1YQE


Conserved Protein Domain Family
tRNA_deacylase

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pfam04414: tRNA_deacylase 
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D-aminoacyl-tRNA deacylase
Several aminoacyl-tRNA synthetases have the ability to transfer the D-isomer of their amino acid onto their cognate tRNA. D-aminoacyl-tRNA deacylases hydrolyse the ester bond between the polynucleotide and the D-amino acid, thereby preventing the accumulation of such mis-acylated and metabolically inactive tRNA molecules.
Statistics
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PSSM-Id: 427935
Aligned: 85 rows
Threshold Bit Score: 166.192
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1YQE_A        68 YIDFEEILFASRHSSKDG-RKIFTVHVSG----NVGT-ADFGGKPYSLAKPSPQtMKNYVLALRERL---DRKPEFEFTM 138 Archaeoglobus f...
CBH22548      80 FEDFDIAAMVNWHGGQNApDKVLCIHTVG----DLAS--------ARYSPSNPVpSTNLAKALEHHRe-rLNLEEFKVTT 146
XP_001765259  69 GENVSEIIFMSRHTAASN-RPALTVHPIGiphlEHDAnSPAGGKPGRASPPNSR-IGAWFRLLKSTAannNLLPEFEVTL 146
CBI15350      68 GEVVEEAIFLSKHTAVSN-RPSLTVHPIGvphlRDDEvPPQGGKPGWAAPPSPR-IGPWLRLLKTIAqsqNLIPEFEVTL 145
XP_006363560  69 GQTVDEVIFLSKHTAVSN-RPALTIHPIGvphlKEGDvPPQGGKPGWAAPPNPR-MGPWMILLNKIAeshNLIPEFEITF 146
KRH59444     129 GEVIDEVIFFSKHTAASN-KPALTVHPIGvphlRQGDvPPQGGRPGWAALPNPR-MGPWLRLLKNLAqahNLVPEFEITL 206
Q9ZPQ3        69 GEVVDEVIFLSRHTAVSN-RPALTVHPIGvlhlKDGEsPPQGGKPGWAALPSTR-IGPWFRLLKKMAeahGLVPEFEITL 146 thale cress
XP_002512027  45 GEVVEEVIFFSKHTAVSN-RPALTIHPIGvphlRQGDvPPQGGKPGWAAPPDPR-MGPWLRLLKKIAdshHLLPEFEITL 122
XP_003573407  69 GEAISEVIFLSKHTAVSN-RPALTVHPIGvphlREDEtPPQGGRPGWAALPNPR-IGPWLRLMQQIAadqGLVPEFEITL 146
XP_006844059  68 GEVVDEVIFLSRHTAVSN-RPALTVHPIGaphlRENEiPPAGGKPGWAAPPNPR-IGPWLRLLKSVAeshDLTPEFEVTL 145
1YQE_A       139 EVTHHGPSe----------ISKPSAFYEIGSTEEEWKDREAAEVVAEAMLDAIRAE------------KMDWNVAVGVGG 196 Archaeoglobus f...
CBH22548     147 EATHWSGIvydgksewieeSKLPFLDIEIGSTSESYNNPVAASVIAFALMDAFASE-------------EKAPTVLYMGG 213
XP_001765259 147 EATHHGPW-----------TEVPAMFVEIGSTEDYWRREDAAATVASVFMKGLGLDgdqavgcwseeiHAGEKVLLGIGG 215
CBI15350     146 EATHHGPE-----------INSPTMFVEIGSTEEHWKRQDAAQVVASLIWEGLGLGggvkvg-dwnrnDGNNKVLLGIGG 213
XP_006363560 147 EATHHGPV-----------TTKPTMFIEIGSTEEYWRRPDAAQVVAQLVWEGLGLGggppvg-nwsstSANNKVLLGIGG 214
KRH59444     207 EATHHGPL-----------TNKPTMFLEIGSTEDYWKRQDAAQVMAQLVWEGLGLGgvsdvg-nwsreNDNKKILLGIGG 274
Q9ZPQ3       147 EATHHGPI-----------TNKPTMFLEIGSTEEYWKRQDAAQVMALLMWEGLGLGgseevg-kwkseTGKRKVLLGIGG 214 thale cress
XP_002512027 123 EATHHGPV-----------TNKPTMFIEIGSTEEYWKRQDAAQVIALLVWEGLGLGggpsvg-nwssaHDKRTVLLGIGG 190
XP_003573407 147 EATHHGPL-----------TNTPTMFVEIGSTEEYWGRQDAAQAIALVLWKGLGLEegkavg---twtgnGEKVLLGIGG 212
XP_006844059 146 EGTHHGPV-----------VTAPTMFVEIGSTEEYWKRQDAAQAIALLLWRGLGLDgcggvg-iwngnEARNKVLLGIGG 213
1YQE_A       197 THYAPRQTEIML-TT-TFTFGHNFAKY------------------TFEHLTAeFLVKAVKLS------EAEYIIIDEKSV 250 Archaeoglobus f...
CBH22548     214 VHFEDTITNAVLhKShPVSLTHILPSRw----------------lENEMYMGeDARDYLMKCidsihgSIDGIVIHEK-L 276
XP_001765259 216 GHYAPRHTDIAQ-KD-GVWVGHLLSGYsllmsdpg--anvkdydkIEGTWKE-AILEAVSATkrafpgGEVVAHLDGKSF 290
CBI15350     214 GHYAPRHMDIVR-ND-GVWVGHLLSGYalpmedpgkskaqgnakdVGGTWKH-AIKVAYEVTkssfpgGEVLAHLDQKSF 290
XP_006363560 215 GHYVPRHTDVIK-KD-GCWVGQLLSGYslpmedpgpskgkvnaqdIAGTWKH-SIRAAYDATkagfpgGEILAHLDQKSF 291
KRH59444     275 GHYAPRHVDVVL-KD-NVWVGHLLSGYslpmedpnq-skgeknveIGGTWRQ-SIKAAYEATysafpgGEILAHLDHKSF 350
Q9ZPQ3       215 GHYAPRHMDIAL-KD-DIWVGHLLSGYslpmedptqtkttpgenyIGGNWRQ-SIKAAFEATkasfpgGEILAHLDHKSF 291 thale cress
XP_002512027 191 GHYAPRHMDIVL-KD-GVWVAHLLSGYslpmedpsqtkkdsstkdIGGTWRE-AIKAVYEATqsafpgGEILAHLDHKSF 267
XP_003573407 213 GHYAPRHMDIVI-KN-GAWVGHLLSGYslpmeapp--egnskgsgVGGMWKH-SIKASFEATkaafpgGEVIAHLDQKSF 287
XP_006844059 214 GHYAPRHMDVVL-KD-GVWAGHLLSGYslpmddpgpskesncaagVRGTWKQ-AIKVAHEATklafpgGEIVAHLDNKSF 290
1YQE_A       251 NSAVKKIVNEAAEVAGV 267 Archaeoglobus fulgidus
CBH22548     277 KREIKDHVEIIAEILSI 293
XP_001765259 291 KAWQRNAITWFLGKKNI 307
CBI15350     291 KSWQKNAITEFLTEQNI 307
XP_006363560 292 KSWQKNAIIEFLGAQNI 308
KRH59444     351 KGWQKNAITGFLAEQNI 367
Q9ZPQ3       292 KGWQKKAITEFLAEESI 308 thale cress
XP_002512027 268 KNWQKNAIIGFLGEQNI 284
XP_003573407 288 KGWQKNAITSYLQEENI 304
XP_006844059 291 KSGQRNAVTSFLAEENI 307
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