3W9I,1OY6,4MT1


Conserved Protein Domain Family
2A0602
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TIGR00915: 2A0602 
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The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family
Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Links
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Statistics
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PSSM-Id: 273335
Aligned: 12 rows
Threshold Bit Score: 1570.88
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3W9I_A          1 MSKFFIDRPIFAWVIALVIMLAGGLSILSLPVNQYPAIAPPAIAVQVSYPGASAETVQDTVVQVIEQQMNGIDNLRYISS 80   Pseudomonas a...
P24181          1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQVIEQNMNGIDNLMYMSS 80   Escherichia c...
AAA74437        1 MSKFFIDRPIFAWVIALVIMLAGGLSILSLPVNQYPAIAPPAIAVQVSYPGASAETVQDTVVQVIEQQMNGIDNLRYISS 80   Pseudomonas a...
AAC38671        1 MSKFFIDRPIFAWVIALVIMLVGALSILKLPINQYPSIAPPAIAIAVTYPGASAQTVQDTVVQVIEQQLNGIDNLRYVSS 80   Pseudomonas p...
P24177          1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRVTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS 80   Escherichia c...
AAD12176        1 MSRFFIDRPIFAWVLAIVAMLAGALSLAKMPISQYPNIAAPAVSIQVSYPGASAQTVQDTVVQVIEQQLSGLDGFRYMSA 80   Pseudomonas p...
AAC25691        1 MARFFIDRPIFAWVIAIIIMGLGVLSIMRLPISQYPSIAGPSVVIGATYPGASAETVADTVVQIIEKEMTGLDGLRYIDS 80   Agrobacterium...
AAC45560        1 MAKFFIDRPIFAWVISIFIIAAGIFGIKSLPVSQYPSVAAPTITLHAIYPGASAQVMEGSVLSVIERNMNGVEGLDYMST 80   Neisseria gon...
WP_010872694    2 FVDFFIKRPVFSSVCAIIILLVGTISIFSLPIAQFPEVAPTTIQVSSNYSGANAEVVERAVTDILERQINGVQGMRYISS 81   Synechocystis...
P31224          1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80   Escherichia c...
1OY6_A          1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80   Escherichia c...
4MT1_A          1 MAKFFIDRPIFAWVISIFIIAAGIFGIKSLPVSQYPSVAAPTITLHAIYPGASAQVMEGSVLSVIERNMNGVEGLDYMST 80   Neisseria gon...

3W9I_A         81 ESNSDGSMTITVTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGIRVTKAVKNFLMVVGVVSTDGSMTKEDLSNYIVS 160  Pseudomonas a...
P24181         81 TSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVAS 160  Escherichia c...
AAA74437       81 ESNSDGSMTTTVTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGIRVTKAVKNFLMVVGVVSTDGSMTKEDLSNYIVS 160  Pseudomonas a...
AAC38671       81 ESNSDGSMTITATFEQGTNPDTAQVQVQNKLNLATPLLPQEVQQQGIRVTKAVKNFLLVIGLVSEDGSMTKDDLANYIVS 160  Pseudomonas p...
P24177         81 QSSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS 160  Escherichia c...
AAD12176       81 ESASDGSMTIIVTFEQGTDPDIAQVQVQNKLQLATPRLPEEVQRQGLRVVKYQMNFFLVMSLVDRSGKLDNFDLGNLIAS 160  Pseudomonas p...
AAC25691       81 STTSTGRATVTLTFNLGTDPDIAQVQVQNKLSQAEASLPSEVTRQGVTVEKSTTGFLMVIALISDDGARSAIDLADYLNS 160  Agrobacterium...
AAC45560       81 SADSSGSGSVSLTFTPDTDENLAQVEVQNKLSEVLRTLPATVQQYGVTVSKARSNFLMIVMLSSD--VQSTEEMNDYAQR 158  Neisseria gon...
WP_010872694   82 TSSNDGTSSITVTFDRSQNKDIAAVDVQNRVALAEPQLPEAVRRTGIRVNKESNALLLGIGITSPDGEYDNVFLSNYADR 161  Synechocystis...
P31224         81 NSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA 160  Escherichia c...
1OY6_A         81 NSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA 160  Escherichia c...
4MT1_A         81 SADSSGSGSVSLTFTPDTDENLAQVEVQNKLSEVLSTLPATVQQYGVTVSKARSNFLMIVMLSSD--VQSTEEMNDYAQR 158  Neisseria gon...

3W9I_A        161 NIQDPLSRTKGVGDFQVFGS-QYSMRIWLDPAKLNSYQLTPGDVSSAIQAQNVQISSGQLGGLPAVKGQQLNATIIGKTR 239  Pseudomonas a...
P24181        161 NVKDTLSRLNGVGDVQLFGA-QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239  Escherichia c...
AAA74437      161 NIQDPLSRTKGVGDFQVFGS-QYSMRIWLDPAKLNSYQLTPGDVSSAIQAQNVQISSGQLGGLPAVKGQQLNATIIGKTR 239  Pseudomonas a...
AAC38671      161 NMQDPISRTAGVGDFQVFGA-QYAMRIWLDPAKLNKFQLTPVDVKTAVAAQNVQVSSGQLGGLPALPGTQLNATIIGKTR 239  Pseudomonas p...
P24177        161 NIQDPLSRVNGVGDIDAYGS-QYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSL 239  Escherichia c...
AAD12176      161 QLQDPISRIPGVGDFQLFGS-PYAMRIWLDPGKLNSYQLTPTDVASAIREQNVQVSSGQLGGLPTRSGVQLNATVLGKTR 239  Pseudomonas p...
AAC25691      161 YMVEPVSRLKGVGKVEVFGS-EYAMRIWLDPQKLKYYGLSPTTVIHAISAQNAQISAGSFGAMPAPEGQQLNATVTAQSL 239  Agrobacterium...
AAC45560      159 NVVPELQRIEGVGQVRLFGA-QRAMRIWVDPKKLQNYNLSFADVGSALSAQNIQISAGSIGSLPAVRGQTVTATVTAQGQ 237  Neisseria gon...
WP_010872694  162 YLVDPIRRLEGVGDVRIFGErLYAMRLWVDPMKLAAQQLTMADLSRALQEQNLQVGAGQIGAEPAPPGQEYQLDLLASSQ 241  Synechocystis...
P31224        161 NMKDAISRTSGVGDVQLFGS-QYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTR 239  Escherichia c...
1OY6_A        161 NMKDAISRTSGVGDVQLFGS-QYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTR 239  Escherichia c...
4MT1_A        159 NVVPELQRIEGVGQVRLFGA-QRAMRIWVDPKKLQNYNLSFADVGSALSAQNIQISAGSIGSLPAVRGQTVTATVTAQGQ 237  Neisseria gon...

3W9I_A        240 LQTAEQFENILLKVNPDGSQVRLKDVADVGLGGQDYSINAQFNGSPASGIAIKLATGANALDTAKAIRQTIANLEPFMPQ 319  Pseudomonas a...
P24181        240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQ 319  Escherichia c...
AAA74437      240 LQTAEQFENILLKVNPDGSQVRLKDVADVGLGGQDYSINAQFNGSPASGIAIKLATGANALDTAKAIRQTIANLEPFMPQ 319  Pseudomonas a...
AAC38671      240 LQTAEQFESILLKVNKDGSQVRLGDVAQVGLGGENYAVSAQFNGKPASGLAVKLATGANALDTAKALRETIKGLEPFFPP 319  Pseudomonas p...
P24177        240 LQTPEQFRDITLRVNQDGSEVRLGDVATVEMGAEKYDYLSRFNGKPASGLGVKLASGANEMATAELVLNRLDELAQYFPH 319  Escherichia c...
AAD12176      240 MTTPSQFDEILVKVNPDGSQVRVKDVGRAELGADSFAISAQYKDSPTASLALRLSTGGNLLETVDAVKKLMEQQKAYLPD 319  Pseudomonas p...
AAC25691      240 LKTPQDFERIVLRADTDGGLVLLRDVARAELGTENYEISSFYNGKPSSGVAIQLASGANALETAELVKAKMADLGAFLPA 319  Agrobacterium...
AAC45560      238 LGTAEEFGNVILRANTDGSNIYLKDVAKVGLGMEDYSSSTRLNGVNTTGMAVMLSNSGNAMATAKAVKERLAVLEKYFPQ 317  Neisseria gon...
WP_010872694  242 LVEVKDFEDLIVKSGASGSVVRFKDIGRVELGAQNYNSFLRFRGDEAVGLGIYQLLDSNALEVARLVKDEMARLAQNFPE 321  Synechocystis...
P31224        240 LTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPS 319  Escherichia c...
1OY6_A        240 LTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPS 319  Escherichia c...
4MT1_A        238 LGTAEEFGNVILRANTDGSNIYLKDVAKVGLGMEDYSSSTRLNGVNTTGMAVMLSNSGNAMATAKAVKERLAVLEKYFPQ 317  Neisseria gon...

3W9I_A        320 GMKVVYPYDTTPVVSASIHEVVKTLGEAILLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFGVLAAFGFSINTLTMFGMV 399  Pseudomonas a...
P24181        320 GMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMV 399  Escherichia c...
AAA74437      320 GMKVVYPYDTTPVVSASIHEVVKTLGEAILLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFGVLAAFGFSINTLTMFGMV 399  Pseudomonas a...
AAC38671      320 GVKAVFPYDTTPVVTESISGVIHTLIEAVVLVFLVMYLFLQNFRATIITTMTVPVVLLGTFGILAAAGFSINTLTMFAMV 399  Pseudomonas p...
P24177        320 GLEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNTLTMFAMV 399  Escherichia c...
AAD12176      320 GVEVIYPYDTTPVVEASIESVVHTIFEAVVLVFLVMYLFLQSFRATLIPTLAVPVVLLATFALLPYFGLNINVLTMYAMV 399  Pseudomonas p...
AAC25691      320 GVSYVIPYDTTPFVSLSIEAVIHTLIEAIVLVVFVMLIFLHNFRATLIPTLAVPVVLLGTFGIMAALGFSINTLTMLAMV 399  Agrobacterium...
AAC45560      318 GMSWKTPYDTSKFVEISIEKVIHTLIEAMVLVFVVMYLFLQNIRYTLIPTIVVPISLLGGFAFISYMGMSINVLTMFAMI 397  Neisseria gon...
WP_010872694  322 GIEYSVAFDTTEFVQESLSEVVETLLIAVVLVILVILVFLQDWRSALIPALTIPLALIGTFAFVKVFNFSINSLTLFGLT 401  Synechocystis...
P31224        320 GLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMV 399  Escherichia c...
1OY6_A        320 GLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMV 399  Escherichia c...
4MT1_A        318 GMSWKTPYDTSKFVEISIEKVIHTLIEAMVLVFVVMYLFLQNIRYTLIPTIVVPISLLGGFAFISYMGMSINVLTMFAMI 397  Neisseria gon...

3W9I_A        400 LAIGLLVDDAIVVVENVERVMAEEGLSPREAARKSMGQIQGALVGIAMVLSAVFLPMAFFGGSTGVIYRQFSITIVSAMA 479  Pseudomonas a...
P24181        400 LAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479  Escherichia c...
AAA74437      400 LAIGLLVDDAIVVVENVERVMAEEGLSPREAARKSMGQIQGALVGIAMVLSAVFLPMAFFGGSTGVIYRQFSITIVSAMA 479  Pseudomonas a...
AAC38671      400 LAIGLLVDDAIVVVENVERVMSEEGLPPKEATKRSMEQIQGALVGIALVLSAVLLPMAFFGGSTGVIYRQFSITIVSAMG 479  Pseudomonas p...
P24177        400 LAIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVAAMV 479  Escherichia c...
AAD12176      400 LAIGLLVDDAIVVVENVERLMHDEGLSPLEATRKSMDQISGALVGIGMVLSAVFVPMAFFGGSAGIIYQQFAITIVVCMG 479  Pseudomonas p...
AAC25691      400 LAIGLLVDDAIVVVENVERIMRDEHLDPVAATKNRWEKSRARSWASPWWFPPSSCRWRFSAVQQGEMYKQFSVTIVAAMA 479  Agrobacterium...
AAC45560      398 LVIGIVVDDAIVVVENVERIMAGEGLPPKEATKKAMGQISGAVIGITAVLISVFVPLAMFSGAAGNIYKQFALTMASSIA 477  Neisseria gon...
WP_010872694  402 LATGLVVDDAIIVVEQISRFIKVKHEDPQEAAQEAMGELTGAVIATSLVLMAVFIPVAFFPGTTGALYQQFALTIAFSIL 481  Synechocystis...
P31224        400 LAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMA 479  Escherichia c...
1OY6_A        400 LAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMA 479  Escherichia c...
4MT1_A        398 LVIGIVVDDAIVVVENVERIMAGEGLPPKEATKKAMGQISGAVIGITAVLISVFVPLAMFSGAAGNIYKQFALTMASSIA 477  Neisseria gon...

3W9I_A        480 LSVIVALILTPALCATMLKPIEkGDHGEHKGGFFGWFNRMFLSTTHGYERGVASILKHRAPYLLIYVVIVAGMIWMFTRI 559  Pseudomonas a...
P24181        480 LSVLVALILTPALCATLLKPVS-AEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRL 558  Escherichia c...
AAA74437      480 LSVIVALILTPALCATMLKPIEkGDHGEHKGGFFGWFNRMFLSTTHGYERGVASILKHRAPYLLIYVVIVAGMIWMFTRI 559  Pseudomonas a...
AAC38671      480 LSVLVALIFTPALCATMLKPLKkGEHHTAKGGFFGWFNRNFDRSVNGYERSVGTILRNKVPFLLAYALIVVGMIWLFARI 559  Pseudomonas p...
P24177        480 LSVLVAMILTPALCATLLKPLKkGEHHGQK-GFFAWFNQMFNRNAERYEKGVAKILHRSLRWIVIYVLLLGGMVFLFLRL 558  Escherichia c...
AAD12176      480 LSILVALVFTPALCVTILKAPEgNSHHERKG-FFGWFNRIFDRGTRRFERGVGAMLKGRGRYLLAFLLITGGTGYLFTQI 558  Pseudomonas p...
AAC25691      480 LSVLVALIFTPALCATMLKAHDhNAKSGLASRFSNWFERNFSWLTTRYGNVVRASAKRPLRMFLVYLLLVGAMVFLYQKT 559  Agrobacterium...
AAC45560      478 FSAFLALTLTPALCATMLKTIPkGHHEEKK-GFFGWFNKKFDSWTHGYEGRVAKVLRKTFRMMVVYIGLAVVGVFLFMRL 556  Neisseria gon...
WP_010872694  482 LSTFLALTLTPSLCALLLREGQ--EPPAFIAGFFNWFNRVLDIIKNGYGNVLGKLVNLRAWVIGVFVLLLGATAWLYVTV 559  Synechocystis...
P31224        480 LSVLVALILTPALCATMLKPIAkGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRL 559  Escherichia c...
1OY6_A        480 LSVLVALILTPALCATMLKPIAkGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRL 559  Escherichia c...
4MT1_A        478 FSAFLALTLTPALCATMLKTIPkGHHEEKK-GFFGWFNKKFDSWTHGYEGRVAKVLRKTFRMMVVYIGLAVVGVFLFMRL 556  Neisseria gon...

3W9I_A        560 PTAFLPDEDQGVLFAQVQTPPGSSAERTQVVVDSMREYLLEKESSSVSSVFTVTGFNFAGRGQSSGMAFIMLKPWEERPG 639  Pseudomonas a...
P24181        559 PSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNG 638  Escherichia c...
AAA74437      560 PTAFLPDEDQGVLFAQVQTPPGSSAERTQVVVDSMREYLLEKESSSVSSVFTVTGFNFAGRGQSSGMAFIMLKPWEERPG 639  Pseudomonas a...
AAC38671      560 PTAFLPEEDQGVLFAQVQTPAGSSAERTQVVVDQMREYLLKDEADTVSSVFTVNGFNFAGRGQSSGMAFIMLKPWDERSK 639  Pseudomonas p...
P24177        559 PTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEQIEKYYFTHEKDNIMSVFATVGSGPGGNGQNVARMFIRLKDWSERDS 638  Escherichia c...
AAD12176      559 PKAFLPNEDQGLMMIEVRTPANASAERTEGVLQEVRDYLANDEGALVEHFMTVNGFNFAGRGQNSGLVLITFKDWKERHG 638  Pseudomonas p...
AAC25691      560 PTSFLPDEDQGTLMTIIQTPPGSTAQNTEAVLGKVENYYMNAEAQNVESVFSVSWFLLAGQGQNMGMMFVKLKDWEERKG 639  Agrobacterium...
AAC45560      557 PTSFLPTEDQGFVMVSVQLPAGATKERTDATLAQVTQ--LAKSIPEIENIITVSGFSFSGSGQNMAMGFAIFKDWNERTA 634  Neisseria gon...
WP_010872694  560 PTAFLPEEDQGYFITIIQAPQGVSLQYTSRVMAQVEKELLAVP--EVTATFAVGGFSFSGNSPNQGIIFTRLKPWGERTA 637  Synechocystis...
P31224        560 PSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPG 639  Escherichia c...
1OY6_A        560 PSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPG 639  Escherichia c...
4MT1_A        557 PTSFLPTEDQGFVMVSVQLPAGATKERTDATLAQVTQ--LAKSIPEIENIITVSGFSFSGSGQNMAMGFAIFKDWNERTA 634  Neisseria gon...

3W9I_A        640 GENSVFELAKRAQMHFF-SFKDAMVFAFAPPSVLELGNATGFDLFLQD-QAGVGHEVLLQARNKFLMLAAQNP--A--LQ 713  Pseudomonas a...
P24181        639 DENSAEAVIHRAKMELG-KIRDGFVIPFNMPAIVELGTATGFDFELID-QAGLGHDALTQARNQLLGMAAQHP--As-LV 713  Escherichia c...
AAA74437      640 GENSVFELAKRAQMHFF-SFKDAMVFAFAPPSVLELGNATGFDLFLQD-QAGVGHEVLLQARNKFLMLAAQNP--A--LQ 713  Pseudomonas a...
AAC38671      640 -ENSVFALAQRAQQHFF-TFRDAMVFAFAPPAVLELGNATGFDVFLQD-RGGVGHAKLMEARNQFLAKAAQSK--I--LS 712  Pseudomonas p...
P24177        639 KTGTSFAIIERATKAFN-QIKEARVIASSPPAISGLGSSAGFDMELQD-HAGAGHDALMAARNQLLALAAENP--E--LT 712  Escherichia c...
AAD12176      639 AGQDVFSIAQRANQHFA-KIKDASVMAFVPPAILEMGNAMGFNLYLQD-NLGLGHEALMAARNQFLQLASQNP--K--LQ 712  Pseudomonas p...
AAC25691      640 KENSAQAIAARAFGPLMgGIKEAIVVPLVPPAVTELGNSNGFTAFLQA-RSGQSHEQLLEARNMLLGLAAQSP--K--LM 714  Agrobacterium...
AAC45560      635 SGSDAVAVAGKLTGMMMgTLKDGFGIAVVPPPILELGNGSGLSINLQD-RNNTGHTGIAGEGNELIQKMRASG--LfdPS 711  Neisseria gon...
WP_010872694  638 PNQSVQAIIGQMFGKFS-QIPEANIIPINPPPIRGLGQFGGFDFQLQDlRVNSELDTMVGTMGEILGAANQNP--A--LT 712  Synechocystis...
P31224        640 EENKVEAITMRATRAFS-QIKDAMVFAFNLPAIVELGTATGFDFELID-QAGLGHEKLTQARNQLLAEAAKHP--Dm-LT 714  Escherichia c...
1OY6_A        640 EENKVEAITMRATRAFS-QIKDAMVFAFNLPAIVELGTATGFDFELID-QAGLGHEKLTQARNQLLAEAAKHP--Dm-LT 714  Escherichia c...
4MT1_A        635 SGSDAVAVAGKLTGMMMgTLKDGFGIAVVPPPILELGNGSGLSINLQD-RNNTGHTALLAKRNELIQKMRASGlfD--PS 711  Neisseria gon...

3W9I_A        714 RVRPNGMSDEPQYKLEIDDEKASALGVSLADINSTVSIAWGSSYVNDFIDRGRVKRVYLQGRPDARMNPDDLSKWYVRND 793  Pseudomonas a...
P24181        714 SVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSA 793  Escherichia c...
AAA74437      714 RVRPNGMSDEPQYKLEIDDEKASALGVSLADINSTVSIAWGSSYVNDFIDRGRVKRVYLQGRPDARMNPDDLSKWYVRND 793  Pseudomonas a...
AAC38671      713 AVRPNGLNDEPQYQLTIDDERASALGVTIADINNTLSIALGASYVNDFIDRGRVKKVYIQGEPSARMSPEDLQKWYVRNG 792  Pseudomonas p...
P24177        713 RVRHNGLDDSPQLQIDIDQRKAQALGVAIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNK 792  Escherichia c...
AAD12176      713 AVRPNGKDDEPQFQVNIDDEKARALQVSIASINETMSAAWGSMYVNDFIDRGRVKRVYVQGEDISRISPEDFDKWYVRNS 792  Pseudomonas p...
AAC25691      715 AVRPNGVEDASQFELNIDWGKAGAVGLSAADVGSFLTTVWSSSYVNDFLYEGRMKRVYVQGEPLARTGPEDLALWRVPNA 794  Agrobacterium...
AAC45560      712 TVRAGGLEDSPQLKIDINRAAAAAQGISFADIRTALASALSSSYVSDFPNQGRLQRVMVQADEDARMQPADILNLTVPNK 791  Neisseria gon...
WP_010872694  713 RVFSTFQANNPQLIVNVNRNKAKSLGVPVDQIFQTMETALGSSYVNDFVLQGRTYRVYLQADEQFRSSPEDINSLYVRSE 792  Synechocystis...
P31224        715 SVRPNGLEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAA 794  Escherichia c...
1OY6_A        715 SVRPNGLEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAA 794  Escherichia c...
4MT1_A        712 TVRAGGLEDSPQLKIDINRAAAAAQGISFADIRTALASALSSSYVSDFPNQGRLQRVMVQADEDARMQPADILNLTVPNK 791  Neisseria gon...

3W9I_A        794 KGEMVPFNAFATGKWEYGSPKLERYNGVPAMEILGEPAPGLSSGDAMAAVEEIV-KQLPKGVGYSWTGLSYEERLSGSQA 872  Pseudomonas a...
P24181        794 NGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLA-SKLPAGIGYDWTGMSYQERLSGNQA 872  Escherichia c...
AAA74437      794 KGEMVPFNAFATGKWEYGSPKLERYNGVPAMEILGEPAPGLSSGDAMAAVEEIV-KQLPKGVGYSWTGLSYEERLSGSQA 872  Pseudomonas a...
AAC38671      793 AGEMVPFSSFAKGEWTYGSPKLSRYNGVEAMEILGAPAPGYSTGEAMAEVERIA-GELPSGIGFSWTGMSYEEKLSGSQM 871  Pseudomonas p...
P24177        793 DGGMVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLV-KQLPNGFGLEWTAMSYQERLSGAQA 871  Escherichia c...
AAD12176      793 LGQMVPFSAFATGEWVNGSPKLERYGGISSLNILGEPAPGYSTGDAMIAIAEIM-QQLPAGIGLSYTGLSYEEIQTGDQA 871  Pseudomonas p...
AAC25691      795 NGDFVDLSTIASQNWVFGPQQVIRYDALPAMSIEGSAAPGFSSGEALAEIEALA-AKLPPGFSLQWTGMSLEEKDAGAGA 873  Agrobacterium...
AAC45560      792 SGVAVPLSTIATVSWENGTEQSVRFNGYPSMKLSASPATGVSTGQAMEAVQKMV-DELGGGYSFEWGGQSSEEAKGGSQT 870  Neisseria gon...
WP_010872694  793 SGTMIPMANLVTVTQGVGAPIITHYNLFRSIAITGSANFGVSTGQAMNAMAAIArQVMPPGFDFQWSGISLEEMGSQGQA 872  Synechocystis...
P31224        795 DGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLA-SKLPTGVGYDWTGMSYQERLSGNQA 873  Escherichia c...
1OY6_A        795 DGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLA-SKLPTGVGYDWTGMSYQERLSGNQA 873  Escherichia c...
4MT1_A        792 SGVAVPLSTIATVSWENGTEQSVRFNGYPSMKLSASPATGVSTGQAMEAVQKMV-DELGGGYSFEWGGQSSEEAKGGSQT 870  Neisseria gon...

3W9I_A        873 PALYALSLLVVFLCLAALYESWSIPFSVMLVVPLGVIGALLATSMR-----------G-----------LSNDVFFQVGL 930  Pseudomonas a...
P24181        873 PALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLF-----------N-----------QKNDVYFMVGL 930  Escherichia c...
AAA74437      873 PALYALSLLVVFLCLAALYESWSIPFSVMLVVPLGVIGALLATSMR-----------G-----------LSNDVFFQVGL 930  Pseudomonas a...
AAC38671      872 PALFALSVLFVFLCLAALYESWSIPIAVVLVVPLGIIGALIATSLR-----------G-----------LSNDVYFLVGL 929  Pseudomonas p...
P24177        872 PALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMR-----------G-----------LENDVYFQVGL 929  Escherichia c...
AAD12176      872 PLLYALTVLIVFLCLAALYESWSVPVSVIMVVPLGILGAVLATLWR-----------D-----------LTADVYFQVGL 929  Pseudomonas p...
AAC25691      874 LPLYGLALATMFLCLAALYESWTIPVAVLLAMPVGILGALLGAWIG-----------G-----------QSNGVYFQVGL 931  Agrobacterium...
AAC45560      871 LILYGLAVAAVFLVLAALYESWSIPLAVILVIPLGLIGAAAGVTGRnlfegllgsvpS-----------FANDIYFQVGF 939  Neisseria gon...
WP_010872694  873 PLIFGLGLLFVFLVLAAQYENYIDPVIILLSVPLAILGALTAQSLR-----------G-----------FPNDVYCQIGL 930  Synechocystis...
P31224        874 PSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFR-----------G-----------LTNDVYFQVGL 931  Escherichia c...
1OY6_A        874 PSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFR-----------G-----------LTNDVYFQVGL 931  Escherichia c...
4MT1_A        871 LILYGLAVAAVFLVLAALYESWSIPLAVILVIPLGLIGAAAGVTGR-----------NlfegllgsvpsFANDIYFQVGF 939  Neisseria gon...

3W9I_A        931 LTTIGLSAKNAILIVEFAKELHEQ-GKGIVEAAIEACRMRLRPIVMTSLAFILGVVPLAISTGAGSGSQHAIGTGVIGGM 1009 Pseudomonas a...
P24181        931 LTTIGLSAKNAILIVEFAKDLMEKeGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGM 1010 Escherichia c...
AAA74437      931 LTTIGLSAKNAILIVEFAKELHEq-GKGIVEAAIEACRMRLRPIVMTSLAFILGVVPLAISTGAGSGSQHAIGTGVIGGM 1009 Pseudomonas a...
AAC38671      930 LTTIGLAAKNAILIVEFAKELHEq-GRSLYDAAIEACRMRLRPIIMTSLAFILGVVPLTIASGAGAGSQHAIGTGVIGGM 1008 Pseudomonas p...
P24177        930 LTVIGLSAKNAILIVEFANEMNQK-GHDLFEATLHACRQRLRPILMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGM 1008 Escherichia c...
AAD12176      930 MTTVGLSAKNAILIVEFAKELYEKeGYPIVKAAIEAAKLRLRPILMTSLAFTFGVLPMAIASGAGAGSQHSIATGVVGGM 1009 Pseudomonas p...
AAC25691      932 LTVVGLTGKNGIMIVEFARERMAQlGESAFEAVCQAAKLRFRPILMTSLAFGLGVIPLVISTGAGAGARQAIGYATFFGT 1011 Agrobacterium...
AAC45560      940 VTVMGLSAKNAILIIEFAKDLQAQ-GKSAVEAALEAARLRFRPIIMTSFAFILGVVPLYIAAGASSASQRAIGTTVFWGM 1018 Neisseria gon...
WP_010872694  931 VMLIGLSSKNAILIVEFANQLRAe-GYPIAKAALEASKDRLRPILMTALSTLFGIFPLAIATGAGAGSRQALGTAVFGGM 1009 Synechocystis...
P31224        932 LTTIGLSAKNAILIVEFAKDLMDKeGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGM 1011 Escherichia c...
1OY6_A        932 LTTIGLSAKNAILIVEFAKDLMDKeGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGM 1011 Escherichia c...
4MT1_A        940 VTVMGLSAKNAILIIEFAKDLQAQ-GKSAVEAALEAARLRFRPIIMTSFAFILGVVPLYIAAGASSASQRAIGTTVFWGM 1018 Neisseria gon...

3W9I_A       1010 VTATVLAIFWVPLFYVAVS----TLFKD 1033 Pseudomonas aeruginosa PAO1
P24181       1011 VSATLLAIFFVPVFFVVIR----RCFKG 1034 Escherichia coli K-12
AAA74437     1010 VTATVLAIFWVPLFYVAVS----TLFKD 1033 Pseudomonas aeruginosa
AAC38671     1009 ISATVLAIFWVPLFFVAVS----SLFGS 1032 Pseudomonas putida
P24177       1009 ISATILAIYFVPLFFVLVR----RRFPL 1032 Escherichia coli K-12
AAD12176     1010 ITATVLAVFFVPLFYVVVV----KLFEG 1033 Pseudomonas putida
AAC25691     1012 VTGTLLAIVFVPVFFVLIS----GIFSR 1035 Agrobacterium tumefaciens
AAC45560     1019 LVGTLLSVFLVPLFYVVVR----KFFKE 1042 Neisseria gonorrhoeae
WP_010872694 1010 LVATFLSLFVVPVLYIVVKtisgRLLAP 1037 Synechocystis sp. PCC 6803
P31224       1012 VTATVLAIFFVPVFFVVVR----RRFSR 1035 Escherichia coli K-12
1OY6_A       1012 VTATVLAIFFVPVFFVVVR----RRFSR 1035 Escherichia coli K-12
4MT1_A       1019 LVGTLLSVFLVPLFYVVVR----KFFKE 1042 Neisseria gonorrhoeae PID332
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