Conserved Protein Domain Family
Pep3_Vps18

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pfam05131: Pep3_Vps18 
Pep3/Vps18/deep orange family
This region is found in a number of protein identified as involved in golgi function and vacuolar sorting. The molecular function of this region is unknown. The members of this family contain a C-terminal ring finger domain.
Statistics
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PSSM-Id: 461557
Aligned: 110 rows
Threshold Bit Score: 105.293
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_001385531  286 ILTNDE-----------------EILLSQAEKLDTSKI---NENISLSSNSIIVTPHHLVTFNDahDKLISFNKLslsna 345 
XP_003671257  265 GIVFGDlepstkakvnqpiedtkPTILKDAKILLNIEL----SDSKYKIKDVIMTKFHIIIIRG--FTITIINQL----- 333 
XP_002497819  247 FGKLGGn----------------QNILNNAKVLLTVEL----PESTHDIKDIILTEFHIVLLRG--ATILIINQL----- 299 
CCE93294      237 GIVFGSin-------------nrAKVLSNAKVLLAVEL----TESKYSIRDIIMTDYHIIILRG--WTVTIINQL----- 292 
Q6FJP4        258 GIVFSNveqv---------kksnKKVLGSSKVILNVEL----PNSKKPIRDIILSDYHILILRE--SSITIVNQL----- 317  [Candida] gla...
CCK67969      239 GIIYGDlaqe---------gfdqGNKLGSLKMILSMEL----PDSPHHIKDLTISDYHVFILRG--PTVLIINQL----- 298 
CCH58213      257 GIVYEEivks----------sekNNILSDANVFLNIEL----PQSNFNIRDIILTQFHIMLLRG--STITVINQL----- 315 
CCF59618      237 GIVYGNldv--------------dstINSFKIYLNVEL---PNSDRYQIKDLILSDYHMVLLRG--SLITIINQL----- 292 
P27801        214 GIVFGDlkekqmek--dpasnnfGKFLSSSKVLLNFELpdyQNDKDHLIKDIVLTAFHILLLRK--NTVTMVSQL----- 284  Saccharomyces...
XP_003684649  277 KTFTNSn----------------RKILLDANLFLNVEL----TERQKIINDIIMTDFYLILQRD--TLITVINRL----- 329 
XP_001385531  346 sSPPVELNlKSF---------CNPGeYLFGITADfkN-----NTYWIFSNNSIYELIIRNEAVSVWYNYYKMGKFEEALK 411 
XP_003671257  334 -DNSIVFE-ESIwd-----nkDTSSgKLLGLAAD--Ysq-slPTFWCFSNTNIYEIILNKESNAIWKLLCDQKKFDVALS 403 
XP_002497819  300 -NNAVVFE-ESIwt--------qkSeKMIGLTAD--Ysq-npPTFWCFSSSNIYEIILHDEAKAVWRLMCEQREYDRALQ 366 
CCE93294      293 -SNAIVFE-ESIls--------eaGeRMIGLTAD--Ysq-etATFWCFSNANIYEIILHNESQAVWKLLCNQKEYDTALN 359 
Q6FJP4        318 -DNSVIYN-QSIws--------ndNeHILGFASDvhYk---qATFWCFSASNIFEIILKKESNSVWRLLCDQQRYDDALN 384  [Candida] gla...
CCK67969      299 -SNKVVFN-ETIyn-----deNQ-PeKIVGLTVD--Qt---qSTFWCFSSRNVYEIILKGESKAVWKLLCEQGEYGEALA 365 
CCH58213      316 -NNEIAFD-ETIpi--------teQeKILGITSD--YsdihhPTFWCFSNNNIYEIIIKKEANSVWKMLCVNGQYEKALS 383 
CCF59618      293 -SNKIIFE-QSIde--------gnNeKFLHLVKD--Nv---sLTYWCFSNMNIYELVLSDESKSIWKLLCEENRFEEALK 357 
P27801        285 -NNDVVFH-ETIprhqltgsnTDSNeKFLGLVRD--Sv---kETFWCFSNINVFEIIIENEPNSVWNLLVRDNKFDKALS 357  Saccharomyces...
XP_003684649  330 -TNEIVYEeELL---------LNESeNIIGLTAD--Hsq-evPTYWCYSNLHVYEITISNKSHSVWKILCKQNKFNTAQS 396 
XP_001385531  412 CLEennnngsnssDLYKIDLILIKQGYNYLQ 442 
XP_003671257  404 LKDs--------lNQFQIDSILLYKGEHLLL 426 
XP_002497819  367 LKg---------lTGWERENIYYKKGLHLLK 388 
CCE93294      360 LKg---------lTGLVKQTLYYEKGCHLLN 381 
Q6FJP4        385 LQd---------lSLFEQSSIQYLKGMHLLE 406  [Candida] glabrata
CCK67969      366 LKd---------lNSWEYDYIQYQRGTAFMK 387 
CCH58213      384 LEg---------lSSIERSNIFQEMGEYYFK 405 
CCF59618      358 LGg---------lNTDEIQLIYYNYGKYLLE 379 
P27801        358 LKg---------lTVREIESVKLSKAMYLFH 379  Saccharomyces cerevisiae S288C
XP_003684649  397 LLd---------iNNMEKDMIMHNKGDFLFE 418 
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