Conserved Protein Domain Family
DUF676

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pfam05057: DUF676 
Putative serine esterase (DUF676)
This family of proteins are probably serine esterase type enzymes with an alpha/beta hydrolase fold.
Statistics
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PSSM-Id: 309968
Aligned: 14 rows
Threshold Bit Score: 87.1605
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q8RWD3      97 KNEPDHLLVLVHGILAS----------PSDW--------LYVEAELKR------RLGRR--FLIYASSSNTFTKTFGGID 150  thale cress
Q12103     189 MSQKSHLVILTHGFQSNv---------SADM--------EYLMEEIYKaq---mNNPNE--RLVIKGYMKNACETEKGIK 246  Saccharomyces ce...
P53118     184 PQKKKHLVVLTHGLHSNv---------STDL--------VYIMEQIYKaq---kNYPHE--QIVVKGYRGNVCQTEKGVK 241  Saccharomyces ce...
O14162     301 HSKNSHLVVLTHGMHSNv---------GADM--------EYLKEKLIEs----sKSVKE--LVVVRGFTGNYCQTEKGVR 357  Schizosaccharomy...
Q04093     192 PEKPVHLVIMTHGIFSNi---------GCDM--------LYMKDKIEEmtfpmdESINP--NIIVRGFMGNVGKSGHGIH 252  Saccharomyces ce...
XP_960700    8 NIEADHLCVLVHGLWGN----------PNHM--------ASVAKALRA------QYPRDk-LNILVAKRNAGSFTYDGIE 62  
Q08448       2 TSDK-HLFVLIHGLWGN----------YTHM--------ESMRTILSTtlk-keDVNDD--MIYFLPKQNAMFKTFDGIE 59   Saccharomyces ce...
O01731     621 SKNKTHLVVFVHGLEGS----------QEDLvpfrcgldQAIAAHYHCiqmegrDFDEEpwAFEYLMSSANRSQTWADIT 690  Caenorhabditis e...
O80590     518 R--ELKIVVFVHGFQASiflmfsecghHLDL--------RLIRNQWLLid----------pKIEFLMSEANEERTHGDFR 577  thale cress
Q6NS59    1236 E-DGVHLIVCVHGLDGN----------SADL--------RLVKTYIEL------GLPGG--RVDFLMSERNQNDTFADFD 1288 house mouse
Q8RWD3     151 GAGKRLAEEVRQVVQKSKSL---------KKISFLAHSLGGLFSRHAVAVLYSAAMaqvsdvavsQsgnsnlLRGRIAGL 221  thale cress
Q12103     247 FLGVGLANYIIDELYDDSVG----------KISFIGHSLGGLTQTFAICYIK-------------Tk-----YPYFFKKV 298  Saccharomyces ce...
P53118     242 YLGTRLAEYIIQDLYDESIR----------KISFVGHSLGGLIQAFAIAYIY-------------Ev-----YPWFFKKV 293  Saccharomyces ce...
O14162     358 WLGKRLGEWLLDITGWGSASfp-----rySHISVVAHSLGGLVQTYAVGYVHAKTHg-----------------AFFQAI 415  Schizosaccharomy...
Q04093     253 CLGVRVGKYVLETVDKLNKKyk------vdRISFIGHSLGGPTQSMAVRYISIKR----------Pd-----FFDAVKGV 311  Saccharomyces ce...
XP_960700   63 LGGERVCNEIEEELQAVESKgg-----kiKKISIAGYSLGGLVARYAIGLLYAR--------------------GVLDNL 117 
Q08448      60 IIGYRTLIEVCEFIRDYKDGki-------tKLSVMGYSQGGLVARFMIGKML-------------Te-----FKELFEDI 114  Saccharomyces ce...
O01731     691 TMAHNLLSEVREYVEEARNDi--------QRISFLAHSLGGVIVRSAVGLAPEVEMq-------wM------ID------ 743  Caenorhabditis e...
O80590     578 EMGQRLAQEVVSFFKRKKDKharygrlknIKLSFVGHSIGNVIIRAAIA---DSLMd-------pY------RK------ 635  thale cress
Q6NS59    1289 CMTDRLLDEIIQYIQIYSLTv--------SKISFIGHSLGNLIIRSVLTRPRFKYY---------L-------S------ 1338 house mouse
Q8RWD3     222 EPINFITLATPHLGVRGRKQLpFLLGVPILEKLAAPIAPFFVGRTGSQLFLT--------------DGKADKPPLLLRMA 287  thale cress
Q12103     299 EPINFISLASPLLGIATSTPN----------YVKMSLSMGIIGTTGQELGLK--------------DGNYGDKPLLYLL- 353  Saccharomyces ce...
P53118     294 NPINFITLASPLLGIVTDNPA----------YIKVLLSFGVIGKTGQDLGLE--------------NDVEVGKPLLYLL- 348  Saccharomyces ce...
O14162     416 HPVFFVTLATPWLGVAGEHPS----------YIGKALSYGIIGKTGQDLSLT--------------PLNHSIESRPFLVL 471  Schizosaccharomy...
Q04093     312 KPVNFITLASPFIGVIGDFPF----------YLSVPLDMGALGLTGRDLNLKytpltskdglyaddEVYPEHSKYILEIL 381  Saccharomyces ce...
XP_960700  118 ECMTFTAFASPFLGVRTPLRG-------WPNHVWNVLGARTLCMSGRQLFGI--------------DHFRDTGKPLLAVL 176 
Q08448     115 EPQLFITMATPHLGVEFYNPTgIAYKSALYSALRT-LGSTILGKSGREMFIA-----------------NSSNNILVKLS 176  Saccharomyces ce...
O01731     744 RCYTLMTINSPHLGLAYVQKH-IHWGVQFVKWWKKSRSMEQLSFR---------------------DSVDFASSFVYKT- 800  Caenorhabditis e...
O80590     636 YFHTYISLSGPHLGYLYSSNSlFNSGLWLLKKLKSTQVIHQLTLT---------------------DDPDLQNTFFYKLC 694  thale cress
Q6NS59    1339 KLHTFLSLSGPHLGTLYNSSAlVNTGLWFMQKWKKSGSLLQLTCR---------------------DHSDPRQTFLYKLS 1397 house mouse
Q8RWD3     288 SDGEDLKFLSA-------LGAF-------------RSRIIYANV---------------SYD 314  thale cress
Q12103     354 ---SEESLISV-------LARF-------------KRRTLYANAvndgi-----vplysSSL 387  Saccharomyces cerevisiae S288C
P53118     349 ---SGLPLIEI-------LRRF-------------KRRTVYANAindgi-----vplytASL 382  Saccharomyces cerevisiae S288C
O14162     472 MSDPSTPFFQA-------VSFF-------------EKRILFANTtndyivpfgtsamevSSL 513  Schizosaccharomyces pombe 972h-
Q04093     382 PQAPAKKVFES----------F-------------KRRTIYANVmddgi-----vplrtAAL 415  Saccharomyces cerevisiae S288C
XP_960700  177 ADPKSIFMCG--------LAKF-------------KRRILYTNIvndrs-----avyytTGI 212 
Q08448     177 QGE----YLEA-------LSLF-------------KWRIAFANVkndrtvafytafitdCDP 214  Saccharomyces cerevisiae S288C
O01731     801 ---S---LNNA-------CGKF-------------KNILLVG-TphdqlvpymssllvpSKI 835  Caenorhabditis elegans
O80590     695 KVEKDVNISSRsctivtnRPLFfgsemlvlklfsaKDVVQFQeynspvf---asariesCQP 753  thale cress
Q6NS59    1398 NKAG--------------LHYF-------------KNVVLVGSLqdryvpy-hsariemCKT 1431 house mouse
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