Conserved Protein Domain Family
Collectrin

?
pfam16959: Collectrin (this model, PSSM-Id:407175 is obsolete and has been replaced by 465322)
Renal amino acid transporter
Collectrin is a single-pass transmembrane protein that is homologous to the C-terminal region of human angiotensin-converting enzyme 2, ACE2, found in Peptidase_M2 pfam01401. Collectrin is critical for normal amino acid reabsorption in the kidney.
Statistics
?
PSSM-Id: 407175
Aligned: 39 rows
Threshold Bit Score: 190.519
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
XP_002719891 617 SIKVRISLKTALGDQAYEWNDSEMY-LFRSSVAYAMRKYFSEVKNQTILFGEEDVRVSDLKPRISFNFFVTAPNNVNDII 695 rabbit
NP_001132930  38 GFKVRISLKTALGNDAYEWNESEKF-LFRSTLAYAMRKKTGEDT-----YNIENILVCNDTKRVSFIFVVTLPADPTQLI 111 zebrafish
XP_005997909  27 AYKVRLSIKTALGDKAYNWNENEQY-LFRATIAFAMRQYLKNEI-----FRASNVLTCNETQRVSFWFVVTSPENPSVTI 100 coelacanth
AAI61778      32 AFKVRLNIKAALGDNAYTWNADEEY-LFKAVMAFVMRSYTKNNT-----FDISNIVLCNSTERISFWFVVTSPSNESDPV 105 tropical clawed...
2_pfamImport   1 AFKVRLSIRTALGDKAYAWDTNEEY-LFKAMVAFSMRKVPNRETTEVSHFCLF-------FQRNSTWVVRGSPPTPH--- 69 
XP_001515621  63 AFKVRFSIKTALGDNAYAWDSNEEY-LFKAMVAFSMRKYPNRGK-----TEVSNVLLCNITERVSFWFVVTDPSNN-QTI 135 platypus
XP_007500934  27 AFKVRLSLKTALGDKAYTWNENEEY-LFKAMVAFSIRTFSSREK-----IEISNVLLCNVTKRVSFWFVVTDPSEN-QTV 99  gray short-tail...
XP_014584253   7 AFKVRLSIRTALGDKAYAWDTNEEY-LFKAMVAFSMRKVANREK-----TEISHVLLCNVTQRVSFWFVVTDPSEKH-TL 79  horse
3_pfamImport   1 AFKVRLSIRTALGDKAVSGEPAKEYrINKVVFLWSVKISPNRRT-----RKISHVLLCNITQRVSFWFVVTDPTKN-YTL 74 
XP_003218941  27 AFKVRLSIKTALGDNAYSWDATEEY-LFKAVVAFAMRRSFSQEA-----TQVSNVLLCNVTERVSFWFVVTDSSTNKTTV 100 green anole
XP_002719891 696 PRNEVEEAI--SMSRSRINDIFRLDDNS--LEFVGIQPTLEPPYESPVPIWLVVFGVVMGMIVIGIVVLIFTGIKDRRK 770 rabbit
NP_001132930 112 PKEEVERAV--RQSKHRINNAFLLSDMT--LEFVGVPPTLAVPIQYNTPPWLIVFGVVIGIVAVGIVALLMSTVSKRRR 186 zebrafish
XP_005997909 101 PENDVAEAI--RLNRHRINNAFLLSDKT--LQFIGIPPTLSPPVESSLPVWLILFGVVLGLVVIGIIFMIVTGIRQRKr 175 coelacanth
AAI61778     106 SYSVIEAAI--RNERNRINSAFLLDDKT--LEFVQIPPTLAPATQTSSSSWLIVFGVVVSVVTVAIAYLVVSGVIRHRK 180 tropical clawed ...
2_pfamImport  70 PQLLNEAGLhpRDLEEDVNHPRHLSSSTtpLDFLYI-PGLQHSTDGSEPHWLISYPVMDCCNVVITLILIVFAI----- 142
XP_001515621 136 PAGEVQAAI--RMNRNRINNAFFLNDQT--LEFLKIPSTLAPPTEPSVPVWMIVFGVVFCLVIIGIALLIMSGIQQHRR 210 platypus
XP_007500934 100 PAGEVQGAI--RMNRNRINNAFILNDQT--LEFLEIPATLGPPTEPSTPIWVIIFSVVFCLVIVGIVLLIVSGIRQRRR 174 gray short-taile...
XP_014584253  80 PAVEVQEAI--RMNRNRINNAFFLNDQT--LEFLKIPSTLIPPTDPPVPIWIIIFGVIFCIVIVAIILLILSGIRQRRR 154 horse
3_pfamImport  75 PADEIQSAI--RMNRNRINSAFSLNDQT--LEFLKIPSTLAPPTDPSVPIWIIIFGVVFCIVIVAITLLVLSGIRQRRR 149
XP_003218941 101 PKSVVEAAI--RLNRNRINSAFLLDDST--LQFLQISATLAPRVEPPVPTWLIVFGVSFCLVAVGIVLLIISGIHKNRR 175 green anole
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap