Conserved Protein Domain Family
SbnI_like_N

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cd16388: SbnI_like_N 
N-terminal domain of transcriptional regulators similar to SbnI
Siderophore staphylobactin biosynthesis protein SbnI of Staphylococcus aureus is a ParB/Spo0J like protein required for the expression of genes in the sbn operon, which is responsible for staphyloferrin B (SB) biosynthesis. SnbI forms dimers and binds DNA upstream of sdnD. SbnI binds heme, which inhibits DNA binding of SbnI, leading to a suppression of sbn operon expression.
Statistics
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PSSM-Id: 319247
Aligned: 40 rows
Threshold Bit Score: 96.0347
Created: 7-Mar-2016
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative active
Feature 1:putative active site [active site]
Evidence:
  • Comment:Putative active site residues by comparison to ParB N-terminal domain-containing superfamily proteins such as Osa and Srx

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                          #                               #  ##                      
CDR59602       8 LKLVPVDKIDLHEtFEPLRLEKTKSSIEADGFIRHPILVTPMqhGRYMVIDGVHRYTSLKELGCKKVPVQEIHETQY 84  Staphylococcus arg...
ELK41388       8 IQVVDSDQVCLHEdHEPNRLDDTCQSISQQGMLLHPPIARRMqdGRYLILDGAHRTAALQKIGCRRIPVQVVTDADY 84  Brevibacillus agri...
KEO82628       1 MQVVNLDRIRFHEeYEPHRLDVTCYAIRMEGVLRHPPIAMQMrdGSYVILDGAHRTHALEALGCKRAVLQVVKPEQF 77  Tumebacillus sp. NFB
EMT52600       8 LQLIELDKMSLHEeHEPSRLERVSQSMREDGFLRHPILATEMrdGRYLVLDGAHRIGALRLLGYCKVPVQVARQDDF 84  Brevibacillus bors...
AMA71824       8 LRLIDIKKICLHEeHEHTRLAQTCAAISTDGVLRHPPLAMQMsdGRYLILDGAHRTNALQNLGCKRIAVQIIEREEI 84  Aneurinibacillus s...
WP_041098717   7 LQIINIDAICLHEdHEPQRLDKTCKAIQQSGELCHPPIAMQMrdGRYLILDGAHRTGALQRMGCKRIPVQLARAEDI 83  Bacillus badius
WP_053366313   8 LKLLPIDLVDLHEdYEPSRLGKIISSIENDQFLRHPIIVTRLsnNRYLVLDGVHRFTSLKKLGCTNVPVQEVGKDEF 84  Bacillus sp. FJAT-...
WP_031415179   8 LQLLDREMICFHEeYEPNRLNQTTLAIEREGLLRHPPLAMKLhdGRYVILDGAHRVHALQKLGCKRVVVQLVNPKNI 84  Brevibacillus late...
WP_022738323   7 LERIPIQNLHLHEaHEPGRLQKTCDSIRQEGMLRHPILATPMd-GGYLVLDGAHRLASLRRLGCVYAPVQIIEREHL 82  Thermoactinomyces ...
WP_003343532   7 LRVVDIDQICFHEaHEEARLLHTCQLIQNEGVLRHTPLASQLndGRYLILDGAHRTLALKKLQCCRVVVQMVHLDNC 83  Brevibacillus late...

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