1F0X


Conserved Protein Domain Family
GlcD

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COG0277: GlcD (this model, PSSM-Id:223354 is obsolete and has been replaced by 440046)
FAD/FMN-containing dehydrogenase [Energy production and conversion]
linked to 3D-structure
Statistics
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PSSM-Id: 223354
Aligned: 171 rows
Threshold Bit Score: 88.4132
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1F0X_A    15 ELARLVGSSH----------LLTDPAKTARYRKGFR----SGQGDAL-------AVVFPGSLLELWRVLKACVTADKIIL 73  Escherichia coli
14600620   1 ------------------------MWPLWPLLVEKG-------FRPRa------YVAKPRSRGAVERIVEAAAEAGACLV 43  Aeropyrum pernix
20178205   8 IVDQLKEIVGadrvitdetvLKKNSIDRFRKFPDIHgi-yTLPIPAA-------VVKLG-STEQVSRVLNFMNAHKINGV 78  Escherichia coli O1...
15841744  56 ALARIVGTEYfrtadrdrllHAGGKSTPDLLRRKDTgv-qDAPDAVL-------LPGGPNGEDAVADILHYCSDHGIAVV 127 Mycobacterium tuber...
15842678  58 SLAALCSSDLvdr-----agHARGKAYRDIARNLQGql-dHLPDLIA-------RPRS---EQDVIDVLDWCAREGIAVI 121 Mycobacterium tuber...
15598222  38 SLEAALAKVPasrle-adprYSIDPRERLLHARGQSlp-dWLAMREGdfgvypdAVAYPETAEQIRELLALADSRDLQLI 115 Pseudomonas aerugin...
15609388  11 isappiatgcctpaasppqtccGAKTPVSRMR----------PTRCC-------CPAAPTGEDAVADILHYCSDHGIAVV 73  Mycobacterium tuber...
15610244  58 SLAALCSSDLvdr-----agHARGKAYRDIARNLQGql-dHLPDLIA-------RPRS---EQDVIDVLDWCAREGIAVI 121 Mycobacterium tuber...
15898358   1 -MQEFINEIQrn-------fSNCVVEDLDKYKRDWTplliLEEHLGKnlg-kplLVLSPSTTEEVSNIVKLANKYYVCIV 71  Sulfolobus solfatar...
15803290     --------------------------------------------------------------------------------     Escherichia coli O1...
1F0X_A    74 MQAANTGLTEGSTPNgNdydrdVVIISTLR-LDKLHVLG-KGEQVLAYPGTTLYSLEKALKPL-GREPHSVIGSScIGAS 150 Escherichia coli
14600620  44 PRGGGSNVVGASPPLg------CCLILDLRmLDKILWFSgEDLVVHVEAGAVVSKVEEWLNRR-GYTLGYHPQSQ-SLAT 115 Aeropyrum pernix
20178205  79 PRTGASATEGGLETVvEn----SVVLDGSA-MNQIINIDiENMQATAQCGVPLEVLENALR-EkGYTTGHSPQSK-PLAQ 151 Escherichia coli O1...
15841744 128 PFGGGTSVVGGLDPVrNdf-raVISLDMRR-FDRLHRIDeVSGEAELEAGVTGPEAERLLG-EhGFSLGHFPQSF-EFAT 203 Mycobacterium tuber...
15842678 122 PYGGGSSVVGGVEPr-Fde--pVVTVDVTA-MSAVLEIDrVSRAARIQAGAFGPSIEHQLR-PhDLTLRHFPQSF-GFST 195 Mycobacterium tuber...
15598222 116 PYGGGTSVAGHINPQaSrr--pVLTVSLER-MNRLIDLDrESLVATFGPGAAGPQVESQLRAL-GYTLGHFPQSW-ELST 190 Pseudomonas aerugin...
15609388  74 PFGGGTSVVGGLDPVrNdf-raVISLDMRR-FDRLHRIDeVSGEAELEAGVTGPEAERLLG-EhGFSLGHFPQSF-EFAT 149 Mycobacterium tuber...
15610244 122 PYGGGSSVVGGVEPr-Fde--pVVTVDVTA-MSAVLEIDrVSRAARIQAGAFGPSIEHQLR-PhDLTLRHFPQSF-GFST 195 Mycobacterium tuber...
15898358  72 PYGGGSSVVGGSYHNn------CVILDLSK-LNRIIEFNeEDLSVTVEVGIKIKDLEEWLNKR-GYTLDYHPQSF-YLAT 142 Sulfolobus solfatar...
15803290     --------------------------------------------------------------------------------     Escherichia coli O1...
1F0X_A   151 VIGGICNNSGGSLVQRGPAYTEMSLFARINEDGkltlvnhlgidlgetpeqilskldddrikdddvrhdgrhahdYDYVH 230 Escherichia coli
14600620 116 VGGSIAMLGSGALAPGLGNIEDMVLWLETVIPG------------------------------------------LGTVT 153 Aeropyrum pernix
20178205 152 MGGLVATRSIGQFSTLYGAIEDMVVGLEAVLADgt--------------------------------------vtRIKNV 193 Escherichia coli O1...
15841744 204 IGGFAATRSSGQDSAGYGRFNDMILGLRMITPVgv---------------------------------------lDLGRV 244 Mycobacterium tuber...
15842678 196 LGGWLATRSGGHFATLYTHIDDLTESLRIVTPVgi---------------------------------------sESRRL 236 Mycobacterium tuber...
15598222 191 LGGWVASRSSGQQSLRYGRIEQLFAGGTLETFA------------------------------------------GPLEI 228 Pseudomonas aerugin...
15609388 150 IGGFAATRSSGQDSAGYGRFNDMILGLRMITPVgv---------------------------------------lDLGRV 190 Mycobacterium tuber...
15610244 196 LGGWLATRSGGHFATLYTHIDDLTESLRIVTPVgi---------------------------------------sESRRL 236 Mycobacterium tuber...
15898358 143 IGGAIAHKGSG--SHSSSNIENLILWLEVILPN------------------------------------------GKAVK 178 Sulfolobus solfatar...
15803290     --------------------------------------------------------------------------------     Escherichia coli O1...
1F0X_A   231 RVRDIEAdTPARYNADPDRLFe-----SSGCAGKLAVFAVRLDTFEAEKNQQVFYIGTNQPEVLTEIRRHILAnfENLPv 305 Escherichia coli
14600620 154 LGSRNSPrGWEGPGVKHLFIG------SEGSLGVVVSAGLRVRPLPEFTGALAYRLPGFREGLEAARRLTLWR------- 220 Aeropyrum pernix
20178205 194 PRRAAGP-DIRHIIIGNEGALcyitevTVKIFKFTPENNLFYGYILEDMKTGFNILREIMVEG--YRPSIARLy-dAED- 268 Escherichia coli O1...
15841744 245 PASAAGP-DLRQLAIGSEGVFgvi-trVRLRVHRIPESTRYEAWSFPDFATGVAALRTITQTG--TGPTVVRLsdEAET- 319 Mycobacterium tuber...
15842678 237 PGSGAGP-SPDRLFLGSEGTLgii-teAWMRLQHRPRWQVTVSVVFDDWAAAVAATRTIAQAG--LYPANCRLldPAEA- 311 Mycobacterium tuber...
15598222 229 ATFPAS---AAGPDLRELVLG------SEGRFGIISSVKVRVSPLAEDERFYSVFLPNWQQALQATRELAQARvpLSMLr 299 Pseudomonas aerugin...
15609388 191 PASAAGP-DLRQLAIGSEGVFgvi-trVRLRVHRIPESTRYEAWSFPDFATGVAALRTITQTG--TGPTVVRLsdEAET- 265 Mycobacterium tuber...
15610244 237 PGSGAGP-SPDRLFLGSEGTLgii-teAWMRLQHRPRWQVTVSVVFDDWAAAVAATRTIAQAG--LYPANCRLldPAEA- 311 Mycobacterium tuber...
15898358 179 VGSSIR--TSMSPDLVRLFIG------SEGTLGVITKAKLRIFPLAPYHTDLSFLFPNFHNAIKFTREYV-----LRTS- 244 Sulfolobus solfatar...
15803290   1 ----------------------------MKIFKFTPENNLFYGYILEDMKTGFNILREIMVEG--YRPSIARLy-dAED- 48  Escherichia coli O1...
1F0X_A   306 ageYMHRDIYDIAEKygkdTFLMIDKLGT---DKMPFFFNlkgrtDAMLEKVKFFR-PHFTDRAMQKFGHLFPSHLpprm 381 Escherichia coli
14600620 221 ----GARLLRLLDPS-------EASMLYG-----VDG--------AVLMVEVEAPD--RGLLEAMEGYVEKVASAS---- 270 Aeropyrum pernix
20178205 269 ---GTQHFTHFADG---------KCVLIF---MAEGn--------PRIAKATGEGIaEIVARYPQCQRVDSKLIETw--- 322 Escherichia coli O1...
15841744 320 ---GVNLATTEAIG---------ETQITG---GCLG--ITvf--eGTQEHTESRHAeTRALLAARGGTSLG--EGPa--- 375 Mycobacterium tuber...
15842678 312 ---LLNAGTSVGGG---------LLVLAF---ESADHPIDpw--lHRAVAITAEHGgTVTAQRSRGTTSDAT-EHNa--- 370 Mycobacterium tuber...
15598222 300 ----LSNAVETMTQLalagHPGQIAWLEKylaLRGAGEGK-----CMLTFGVTGNR--RQNGLSLSQAKALLKRFGg--- 365 Pseudomonas aerugin...
15609388 266 ---GVNLATTEAIG---------ETQITG---GCLG--ITvf--eGTQEHTESRHAeTRALLAARGGTSLG--EGPa--- 321 Mycobacterium tuber...
15610244 312 ---LLNAGTSVGGG---------LLVLAF---ESADHPIDpw--lHRAVAITAEHGgTVTAQRSRGTTSDAT-EHNa--- 370 Mycobacterium tuber...
15898358 245 ----PPHRIVVHDKE-------SSEMMLN-----IPYN--------IALIRVRGYD-EDLVNVNEKIIRQLAMRHNa--- 296 Sulfolobus solfatar...
15803290  49 ---GTQHFTHFADG---------KCVLIF---MAEGn--------PRIAKATGEGIaEIVARYPQCQRVDSKLIETw--- 102 Escherichia coli O1...
1F0X_A   382 kNWRDKYEHHLLLK-MAGDGVGEAKSWLVDYFKQAEgdfFVCTPEEGSKAFLHRFAAAGAAIRYQAVHsdevedilALDI 460 Escherichia coli
14600620 271 ----GGSRVEGVYEkWARARYMYDEHVRQLWSAGLW---VDTIDTAAPWSRVEDLNRRLLEDLAGIPGv-------VAVM 336 Aeropyrum pernix
20178205 323 --FNNLNWGPDKVA-AERVQILKTGNMGFTTEVS-----GCWSCIHEIYESVINRIRTEFPHADDIt---------MLGG 385 Escherichia coli O1...
15841744 376 --RA-WERGRFAAP-YLRDSLLAAGALCETLETA-----TVWSNTPVLKAAVTEALTTSLAASGTPa---------LVMC 437 Mycobacterium tuber...
15842678 371 --AANWRSAFLRMP-YQRDALVRRGVIAETFETA-----CTWDGFDTLHAAVTDAARTAIWKVCGTg---------VVTC 433 Mycobacterium tuber...
15598222 366 -VFTGTLLGRKWAQnRFRFPYLREALWQAGYAVDTLetaTDWSNVDGLLQKIEASLRDGLAAEGEKv---------HVFT 435 Pseudomonas aerugin...
15609388 322 --RA-WERGRFAAP-YLRDSLLAAGALCETLETA-----TVWSNTPVLKAAVTEALTTSLAASGTPa---------LVMC 383 Mycobacterium tuber...
15610244 371 --AANWRSAFLRMP-YQRDALVRRGVIAETFETA-----CTWDGFDTLHAAVTDAARTAIWKVCGTg---------VVTC 433 Mycobacterium tuber...
15898358 297 -NEGDRSLIRSWREvFARKYEEQMTKIISQGLWN------DTLDLGATWSAMPKLYDKLKESLNSMKGi------kNVLS 363 Sulfolobus solfatar...
15803290 103 --FNNLNWGPDKVA-AERVQILKTGNMGFTTEVS-----GCWSCIHEIYESVINRIRTEFPHADDIt---------MLGG 165 Escherichia coli O1...
1F0X_A   461 ALRRNDTEWY-EHLPPEIDSQlvhkLYYGHFMCYVFHQDYIVKKGVDVHALKEQMLELLQQRGAQYPAEHNvghlyKAPE 539 Escherichia coli
14600620 337 SHAGHFYSGGaSLYHTVVMER--------RLDTYWRVWSRVAEAVRQLGASITHQHGWGLLRKPYLGFLGG------NYR 402 Aeropyrum pernix
20178205 386 HSSHSYQNGT-NMYFVYDYNVvnckPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHG-----SAWA 459 Escherichia coli O1...
15841744 438 HVSHVYPTGA-SLYFTVVAGQrg-dPIEQWLAAKKAASDAIMAT---GG-TITHHHAVGSDHRPWMRAEVGd----LGVT 507 Mycobacterium tuber...
15842678 434 RFTHVYPDGP-APYYGIYAGGrwgsLDAQWDEIKAAVSEAISAS---GG-TITHHHAVGRDHRAWYDRQRPd----PFAA 504 Mycobacterium tuber...
15598222 436 HLSHVYGEGSsIYTTYVFRPAa---SYAATLERWKRLKHAASQAIVDNRGTISHQHGVGKDHAPYLPREKGe----LGVA 508 Pseudomonas aerugin...
15609388 384 HVSHVYPTGA-SLYFTVVAGQrg-dPIEQWLAAKKAASDAIMAT---GG-TITHHHAVGSDHRPWMRAEVGd----LGVT 453 Mycobacterium tuber...
15610244 434 RFTHVYPDGP-APYYGIYAGGrwgsLDAQWDEIKAAVSEAISAS---GG-TITHHHAVGRDHRAWYDRQRPd----PFAA 504 Mycobacterium tuber...
15898358 364 RVTHVYTNGAsLYNVVVMEQD---------LELLKRVWETAARVIMQLGGTISHHHGVGILKKNWVKEELG-----EQYD 429 Sulfolobus solfatar...
15803290 166 HSSHSYQNGT-NMYFVYDYNVvnckPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHG-----SAWA 239 Escherichia coli O1...
1F0X_A   540 TLQKFYRENDPTNSMNPGIGKTSK 563 Escherichia coli
14600620 403 VFCRVKNTLDPGNVLNPNGISSRC 426 Aeropyrum pernix
20178205 460 LLEGLKKQFDPNGIMNTGTIYPIE 483 Escherichia coli O157:H7
15841744 508 LLRTIKATLDPAGILNPGKLIP-- 529 Mycobacterium tuberculosis CDC1551
15842678 505 ALRAAKSALDPAGILNPGVLLGR- 527 Mycobacterium tuberculosis CDC1551
15598222 509 ALRAMAGHFDPAGRLNRGTLLQD- 531 Pseudomonas aeruginosa PA01
15609388 454 LLRTIKATLDPAGILNPGKLIP-- 475 Mycobacterium tuberculosis H37Rv
15610244 505 ALRAAKSALDPAGILNPGVLLGR- 527 Mycobacterium tuberculosis H37Rv
15898358 430 LLLLIKRMIDSNNIMNPGKVFS-- 451 Sulfolobus solfataricus
15803290 240 LLEGLKKQFDPNGIMNTGTIYPIE 263 Escherichia coli O157:H7 EDL933
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