDTINR--SGDIDYPSKV---IfKVLIRNPALLYS 371 Thermoplasma volcanium 16082457 314 KDAMIQRIYSR----ISDRSFNRIYSMISN------------EKIIDVINR--SGDIDYPSTV---IiKVLLRNPGILYS 372 Thermoplasma acidop... 15791367 313 LGHLVRAGYS-----MPTPIQSAGLRLFSGe----------iAVDMDKPTSLFSLDQARALLR----------------- 360 Halobacterium sp. N...
2829736 543 MH 544 fission yeast 14601521 369 GV 370 Aeropyrum pernix 20091714 425 TL 426 Methanosarcina acetivorans C2A 15678752 371 AG 372 Methanothermobacter thermautotrophicus str. Delta H 14521810 368 TL 369 Pyrococcus abyssi 18312059 -- Pyrobaculum aerophilum 14590266 368 AL 369 Pyrococcus horikoshii 13542326 372 MW 373 Thermoplasma volcanium 16082457 373 MW 374 Thermoplasma acidophilum 15791367 -- Halobacterium sp. NRC-1
Jiyao W et al.(2023). "The conserved domain database in 2023.",