1G7V,1FXQ,1G7U


Conserved Protein Domain Family
KdsA

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COG2877: KdsA (this model, PSSM-Id:225432 is obsolete and has been replaced by 442124)
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3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell wall/membrane/envelope biogenesis]
linked to 3D-structure
Statistics
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PSSM-Id: 225432
Aligned: 27 rows
Threshold Bit Score: 426.719
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1G7V_A     1 MKqKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQ--KLGIPYVFKASFDKANRSSIHSYRGPGLEEGM 78  Escherichia coli
6647568    1 ------------MFN-NKMILIAGPCVIEGEDITLEIAGKLQSILApySDRIQWFFKSSYDKANRSSLNSFRGPGLTEGL 67  Chlamydophila pneum...
7404395    1 ------------MFPENKMLLIAGPCVIE-DNSVFETARRLKEIVApyASSVHWIFKSSYDKANRSSVHNYRGPGLKLGL 67  Chlamydia trachomatis
20532146   1 -------------MK--KMILIAGPCVIESKDLIFKVAEQLKNFNE--NPNIEFYFKSSFDKANRTSINSFRGPGLEEGL 63  Campylobacter jejuni
22095791  12 NDvNKVKVGNIVFGGKKRFVLIAGPCVMESQELMDEVAGGIKEICD--RLGIEYIFKASFDKANRSSIYSYRGPGLEEGM 89  Fusobacterium nucle...
2498499    1 --------mkTSKTKTPKSVLIAGPCVIESLENLRSIATKLQPLAN--NERLDFYFKASFDKANRTSLESYRGPGLEKGL 70  Helicobacter pylori
20532118   1 -MqKVVKLNNIKIGNDLPFVLITGPCQIEGKDHALFMAEKLVKLTS--KLEIPFIYKSSFDKANRTSVHGIRGVGIEKGL 77  Rickettsia conorii
6647572    1 -MkKVVKLNNIKIGNDLQFVLIAGPCQIEGKDHALFMAEKLMKLTS--KLSIPFIYKSSFDKANRTSINGIRGLGIEKGL 77  Rickettsia prowazekii
15837890  15 QSgDVMKLCGFEVGLNQPLFLIAGPCVIESLQLQLDTAGVLKEITS--KLGLNFIFKSSFDKANRTSGSSFRGPGLEEGL 92  Xylella fastidiosa ...
7387815    1 --------mkTSNTKTPKPVLIAGPCVIESLENLRSIAIKLQPLAN--NERLDFYFKASFDKANRTSLESYRGPGLEKGL 70  Helicobacter pylori...
1G7V_A    79 KIFQELKQTFGVKIITDVHEPSQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFKEG 158 Escherichia coli
6647568   68 RILAKVKETFGVGILTDVHTPQDAYAAAEVCNILQVPAFLCRQTDLLVATAETGAIVNLKKGQFLSPWDMEGPINKVLST 147 Chlamydophila pneum...
7404395   68 QTLAKIKEELDVEILTDVHSPDEAREAAKVCDIIQVPAFLCRQTDLLVTAGETQAIVNIKKGQFLSPWEMQGPIDKVLST 147 Chlamydia trachomatis
20532146  64 KILQSVKDEFGMKILTDIHESNQANPVSEVADVLQIPAFLCRQTDLLVAAAKTKAKINIKKGQFLNPSDIKYSVKKVLQT 143 Campylobacter jejuni
22095791  90 KMLTKIKEKFNVPVITDVHEAWQCKEVAKVADILQIPAFLCRQTDLLIAAAETGKAVNIKKGQFLAPWDMKNIVVKMEES 169 Fusobacterium nucle...
2498499   71 EMLQTIKEEFGYKILTDVHESYQASVAAKVADILQIPAFLCRQTDLIVEVSQTNAIVNIKKGQFMNPKDMQYSVLKALKT 150 Helicobacter pylori
20532118  78 EILSKVKSEFDCPIVTDVHSESQCTETAEVADILQIPAFLCRQTDLLQAAAKTGKIVKVKKGQFLAPWDMKNVQTKLEAF 157 Rickettsia conorii
6647572   78 EILSKVKSEFDCPIITDVHSESQCIETAKVVDILQIPAFLCRQTDLLKAAAKTGKIVKVKKGQFLAPWDMKNVQKKLEVF 157 Rickettsia prowazekii
15837890  93 KVLEAVKTQIGVPVLTDVHEYTPIDEVATVVDVLQTPAFLVRQTDFIRNVCAVGKPVNIKKGQFLSPWDMKPVVEKAKST 172 Xylella fastidiosa ...
7387815   71 EMLQTIKDEFGYKILTDVHESYQASVAAKVADILQIPAFLCRQTDLIVEVSQTNAIVNIKKGQFMNPKDMQYSVLKALKT 150 Helicobacter pylori...
1G7V_A   159 G-------------NEKVILCDRGANFGYDNLVVDMLGFSIMKKVSgnSPVIFDVTHALQCRDPFGAASGGRRAQVAELA 225 Escherichia coli
6647568  148 G-------------NNKILLTERGCSFGYNNLVSDMRSIPVLSRSG--FPVIFDATHSVQLPGALSTESGGLTEFVPTLS 212 Chlamydophila pneum...
7404395  148 G-------------NNKIILTERGCSFGYNNLVSDMRSIEVLRRFG--FPVVFDGTHSVQLPGALHSQSGGQTEFIPVLT 212 Chlamydia trachomatis
20532146 144 Rgiedeg--yeaaqRNGVFVAERGASFGYGNLVVDMRSLVIMREF---APVIFDATHSVQMPGAAGGSSGGKSEFVEPLA 218 Campylobacter jejuni
22095791 170 R-------------NKNIMLCERGSTFGYNNMVVDMRSLLEMRKFN--YPVIFDVTHSVQKPGGLGTATSGDREYVYPLL 234 Fusobacterium nucle...
2498499  151 RdksiqsptyetalKNGVWLCERGSSFGYGNLVVDMRSLKIMREF---APVIFDATHSVQMPGGANGKSSGDSSFAPILA 227 Helicobacter pylori
20532118 158 G-------------VKDILFTERGACFGYNNLVSDMRSLAIMAELN--VPVVFDATHSVQQPGGLGGSTGGERKYVELLA 222 Rickettsia conorii
6647572  158 G-------------AKDILFTERGSCFGYNNLVSDMRSLAIMSELN--VPVVFDATHSVQQPGGRGGSSGGERKYVELLA 222 Rickettsia prowazekii
15837890 173 G-------------NSQILVCERGASFGYNNLVSDMRSLAVMRETG--CPVVFDATHSVQLPGAQGGRSGGQREFVPVLA 237 Xylella fastidiosa ...
7387815  151 RdssiqsptyetalKNGVWLCERGSSFGYGNLVVDMRSLKIMREF---APVIFDATHSVQMPGGANGKSSGDSSFPPILP 227 Helicobacter pylori...
1G7V_A   226 RAGMAVGLAGLFIEAHPDPEHAKCDGPSALPLAKLEPFLKQMKAIDDLVKGFEELDT 282 Escherichia coli
6647568  213 RAALAAGAHGLFIETHTNPKIAKSDAASMLSLEEFAALLPTWDQLFTCVSSFDMVSA 269 Chlamydophila pneumoniae
7404395  213 RSAIAAGVQGLFIETHPNPSSALSDAASMLSLKDLERLLPAWVQLFTYIQEMDAVSV 269 Chlamydia trachomatis
20532146 219 RAAAAVGIDGFFFETHINPCEALCDGPNMLNLTRLKNCVNTLLEIQNIIKENK---- 271 Campylobacter jejuni
22095791 235 RAGLAIGVDAIFAEVHPNPAEAKSDGPNMLYLKDLEEILKIAIEIDKIVKGV----- 286 Fusobacterium nucleatum subsp. nucleatum
2498499  228 RAAAAVGIDGLFAETHVDPKNALSDGANMLKPDELEQLVTDMLKIQNLF-------- 276 Helicobacter pylori
20532118 223 KAATSVGIAGIYMEVHQDPDNAPSDGPCMMKLDNLESILIKLKKYDKITKEK----- 274 Rickettsia conorii
6647572  223 KAAISVGIAGIYMEVHQDPDNAPSDGPCMIKLDNLESILIKLKKYDKITKEIV---- 275 Rickettsia prowazekii
15837890 238 RAAVAVGISGLFAETHPDPPNALSDGPNAWPLHTMAMLLETLVELDAVTKKRGFLEQ 294 Xylella fastidiosa 9a5c
7387815  228 RAAAAVGIDGLFAETHIDPKNALSDGANMLKPDELEHLVTDMLKIQNLF-------- 276 Helicobacter pylori J99
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