Conserved Protein Domain Family
FtsX_Gpos

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NF038347: FtsX_Gpos 
permease-like cell division protein FtsX
The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages.
Statistics
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PSSM-Id: 468488
Aligned: 219 rows
Threshold Bit Score: -1
Created: 24-Apr-2023
Updated: 3-May-2023
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_003078621   2 IrRFFRHLWQSIKNLKRNGWMTVAAVTSVTITLILAGIFAAFLLNTEKLASGVEKNVQINTYLQVDSKDNMESyvdtndn 81  Streptococcus m...
WP_009274055   5 IqSLPKHFMTALRNLARHMAMTLSSASAVAVTLTLMTLFLVLAANMNSFANNVETNLKIHASIDS-LQKENEIq------ 77  [Clostridium] i...
WP_008978183   5 VkYLPKHVLSALKGLQRHMAMTISSVSAVSVTLLLMALFFVIAGNVENFTQHVEGDLKIHVAIDS-IADQDAIt------ 77  Longicatena cae...
WP_004798178   5 LkSLPKHFTTAVKNLVRHTAMSFSSASAVTVTLIMMACFMLLAGNISGFTSNVETDLKIRVEIDN-IVTEEGIa------ 77  Amedibacillus d...
WP_002608053   5 YrYIKFHLKMTYKNIVRHFGLTFSASVAVSITLILISVFMLLTSNLNCFTKHIEQQVTIRASIDT-IVKDKQKq------ 77  [Clostridium] i...
WP_003774428   1 MgRVWRHIKDGITGVTRHFALSLSSISSVTVTLLLMSIFLFLSVNISTITKSMEQSVQIHAQISNDFEEKSQIn------ 74  Erysipelothrix
WP_015536327   5 LnLALYELKYAFIGIKRHLLLCLSAISAITISLFLMAAFLVVGIHVDHFATNVQSDLSIHVILDQDIVEDDQIg------ 78  Faecalitalea cy...
WP_003865590   4 LrTFLYELKYAFLQMKRHIMLCFSAISAIGITLLLIGAVLIIGLHVNYFSNDVQKDLSIHVILNEDIKDEASMq------ 77  Holdemanella bi...
WP_016648831   4 VrSFFRHLRDAGRNFTRNGWMTTASVVMMSVTLFFLGLFFLVAANVEQLTHTVENEIQIRVTIDP-IANVEEQk------ 76  Facklamia hominis
WP_006308561   4 IrSFFRHQRDAYRYLFRNGWMTSASILMMTLTLFLTGLLMVFVGNVDRLTKAVEGEIQVRVLIDP-IASPEEIk------ 76  Facklamia languida
WP_003078621  82 nkkvknpdyhKVYDKINQISGVKSITFSGKDEQLEKLKKTMGDDW-----NLFDGdsNPLYDVYIVKTTSPSKVKSVAKT 156 Streptococcus m...
WP_009274055  78 ----------RMETLIKGITGVKSVEFSSKEEELNILIKESgs-----vfERYKDr-NPMPNVFIVEVEKASDIPSITKT 141 [Clostridium] i...
WP_008978183  78 ----------AMEKEIAKMQDVAAVHFSSKEEELDALIKESgs-----vfQRYKDk-NPMPNVFIVEVKEASKIPSVTKA 141 Longicatena cae...
WP_004798178  78 ----------AMQQQIEAIPGVKSLTFSSKEAEMDILIEENgs-----vfQRYKNn-NPLPNVFIVETQTAKQMKAVTKQ 141 Amedibacillus d...
WP_002608053  78 ----------QLLHAIEQLNTVKHVTLSTGKEELENYKAEFQDDst--mfDMYEGkaNPIRDTFLIEVKNGKDIQKTADK 145 [Clostridium] i...
WP_003774428  75 ----------EIQKQIEQLPEVLDVKFSSKENELDAFIRANDSEDaeslyGGYRGenNPMLNAFLINAKSGDEIKDLSNK 144 Erysipelothrix
WP_015536327  79 ----------AIEDQILELSNVDSVEFSDKENELELMIDEKgd-----afSIYKGeeNPLSNAFFVYVQDEKQIQDTSEQ 143 Faecalitalea cy...
WP_003865590  78 ----------DINDKISKLKNVDKVEFSSKDNELELMIKEKgs-----afKAYRGdsNPLSNAFFVYLKDASNIRKTSAQ 142 Holdemanella bi...
WP_016648831  77 ----------ELGEQITQIPAVSRVVYRSAQEELEEYKDVITed-----fDVLNd-eNPLNDMYLVTVTSADKIDEVSSK 140 Facklamia hominis
WP_006308561  77 ----------ALEGEISQLDEVSQVTFQTAEEELETYKEFITed-----fDVLNd-qNPLNDMFLVNVKSAKNIESISHR 140 Facklamia languida
WP_003078621 157 IEkiegVDSVVYGGTDTDRIFGMANFVRTWGLIGTGLLVLVAVFLISNTVRITILSRRNEIQIMRLVGAKNGYIRMPFFF 236 Streptococcus m...
WP_009274055 142 LNnmdgIEKAQYGGESIKDMIDTFETIRYGGAVFVLALGVLAVFLITNTIKMTIYTRQTEISIMRNVGAGNWYIKTPFMF 221 [Clostridium] i...
WP_008978183 142 LNaidgIEKAEYGGESIQHMIDTFSFIRSSGFIFVLALSLIALFLITNTIKMTIYTRNTELSIMRFVGANNAYIKTPFMM 221 Longicatena cae...
WP_004798178 142 LRsldgVANAEYGGEEIESMVEAFEWVRIGGGIFLLALAFVAVFLISNTIKMTIYTRMTEIKIMRNVGATNWYIKMPFMF 221 Amedibacillus d...
WP_002608053 146 IEdmkgIVSAEYGGDSTSGMISTFEKIREGGMIFIIFLIVIAVFLISNKIKMSIYTRKQEIAIMRFVGASNWAIKFPMML 225 [Clostridium] i...
WP_003774428 145 IAkiegVYKTSYGGSGTTDFLGMLEQVRNVGFIIVVTLAVIAVFLISNTIRVSIHSRRREISIMRTVGATNWYIRWPFII 224 Erysipelothrix
WP_015536327 144 IEqiegVSSSAYGGSSVTQLINLLDMVRKVGYGVILLLLILSIYLIFNTIRTTIFSRHEEIIIMRQVGGTNAFIKRPFEV 223 Faecalitalea cy...
WP_003865590 143 IKkidgVASTAFGGDSVTSLVEMLNMIQKIGLGLVALLVILSLYLIYNTIRTTIDSRQDEIMIMRTVGATNGFISNPFIV 222 Holdemanella bi...
WP_016648831 141 ISdldyVLNANVGSLDISGLVTGVKIVRYVIALLAAIFIILAVILISNTIRLAIQTRSREIEIMQLVGAKRSYIRAPFTI 220 Facklamia hominis
WP_006308561 141 IEqmdyVLSANIGSLDLKGFIKTIDIGRYVLAILAGSFVIIAILLISNSIRMTINARSAEINIMRLVGAKRGYIRAPFTI 220 Facklamia languida
WP_003078621 237 EGAWVGLIGAIIPAVVVFYLYHFAYTKFN-PDlanqnlSLYAPNPFIFYVIGAMFVIGIIIGALGSVLSMRRFLK 310 Streptococcus macacae
WP_009274055 222 EGMLIGIIGALLPVILTVFGYGFLYDFFGgQFmss-mfVMQKPYPFTLQIAGILLLSGAAVGIIGSFLAATKYLR 295 [Clostridium] innocuum
WP_008978183 222 EGMCIGILGAILPIALMCIGYSTLYHMLNgYFlss-mfVMQPLYPFLLQLSAVLVGSGALVGVAGSFLATTKYLR 295 Longicatena caecimuris
WP_004798178 222 EGMLIGMIGAILPMILTAAGYNFIYHGLNgTFiss-mfVMQSPHPFATWICLILLASGALVGILGSLHAVNKYLR 295 Amedibacillus dolichus
WP_002608053 226 EGVFIGILGSLVPVLLTIFGYQYVYTILGgTFmsn-mfVLQTVFPMTLEISGILILIGVLVGLVGSFFSTTRYLH 299 [Clostridium] innocuum
WP_003774428 225 EGMVIGLLGAIIPIVISIFGYQYLYQATGgILisq-mfKLVAVYPLSLQISGILALIGIVVGALGSLFSVGKFLR 298 Erysipelothrix
WP_015536327 224 QGVLIGLFGSLLPVAALYFGYAKLYEVLEgQLfsn-lfSLIEPNQIVWQVGLIITLIGLLIGGFASFWAVTKYLK 297 Faecalitalea cylindr...
WP_003865590 223 EGILIGLLGAVIPYLIVHFGYEKLYTSLGgQLftp-mfAMFKPNTIRFQVGFSIILAGVLIGGFASLLAARKYLK 296 Holdemanella biformis
WP_016648831 221 EGAVIGMLGALFASASLYASYQGLITLAHeFLafn-pkLALPIIPYFIYLAVALMLFGSLLGVVGAMRSVRRLVD 294 Facklamia hominis
WP_006308561 221 EGFIIGVIGSLLASFLLFVSYQTLLNLSQkYLsfn-pkYALPLWPDLVIIMGIMLALACVIGYLAARRAVRKHLK 294 Facklamia languida
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