Conserved Protein Domain Family
pyrE

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PRK00455: pyrE 
orotate phosphoribosyltransferase; Validated
Statistics
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PSSM-Id: 234771
Aligned: 808 rows
Threshold Bit Score: 147.611
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
93006858   10 APFSSHAFIQLALDNQVLKFGEFVLKSGRISPYFFNAG-LLASGEMLSLLARGYADALAEqmaatnegkgaqEL-VIFGA 87 
226357001   1 -----MDVLELYQQAGAYHEGHFLLASGRHSPKFLQSTtLLQYPHLTEQIGQALAARLQGeg---------iQAdFLIGP 66 
94984246    9 CDTRRMDVLALYQQAGAYHEGHFLLASGRHSPKFLQSTtVLQYPHLTEKIGQALAERLREag---------iQAdLLVGP 79 
15805474    1 --MSQTDVLDLYKQAGAFHEGRFLLASGRQSPYFMQSTtLLQHPRALMELGGLMSQKILDag---------lKPdFIVGP 69 
57234064    1 ----MEDVETLFEKTGAILKGHFLLTSGLHSPIYWEKFrIIENPEYNQQLCGMIAEHYKDk-----------GIeLVAGP 65 
73748883    1 ----MEDVVTLFEKTGAILKGHFLLTSGLHSPIYWEKFrIIENPEYNQQLCSMIADHYKDk-----------GIeLVAGP 65 
147669644   1 ----MEDVVTLFEKTGAILKGHFLLTSGLHSPIYWEKFrIIENPEYNQQLCSMIADHYKDk-----------GIeLVAGP 65 
270308364   1 ----MEDVETLFEKTGAILKGHFLLTSGLHSPIYWEKFrIIENPEYNQQLCGMIAEHYKDk-----------GIeLVAGP 65 
289432879   1 ----MEDVETLFEKTGAILKGHFLLTSGLHSPIYWEKFrIIENPEYNQQLCSMIADHYKDk-----------GIeLVAGP 65 
297623687   1 -MLHLMDVLDLYKQTGAYLEGHFLLASGRHSPKFLQSTtVMQYPEHAEALGAALAEKFRDl-----------ELdFVLGP 68 
93006858   88 AYKGIPFVAATAQALwlhhgiN-ANWGYNRK-EAKTHG-EGGNLVGADVS----GKAVWVLDDVITAGTAMREVVEILKQ 160
226357001  67 AMGGVTLAYETARHYdngkgpSgRRAIFAEK-D------GQGGMKIREAFtitpGETFVAVEDVLTTGGSVLKAVRAAEQ 139
94984246   80 AMGGVILAYEVARHY------G-TRAIFTEK-DGKGGMkVREAFSLAP------GETFVAVEDVLTTGGSVLKAVRAVEA 145
15805474   70 AMGGVTLAYEVARQLset-lpD-VRAIFAEK-D------GSGGMKLREAFavrpGETFVAVEDVLTTGGSLLRAVRAVEG 140
57234064   66 TTGGIVLAHEIARQM------G-LKCVFAEKiADSERGfRRGFVIKP-------GAKVLVVDDILTTGKSVREVLAAVKK 131
73748883   66 TTGGIVLAHEIARQM------G-LKCVFAEKiADSERGfRRGFVIKP-------GAKILVVDDILTTGKSIREVLAAVKK 131
147669644  66 TTGGIVLAHEIARQM------G-LKCVFAEKiADSERGfRRGFVIKP-------GAKILVVDDILTTGKSIREVLAAVKK 131
270308364  66 TTGGIVLAHEIARQM------G-LKCVFAEKiADSERGfRRGFVIKP-------GAKVLVVDDILTTGKSVREVLAAVKK 131
289432879  66 TTGGIVLAHEIARQM------G-LKCVFAEKiADSERGfRRGFVIKP-------GAKILVVDDILTTGKSIREVLAAVKK 131
297623687  69 AMGGVILAHTVAKAL------G-CRALFAEK--------AGKGMILRDAFkvtpGERFLAVEDVITTGGSLRKAIRAAEA 133
93006858  161 AGAHVAGIIVALDRkekg----------laerSAIQELAATLNVPVRALVDIDDLISYLAeggHSNQNATQLAKMQHYRG 230
226357001 140 AGGRCVAIACIVDR-----------------------RAQEGPLEGYRLVSLTRLVFDTY----------LPDEVPGWLA 186
94984246  146 LGGKCVAVACIVDR--------------------REEAGPLEGYPLISLTRLTFETYAPDe-vPAWLAARPLQKI----- 199
15805474  141 QGGQCIGLCCIIDR-----------------------RQQTGPLSGYPLMSLKELYFDTY----------ASHEVPGWLA 187
57234064  132 AGGEVAGIGVLVDR---------------------SDTALQFNAPVFSCLRSATTTYKPE---DCPLCRQGLPLTKHGSS 187
73748883  132 AGGEVAGIGVLVDR---------------------SDTALEFNAPVFSCLRSATTTYKPD---DCPLCQEGLPLTKHGSS 187
147669644 132 AGGEVAGIGVLVDR---------------------SDTALEFNAPVFSCLRSATTTYKPD---DCPLCQEGLPLTKHGSS 187
270308364 132 AGGEVAGIGVLVDR---------------------SDTALEFNAPVFSCLRSATTTYKPD---DCPLCRQGLPLTKHGSS 187
289432879 132 AGGEVAGIGVLVDR---------------------SDTALEFNAPVFSCLRSATTTYKPD---DCPLCQEGLPLTKHGSS 187
297623687 134 EGARCVDIGCIIDRlgsplaprslvqlefpsyAPDACPLCRAGVPLEEV------------------------------- 182
93006858  231 QYGV 234
226357001 187 EIPL 190
94984246      ----    
15805474  188 ERPL 191
57234064      ----    
73748883      ----    
147669644     ----    
270308364     ----    
289432879     ----    
297623687     ----    
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