Conserved Protein Domain Family
glyA

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PRK00011: glyA 
serine hydroxymethyltransferase; Reviewed
Statistics
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PSSM-Id: 234571
Aligned: 951 rows
Threshold Bit Score: 492.284
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
78189745    1 MDTDILQKQDA-EVFASIANETKRQ-TETLELIASENFTSRAVMQACGSVMTNKYAEGYPGKRYYGGCEFVDVAENLARD 78 
147919973   1 ----MLNPDVK-TIVDAVEGSQDLF-RHSLPMIASENVTSPMVRKVLSSDLGHRYAEGQVGHRFYQGCGFVDVIEGKAIE 74 
48477683    4 NKKEYLKDAMF-IRDMAMQHEQLFR--ESIPLIASENIMSPLAMEMLLTDLGFRYAEGLPHHRYYQGNEYVDVIEDKTTE 80 
170290605   1 --MDPVEAYGR-VKSSILEHHKWFD--SSLPMIASENVTSPAVRKAMTSDFGHRYAEGWVGERVYAGTKYIDEVESIAME 75 
288932093   1 -------MSVE-EVYEVIRKHTEFY-KNSLPLIASENITSKFVRNCYISDLGHRYAEGKIGERFYEGCSFVDEIELMAVN 71 
11498458   23 YFSSVAEDMNPsDVFQIIEGHTKLM-RDSIPLIASENLTSLSVRRCYVSDLGHRYAEGRVGERFYEGCKYVDQIESMAIE 101
13540878    1 ---MAYQDALS-IRELAQQHNALFG--DSVALIASENVMSPLAREVMISDLESRYAEGLPHHRYYQGNNFVDLIEDKTNE 74 
289595739   1 ---MSLEDALK-IKELVKKHTEWFR--DSLPMIASENLISPMAQEFLISDLHNRYAEGLPGKRYYQGNIYVDQIEELTTE 74 
16082467    6 QRSNSMSYEDA-EYIREMAMKHSEMfGEGIALIASENVMSPLAKEVMISDLESRYAEGLPHHRYYQGNYYVDLIEDRTNE 84 
282162964   1 ----MNSDVQC-VVDAVMGSQELFK--YSLPMIASENVTSPLVRQVLSSDLGHRYAEGQVGHRFYQGCGFVDTIEAKAIE 73 
78189745   79 RAKKLFGCEYVNVQPHSGSSANMAVLFSVLKPGDKIMGLDLSHGGHLTHGSS---------VNFS-GQMFEAHSYGVDRE 148
147919973  75 LAKEIFRAPHVNVQPVSGVNCNIAAFFALADPGDKLMALAVPSGGHISHAKF---------SAAG-IRGLKIYTHPYDNQ 144
48477683   81 LGKRLFNSKTFDPRPLSGTNANMAVLYALTEPGDKISVPPLSGGGHISAAKF---------GAVG-FRGLKTVQYPFDIN 150
170290605  76 LVKRLFNVKFADVRPISGVVANLAVYTAFTNPGDVAMALPITKGGHISMGPLrgsegqfigGTAGaVRGLDVKYLAFDDH 155
288932093  72 LMKELVKAPHVNVQPISGVVANMAGFFALTNPGDKIFALSIPSGGHISHEKY---------SAAG-LRGLQVLHYPFDAE 141
11498458  102 LTRKIFEAEHANVQPISGVVANLAAFFALTNVGDTIMSISVPCGGHISHDRV---------SAAG-LRGLRVIHYPFNSE 171
13540878   75 LLSKLFKTEQTDPRPISGTNANSAAIYALAKPGDLVAVPALSGGGHISAAEF---------GILG-MRGVRTISYPYDKN 144
289595739  75 LAKKLFKVDYADVRPISGTNANQAVLFALTKPGDVITGPPLQGGAHISSAKF---------GAVG-MRGVHKIEYPFDVE 144
16082467   85 LLSKLFRTSQTDPRPISGTNANSAAIYALAGPGDLVATPSLSGGGHISAAEF---------GILG-MRSVRTINYPYDMD 154
282162964  74 LAKEVFRAPHVNVQPISGVNCNIAAFFALAQPGDKLLALAVPSGGHISHAKF---------SAAG-IRGMKIYTHPYDNS 143
78189745  149 TGCIDMNKVEEMAMQVRPKLIIGGASAYSQGFDFKAFRAIADKVGALLMADIAHPAGLIAAGLLPNPLQ-HCHFVTTTTH 227
147919973 145 IMNIDVDRMIKQIREIRPRVVMFGASLFLFPHPVKEAREVCDEVGASIVYDGAHVLGLIAGGQFQDPLReGADVVTGSTH 224
48477683  151 EMNIDIDGTIKTIKNERPKVCWFGQSVFLFPTPLKELQDAFNEVNARVVYDGAHVAGLIAGGEFQDPLReGAEIITGSTH 230
170290605 156 NMNVDVDKSIKRIEENKPKLVILGGSVILFPHPVKELSDVCKSVGALLHYDAAHVAGLIAGKQFQQPMEeGADVMTMSTH 235
288932093 142 IMNIDVDETKKLAEKEKPKLFVLGGSLFLFPHPVKEISEIAAEINAKVMYDGSHVLGLIAGGEFQNPMEeGADVLTASTH 221
11498458  172 EMSVDVDETRKVAERERPKLFILGSSLILFRQPVKEIREIADEIGAYVMYDASHVLGLIAGKAFQNPLKeGADVMTGSTH 251
13540878  145 TMTVDPDEASKIIKREKPKVCLFGQSVFMFPVPLKEMKGAFDEVGCKVWYDGAHVLGLIAGRKFQDPLReGADIVTGSTH 224
289595739 145 EMNIDVDMSAKLIKIVKPKVALFGMSVFLFPAPLKELQDAFQEAGTTVWYDGAHVLGLIAGGQFQDPLReGAHVMTGSTH 224
16082467  155 TMTIDPDQASKMIIKEKPKVCLFGQSVFMFPAPLKEMAEAFHEVGCKVWYDGAHVLGLIAGGRFQDPLReGADIVTGSTH 234
282162964 144 KMNIDVDGMVKEIKRLKPKVVMFGASLFLFPHPVKEAREACDEVGASIVYDAAHVAGLIAGGEFQDPLKeGADVVTASTH 223
78189745  228 KTLRGPRGGMIMMgsdfenplgitiktktgsRV-KMM------SEVMDAEVMPGIQGGPLMHIIAGKAVAFGEALQPAfK 300
147919973 225 KTFPGPQGGIILC------------------KE--KF------AKDIDEAVFPGTVSNAHLHHKAGLAITLAEMKAFG-K 277
48477683  231 KTLPGPQHGMIIG------------------NTdDDT------WKKVQRGVFPGTLSNHHLNAMAALGVTLAEELDFG-R 285
170290605 236 KTFFGPQHGAVIT------------------ND-EEK------FERIKLANFPGLLSNHHLHSVAALALAAAEMLAFG-E 289
288932093 222 KTFFGPQRAIIAC-------------------R-EEL------ADRVDKAVFPGVVSNHHLNTLAGLVIAAMEFKEFG-R 274
11498458  252 KTFFGPQRAIIAS-------------------R-KEL------AEKVDRAVFPGVVSNHHLNTLAGYVVAAMEMLEFG-E 304
13540878  225 KTFPGPQHGVILG------------------NTdSET------WKSVRRAVFPGVLSNHHLNAMAALGITAAEELEFG-E 279
289595739 225 KTLPGPQRGMILA------------------NPpGDEekrdkfWKKIQRGVFPGVISNHHLHHMAALAITLAEHIEFG-K 285
16082467  235 KTFPGPQHGVILGn-----------------TD-DET------WKAVRRAVFPGVLSNHHLNAMAALGITAAEELEFG-K 289
282162964 224 KTFPGPQGGIILC------------------KE--KW------AKDIDEAVFPGTVSNFHLHHKAGLAIALAEMKQFG-K 276
78189745  301 EYAAQVMKNASTMASRFMELGYTIVS---GGTKNHLMLLDLRNKNVTGKEAENLLHEAGITVNKNMVPF---DD-KSPFV 373
147919973 278 QYAAQIVKNSQALGAAMDDLGFNVLCkdlGYTKSHQIAVDVSKIG-GGSVLASKLERANIITNKNLFPWd--DV-NTTDN 353
48477683  286 DYAKQIVKNARHLGEKLYEFGFNVLGeknGFTRSHTLAVDVSKN-GGGRKVAENLEKSGIILNKNLLPWd--DN-KNSQN 361
170290605 290 EYARAVVRNAKALAQALHDEGFSVVAehlGFTQSHQVLLDVDAL-GGGHRCEKLLEEANIIVNRNLLPWdikRG-RSFKD 367
288932093 275 DYAEQTVKNAKRLAEELAEEGLKVLGedlGFTESHQVAVDVRKQG-GGAKVAKKLEKANIILNKNLLPW---DSiKDTEN 350
11498458  305 DYAKQVVRNAKALAEELYSLGYKVLGekrGFTETHQVAVDVREFG-GGERVAKVLENAGIILNKNLLPW---DSlEKTAN 380
13540878  280 KYASDIIDNAKALAGELYSLGFKVLAeerGFTESHTMAVDVTQN-GGGKYVAETLEASGIILNKNLLPWd--DN-KKSQN 355
289595739 286 QYAEQVVKNAQTLAQELYELGFKVLGeknGFTKSHTVLVDVVAQ-GGGRKVAEDLEKANIICNYNLLPYd--DP-KKPRN 361
16082467  290 RYADDIISNAKVLAEELYANGFNVLAekrGFTESHTMAVDVSKNG-GGKYVAETLEKCGIILNKNLLPWd--DN-KKSQN 365
282162964 277 AYARQTVKNAQALAASMDDMGFSVLCkeqGYTKSHQVAVDVSKI-GGGSVVAANLEKANVIANKNLFPWd--NV-NGTDD 352
78189745  374 TSGIRIGTPAMTTRGMKEAESRRIAELIDQVI--TSaskpdisAICEAVREEIKTICHNNPIEGY 436
147919973 354 PSGLRLGTQELTRLGMNEPEMKEVAKFIKRVA--IDk------EEPEKVKKDVVHFKSQYQAVKY 410
48477683  362 PSGIRIGVQEITRIGFMEDDVTELAEILRDAV--INe------KPVNEIRRRALELKSRFNNIEY 418
170290605 368 PGGLRLGVSELTRLGMGEEEMKEIAKLYRKVL--LDr------EDPKKVAGEVSELRKRFRNVKY 424
288932093 351 PSGIRIGVQEVTRLGMKESEMDVIAKLIADVIl-DR-------RSVDKVRKDVISLKKEFSKVKY 407
11498458  381 PSGIRIGVQEVTRIGMKEEEMRAIAEIMDAAIkeK--------KSVDELRNEVKELKERFNVIKY 437
13540878  356 PSGIRIGVQEVTRTGMGKSEMKEIASLIYRAI--VKk------EEPSKIKEEVKDLKSSFRHVKY 412
289595739 362 PSGIRLGVQELTRLGMKENEMKYVAELIKRVA--Vd-------GDIEGVKKDVKELKEEFNTIHY 417
16082467  366 PSGIRIGVQEATRVGMGKSEMKEIASLITRAI--IRh------EDPEKIKAEVKQLKSGFREVKY 422
282162964 353 PSGIRLGTQELTRLGMKEPEMKEVARVLKRVA--IDk------EKPEKVKKDVILLKSQYQTVQY 409
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