Conserved Protein Domain Family
CDF_efflux_DmeF
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NF033827: CDF_efflux_DmeF (this model, PSSM-Id:411398 is obsolete and has been replaced by 468196)
CDF family Co(II)/Ni(II) efflux transporter DmeF
DmeF, a metal efflux transporter belongs to the cation diffusion facilitator (CDF) family. Examples from different species have been described as primarily being induced by, or performing efflux of, different panels of metals, including Co(II) and Ni(II) for Rhizobium leguminosarum and Agrobacterium tumefaciens, and a broader spectrum Wautersia metallidurans CH34.
Links
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Statistics
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PSSM-Id: 411398
Aligned: 182 rows
Threshold Bit Score: 358.73
Created: 20-Oct-2021
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_007182793  12 GHDHIFLGAGHEKNERKTWAVIALCSAMMLIEIVGGSMFGSLALVADGLHMSTHAGAMLIAALAYTYARKHATDSRFVFG 91  Burkholderia sp...
WP_012096813  10 QHDHAFVGREPARAERRTRWVVALTLGMMVAEIVAGTLFRSMALLADGWHMGTHAAALSVAAFAYAYARKHAADPRYTFG 89  Anaeromyxobacte...
WP_012524550  10 KHGHAFGTAVEASGERRTRWVVALTLAMMVGEIAAGMVYGSMALLADGWHMGTHAAALGVAAFAYAYARRHAADPRYSFG 89  Anaeromyxobacte...
WP_017670869  11 THDHVFAGQREAESERRTWYVVALTAVTMVAEIAGGWWTGSMALLADGWHMGSHVAALGLAGFAYHFARTHADDRRFSMG 90  Blastomonas sp....
WP_015280704  10 RHSHDFGNPDQRQAERRTHWVIGLTLAAMALELVAGWLTGSMALLADGWHMGSHAAALGIAAYAYAFARRRGGDPRFTFG 89  Thioflavicoccus...
WP_007192912  10 GHSHDFATADQADAERRTRWVVGLTLAAMCVELVAGWITGSMALLADGWHMGSHAAALGIAAYAYAFARQRGADRRFTFG 89  Thiocapsa marina
WP_016954298  10 QYAHKF-TVDNRGAERKVNMVFALTTVTMVIEIVAGSWYGSMALLADGWHMLTHSAAFAISMFVYWYARKNANNPAFTFG 88  Catenovulum aga...
WP_013051588  12 QHTHNF-SSVSDAGERNTRYVLYLTVVTMVAEITAGTVYGSMALLADGWHMGTHAAAFMITLFAFNYSRKHANNPEFTFG 90  Shewanella viol...
WP_012155564  11 CVDKQKFSTQNSSGERNTFYVLVLTIVTMLAEIIAGTIYGSMALLADGWHMGTHAAAFMITLFAYRYARKHANSAEFSYG 90  Shewanella peal...
WP_012277051  12 ADKHKF-STQNSAGERNTAYVLVLTIVTMLAEIIAGTIYGSMALLADGWHMGTHAAAFLITLFAYRYARKHANSPEFSYG 90  Shewanella hali...

WP_007182793  92 TGKLGDLAGFTSAIVLAMIAVLIGYEAVSRFLSPIPIHFGEAIPIAVVGLLVNLASVWLLS--GDHHgqg--------hs 161 Burkholderia sp...
WP_012096813  90 TGKVGALGGFASAVGLAVIALLVLTESAVRLASPVTIRFDEAILVACVGLAVNLFCAFLLR--DEEH------------- 154 Anaeromyxobacte...
WP_012524550  90 TGKVGALGGFASAVGLAVVALLVLGESAVRLASPVAIRFDQAIGVAVLGLLVNLFSAFLLRdeDHGHahdhgdhedhddh 169 Anaeromyxobacte...
WP_017670869  91 TGKVGSLTAFGSALLLGVIALLMAWESAVRLASPVTIDYSAAIIVTVIGLAVNIASAFMLG--GHDHh------------ 156 Blastomonas sp....
WP_015280704  90 TGKVSSLAGYSSALLLAAGALWMAVESVSRLLDPVPIHYQEAMAVAAFGLAVNLASAWLLGh-HGYD------------- 155 Thioflavicoccus...
WP_007192912  90 TGKVSSLAGYSSALLLATGALWMLVESLSRLIDPVEIRYAEAMIVAAFGLAVNLLSAWLLGhsGDGHh------------ 157 Thiocapsa marina
WP_016954298  89 TGKVNALGGFASAVALGTVAFMMVIESTERLLVPESIQFNQAIAVAILGFIVNLVSAVLLH--DSHGh------------ 154 Catenovulum aga...
WP_013051588  91 TGKVSVLGGFTSAIALGLVAIIMLVESVMRVFSPHEIQFNQAIMVAIIGLTVNVISVFLLK---DHH------------- 154 Shewanella viol...
WP_012155564  91 TGKVSVLGGYTSAIALGLVALVMLVESSVRIFNPHEIYFNQAILVAIIGLIVNVVSVFLLK--DHHSh------------ 156 Shewanella peal...
WP_012277051  91 TGKVSVLGGYTSAIALGLVALVMLIESSVRIFNPHEIYFNQAIVVAIIGLIVNVVSVFLLK--DHHSh------------ 156 Shewanella hali...

WP_007182793 162 hGHSH-GHSHGhshghshgqgrgHGhddhahedevqKIFARSGVFAvsifedsvppvfritpetegsrldaatvsvttvr 240 Burkholderia sp...
WP_012096813 155 -GHAH-GTDHLd----------aHD------------GREDHDHDHv--------------------------------- 177 Anaeromyxobacte...
WP_012524550 170 pAHDHgAHGHA------------HNdh--------dHDEHGHAHRD---------------------------------- 195 Anaeromyxobacte...
WP_017670869 157 -HHDH-DAAHDh-----------HG---------------DHDHHD---------------------------------- 174 Blastomonas sp....
WP_015280704 156 -HHDH-GHGHG------------HAd---------dHRDDGQGHDHq--------------------------------- 179 Thioflavicoccus...
WP_007192912 158 -HHGH-RHAHE------------HDhe-------rvHGHDDHAHD----------------------------------- 181 Thiocapsa marina
WP_016954298 155 -DHGH-SHHHHsq--------hnHG-----------HSHDDHQHSH---------------------------------- 179 Catenovulum aga...
WP_013051588 155 -THDH-SHGHS------------HSh----------SHDHSHSNSH---------------------------------- 176 Shewanella viol...
WP_012155564 157 -DHGN-EHGHK------------HGhn--------hEHSHEHKHSH---------------------------------- 180 Shewanella peal...
WP_012277051 157 -DHGHsHSHHD------------HDvhkgv-iqdekYHDHNHGYHE---------------------------------- 188 Shewanella hali...

WP_007182793 241 pdgarqvfamahrggyleskdeipephafraivrlsdgdhevefaeH---EHGHdthe---avsRDHNIRSAYMHVMADA 314 Burkholderia sp...
WP_012096813 178 ----------------------------------------------Hr--GHGHr----------DHNLRAAYLHVLADA 199 Anaeromyxobacte...
WP_012524550 196 ----------------------------------------------HdhdAHAHavhapghdehRDHNLRAAYLHVLADA 229 Anaeromyxobacte...
WP_017670869 175 ----------------------------------------------Hg--DHHH-----------DHNLRAAYVHVLTDA 195 Blastomonas sp....
WP_015280704 180 --------------------------------------------------THGRl---------QDHNLKAAYLHVLADA 200 Thioflavicoccus...
WP_007192912 182 ----------------------------------------------HgrhDHRHgla-----diQDHNLKAAYLHVIADA 210 Thiocapsa marina
WP_016954298 180 ----------------------------------------------Eh--SHAH-----------DHNLAAAYFHVLADM 200 Catenovulum aga...
WP_013051588 177 ----------------------------------------------VaedAHEQt---------HDHNLKAAYFHVLADA 201 Shewanella viol...
WP_012155564 181 --------------------------------------------------HHGQ-----------DHNLRAAYFHVLADA 199 Shewanella peal...
WP_012277051 189 ----------------------------------------------HsdgEKHHg---------QDHNLRAAYFHVLADA 213 Shewanella hali...

WP_007182793 315 AVSVLAIAGLVLARAFGWLWMDPLAGIIGALVIANWSYGLMRDTGAILLDINPDRRMTENVRHAIEDRG-D-KVVDLHVW 392 Burkholderia sp...
WP_012096813 200 MTSVLAIVALLAGRTLGWSWMDPVMGIVGSVVIARWSYGLLRDTSSVLLDAEASAARRAEIRGALEQGG-D-RVADLHVW 277 Anaeromyxobacte...
WP_012524550 230 LTSVLAIVALLAGRVLGWTWMDPVMGIVGALVIARWSVGLLRDTGAVLLDAEVAEGRRAAIRAALEQGE-D-RVADLHLW 307 Anaeromyxobacte...
WP_017670869 196 LTSVLALAALLGGLWLGLAWLDPVMGIIGAVVILWWAAGLMRQSARVLLDMEANPATASAIRQRIEADA-DnRVVDLHLW 274 Blastomonas sp....
WP_015280704 201 LTSVLALVALGLGFAYGWSFLDPLMGIAGALLVGRWAFGLARESAQVLVDAGNHDKIASEIREAIECDS-DtRIADLHIW 279 Thioflavicoccus...
WP_007192912 211 LTSVLALAALAMGMLYGWAFMDPLMGIVGAVLVGRWAWGLARESAQVLLDAGDNSAIEHEIRRRIEADA-DnQVADLHVW 289 Thiocapsa marina
WP_016954298 201 LTSVLAIVALILGKYYNWLWADALMGIIGSVVIAKWAYHLMVNSSHILLDKTEHDDLAIQAQQIIEQQG-S-QVTDLHVW 278 Catenovulum aga...
WP_013051588 202 LTSILAIGALLLGKLYGLNWLDPIMGIVGSIIITRWAWQLLKQTAPILLDASIENDYKQEIVQAIESDTqD-EVSDIHVW 280 Shewanella viol...
WP_012155564 200 LTSLLAIAALLMGKYFGLTWLDPIMGIVGAVIITRWAWGLLKQTGPVLLDASIEQSYMQQIRQTIEQES-A-QLVDLHIW 277 Shewanella peal...
WP_012277051 214 LTSLLAIAALLMGKYFGLTWLDPIMGIVGAVIITRWAWGLLKQTGPVLLDASIEQSYMQQIKQTIEQES-A-QLVDLHIW 291 Shewanella hali...

WP_007182793 393 RVGPGHMSAVVSVsTNEPQRDSRFYHAVLERFKGLSHVTVEVQ 435 Burkholderia sp. Ch1-1
WP_012096813 278 RVGPRHLGAIVSV-VSDAPRPPAAYKQRLAAFPDLVHVTVEVH 319 Anaeromyxobacter sp. Fw109-5
WP_012524550 308 RVGPRHLAAIVSV-VSTAPRAPAEYKERLHAFPDLVHLTIEVH 349 Anaeromyxobacter sp. K
WP_017670869 275 QVGTGHLALIVSL-ATHNPRPPGHYRALLGDIANLSHCTFEII 316 Blastomonas sp. AAP53
WP_015280704 280 RIAPAGHACIVSL-VTHQPKPIELYRERLAGLPGLLHVTVEVN 321 Thioflavicoccus mobilis
WP_007192912 290 RIAPAGRACILSL-VTHHPRPVEHYRDLLSGMTGLLHITVEVN 331 Thiocapsa marina
WP_016954298 279 KLSSQHTAMIIAI-SSAQPTSPEEYKQLLQQQLHIDHITVEVN 320 Catenovulum agarivorans
WP_013051588 281 RISADHYAAEIAI-VTRVPEETDFYREKLSQFTRLNHLTIEVN 322 Shewanella violacea
WP_012155564 278 KISADHYAASMII-HCERTEKAGYFKEKLSQFERLSHITIEVN 319 Shewanella pealeana
WP_012277051 292 KISADHYAASMII-HCDRVEKSGYFKEKLSQFERLAHITIEVN 333 Shewanella halifaxensis
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