Conserved Protein Domain Family
EAL

?
COG2200: EAL (this model, PSSM-Id:225110 is obsolete and has been replaced by 441802)
EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) [Signal transduction mechanisms]
Statistics
?
PSSM-Id: 225110
Aligned: 227 rows
Threshold Bit Score: 71.5518
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
16124963  138 VHQLEDLIQQMndrlehqlthqVAAASartgardrapqashmlqvvqdalaenrVDLYLQPIVSLP--QRRTVFYESFSR 215  Caulobacter cresc...
15596630  405 ALNDSQDWHDWid-------qaLTERR---------------------------LLLYFQPVVDCLd-TQRVLHHKVLAR 449  Pseudomonas aerug...
15597329   17 AASLAGDLRLArr-------fqAALARg-------------------------rVRLDWQAVRHAGhpEWEPLYRETLLR 64   Pseudomonas aerug...
15600152  440 rgdviaILQQA-----------LETNS---------------------------FRLLFQPVISLR--GDSHENYEVLLR 479  Pseudomonas aerug...
17546062    1 ------------------------------------------------------MSLMHITALARFlgTLPSAPMPDRQL 26   Ralstonia solanac...
16265095    7 FDRVAGAVTQA-----------MREGR---------------------------IGFSLQQVNAVDd-TGEVLYSECLGR 47   Sinorhizobium mel...
15601833    3 KQQWKTLVEEA-----------IHNDW---------------------------FTFRYQAANSSWg---KTFHREVFSA 41   Vibrio cholerae
15837003  304 qnnegiyayvpsqtpentghlaLLDGQ---------------------------LELAYQPIVEVAg--SDTAQYQVLLR 354  Xylella fastidios...
2506685   859 LDEQWRMIKEN-----------QLMMLa---------------------------HGVASPRIPEA----RNLWLISLKL 896  Escherichia coli
2506685   859 ldEQWRMIKEN-----------QLMMLa---------------------------HGVASPRIPEA----RNLWLISLKL 896  Escherichia coli
16124963  216 LRDETG---RVMMPAEYLAVAEPEGLmtaIDNLLLFRCVQIVRRLAkQDRK-----------VGIFCNISL-ASLG-DES 279  Caulobacter cresc...
15596630  450 LLDPQA---TAIAAGRFLPWIERFGW---AARMDLAMLEQSLEHLR-RHPR------------PLALSLSA-ASVR-NAQ 508  Pseudomonas aerug...
15597329   65 VTAASGe--PPLPTQELILALERLGL---VRLLDRCVLGTVLDRLN-AEPT-----------LRLACNLSR-QSAA-MDA 125  Pseudomonas aerug...
15600152  480 LLNPQG---QEVPPAEFLHAAKEAGL---AEKIDRWVILNSIKLLAeHRAKgh--------qTKLFVHLSS-ASLQ-DPG 543  Pseudomonas aerug...
17546062   27 WRDADGrvqGQFFHCALTSLFEPVWR---LDEAGALIPDGHEALMR-TWTRhgegglnpwkmFSLASDDTTlVELDrLCR 102  Ralstonia solanac...
16265095   48 LVERDG---AVRTSEEFTAFLEASGR---VASFDRYMVGLAFEWLDcNPS------------GVLGCDISAgNIFD--EN 107  Sinorhizobium mel...
15601833   42 FEKDGV----RYTANQFLFALEQLNA---SHIFDQYVIERVIQQLEkGELT-----------DPLAINIAQgSISQ--PS 101  Vibrio cholerae
15837003  355 LRKADG---NLLSAGLVIPAAEAEGR---IMELDQQVIEQALDILKlHQDTnq--------qLRLFVSQSVrTLIH--EG 418  Xylella fastidios...
2506685   897 WSCEG----EIIDEQTFRRSFSDPAL---SHALDRRVFHEFFQQAA-KAVAsk--------gISISLPLSV-AGLS-SAT 958  Escherichia coli
2506685   897 WSCEG----EIIDEQTFRRSFSDPAL---SHALDRRVFHEFFQQAA-KAVAsk--------gISISLPLSV-AGLS-SAT 958  Escherichia coli
16124963  280 FFP-QFL--EFMQGnKDLAG--AVFFELGQAAFeRRGP--VEARHMARLASLG-FSFSLDKVNDLDVDFQDLAR--ADVK 349  Caulobacter cresc...
15596630  509 TFA-PLL--ALLKAhPQEAR--QLTLELDERHL-PAAAe--LERLSQVLRELG-CGLGLQHFGGRFSLIGNLTH--LGLA 577  Pseudomonas aerug...
15597329  126 WWEaVCR---WLAArPQVAR--RLTLELTETAV---GErvATREFIRRLREHG-VRIAIDDFGAAHNNLDFVLD--ARPD 194  Pseudomonas aerug...
15600152  544 LLP-WLG--VALKA-ARLPPe-SLVFQISEADA-TSYLk-QAKQLTQGLATLH-CQAAISQFGCSLNPFNALKH--LTVQ 613  Pseudomonas aerug...
17546062  103 LVHtLNYfvRTDARrLVVNVhgRLLAAVAADHGkAFHRavTALGLAPGQFVIQvPSTANDDLGLLLFVVDNYRRngFAVA 182  Ralstonia solanac...
16265095  108 TWS-ELY--DLLSR--NREMasRLVLEITECLP-LATLp-TAAEFIEGARALG-YRIALDSFGTGHSTPESLLS--VPVD 177  Sinorhizobium mel...
15601833  102 FIR-WIS--QTLSKhLSVAN--LLHFEIPEGCF--VNEphYTALFCNAVRNAG-ADFGVDNYGRNFQSLDYINE--FRPK 171  Vibrio cholerae
15837003  419 FSD-WII--KNLQE-RNVNGtgLVIDLRLQDAV-IHTIp--LKQLCKQLLEHN-VQFCLSQFESNSEATVLFSE--LPLN 488  Xylella fastidios...
2506685   959 LVN-DLL--EQLEN-SP-LPp-RLLHLIIPAEA-ILDHaeS----VQKLRLAG-CRIVLSQVGRDLQIFNSLKA--NMAD 1024 Escherichia coli
2506685   959 LVN-DLL--EQLEN-SP-LPp-RLLHLIIPAEA-ILDHaeS----VQKLRLAG-CRIVLSQVGRDLQIFNSLKA--NMAD 1024 Escherichia coli
16124963  350 FLKVGAQMMLDQLEEQDGKlvit----slpdLNASDFAALTRRYGIEVIVEKVEAEKQVAEVLDLDIGYGQGHLFGE--- 422  Caulobacter cresc...
15596630  578 YLKLDGCYLHAVDREGDKR------------LFIEAVYRTTHSIDLPLIAEQVETLGELEVLREMGLRGAMGRLFGS--- 642  Pseudomonas aerug...
15597329  195 VIKIDCRYTREARRSAKGA------------EVLRHLLALCRELAPCVVLEGLEEDDAFARLPTGDVY-LQGNAIAP--- 258  Pseudomonas aerug...
15600152  614 FIKIDGSFVQDLNQVENQE-------------ILKGLIAELHEQQKLSIVPFVESASVLATLWQAGATYIQGYYLQG--- 677  Pseudomonas aerug...
17546062  183 VQASDPAEAGALMVHARPAflkldarrgwqaRHVAGLADSARELGVTLALRRCERPEDLDLARAAGIRYVQGSVLPGaep 262  Ralstonia solanac...
16265095  178 IVKLDAFFIGRGQGVGKGK------------GFLHHLVGLASCVAPTVIIEGIETYGQLEAVKKAGATHVQGFLLSEpt- 244  Sinorhizobium mel...
15601833  172 YVKLDYLFTHHLDDERQKF-------------TLTSISRTAHNLGITTIASRVETQTQLDFLSEHFIEVFQGFIVDK--- 235  Vibrio cholerae
15837003  489 FVRLSQHFGDAHNHPERQK-------------ELPLLIEQAHEHNLHVIGQCIEDAQAATFMWMNGVDLIQGNLFQN--- 552  Xylella fastidios...
2506685  1025 YLLLDGELCANVQGNLMDE------------MLITIIQGHAQRLGMKTIAGPVVLPLVMDTLSGIGVDLIYGEVIAD--- 1089 Escherichia coli
2506685  1025 YLLLDGELCANVQGNLMDE------------MLITIIQGHAQRLGMKTIAGPVVLPLVMDTLSGIGVDLIYGEVIAD--- 1089 Escherichia coli
16124963  423 ----PRAIr-DAVLAEADPPADFI 441  Caulobacter crescentus CB15
15596630  643 ----PAP---WSGDA--------- 650  Pseudomonas aeruginosa PA01
15597329  259 ----PMRV--EPPLSVRRPKSRAR 276  Pseudomonas aeruginosa PA01
15600152  678 ----PSQA--MDYDFSSGDE---- 691  Pseudomonas aeruginosa PA01
17546062  263 aepdPLPGplAAMPARASQAQSCV 286  Ralstonia solanacearum
16265095  245 --lyPVYCg-QPAPLPAAKPRSAG 265  Sinorhizobium meliloti
15601833      ------------------------      Vibrio cholerae
15837003  553 -----VSK---DLNFNFHDMVL-- 566  Xylella fastidiosa 9a5c
2506685  1090 ----A-----QPLDLLVNSSYFAI 1104 Escherichia coli
2506685  1090 ----A-----QPLDLLVNSSYFAI 1104 Escherichia coli
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap