HdrA2 represents a distinct subclass of the HdrA family, which is the A subunit of the CoB-CoM heterodisulfide reductase. HdrA2 from Methanosarcina acetivorans. A distinctive feature is a MvhD-like C-terminal domain, where MvhD is the signature delta subunit of the F420-non-reducing type of hydrogenase, Mvh.
Jiyao W et al.(2023). "The conserved domain database in 2023.",