Conserved Protein Domain Family
PRK00748

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PRK00748: PRK00748 
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Validated
Links
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Statistics
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PSSM-Id: 179108
Aligned: 536 rows
Threshold Bit Score: 280.799
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
134096220   1 MLLIPAIDLKDG------HCVRLKQGDMDQATVFSEDPADMARHWLEQGARRLHLVDLNGAFAGKPKNEPAVKAILQAVR 74 
285018044   3 FLVYPALDIRDG------RVVRLAQGDYARETHYGDDPLRRAKAYADAGAQWMHLVDLDAARAGGYTLGPLLERIRAQTG 76 
15838806    3 FIVYPALDIRNG------AVVRLQQGDYARQTRYDDQVLPRALAFADSGATWMHLVDLDAAKAGGYTLAPLLRQMTRATG 76 
28199149    3 FIVYPALDIRNG------AVVRLQQGDYARQTRYDDQVLPRAQAFADSGATWMHLVDLDAAKAGGYTLAPLLRQITRATG 76 
37524798    7 FEIFPSVDIVDGiamtsnSAIRLTRGESSTLRRPLGTPAEVALAWQNAGAKWIHVVDLDAA-SGRGSNSHLIADVLAAVD 85 
170730535   3 FIVYPALDIRNG------AVVRLQQGDYARQTRYDDQVLPRAQAFADSGATWMHLVDLDAAKAGGYTLAPLLRQITRATG 76 
182681880   3 FIVYPALDIRNG------AVVRLQQGDYARQTRYDDQVLPRAQAFADSGATWMHLVDLDAAKAGGYTLAPLLRQITRATG 76 
190574122   3 FIVYPALDIRDG------RVVRLRQGDYAQETSYGDDALPRAQALAAQGAQWMHLVDLDAARAGGYTLAPLLASIRAQTP 76 
194365538   3 FIVYPALDIRDG------RVVRLRQGDYAQETSYGDDPLPRTQAFAAQGAQWMHLVDLDAARAGGYTLAPLLSSIRAQTT 76 
253988220  11 FEIFPSVDIVDGvamtsnSAIRLTRGESPTLRRPLGTPVEVALAWQNAGAKWIHVVDLDAA-SGRGSNSHLIADVIAAVD 89 
134096220  75 EyaekngieeiPVQLGGGIRDLDTIERYLDDGLSYIIIGTAAVKNPGFLHDACSAF-PGQIIVGLDAK-----DGKVATD 148
285018044  77 L----------HVQTGGGVRSRADVQRMLDAGATRVVIGSLAVRDRESVLEWLAEFgPARITVALDTRqdakkVWRLPVL 146
15838806   77 L----------QVQTGGGVRSRDDVARILDAGAARVVIGSLAVRESARVIEWLQAFgPERITVALDTRqdaggVWRLPVH 146
28199149   77 L----------QVQTGGGVRSRDDVARILDAGAARVVIGSLAVRQMTCVIEWLQAFgPERITVALDTRqdaggVWRLPVH 146
37524798   86 I----------NVQVCGGIRDETILRKVLATGCQRVNLGTAALENPDWCAQAIAEY-GDKIAIALDVKst-seGYQLATH 153
170730535  77 L----------QVQTGGGVRSRDDVVRILDAGAARVVIGSLAVRQMACVIEWLQAFgPERITVALDTRqdaggVWRLPVH 146
182681880  77 L----------QVQTGGGVRSRDDVARILDAGAARVVIGSLAVRQMTCVIEWLQAFgPERITVALDTRqdaggVWRLPVH 146
190574122  77 L----------QVQTGGGVRGRDDVARILDAGAGRVVVGSLAVRRPDEVVGWLEEFgAERITIALDARqdaqgQWQLPVH 146
194365538  77 L----------QVQTGGGVRGRDDVARILDAGAGRVVVGSLAVRRPDEVVGWLEEFgAERITIALDARqdaqgQWQLPVH 146
253988220  90 I----------NVQICGGIRDEVILNRILATGCQRVNLGTAALEKPDWCARAIAEH-GDKIAIALDVKst-seGYQLATH 157
134096220 149 GWSKLSGHEVIDLAKKFEDYGCESIIYTDIGRDGMMGGVNIEATVKLAQSMT-IPVIASGGVHNIKDVEALCAVQEegIE 227
285018044 147 GWTETSSLTLDALAGEYAAAGLTHLLCTDIARDGMLSGPNLALYAHLRQIAPdVAVQASGGVRNAADVRATREVG---CA 223
15838806  147 GWTEVAEATLDVLAQQYAAAGLRHLLCTDIARDGMLSGPNMDVYTYLRALVPaVQLQVSGGARDVADVVAAKMAG---CA 223
28199149  147 GWTEVAEATLEALAQQYAAAGLRHLLCTDIARDGMLSGPNMDVYAYLRALVPaVQIQVSGGARDVADVVAAKMAG---CA 223
37524798  154 GW-NVSKGNLWDLLERLDKQGCQRYVVTDVERGGMMSSPNFTLLQEVCAKTS-SPVIAGGGVSSLDDLRALADLSTigVE 231
170730535 147 GWTEVAEATLDVLAQQYAAAGLRHLLCTDIARDGMLSGPNMDVYTYLRALVPaVQLQVSGGARDVADVVAAKMAG---CA 223
182681880 147 GWTEVAEATLEALAQQYAAAGLRHLLCTDIARDGMLSGPNMDVYAYLRALVPaVQIQVSGGARDVADVVAAKMAG---CA 223
190574122 147 GWTENAGVTLDVLAQRYARAGMRHLLCTDIARDGMLAGPNISLYQHLSALLPgVAVQASGGIRDVADVAEARRAG---CG 223
194365538 147 GWTENADVTLDDLARRYARAGMRHLLCTDIARDGMLAGPNISLYQHLSALLPgVAVQASGGIRDVADVAEARAAG---CG 223
253988220 158 GW-NVSNGNLWDVLERLDKQGCQRYVVTDVERGGMMSSPNFTLLREVCAQTS-SPVIAGGGVSSLNDLRALADMSTlgVE 235
134096220 228 GVICGRSIYEGTLDLRSA 245
285018044 224 GVVLGKSLLEGRLRLDEA 241
15838806  224 GIVLGKALLEGRLALKEA 241
28199149  224 GIVLGKALLEGRLALKEA 241
37524798  232 GAILGQALHIGKVPLEDA 249
170730535 224 GIVLGKALLEGRLALKEA 241
182681880 224 GIVLGKALLEGRLALKEA 241
190574122 224 GAILGKALLEQRMDLAEA 241
194365538 224 GAILGKALLEQRMDLAEA 241
253988220 236 GAILGQALHIGLISLEDA 253
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