P40004 3 NSLKAFALVFGGCCSNVITFETLMSNET-GSiN---------NLITFCQ-----FLFVTCQGLPEFLDvhqpfpY----- 62 Saccharomyces cerev... Q869W7 7 ISLIPISMIMVGCCSNVISLELIMKQSQ-SH-A---------ILVTFFQ-----FATVAFISFFVNIRwkqvfsIfwi-p 69 Dictyostelium disco... Q9VAN9 6 RAISAICGVFLGCCSGVVFLELLVKLDP-GA-G---------NLITGAQ-----FAFIALEGF-----------Ifts-k 57 fruit fly Q9W429 6 KALLGMLFVFIGCCSNVVFLELIIQIDP-GA-G---------NLITFAQ-----FLFIALEGL-----------Vfts-k 57 fruit fly O64503 13 LLALCISGIWSAYIYQGVLQETLST----KRfGpdekrfehlAFLNLAQsvvclIWSYIMIKLWSN-------------- 74 thale cress Q6NMB6 18 KGVFAVSGIMSTLVIYGVLQEKIMR----VPyGvnkeffkhsLFLVFCNrl--tTSAVSAGALLASKK------------ 79 thale cress OCA15007 122 kLLFCAAGLQVSYLTWGVLQERVMTRTYgSEeGspgerfrdsQFLVFMNr----ILALTVAGVYCSIS------K----- 186 tropical clawed frog Q29Q28 22 QFLICTSGFFFGYLVNGVCEEYVYNRLQ-FSfG---------WYFTFIQgfvylFLIY-LQGFT---------------- 74 thale cress Q20787 41 QFVLLSLAIFILYIGYGYMQELIFKLPGmKPfG---------WTLTLIQ-----FLIYSGCGYTECIIw----------- 95 Caenorhabditis elegans Q9VVD9 61 QFLLSCAGVFFLYILYGYLQELIFTVEGfKPyG---------WFLTLVQ-----FGYYIGFGLVERRLegyrisGgsfwn 126 fruit fly
P40004 63 --FKPLKTPLHVYVITVVLFYISSTTNNNVFKYNISIPIHIVFRCFGTVITMFTCWLLNG--RKYTKIQILSTLFLTIGA 138 Saccharomyces cerev... Q869W7 70 igLRERKIPLKTYFLMVSIFFILSVLNNKALDCDIPIPFHMIFRSSSLLSTIVIGSIFYR--KSYSKQQILSLIMVTLGI 147 Dictyostelium disco... Q9VAN9 58 fgLAQRVISLRDYALLVAMFFLTSVCNNYVFKFKVPMTLHMIIRGGSLISNMCLCTLILK--RSYRLSQYISVLMISVGI 135 fruit fly Q9W429 58 ffTVRPKIALKDYVILVALFFGANVCNNYAFNFNIPMPLHMIFRSGSLMANMIMGIVLLK--KRYNLRQYSSVAMITAGI 135 fruit fly O64503 75 --AGNGGAPWWTYWSAGITNTIGPAMGIEALKY-ISYPAQVLAKSSKMIPVMLMGTLVYG--IRYTFPEYMCTFLVAGGV 149 thale cress Q6NMB6 80 --VLDPVAPVYKYCLISVTNILTTTCQYEALKY-VSFPVQTLAKCAKMIPVMVWGTLIMQ--KKYKGFDYLVAFLVTLGC 154 thale cress OCA15007 187 --QPRHGAPMYKYSFASLSNILSSWCQYEALKF-ISFPTQVLAKASKVIPVMLMGKLVSH--KTYEYWEYLTAVLISVGV 261 tropical clawed frog Q29Q28 75 --TKHIVNPMRTYVKLSAVLMGSHGLTKGSLAY-LNYPAQIMFKSTKVLPVMIMGAFIPGlrRKYPVHEYISAFLLVLGL 151 thale cress Q20787 96 -hNTKRMIPWRIYGVIAFFTVATMGLSNASVGY-LNYPTQVIFKCCKLIPVLIGGILIQG--KRYGWIDIGAAMLMSLGI 171 Caenorhabditis elegans Q9VVD9 127 iePEPRCIPMRTYLILAALTLGTMGLSNSSLGY-LNYPTQVIFKCCKLIPVLVGSILIQG--KRYGLLDFAAATCMCIGL 203 fruit fly
P40004 139 IIASLFKDADFryqdlklqawkiGSDqsvDLT-FIFGICILVLSSFTSSLLSAYNERTYQKYGKHWK-ENIFYSHFLSLP 216 Saccharomyces cerev... Q869W7 148 IFATFSSMPDSkkei-----slgHEP---NLLrFSIGMLMLIAAMFLSSILGLIQEHTYKLYGKDRHyETIFYSHLFSLP 219 Dictyostelium disco... Q9VAN9 136 FVCTYFSSPDLvgkmenldsgaeADT-----FwWLLGVALLVLALFVSSYMGITQELLYRRHGKCAR-EALYYTHLLPLP 209 fruit fly Q9W429 136 ILCTLVSSGDVkdnth---hslkVDTsysDFFwWTVGIGLLTIALLVTAYMGIYQEVIYKKYGKHPS-EALFFTHMLPLP 211 fruit fly O64503 150 SIFALLKTSSK-------------TIsklAHPnAPLGYALCSLNLAFDGFTNATQDSIASRYPKTEAwDIMLGMNLWGTI 216 thale cress Q6NMB6 155 SVFILFPAGDD------------VSPynkGREnTVWGVSLMAGYLGFDGFTSTFQDKLFKGYNMEIH-NQIFYTTLCSCV 221 thale cress OCA15007 262 SMFLLSNG----------------GGnrpSGVtTFSGVVILSGYIVFDSFTSNWQDSLFK-YKMSSV-QMMFGVNLFSCL 323 tropical clawed frog Q29Q28 152 ILFTL-------------------ADaqmSPNfSMIGIMMITGALIMDAFLGNLQEAIFTMNPETTQmEMLFCSTVVGLP 212 thale cress Q20787 172 IMFTL-------------------ADnkvSPNfDSRGYIMICGALLADAVIGNIQEKNMKKYGGSSN-EMVLYSYGIGSV 231 Caenorhabditis elegans Q9VVD9 204 AWFTL-------------------ADsqmTPNfNLLGVAMISGALLCDAAIGNVQEKAMREFKAPSS-EVVFYSYGLGFV 263 fruit fly
P40004 217 LFL-----FSRKQLIHEYRVMRKSERILCsnf---ggkILVPREETLLLFNVLTQYFCVKGVNILASKTNALTLSITLLV 288 Saccharomyces cerev... Q869W7 220 FFL-----LFKDDILHHIQLNNDSALMALpf-----gfGSFPTLWVYLIVNVLTQYVCIQGVFILTGKTSTLTCTLVISI 289 Dictyostelium disco... Q9VAN9 210 AFL-----LMHDDIRTHWLLAFTGESYQLpl-----lgVAVPLILLYLLGNVLAQHLCISSVYTLTTECSSLTVTLILTL 279 fruit fly Q9W429 212 GFL-----IMAGNIVQHFGIAWSSEPVAVpllgaigleWKFPLMLFYLLCNVVTQYVCISAVYVLTTECASLTVTLVVTL 286 fruit fly O64503 217 YNMiymfgLPQGIGFKAIQFCKLHPEAA-----------------WDILKYCICGAVGQNFIFMTISNFGSLANTTITTT 279 thale cress Q6NMB6 222 LSFtg--lILQGHLLPAVDFVSLHRDCL-----------------LDIALLSTVATASQFFISYTIRTFGALTFAAIMTT 282 thale cress OCA15007 324 FTVgs--lLEQGALLEAVHFMSRHPDFA-----------------FHAALLSVCSAFGQLFIFYTINKFGAAIFTIIMTL 384 tropical clawed frog Q29Q28 213 FLFvp--mVLTGEVFRAWTACAQHPYVY-----------------GVLVFEAMATFIGQVSVLSLIALFGAATTALITTA 273 thale cress Q20787 232 FIFaf--vVLSGEVFSAIPFFLENSWKTF----------------GYALILSCLGYLGVNVVLTHIKVFGALVAVTVTTL 293 Caenorhabditis elegans Q9VVD9 264 YLFvi--mLVTGNFFSGFAFCLEHPVETF----------------GYGFLFSLSGYLGIQFVLALVRSSGAPIAATVTTA 325 fruit fly
P40004 289 RKFISLLLSVRLFDNNLSYTGYIGVYLVFFGAFIYSLGS 327 Saccharomyces cerevisiae S288C Q869W7 290 RKFLSIIISVIYFNNHFTSLLFTGTILVFLGTFMYSTSG 328 Dictyostelium discoideum Q9VAN9 280 RKFISLVFSIVYFRNPFTWWHWLGTALVFVGTLMFANVI 318 fruit fly Q9W429 287 RKFVSLLFSIIYFRNPFTLNHWVGTILVFFGTILFANVI 325 fruit fly O64503 280 RKFVSIVVSSVMSGNPLSLKQWGCVSMVFGGLAYQIYLK 318 thale cress Q6NMB6 283 RQLASIMLSCIWFSHPLSWEQCIGSVIVFGSLYAKNLLN 321 thale cress OCA15007 385 RQALAILLSCLLYGHPVTAVGGVGVAVVFLALFLRVYAr 423 tropical clawed frog Q29Q28 274 RKGVTLLLSYLIFTKPLTEQHGSGLLLIAMGIVLKMVPM 312 thale cress Q20787 294 RKALTIILSFMLFSKPFTIEYVYAGSVVMLAIYLNLYSK 332 Caenorhabditis elegans Q9VVD9 326 RKAVTIAFSFVLFSKPFTLQYLWSGLIVVLGIYLNVYSK 364 fruit fly
Jiyao W et al.(2023). "The conserved domain database in 2023.",