6MQH,3QZE


Conserved Protein Domain Family
DapA

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COG0329: DapA 
4-hydroxy-tetrahydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism, Cell wall/membrane/envelope biogenesis]
4-hydroxy-tetrahydrodipicolinate synthase/N-acetylneuraminate lyase is part of the Pathway/BioSystem: Lysine biosynthesis
Statistics
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PSSM-Id: 440098
Aligned: 882 rows
Threshold Bit Score: 61.3225
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6MQH_A        18 QI-R-----GSVPAIVTPM----LEDG-GLDLAAFRKLIDWHI-E----EGTDALVVVGTSGEsaTLSVDEHVLMIETAV 81 
WP_086091712   8 tIgH-----RRYVAVLLPF----DKSF-KIDEQAYRRYVRYFA-DdprfAREGGLCINPEAGEifYLSREEKRRVLEIAM 76 
WP_083269733  14 RL-R-----GIHAATIVPM----KPDF-SIDEAALAQHVASVT-Av---PGINGLLVNGHAGEnfVLSLAEKRRVVEIAR 78 
WP_075800432   7 GI-G-----GVWPASLTPFapngTPDG-AIDEASLRGHLAQLA-Gt---PGVRALVVNGHAGEatSLDRAERRQVVQIAR 75 
WP_069689341   9 PF-S-----GLISAPFMPM----LPDG-AIDWASLRRYTDWIV-S----QKPDAVAVNMDAAEgpALTAEERVEVMRVCA 72 
WP_012171209   8 RL-S-----GIHAATVVPM----RADF-SMDEDALAAHIGAVT-Rv---KGIRGLLINGHAGEnfVLSLAEKRRVVEIAR 72 
WP_071479428   6 SY-TtattwGIHAATVCPM----LPDG-RIDKDALAAHLRDICmT----PGISGLLLNGHAGEgaFLTLEERAEVIVTAR 75 
WP_075800436   5 RF-R-----GLYASIICPM----HPDG-ALDAPGLEAHARQVL-Ac---PGLGGLLVNGHAGEnvLLEREEARQVVRIAR 69 
WP_041946079   7 GV-G-----GIWPATLTPF----TPDG-RVDDDALAAHVRDVA-Gt---PGVRAVVVNGHAGEatSLDRAERTQVVRVAV 71 
WP_095847051   6 PF-H-----GVYAATLCPM----DATGrNIDEESLATHMQEIS-Qv---EGIRGLLINGHAGEnfALTRAEKRRVVDIAR 71 
6MQH_A        82 KHAakRIPIVAGAGGNsTTEAIELSKHAKAVGADATLQVVP-------------YYN----KP----TQEGIYRHFKAIA 140
WP_086091712  77 EEAhgKLPIIAGTWALtTDETVATARDCKALGVDGIFVTPPggaqdvtscwdadGY------P------EIWLDQIIAQD 144
WP_083269733  79 EHGprECLIVSGVNHEsSLEAAREAAVLEEAGADGLLVFPP-------------NSW----ALg--hADACVIEHHERVR 139
WP_075800432  76 QVAsgRVGVVAGIVAEdTRGACTLARDAAEAGADALLLFPP-------------LLF----AQgaamRPEMVLRFVKAVA 138
WP_069689341  73 EVNagRVPLLSGLIGGsTEAMIAHGRDLLAAGAEGFCVFPP-------------MPVfigsPI----PAEMIRRFHGDIA 135
WP_012171209  73 TVApkDCLLVSGVNHEsSLEAAREAAEMAAAGADGLLVFPP-------------NSW----ALg--hADACTLMHHKMIA 133
WP_071479428  76 AQSaeGCFITAGVTAEsTNMAVEEARVSKQAGADALLIFPP-------------NHW----AGg--vDAQIVCEHHGTIA 136
WP_075800436  70 R-AagDALIVAGVAAEsSAAAARLARDAAEEGADAIMIFAP-------------FSW----APg--vDPRVVLAHHRAVH 129
WP_041946079  72 A-AagEVPVVAGVVADdTRQACALARDAAQAGASALLLFPP-------------AVF----AQgagaRPDMAHRFVSEVA 133
WP_095847051  72 QVCpaHSILIAGINAEdSFDAQAQADDAKQAGANALLLFPP-------------YSW----TLs--tDAATVLNHHRITN 132
6MQH_A       141 EAvdLPVILYNVPGRT-----V-ADMSNETTLRLA-QVPGIIGVKDATG-NIDR-AAQ---LIKAAPAHFSIYSGDDPTA 208
WP_086091712 145 RAvdLPIVTHPVGGAKppfypG---LPLAATLRICrEVKNVVGWKMTYMyDgfRiIAK---ELRGLDRPVAVMGALASRF 218
WP_083269733 140 DAtsAPLMLYGAPVGA-----GaMAYSPAVLGHLV-ADPRFLAIKEGSW-EVAA-YEEnlrLIQKLRPDFSVLGSGDEHL 211
WP_075800432 139 EAtpLPIVLFQLSMAS-----G-LGYSTDLLLQLCrEVPSIIAVKEGSD-IPAT-YEAnlhALRGLGRPVTVLTTNNGWL 210
WP_069689341 136 QAlrVPLIAFQFPRGW-----G-PDYSGDMLTALA-SIDEVIAIKESSF-DANQ-TIQaveSISRLERPIGILTGSDTFI 206
WP_012171209 134 DAtaLPLMLYGAPVGA-----GaMSYSSEVLSRLI-DDPRFVAIKDGSW-EVAA-YEEnlrLIQSRRPGFAVLGSGDEHL 205
WP_071479428 137 RAvdLPIVLYKAPVTA-----GpISYSDEVMTALLmKIEQIIAIKEGSW-EVAA-YEQtwrLAGRLRPDVSVLGSGDEHL 209
WP_075800436 130 DAttLPLFLFQGSVRS-----GgLFFPPEVLAELF-RLPRAVAIKEGSW-EADA-YDTtrrLAARLRPELAVMASGDEHL 201
WP_041946079 134 AAssLPIVLFQLSRAS-----G-LAYSTDTLAQLCtDVPAIVAVKEGSD-IPEF-YEDnlrALRALPRPVTLLSSSNSWL 205
WP_095847051 133 ANaqMPMMLYQSGVGT-----GgMAYTPDILRALV-QLPNIVAVKEGSW-ETAA-YDAnrrLMQHIAPHVAVMASGDEHL 204
6MQH_A       209 IALMLLG-GHGNISVTANVAPRAMSELCRAALAADVKTAREIHMK-LLSLHKHLFIE--A---NPiPV--KWALQQMG-K 278
WP_086091712 219 HEYKATGmFDGTLSGFWTFAKEPMLDHLDAWDARDIDKACAIWNGgLCELHEYI-ADm-Gr-lH---IryKTATWLRGlI 292
WP_083269733 212 LTSYIIG-SAGSQVSLAAVVPELVVALWNAAEAGDWTRARAVHEK-LYPLSVAVYRDapGg-rATaRL--KACLKLLGrL 286
WP_075800432 211 MASLAYG-GDGILSGIGSVAPGLLAELFAASQRGDVATARRVQER-LLPLTRVFYRRp-Gl-dMHnRM--KTALHLLGlL 284
WP_069689341 207 YEAMLMG-CGGALIGFAGTAVAELVDMQRAHRAGDTAKGFAIWSR-LAPLARYCWRp--PirdFRpRM--KELLVMQGvI 280
WP_012171209 206 LTSYVIG-SAGSQVSLAAVVPELVVALWDAAAAGDWARARQVHEQ-LYPLSVAIYRDapGg-rATaRL--KTCLKLLGrL 280
WP_071479428 210 LTSYLIG-SRGSQVSLAAIIPRTIVALHDAVMKQDWQEARAQHEA-LYALSVAIYRDrpAy-lATaRL--KATLKLLGrI 284
WP_075800436 202 FACFALG-SAGSLVSLAAVVPELVVALDEAVRRHDLPAARALHER-LAPLARAIYGTapPg-lATpRL--KACLHLLGrL 276
WP_041946079 206 FASLAYG-ADGILSGLGSVAAGLLVALHEAVARGDLAAARAVNER-LVPLCRAFYRAp-Yl-dAHnRM--KTALHLLGrL 279
WP_095847051 205 FTCFALG-TDGSLVSLAAVIPDLVVALYRAVQAMDLGEARRLHEY-IYPLAKAIYGTqpGt-hANaRL--KACLHMLGrF 279
6MQH_A       279 iAGgiRLPLtP-LDERCHETVRGALREAG--L 307
WP_086091712 293 pNPfmRAPM-PkPKQEEIDTIYRLLKNLNldV 323
WP_083269733 287 pNDvlRPPQpS-VTADELRTLAAALQIAG--Y 315
WP_075800432 285 pHPdpRPPLlP-ITPAEREEIRQALLASG--L 313
WP_069689341 281 dHAavRRPQlG-ISSEEREVIARLGREAG--L 309
WP_012171209 281 gNDvvRPPQpS-CDARENAALSAALRAAG--V 309
WP_071479428 285 pHDtvRRPMrQ-LSTIEYRRLMDAIDVST--I 313
WP_075800436 277 sSPacRAPLpA-LGEAEYDALREALGQAG--M 305
WP_041946079 280 pHPdpRPPLlP-VPADDTARIRAALLASG--L 308
WP_095847051 280 pCAttRAPIpP-LDRAQYQHLEAALAHAG--A 308
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