Conserved Protein Domain Family
cpxA

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PRK09470: cpxA 
envelope stress sensor histidine kinase CpxA
Statistics
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PSSM-Id: 236532
Aligned: 121 rows
Threshold Bit Score: 608.855
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
152978458   7 RINRLPVQLLASFWLViFTTLSITFVLLHFLDSHRPEKLESEEL------R---TYHKQILSVYRTNQ--VYRILGFAKN 75 
37681298    5 KITSLYGRIFAIFWFT-MFLVLMAVLALPHLDPRKARNIPADQY------DrfiEAKQEIEKQYRGET--DLGRILF-RM 74 
27364654    5 KITSLYGRIFAIFWFT-MFLVLMAVLALPHLDPRKARNIPADQY------DrfiEAKQEIEKQYRGET--DLGRILF-RM 74 
190149942  15 VRNYLAYQLFAYFGLT-FAILLAITLAIPNFDARSFLPIETDERd--------fFQQESHSTEMQYNL----DEIFERKL 81 
165976043  15 VRNYLAYQLFAYFGLT-FAILLAITLAIPNFDARSFLPIETDERd--------fFQQESHSTEMQYNL----DEIFERKL 81 
33152530   11 VRNYLAYQLFAYFGLT-FAIMLAITLAIPNFDARSFSRLEKGEHe--------fFIQESRQTELQYNL----DEIFERRL 77 
15603753    8 FFNTISFRIFAFFWLT-FSLLSILIFSIPYFDSRIYSELSEKELs---------AYQQEIITSIRHNQ--------IARI 69 
152995591   5 KITSLYGRIFAIFWFT-MFLVVLAVLALPHFDPRKPRDIPPPHY------DrmlQIRDQVERNFASAP--D-----LAKV 70 
251793483   7 IFNSLTIRIFTFFWLT-FSILLIFIFLLPYFDAHIYSNLKEYEVakyqkeIttsIRNNQISRILAGVPvfPND------- 78 
261867363   7 IFNSLTIRIFTFFWLT-FSILLIFIFLLPYFDAHIYSDLKEHEMvkyqkeIttsMRNNQISRILAGIPsfPND------- 78 
152978458  76 PLPAEETRD----LH----A-VLFNP---DTQEIA---G-TSAE--EHSDVRNFIFRSNDFSNPMIQVVNERRIAGPFSV 137
37681298   75 ERPGDRHGR----DG----RpRFFITd--YDGNIL---TtLKQGdfQLKALKNFVTSIEQPDQPKQKLYGRFMLSGPLPV 141
27364654   75 ERPGDRHGR----DG----RpRFFITd--YDGNIL---TtLKQGdfQLKALKNFVTSIEQPDQPKQKLYGRFMLSGPLPV 141
190149942  82 SVATT--------NG----F-DVILLd-wKTGVFV---G-VDPH--TIKSFQVFLYRADSPAEPLQRRFGNLEIYGPFLV 141
165976043  82 SVATT--------NG----F-DVILLd-wKTGVFV---G-VDPH--TIKSFQVFLYRADSPAEPLQRRFGNLEIYGPFLV 141
33152530   78 SVATQ--------NG----F-NIILFd--PKTRIFvgaG-ADSN--RIQSFQVFLYRAQTPLEPLQRRFGSLEISGPFLV 139
15603753   70 LAGV-PLSHaerfDG----I-RPVLVddvDDSSIL---G-ATAT--EIPLLTQFMFSSSDPTRPLKKVFGDVRIVGPFSI 137
152995591  71 LHDLDGWSR----RGpddnKlRLFITd--LDGNVI---TtDRRPdfSYKALRNFVTSIDNPQDPQQKLYGKTMISGPLPI 141
251793483  79 -----RFSA------------HPVLIa--PSGQIL---G-ALPE--EEKSLRQFIFNNAVLEQPLKKIYSNIQIVGPFSL 133
261867363  79 -----RFTP------------HPVLIs--PSGQIL---G-ALTE--EEKSVRQFIFNNASLDQPLKKIYSNIQIVGPFSL 133
152978458 138 NInlinernepKDVAYLMYFVSPVD-THLVFLSYLFAHPFLIMLIIALASTPVLLLLAWRIGVPIKRFRQAAELVSLGQF 216
37681298  142 TL---------ANKEYLLYVGMRWNqPPP-FLLRMFDHPFQLLLAVMLVSTPLLLWLAWALSQPARRLEKAAQRVAKGEF 211
27364654  142 TL---------ANKEYLLYVGMRWNqPPP-FLLRMFDHPFQLLLAVMLVSTPLLLWLAWALSQPARRLEKAAQRVAKGEF 211
190149942 142 KS---------SKREYFQYFAQSVD-PQEELFNQIFDSPWLMLLIVLGVSIPILLWLSWKISRPVKALRLSANAVATGNF 211
165976043 142 KS---------SKREYFQYFAQSVD-PQEELFNQIFDSPWLMLLIVLGVSIPILLWLSWKISRPVKALRLSANAVATGNF 211
33152530  140 KS---------NKREYMQYFAQIVD-PQEEFFNRIFDSPWLMLMIVLIVSVPILLWLSWKIARPVKELRICANAVATGNL 209
15603753  138 HLgg------eANKSYTLYFIDRVN-AQKEIMSFVFANPALLVGLIILVSTPLLWWLARSIGKPIRNLQMSAKAVALGDF 210
152995591 142 RL---------AKKDYFLY-VGTRWsEPPHFLLQLFDHPFRLLLAVMLVSTPLLLWLAWALSQPARRLERAAQRVAQGVF 211
251793483 134 YLnp------eHNQSYSLYFVNQIN-AQKEILNYIFDRPFFLIVLVILISTPLLWWLSRSIGQPIHNLQLAANAVAIGNL 206
261867363 134 YLnp------eHNQSYSLYFVNQIN-AQKEILNYIFDRPFFLIILVILISTPLLWWLSRSIGQPIRNLQLAANAVAIGNL 206
152978458 217 VTNPDLENkGPMELRQVGKSLNHMTVSLAELLDTHQRLVSSISHELRTPLTRLQLAVALLRRRVGEYP-ETKRIETESER 295
37681298  212 VTDPSLEK-GTSEFRQAGASFNRMVEAVNQMISGQQRLLSDISHELRSPLTRLRMANALATRKQGESN-ELQRIDTEAQR 289
27364654  212 VTDPSLEK-GTSEFRQAGASFNRMVEAVNQMISGQQRLLSDISHELRSPLTRLRMANALATRKQGESN-ELQRIDTEAQR 289
190149942 212 AINPALETeGINELREVGKSFNQMITSLQDLTLHQQRLVSDISHELKTPLARLHLATALIRRRNGESP-ELTRIENQIQK 290
165976043 212 AINPALETeGINELREVGKSFNQMITSLQDLTLHQQRLVSDISHELKTPLARLHLATALIRRRNGESP-ELTRIENQIQK 290
33152530  210 AINPKLETeGIHEFREVGRSFNQMITSLQELTEYQQRLLSDISHELKTPLARLQLATALIRRRNGDSA-ELTRIDNQIMK 288
15603753  211 KINKDLETkGSLELRQVGQSFNQMTESLEELLSSQQVLLSSISHELRTPLTRLQLALALLRRRFGEDNtEIHRIEIEARR 290
152995591 212 EIDPGLEK-GTSEFRQAGASFNQMVTAVNLMITRQQRLLSDISHELRSPLTRLRMAQALAKRKLGDST-DLTRIDTEAQR 289
251793483 207 RINKDLETkGLLELRQVGQSFNRMMQSLEEVLLNQQSLLSSISHELRTPLTRLQLATALLRRKLGDSS-EIQRIDTEAQR 285
261867363 207 KINKNLETkGLIELRQVGQSFNRMMLSLEEVLSNQQSLLSSISHELRTPLTRLQLATALLRRRLGDSN-EIQRIDTEAQR 285
152978458 296 LDKMINDLLLLSRNQLRLQLERNYLTVDSIWNEVIEDAEFEAEHRKIDFTFIqliKHPERYSILGDREALASALENILRN 375
37681298  290 LEQMISELLELSRMQMNSHLDREEQPVASLWEEIIQDAQFEAEQMGKVLQYT----PLPERHISGNPKLLMSAIENIIRN 365
27364654  290 LEQMISELLELSRMQMNSHLDREEQPVASLWEEIIQDAQFEAEQMGKVLQYT----PLPERHISGNPKLLMSAIENIIRN 365
190149942 291 LDTMVHDLLVLSRQQVNQHLTREIFSINKIWDDLLEDAKFDAEQNHLDLFISqriTHPENFFINGNQNILASAMENVIRN 370
165976043 291 LDTMVHDLLVLSRQQVNQHLTREIFSINKIWDDLLEDAKFDAEQNHLDLFISqriTHPENFFINGNQNILASAMENVIRN 370
33152530  289 LDTMVHDLLSLSRQQINQHLMREVFSINKIWDDILEDAKFEAEQNQIDLFIEqriDNVEGYFINGNEIILASALENLIRN 368
15603753  291 LDKMINDLLLLSRQQLHSHVSREIFPINELWEEVLDDAIFEAEHRKLNFVVRqniTQPARYYVNGNKALLVSAIENIVRN 370
152995591 290 IEQMIGKLLELSSVQVDSHLNREVQPLSSLFDALLADSQFEAEHMGKTLLLS---AVPNR-MINCHPQLLMSALENIVRN 365
251793483 286 LDKMINDLLQLSRQQLHSHLEKNIFPIPTLWAEVLNDAEFEAAQRHIKFTVVqsiVHPETYYLNGNHGLLASAVENLIRN 365
261867363 286 LDKMVSDLLQLSRQQLNSHLEKDIFPIPLLWKEILEDAKFEAAQRNIRFHVEqgiAHPEQYYLNGNHGLLASAVENIVRN 365
152978458 376 ALKYTNNKIVALMTLKKSDLmMIIVDDNGAGVPEREYEQIFKPFYRVDEARTRTTGGTGLGLAIVVNTIQQHQGKVWAEK 455
37681298  366 AIYYGKDQVIIAIQAIDDTL-HIVVDDNGEGVPEEELEAIFRPFYRVSTARDRHSGGTGLGLSITESAIRQHSGTIKAER 444
27364654  366 AIYYGKDQVIIAIQAIDDTL-HIVVDDNGEGVPEEELEAIFRPFYRVSTARDRHSGGTGLGLSITESAIRQHSGTINAER 444
190149942 371 AQKYAKKSIKVLTYIDNTDL-IIAIDDDGKGIPETEYQQIFRPFYRVDEARDRQTGGTGLGLAIVANAVQQHKGSVQAMK 449
165976043 371 AQKYAKKSIKVLTYIDNTDL-IIAIDDDGKGIPETEYQQIFRPFYRVDEARDRQTGGTGLGLAIVANAVQQHKGSVQAMK 449
33152530  369 AQKYAKQSITVLIYIDDKEL-VMSVDDDGEGVPESEYKQIFRPFYRVGEARDRQSGGTGLGLAIVANAAQQHKGRVEAMK 447
15603753  371 ALKYTQSEIRVSIFLKRQEL-MIVIDDNGHGLDEAEYEKIFQPFYRVDETRTRETGGTGLGLAIVANVVKEHHGAVWANA 449
152995591 366 AIHYGKKQIQVSLEAHSDTL-SIRVEDDGDGVPEDEFDSIFRPFYRVSTARDRHSGGAGLGLAIAENAVRQHNGMIRAAR 444
251793483 366 ALKYTKSAIVMYIYIYENDL-FIRIEDNGEGLPQEEYEKIFKPFYRVDEARTRKTGGAGLGLSIVANTAKDHHGAVWARK 444
261867363 366 ALKYTKSAISVHIYTHENDL-FIRIEDNGAGLPEDEYEKIFKPFYRVDETRTRETGGTGLGLSIVANTAKDHHGAVWAGK 444
152978458 456 SPFGGLRIVMELPLVTDK 473
37681298  445 SDLGGLRVTITLPLVKRR 462
27364654  445 SDLGGLRVTITLPLVKRR 462
190149942 450 SPLGGLRIEIKLPLWIE- 466
165976043 450 SPLGGLRIEIKLPLWIE- 466
33152530  448 SILGGLRVETRLPLWLE- 464
15603753  450 SQLGGLCVTLCIPLWITS 467
152995591 445 SALGGLLVEVTLPLQEER 462
251793483 445 SGLGGLAVTLRLPLWIAK 462
261867363 445 ADLGGLAVILRLPLWVAK 462
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