3K0B,3LDU,3LDG


Conserved Protein Domain Family
RlmL

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COG0116: RlmL 
23S rRNA G2445 N2-methylase RlmL [Translation, ribosomal structure and biogenesis]
23S rRNA G2445 N2-methylase RlmL is part of the Pathway/BioSystem: 23S rRNA modification
Statistics
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PSSM-Id: 439886
Aligned: 475 rows
Threshold Bit Score: 206.875
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3K0B_A        15 FQ---LVATAASGLEAIVGKEVARL-GY-D--PKVENGKVYFE-GDLSAIARANLWLRVADRVKIVVGV-FKATT----F 81 
ADM28083      21 VT---LLLTCDTGLETLLLDEISSLvdi--dnYYMFPGRVFIT-ISNDRIAn-VFRSRIVNNIYLLLFI-SNNIDs---L 89 
BAJ50996       1 MR---FFATTFSGLEDIAAAELSNLlSGe---AEADVGKVFFT-ASLEECVKVNYAAQTVNRIFLLLLR-EHAET----L 68 
WP_012843871  25 NP---PVVSCAAGFEPVVAEELRELg-HtacyLKP-AKLVLPE-AGPDASLPLNFFGRTLHRVYLLLGL-GRAPT----L 93 
WP_011322159   1 MQ---LLATTNGGLESVAAAELRELtGAeA--TRHHRGVVAFE-GTVEDVYELHYRARSLHRIMAVLVD-TPVAG----L 69 
WP_010869937   1 MD---YYVTLSPGLEKISKNEIESF-GGkIkeIRENKGRIFFS-GDLKLIPKINYLSRTIERMNILLHR-EEIPNi--aL 72 
WP_013798288   3 FK---YYATLPPGLEKISSDEIEEL-GGrIfrIKEGKGRIFFE-GDFELIPKVNYLSRTIERTIILLKL-EEFENi--tL 74 
WP_068548645  14 LK---VLFSTERGIEELLALSIKGAvdk-ipvPFNFQGRVLCYfQDEKAILENLYTNPLYHKASLLLLI-TAIPMdrnaL 88 
WP_119725704   1 MK---FVLSTIAGVESIAKKEIEKV-GGkI--EQTTDRIITFS-GDIDLMVKVNLWSRVGNKLYILLAEeDDVTD----F 69 
WP_114983139   2 IEngiFHAKTHHGLEALLQAELERA-GAeY--IFALPGAVRFQ-AADEQLYRFLLQTRLTTGLELCLSQ-PLDIT----Q 72 
3K0B_A        82 DELFEKTKALPWEDYLPLDAQFPVAGKSVKSTLYSVPDCQAIVKKAIVNRVSEKYRRSGRLX--ETGALFKLEVSILK-D 158
ADM28083      90 DKIYNVIRSIDFSHTIYPHESFAIRSERIGQHtFTSIDIARVAGQAVIDSYMASRGVRLKVN--LDNPDIEIYTELNN-D 166
BAJ50996      69 DEIERLAASVDFGEFIDREQSFAVRAERVGLHvFTSLDIAAAVGKAVIDSYRASTGVRLRVD--LNNPDIEVYAILRN-T 145
WP_012843871  94 QDVRALAQTVPFHAYLHPEQRFAVRAQRHGSHdFTSMDVAREVGSAVVERVQAHTGRRIRAD--LDTPDVEIMAELSD-D 170
WP_011322159  70 DDIYATTADMPVADRLp-EATFGVVGTRHGTHeFTSMDVADRVGQAVIDAYREATGTRLPVD--LDDPTVRLEAYLYD-E 145
WP_010869937  73 DDIYKRVYNIDWTEWIKENQSFAIRPLRAGEHnFTSIDIGRVAGEAVIKSYQRDKNIRLKVN--LDEPDVIVRVEVIF-D 149
WP_013798288  75 DDIYKSVYEIDWTEWIREEQAFAIRPLRAGEHdFTSIDVGRVAGQAVIDAYKNAKGVRLKVN--LDNPDVIIRVDVIF-N 151
WP_068548645  89 DTVYEEVFNSSIDQLLSPSTTFGVRCVRKGFHpFYSQEVAAYAGAAVIDACRVRRGFRPRVN--LKDPDLIVNADVVN-D 165
WP_119725704  70 EYFFEIIKKISFKKYFKNNNPIIVKSSSTRSELFSPRTMQSLCKKAIVDSLVGKGNI-YNED--EKSEPIEILALLVD-N 145
WP_114983139  73 TDLPGLVASVDWTEVLPVHSTYRVQAFEDGVTgVGLQKLATELERGIGQVFQQKFEAEPKVVkeENEPEFVVNIQISSnG 152
3K0B_A       159 EVTLTIDTSG-AGLHKRGYRLAQGSAPIKETXAAALVLLTSWHPD-RPFYDPVCGSGTIPIEAALIGQNIAPGFNR-E-- 233
ADM28083     167 RLLVGLALTR-RSLHIRN-RLFYHPASLKSSIAAAMLRYAEWRPE-IGIVDPMCGSGTIPIEAALIAKGVEVPCINiN-- 241
BAJ50996     146 ELLLGVNTTG-ESLHRRFYRRGFHRAALSPTVANTLVRLSGWRRH-MVLLDPFTGSGTIPLETALYGLAISPGARReN-- 221
WP_012843871 171 QLLLLLNTSG-PPLHRRHHRAFQHFAPLLPTLAAALLRLSSFPNNvDLLIDPMAGGGTIPIEAALLARNVAPGLLLpEg- 248
WP_011322159 146 RFTLAVDLTG-ESLHRRPYRVCEHDAPLRGTLAYQLLRLADYSAD-DRLVDPMAGSATIPIEAALDATDAVPRPDL-D-- 220
WP_010869937 150 ELIVGIDTTGdIALDKRGYRVFNHPAHLNATIASSLVYLSDWKDD-EMLLDPMCGSGTIPIEGALMKRNIPPGKFReNky 228
WP_013798288 152 ELIIGIDTTGdEGLHRRGYRAYNHPAHLNASIASALVKLSNWKDD-EILLDPMCGSGTILVEAAMIKRNIPPGKFRdD-- 228
WP_068548645 166 TLLLGIELVGlEGMHHRHWRKYSHPAGLKSTLASALLMLANFEAH-HVLWDPMCGSGTIPIEAAHRAINFPPAFFRkDe- 243
WP_119725704 146 KLRVMLNTTG-EALHKRGYRTEAGEAPIKESLAAALVLLSGWKFR-ENFYDFFCGSGTIPIEALMIAKNIAPGLKR-S-- 220
WP_114983139 153 SCQIMLEAGG-DVLQRRGRLVSPKHSVLSPAMAAGLIMLSDWDGE-SPMIDPFANDGVLVLEAARYAKKRTPLFED-Ds- 228
3K0B_A       234 -FVSETWDWXPKQVWADARQEAEDLAnYDq-----PLN-IIGGDIDARLIEIAKQNAVEAGLGDLITFRQLQVADFQTE- 305
ADM28083     242 -AINIKV--LERIHAE-VVEHIKRLC-RDrpnidvDRR-YIGIDINPKFVEGAIINAKNMGVDDITLFISRNALEVIPIi 315
BAJ50996     222 -PSFEKIPVFKSIDSAKIREELLKRE-DPg-----TVE-AIGIDVSPKSLNLALDSLETFGRETGVRFVQGDVFRLVEYv 293
WP_012843871 249 qLALFRLSFLDHTAWRRLRHRAERQV-RPr----sPVP-ILAADRYARNVRGMKANLEAMGVAADVTVCAGRAERMAYLe 322
WP_011322159 221 -PAFTVLPRFDGDRFRRRRAAHTR---REa-----AVD-ITARDNQTQWRECARENREAAGFEDEVDIVAADAREASl-- 288
WP_010869937 229 gFKFIDI--FGYELLDKIKKEIVE---NKn-----IYK-IIGLDKNQKYLDGAKDNAKNAEVLDTIEFICGDATKLHEKf 297
WP_013798288 229 -FAFIKI--FGREALDEIKSQIVE---NKk-----MLK-LYGVEKFKKHISGAVKNAENVGVVDTIKFIEGDATEL-EKi 295
WP_068548645 244 -FSFLRTGVLSEQIWHEVVNEENNQI-RWn----yTPK-IFASDVSPKHLEGAKLNASSALVEGKIIFYHCDFREFph-- 314
WP_119725704 221 -FAFERLGLVQSEVIENEKKLAKNKE-FSg-----EYK-IFASDIDEQLLEIAKKNAKKAGFDGQIMFEKKNFTDYLGK- 291
WP_114983139 229 -LRMKKWRTFRHALWKKMREEVVDQL-RD------DVDwIMGFDSNPDNISRIQFSARAVRLNNNIRLRVSKPNMLNYP- 299
3K0B_A       306 --------DEYGVVVANPPYGERLEDEEAVRQLYREXGIVYKRX--PTWSVYVLTSYELFEEV----YGKKATKKRKLYN 371
ADM28083     316 ksiehefgVQIDLAIFNPPYGHRMK-PGKLFDLYLKLLQILKDSnfR--RAVFITSAIRVTQRvidsISDIVVNKIKIIH 392
BAJ50996     294 -------dREVDKVVCNPPFGVRLRLREP-EKFYTEAFTAIAQAcpH-ASLTVIVNKPVIVLKalekSGYIPLSVRKVLL 364
WP_012843871 323 r-----qpTGRRSIVTNPPYGLRLGDPRRIDRLYHDFARACARHgiA--EVVALTPRRDSWLEaftqAGYRPALVQPVRY 395
WP_011322159 289 ---------DADCVVTNLPFGIRVT--GDLRRLYSEFAERVTDGs--vDRLVALTTKPGLLP-------LSPDEQHDIPY 348
WP_010869937 298 --------NESDVIIANPPYGIRIGSKRSVKKLYDEFLSSAKEImhGSSRLIVITAEDKMFKDaiakNNFEVKEEFNVMF 369
WP_013798288 296 dy----lkDGVDVVITNPPYGIRIGGKKMVRNLYNNFLNSLKKIthDDSRIIIITAEDKILRNaainNNYKIKEEFRVMY 371
WP_068548645 315 -------kDEVDIIVTNPPYGVRLANPQKAEKVLQSLLETFCKSyaS--YLVVIHPDRDKVLSkaqsHSLTLDKAVHAYN 385
WP_119725704 292 --------DLTGTLVSNPPYGERLKSD-NLEAMYNSIDKIFRKN--KNLNGGIISSFLEFDNL----VKRNFYKKRKLYN 356
WP_114983139 300 --------KMTGHIMTAPPVDVNL-------RLLGDFARKTKMSa-GGYKMGLFSSIANLDTV----VGMKPEKNRLLEY 359
3K0B_A       372 GYLRTDLYQY 381
ADM28083     393 GTLPSYIYRI 402
BAJ50996     365 GDLSSYIFHS 374
WP_012843871 396 GRLEAFALRV 405
WP_011322159 349 GRIDASVIVW 358
WP_010869937 370 GGLMTRVFYL 379
WP_013798288 372 GGLDTVVFVL 381
WP_068548645 386 GNLKVWLLKL 395
WP_119725704 357 GGELCYFWKK 366
WP_114983139 360 NGRPFSFMEF 369
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