Conserved Protein Domain Family
TypA

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COG1217: TypA (this model, PSSM-Id:224138 is obsolete and has been replaced by 440830)
Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]
Statistics
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PSSM-Id: 224138
Aligned: 40 rows
Threshold Bit Score: 977.103
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
15837815  39 SIENLRNIAIVAHVDHGKTTLVDQLLKQSGTFSERTQVGERVMDSNDQEKERGITILAKNTAINWNG-------NRINIV 111 Xylella fastidiosa ...
19552324   2 THPEFRNVAIVAHVDHGKTTLVNAMLEQSGVFSDHGEVADRVMDSGDLEKEKGITILAKNTAIRRKGagkdgndLIINVI 81  Corynebacterium glu...
15673997   7 LREDIRNVAVIAHVDHGKTTLVDELLKQSQTLDARKELAERAMDSNALEQERGITILAKNTAVEYNG-------TRINIL 79  Lactococcus lactis ...
15827789   1 --MPFRNVAIVAHVDHGKTTLVDAMLRQSGALHERGQVQERVMDTGDLEREKGITILAKNTAVHCHNsdg--tvTVINVI 76  Mycobacterium leprae
15840608   1 --MPFRNVAIVAHVDHGKTTLVDAMLRQSGALRERGELQERVMDTGDLEREKGITILAKNTAVHRHHpdg--tvTVINVI 76  Mycobacterium tuber...
15608305   1 --MPFRNVAIVAHVDHGKTTLVDAMLRQSGALRERGELQERVMDTGDLEREKGITILAKNTAVHRHHpdg--tvTVINVI 76  Mycobacterium tuber...
15926694   4 KREDVRNIAIIAHVDHGKTTLVDELLKQSGIFRENEHVDERAMDSNDIERERGITILAKNTAVDYKG-------TRINIL 76  Staphylococcus aure...
15900582   4 LREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAERAMDSNDIEKERGITILAKNTAVAYNG-------TRINIM 76  Streptococcus pneum...
15675426   4 LRNDIRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQERAMDSNDLEKERGITILAKNTAVAYND-------VRINIM 76  Streptococcus pyoge...
16800124   3 LRNDIRNVAIIAHVDHGKTTLVDQLLRQSGTFRDNETVAERAMDNNDLERERGITILAKNTAIKYED-------TRVNIM 75  Listeria innocua
15837815 112 DTPGHADFGGEVERVLSMVDSVLLLVDAMDGPMPQTRFVTQKAFAMGFKPIVVVNKIDRPGARPDWVVEQVWDLFDRLGA 191 Xylella fastidiosa ...
19552324  82 DTPGHADFGGEVERALSMVDGVVLLVDASEGPLPQTRFVLGKALAAKMPVIIAVNKTDRPDARIDEVVEEAQDLLLELAS 161 Corynebacterium glu...
15673997  80 DTPGHADFGGEVERIMKMVDGVVLVVDAYEGTMPQTRFVLKKALEQNLTPIVVVNKIDKPSARPAEVVDEVLELFIELGA 159 Lactococcus lactis ...
15827789  77 DTPGHADFGGEVERGLSMVDGVLLLVDASEGPLPQTRFVLRKTLAAHLPVILVVNKTDRPDARIAEVVEASHDLLLDVAS 156 Mycobacterium leprae
15840608  77 DTPGHADFGGEVERGLSMVDGVLLLVDASEGPLPQTRFVLRKALAAHLPVILVVNKTDRPDARIAEVVDASHDLLLDVAS 156 Mycobacterium tuber...
15608305  77 DTPGHADFGGEVERGLSMVDGVLLLVDASEGPLPQTRFVLRKALAAHLPVILVVNKTDRPDARIAEVVDASHDLLLDVAS 156 Mycobacterium tuber...
15926694  77 DTPGHADFGGEVERIMKMVDGVVLVVDAYEGTMPQTRFVLKKALEQNLKPVVVVNKIDKPSARPEGVVDEVLDLFIELEA 156 Staphylococcus aure...
15900582  77 DTPGHADFGGEVERIMKMVDGVVLVVDAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGA 156 Streptococcus pneum...
15675426  77 DTPGHADFGGEVERIMKMVDGVVLVVDAYEGTMPQTRFVLKKALEQNLIPIVVVNKIDKPSARPAEVVDEVLELFIELGA 156 Streptococcus pyoge...
16800124  76 DTPGHADFGGEVERIMKMVDGVLLVVDAYEGTMPQTRFVLKKALEQNLTPIVVVNKIDRDFARPEEVVDEVLELFIELGA 155 Listeria innocua
15837815 192 TPEQ----------MDFPIVYASALNGYASL--ESSARAGD----MNPLYEAIMQHVQPPQVDLHGPFQMRISQLDYNSY 255 Xylella fastidiosa ...
19552324 162 ALDDeeaaqaaeqlLDLPVLYTSGREGKASTe-NPGNGNVPnspdLMPLFETLYEVLPEPTADIDGPLQAHVTNLDSSSF 240 Corynebacterium glu...
15673997 160 DDEQ----------LDFPVVYASAINGSSSMsdNPADQEHT----MANIFDTIIDHIPGPVdNSDEPLQFQVSLLDYNDY 225 Lactococcus lactis ...
15827789 157 DLDEeaaaa-aeraLGLPTLYASGRAGIASTe-QPADGAVPtgdnLDPLFDVLMEHIPSPKGDPEAPLQALVTNLDASAF 234 Mycobacterium leprae
15840608 157 DLDDeaaaa-aehaLGLPTLYASGRAGVASTt-APPDGQVPdgtnLDPLFEVLEKHVPPPKGEPDAPLQALVTNLDASTF 234 Mycobacterium tuber...
15608305 157 DLDDeaaaa-aehaLGLPTLYASGRAGVASTt-APPDGQVPdgtnLDPLFEVLEKHVPPPKGEPDAPLQALVTNLDASTF 234 Mycobacterium tuber...
15926694 157 NDEQ----------LEFPVVYASAVNGTASL--DPEKQDDN----LQSLYETIIDYVPAPIdNSDEPLQFQVALLDYNDY 220 Staphylococcus aure...
15900582 157 DDDQ----------LDFPVVYASAINGTSSLsdDPADQEAT----MAPIFDTIIDHIPAPVdNSDEPLQFQVSLLDYNDF 222 Streptococcus pneum...
15675426 157 DDEQ----------LEFPVVYASAINGTSSLsdDPADQEHT----MAPIFDTIIDHIPAPVdNSDEPLQFQVSLLDYNDF 222 Streptococcus pyoge...
16800124 156 NDDQ----------LEFPVVYASAINGTSSFesDPAEQKET----MKPLLDTIIEHIPAPVdNSDEPLQFQVSLLDYNDY 221 Listeria innocua
15837815 256 VGLIGIGRIQRGKVSTNMPVTVID----RMGNKHNGKVLQVLGFLGLERHEVEEAQAGDIVAISGIESLSISDTLTDPTS 331 Xylella fastidiosa ...
19552324 241 LGRIGLVRVHAGTLRKGQQVAWIHydeeGNQHTKTAKIAELLATVGVARVPATEVVAGDIAAISGIEDIMIGDTLADPEN 320 Corynebacterium glu...
15673997 226 VGRIGIGRVFRGTIKVGDSVTLSK----LDGSTKNFRVTKLFGFFGLDRQEIQEAKAGDLIALSGMEDIFVGETVTPSDH 301 Lactococcus lactis ...
15827789 235 LGRLALVRIYNGKLRKGQQVAWMRev-dGLPVTTDAKITELLVTKGVERSTTEEATAGDIVAVAGLPEIMIGDTLADPEH 313 Mycobacterium leprae
15840608 235 LGRLALIRIYNGRIRKGQQVAWIRqv-dGQQTVTTAKITELLATEGVERKPTDAAVAGDIVAVAGLPEIMIGDTLAASAN 313 Mycobacterium tuber...
15608305 235 LGRLALIRIYNGRIRKGQQVAWIRqv-dGQQTVTTAKITELLATEGVERKPTDAAVAGDIVAVAGLPEIMIGDTLAASAN 313 Mycobacterium tuber...
15926694 221 VGRIGIGRVFRGKMRVGDNVSLIK----LDGTVKNFRVTKIFGYFGLKRLEIEEAQAGDLIAVSGMEDINVGETVTPHDH 296 Staphylococcus aure...
15900582 223 VGRIGIGRVFRGTVKVGDQVTLSK----LDGTTKNFRVTKLFGFFGLERREIQEAKAGDLIAVSGMEDIFVGETITPTDA 298 Streptococcus pneum...
15675426 223 VGRIGIGRVFRGTVKVGDQVTLSK----LDGTTKNFRVTKLFGFFGLERREIQEAKAGDLIAVSGMEDIFVGETITPTDC 298 Streptococcus pyoge...
16800124 222 VGRIGIGRVFRGTMHVGQTVALIK----LDGTVKQFRVTKMFGFFGLKRDEIKEAKAGDLVALAGMEDIFVGETVTPFDH 297 Listeria innocua
15837815 332 PDALPALSVDEPTISMTFQVNNSPFAGQKeysgGKFLTSRQIRERLARETLHNVALRVEDTEDPDRFKVSGRGELHLSVL 411 Xylella fastidiosa ...
19552324 321 PVALPRITVDEPALSMTIGVNTSPMAGRGg---GDKLTARVVKARLENELIGNVSLKVNPTERPDTWEVQGRGEMALSIL 397 Corynebacterium glu...
15673997 302 VEPLPILHIDEPTLQMTFLANNSPFAGRE----GKWVTSRKVEERLVSELQTDVSLRVENTESPDKWVVSGRGELHLSIL 377 Lactococcus lactis ...
15827789 314 AHALPRITVDEPAISVTIGTNTSPLAGKVs---GHKLTARMVRGRLDAELVGNISIRVVDIGRPDAWEVQGRGELALAVL 390 Mycobacterium leprae
15840608 314 PVALPRITVDEPAISVTIGTNTSPLAGKVg---GHKLTARMVRSRLDAELVGNVSIRVVDIGAPDAWEVQGRGELALAVL 390 Mycobacterium tuber...
15608305 314 PVALPRITVDEPAISVTIGTNTSPLAGKVg---GHKLTARMVRSRLDAELVGNVSIRVVDIGAPDAWEVQGRGELALAVL 390 Mycobacterium tuber...
15926694 297 QEALPVLRIDEPTLEMTFKVNNSPFAGRE----GDFVTARQIQERLNQQLETDVSLKVSNTDSPDTWVVAGRGELHLSIL 372 Staphylococcus aure...
15900582 299 VEALPILHIDEPTLQMTFLVNNSPFAGKE----GKWVTSRKVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSIL 374 Streptococcus pneum...
15675426 299 VEALPILRIDEPTLQMTFLVNNSPFAGRE----GKWITSRKVEERLLAELQTDVSLRVDPTDSPDKWTVSGRGELHLSIL 374 Streptococcus pyoge...
16800124 298 QEALPLLRIDEPTLQMTFVTNNSPFAGRE----GKHVTSRKIEERLLAELQTDVSLRVEPTASPDAWVVSGRGELHLSIL 373 Listeria innocua
15837815 412 IETMRREGYELGVSRPEVIIKEIDGILQEPYEQLVVDVEEEHQGGVIERLGTRKAQLSNMELDGKG--RVRLDYIIPARG 489 Xylella fastidiosa ...
19552324 398 VETMRREGFELTVGKPQVVTQTIDGKLHEPYEIIVIDVPSEYQGNVTQLLATRKGLMQSMS-TTPGsdWIRMEFRIPARG 476 Corynebacterium glu...
15673997 378 IETMRREGYELQVSRPEVIIKEIDGVACEPFERVQIDTPEEYQGSIIQALSERKGDMLDMQITGNG--QARLIFLVPARG 455 Lactococcus lactis ...
15827789 391 VETMRREGFELTVGKPQVVTRTIDGKLHEPFEVMTIDCPEEFVGAITQLMAGRKGRMEEMANHAVG--WVRMDFIVPSRG 468 Mycobacterium leprae
15840608 391 VEQMRREGFELTVGKPQVVTKTIDGTLHEPFESMTVDCPEEYIGAVTQLMAARKGRMVEMANHTTG--WVRMDFVVPSRG 468 Mycobacterium tuber...
15608305 391 VEQMRREGFELTVGKPQVVTKTIDGTLHEPFESMTVDCPEEYIGAVTQLMAARKGRMVEMANHTTG--WVRMDFVVPSRG 468 Mycobacterium tuber...
15926694 373 IENMRREGYELQVSKPQVIIKEIDGVMCEPFERVQCEVPQENAGAVIESLGARKGEMVDMTTTDNG--LTRLIFNVPARG 450 Staphylococcus aure...
15900582 375 IETMRREGYELQVSRPEVIVKEIDGIKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNG--QTRLVFLVPARG 452 Streptococcus pneum...
15675426 375 IETMRREGYELQVSRPEVIIKEIDGVKCEPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNG--QTRLIFLIPARG 452 Streptococcus pyoge...
16800124 374 IETMRREGYELQVSKPEVIIREIDGVKCEPVEDVQIDTPEEFMGSVIESISQRKGEMKNMINDGNG--QVRLQFMVPARG 451 Listeria innocua
15837815 490 LIGFQTEFKTITSGSGLLFHIFDHYGPKADgPIAKRINGVMISNGHGKAPGYALMGLQERGRLLIDAGEDIYEGMLVGIH 569 Xylella fastidiosa ...
19552324 477 LIGFRTQFMTETRGTGIANSYSDGMDVWAG-EIKGRAHGSLVADRSGQITAYALTQLADRGSFFVEPGTETYEGVVVGLN 555 Corynebacterium glu...
15673997 456 LIGFTTEFMSMTRGYGIMNHTFDQYLPAVKgEIGGRHRGSLISMDSGQVTSYAMGYVQERGQLFVDAGTEVYGGMIVGEH 535 Lactococcus lactis ...
15827789 469 LIGFRTDFLTLTRGTGIANAVFDSYRPWAG-EIRARDTGSLVSDRPGTITPFALLQLADRGQFFVSPGQDTYQGMVVGIN 547 Mycobacterium leprae
15840608 469 LIGWRTDFLTETRGSGVGHAVFDGYRPWAG-EIRARHTGSLVSDRAGAITPFALLQLADRGQFFVEPGQQTYEGMVVGIN 547 Mycobacterium tuber...
15608305 469 LIGWRTDFLTETRGSGVGHAVFDGYRPWAG-EIRARHTGSLVSDRAGAITPFALLQLADRGQFFVEPGQQTYEGMVVGIN 547 Mycobacterium tuber...
15926694 451 MIGYTTEFMSMTRGYGIINHTFEEFRPRIKaQIGGRRNGALISMDQGSASTYAILGLEDRGVNFMEPGTEVYEGMIVGEH 530 Staphylococcus aure...
15900582 453 LIGYSTEFLSMTRGYGIMNHTFDQYLPLIPgEIGGRHRGALVSIDAGKATTYSIMSIEERGTIFVNPGTEVYEGMIIGEN 532 Streptococcus pneum...
15675426 453 LIGYSTEFLSMTRGYGIMNHTFDQYLPVVQgEIGGRHRGALVSIENGKATTYSIMRIEERGTIFVNPGTEVYEGMIVGEN 532 Streptococcus pyoge...
16800124 452 LIGYTTDFLSMTRGYGIINHTFDSYQPIQKgRVGGRSRGVLVSMETGKSTTYGTMQVEDRGTIFVEPGTDIYEGMIVGEN 531 Listeria innocua
15837815 570 SKDNDLTVNALREKQLTNIRAAGKDDAISLTPPIKMSLEQALEFIEDDELVEVTPKAIRLRKKYLSENDRKRASRTG 646 Xylella fastidiosa 9a5c
19552324 556 NREEDMDINPTKEKKLTNMRAASADTTVTLAKARSLSLDEALEFCGVDECVEVTPDVLRIRKVILNATERGRARSRA 632 Corynebacterium glutam...
15673997 536 SRDNDLTVNITKMKQQTNVRSSNKDSTSVLNTPKILSLEESLEFLGDDDYLEVTPESIRLRKQILDKAMREKSTKKK 612 Lactococcus lactis sub...
15827789 548 PRPEDLDINVTREKKLTNMRSSTANVIETLTKPLELDLERAMEFCSFDECVEVTPEIVRVRKIELESNARARGRARA 624 Mycobacterium leprae
15840608 548 PRPEDLDINVTREKKLTNMRSSTADVIETLAKPLQLDLERAMELCAPDECVEVTPEIVRIRKVELAAAARARSRART 624 Mycobacterium tubercul...
15608305 548 PRPEDLDINVTREKKLTNMRSSTADVIETLAKPLQLDLERAMELCAPDECVEVTPEIVRIRKVELAAAARARSRART 624 Mycobacterium tubercul...
15926694 531 NRENDLTVNITKTKHQTNVRSATKDQTQTMNRPRILTLEEALQFINDDELVEVTPESIRLRKKILNKNVREKEAKRI 607 Staphylococcus aureus ...
15900582 533 SRENDLTVNITKAKQMTNVRSATKDQTAVIKTPRILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKK 609 Streptococcus pneumoni...
15675426 533 SRDNDLGVNITTAKQMTNVRSATKDQTAVIKTPRILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAARDKANKKK 609 Streptococcus pyogenes...
16800124 532 NREGDIAVNIVKAKQMTNIRSANKDQTNVIKKPRHLSLEESLEFLNEDEYCEVTPESIRLRKKILNKNEREKAAKRS 608 Listeria innocua
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