?cl21562: DDE_Tnp_4 Superfamily (this model, PSSM-Id:419734 is obsolete)
DDE superfamily endonuclease This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. |
Jiyao W et al.(2023). "The conserved domain database in 2023.",