2O70,3O7I


Conserved Protein Domain Family
OHCU_decarbox
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pfam09349: OHCU_decarbox (this model, PSSM-Id:401335 is obsolete and has been replaced by 462765)
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OHCU decarboxylase
The proteins in this family are OHCU decarboxylase - enzymes of the purine catabolism that catalyze the conversion of OHCU into S(+)-allantoin. This is the third step of the conversion of uric acid (a purine derivative) to allantoin. Step one is catalyzed by urate oxidase (pfam01014) and step two is catalyzed by HIUases (pfam00576).
Links
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Statistics
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PSSM-Id: 401335
Aligned: 266 rows
Threshold Bit Score: 98.7375
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2O70_B               7 NALAYEDFVKLFGNVVEKCPLISAAIWSYrPFKDLADIEARISEFIHSLPDSGKEGILRCHPDLAGrdLqSGTLTPESQE 86  zebrafish
jgi:Srot_0394       11 NALEPKSAVSALFECCHCVVLAERLAKAR-PYASRSDLFSLADHELFRVDEETLGQIVASHPGVGS--R---PKSKASEG 84  Segnilipa...
WP_005064897        13 NQMPDTRAVHALYECCGSVTWARKVAATR-PFADHDALFRCADNELFALSEESLNEMLTAYPPLGK--R---PGSVRSHA 86  Terrabact...
AHC27621            11 NALPERKAVHALYECCNSYVLARELVRGR-PYPDHDALFRRADAALFELPESAVDQILDACPDIGR--R---PRSAKSQA 84  Mycolicib...
tigr:MSMEG_6116     13 NALPLRRAVHAVFECCCCVTLATDLAKGR-PYPDHASLFAKADELLFSLGEASMDTILQAYPCVGS--R---PHSEKSRG 86  Mycolicib...
AEV72773            11 NAMPMRRAVHAIYECCYSVPLAADLCRGR-PFTTHDELFRSADALLFGLSEESVDTILQAYPDIGR--R---PGSEKSAA 84  Mycolicib...
jgi:Mvan_5382       12 NALPMRRAVHAVFECCYSVPLAADLARAR-PFDTHDRLFRFADTLLFGLSEESIDSILQAYPDVGK--R---PGSEKSQA 85  Mycolicib...
CeBiTec:CGLY_12770  14 NRMTPTQVADMIGDLLYSPQLGAAIAAAA-PFRSLEHVLDAAHRELLRLPRVEILASIQAHPVLGE--K---TTDSYSRE 87  Corynebac...
WP_014009176        34 NKMSREQISALIGDLLYNPTLGEEIAAAA-PFRSLEHLLDVAHRELLRMPRVEVLTSIQAHPTLGE--Q---TTDIYSRE 107 Corynebac...
CeBiTec:CGLY_01760  18 NRVPTAELVDRVADLFASRTLAAALVDVR-PFATVDALCATASVLFQEQDEAEVLESVNAHPPIGG----VVAAGSLSAA 92  Corynebac...

2O70_B              87 EQSQAGmtTLDSAEIVHMYRLNSEYKERFGFPFVICARLN-NKaDIVRQLSERLKNrRTAELECAIEEVKKICSLRLH 163 zebrafish
jgi:Srot_0394       85 EQCAIW--DQDHAVMSRLHAVVGQYEAHFNRPFLIYAGELsAG-EVIAVAEQRLHNdEETEGKVVRNELAKVHRHRLE 159 Segniliparu...
WP_005064897        87 EQCAIR--DETPGMMAALRAAAHRYEHHFGHRFVMHMCGQdGA-SVLRAISDRMHHdADTERKVTRNELAKINRTRLE 161 Terrabacter...
AHC27621            85 EPCAVW--DDDAELMAALSAASRQYAQRYGFTFVMFVDGHcAR-DVLAAVTDRMHHdIETERKILRNELAKIGRSRLE 159 Mycolicibac...
tigr:MSMEG_6116     87 EQCAVW--DADATVMAQLDEAARRYCERFGFGFVMYVGDScAR-DVLAAMDLRLHNdHETERKVVRNELSRINRARLE 161 Mycolicibac...
AEV72773            85 EQCAIW--CDEPGVMEQLSEASRRYLEHFGFGFVMFVNGYtAQ-DVLAAMSDRLHNdVDTERKIVRNELARINRTRLE 159 Mycolicibac...
jgi:Mvan_5382       86 EQCAIV--DDRPEMMAELAAASKKYLDHFGFGFVMFINGYcAD-DVLASMHDRMHNdYETERKVVRNELARINRTRLE 160 Mycolicibac...
CeBiTec:CGLY_12770  88 EQSFIL--DSPPEVLVEIADLCQRYEARFHHIFLVCAQGIgGH-EVLLLLKRRLENpTVTEWETTVRELGRINVLRLR 162 Corynebacte...
WP_014009176       108 EQSFIL--ESPPEVLAEVADLCRRYEERFHHLFLVCAQGIgGH-EVLRLLRRRLDNpTVTEWETTVRELGRINTLRLR 182 Corynebacte...
CeBiTec:CGLY_01760  93 EQAAATeqATEQGELQAIRNLQPTYRDKFGWNFLIRAAGRdSR-QILDALVERLAHaPEEEWPVVVDNLDAINQLRLR 169 Corynebacte...
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