Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins
Escherichia coli Wzx and related proteins from other gram-negative bacteria are thought to act as flippases, assisting in the membrane translocation of lipopolysaccharides including those containing O-antigens. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Jiyao W et al.(2023). "The conserved domain database in 2023.",